Gene name: folA
Protein name: Dihydrofolate reductase (EC
List of molecules and drugs that interact with protein P00381
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P00381_BDM | BDM | DB02809 | 5287754 | n/a | BRODIMOPRIM-4,6-DICARBOXYLATE | n/a | |
| 2 | P00381_MTX | MTX | DB00563 | 126941 | CHEMBL34259 | METHOTREXATE | n/a | Ki(nM) = 0.004 IC50(nM) = 0.0 |
| 3 | P00381_NDP | NDP | DB02338 | 5884;134821689; | CHEMBL407009 | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | n/a | |
| 4 | P00381_TMQ | TMQ | DB01157 | 5582;59961053; | n/a | TRIMETREXATE | n/a | IC50(nM) = 27.0 |
| 5 | P00381_TRR | TRR | DB03125 | 446998;3382784; | n/a | 2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM | n/a |