Gene name: HPRT1
Protein name: Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
List of molecules and drugs that interact with protein P00492
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P00492_1RP | 1RP | n/a | 60126677 | n/a | 6-fluoro-3-oxo-4-(5-O-phosphono-beta-D-ribofuranosyl)-3,4-dihydropyrazine-2-carboxamide | n/a | |
| 2 | P00492_24H | 24H | n/a | 73257;135542257; | CHEMBL419692 | {[(1S)-2-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-1-(hydroxymethyl)ethoxy]methyl}phosphonic acid | n/a | |
| 3 | P00492_25H | 25H | n/a | 11120209;135542507; | CHEMBL1229838 | {2-[2-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)ethoxy]ethyl}phosphonic acid | n/a | |
| 4 | P00492_3L3 | 3L3 | n/a | 137348149 | n/a | [(E)-2-(2-{[2-(2-amino-8-bromo-6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl][(E)-2-phosphonoethenyl]amino}ethoxy)ethenyl]phosphonic acid | n/a | |
| 5 | P00492_3L4 | 3L4 | n/a | 137348150 | n/a | [(2-{[2-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl][(E)-2-phosphonoethenyl]amino}ethoxy)methyl]phosphonic acid | n/a | |
| 6 | P00492_3L5 | 3L5 | n/a | 86341914;135566946; | CHEMBL3394316 | (2-{[2-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)ethyl][2-(2-phosphonoethoxy)ethyl]amino}ethyl)phosphonic acid | n/a | |
| 7 | P00492_3L6 | 3L6 | n/a | 86341915;135566947; | n/a | (2-{[2-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl](3-aminopropyl)amino}ethyl)phosphonic acid | n/a | |
| 8 | P00492_3L7 | 3L7 | n/a | 137348151 | n/a | (2-{[2-(6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl](2-{[(E)-2-phosphonoethenyl]oxy}ethyl)amino}ethyl)phosphonic acid | n/a | |
| 9 | P00492_3L8 | 3L8 | n/a | 86341917;135566949; | n/a | [(2-{[2-(6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl](2-phosphonoethyl)amino}ethoxy)methyl]phosphonic acid | n/a | |
| 10 | P00492_4X2 | 4X2 | n/a | 91936964;135567056; | n/a | (2-{[(2S)-1-hydroxy-3-(6-oxo-1,6-dihydro-9H-purin-9-yl)propan-2-yl]oxy}ethyl)phosphonic acid | n/a | |
| 11 | P00492_4X7 | 4X7 | n/a | 91885525;135567057; | CHEMBL4583093 | (2-{[(2S)-1-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-hydroxypropan-2-yl]oxy}ethyl)phosphonic acid | n/a | |
| 12 | P00492_5GP | 5GP | DB01972 | 6804;5280325;135398631; | CHEMBL283807 | GUANOSINE-5'-MONOPHOSPHATE | n/a | |
| 13 | P00492_8QI | 8QI | n/a | 162639717 | CHEMBL5221905 | ({(2S)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-2-[(2S)-2-hydroxy-2-phosphonoethoxy]propoxy}methyl)phosphonic acid | n/a | |
| 14 | P00492_9YP | 9YP | n/a | 129900193;135567347; | n/a | {[(2R)-2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methyl]-3-(2-phosphonoethoxy)propoxy]methyl}phosphonic acid | n/a | |
| 15 | P00492_H26 | H26 | n/a | 513620;135480704; | CHEMBL1233207 | {2-[2-(6-oxo-1,6-dihydro-9H-purin-9-yl)ethoxy]ethyl}phosphonic acid | n/a | |
| 16 | P00492_IMU | IMU | n/a | 444699;5288629;135461002; | CHEMBL1233603 | PHOSPHORIC ACID MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN-2-YLMETHYL] ESTER | n/a | |
| 17 | P00492_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 18 | P00492_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 19 | P00492_POP | POP | n/a | 4995;18628280;57345951; | n/a | PYROPHOSPHATE 2- | n/a | |
| 20 | P00492_PPO | PPO | DB03153 | 3318551;5289198;135403816; | n/a | 3H-PYRAZOLO[4,3-D]PYRIMIDIN-7-OL | n/a | |
| 21 | P00492_PRP | PRP | DB01632 | 7339 | n/a | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose | n/a | |
| 22 | P00492_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 23 | P00492_WPG | WPG | n/a | 129274005;135567406; | CHEMBL4277753 | (3-{(3R,4R)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-[(2R)-2-hydroxy-2-phosphonoethoxy]pyrrolidin-1-yl}-3-oxopropy l)phosphonic acid | n/a | |
| 24 | P00492_YPG | YPG | n/a | 123133743;135567138; | CHEMBL4290716 | [3-[(3~{R},4~{R})-3-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-[(2~{S})-2-oxidanyl-2-phosphono-ethoxy]pyrrolidin-1-y l]-3-oxidanylidene-propyl]phosphonic acid | n/a | |
| 25 | P00492_SV2 | SV2 | n/a | 23628455;135566801; | CHEMBL2325752 | [{2-[(guanine-9-yl)methyl]propane-1,3-diyl}bis(oxymethylene)]bis(phosphonic acid) | n/a | |
| 26 | P00492_PM6 | PM6 | DB01033 | 4071;667490; | CHEMBL1425 | Mercaptopurine | inhibitor | |
| 27 | P00492_XMP | XMP | DB02309 | n/a | n/a | 5-monophosphate-9-beta-D-ribofuranosyl xanthine | n/a | |
| 28 | P00492_9DG | 9DG | DB04356 | 100684;5287566;135461003; | CHEMBL367746 | 9-Deazaguanine | n/a |