Gene name: F10
Protein name: Coagulation factor X
List of molecules and drugs that interact with protein P00742
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P00742_0GJ | 0GJ | n/a | 137347860 | n/a | L-alpha-glutamyl-N-{(1S)-4-{[amino(iminio)methyl]amino}-1-[(1S)-2-chloro-1-hydroxyethyl]butyl}glycinamide | n/a | |
| 2 | P00742_230 | 230 | DB06920 | 11634458 | CHEMBL476186 | (2R,4R)-N~1~-(4-CHLOROPHENYL)-N~2~-[2-FLUORO-4-(2-OXOPYRIDIN-1(2H)-YL)PHENYL]-4-METHOXYPYRROLIDINE-1,2-DICARBOXAMIDE | inhibitor | IC50(nM) = 0.32 |
| 3 | P00742_237 | 237 | n/a | 16741235 | CHEMBL1229814 | (2R,4R)-N~1~-(4-CHLOROPHENYL)-N~2~-[3-FLUORO-2'-(METHYLSULFONYL)BIPHENYL-4-YL]-4-METHOXYPYRROLIDINE-1,2-DICARBOXAMIDE | n/a | |
| 4 | P00742_439 | 439 | n/a | 50919255 | CHEMBL1614790 | 6-CHLORO-N-{(3S)-1-[(1S)-1-(DIMETHYLAMINO)-2,3-DIHYDRO-1H-INDEN-5-YL]-2-OXO-3-PYRROLIDINYL}-2-NAPHTHALENESULFONAMIDE | n/a | |
| 5 | P00742_443 | 443 | DB11984 | 11641515 | CHEMBL1095032 | 1-(1-{(2S)-3-[(6-chloronaphthalen-2-yl)sulfonyl]-2-hydroxypropanoyl}piperidin-4-yl)tetrahydropyrimidin-2(1H)-one | inhibitor | |
| 6 | P00742_44I | 44I | n/a | 69329219 | n/a | 6-chloro-N-{(3S)-1-[(2S)-1-{(1R,5S)-7-[2-(methylamino)ethyl]-3,7-diazabicyclo[3.3.1]non-3-yl}-1-oxopropan-2-yl]-2-oxopy rrolidin-3-yl}naphthalene-2-sulfonamide | n/a | |
| 7 | P00742_455 | 455 | n/a | 11785929 | CHEMBL1221627 | (3R,4R)-1-SULFAMOYL-PYRROLIDINE-3,4-DICARBOXYLIC ACID 3-[(4-CHLORO-PHENYL)-AMIDE] 4-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYL]-AMIDE} | n/a | |
| 8 | P00742_461 | 461 | n/a | 11178928 | CHEMBL593584 | (E)-2-(5-CHLOROTHIOPHEN-2-YL)-N-[(3S)-1-{4-[(1R)-1-(DIMETHYLAMINO)ETHYL]-2-FLUOROPHENYL}-2-OXOPYRROLIDIN-3-YL]ETHENESULFONAMIDE | n/a | |
| 9 | P00742_48U | 48U | n/a | 46226324 | CHEMBL607085 | 4-[(3S)-3-({[(E)-2-(5-chlorothiophen-2-yl)ethenyl]sulfonyl}amino)-2-oxopyrrolidin-1-yl]-3-fluoro-N,N-dimethylbenzamide | n/a | |
| 10 | P00742_48W | 48W | n/a | 9849108 | n/a | 6-chloro-N-{(3S)-1-[(2S)-1-(4-methyl-5-oxo-1,4-diazepan-1-yl)-1-oxopropan-2-yl]-2-oxopyrrolidin-3-yl}naphthalene-2-sulf onamide | n/a | |
| 11 | P00742_4O1 | 4O1 | n/a | 69329613 | n/a | N~2~-[(6-chloronaphthalen-2-yl)sulfonyl]-N~2~-{(3S)-1-[(2S)-1-(4-methyl-1,4-diazepan-1-yl)-1-oxopropan-2-yl]-2-oxopyrrolidin-3-yl}glycinamide | n/a | |
| 12 | P00742_4O4 | 4O4 | n/a | 137348269 | n/a | 6-chloro-N-{(3S)-1-[(2S)-1-(morpholin-4-yl)-1-oxopropan-2-yl]-2-oxo-2,3-dihydro-1H-pyrrol-3-yl}-N-(2-oxobutyl)naphthalene-2-sulfonamide | n/a | |
| 13 | P00742_4O5 | 4O5 | n/a | 137348270 | n/a | 4-[(3S)-3-({[(E)-2-(5-chlorothiophen-2-yl)ethenyl]sulfonyl}amino)-2-oxo-2,3-dihydro-1H-pyrrol-1-yl]-3-fluoro-N-methylbenzamide | n/a | |
| 14 | P00742_4O6 | 4O6 | n/a | 9803364 | CHEMBL223891 | (E)-2-(4-chlorophenyl)-N-{(3S)-1-[(2S)-1-(morpholin-4-yl)-1-oxopropan-2-yl]-2-oxopyrrolidin-3-yl}ethenesulfonamide | n/a | |
| 15 | P00742_4PP | 4PP | n/a | 5496928 | CHEMBL105532 | (2S)-(3'-AMIDINO-3-BIPHENYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID | n/a | |
| 16 | P00742_4QC | 4QC | n/a | 9549214 | CHEMBL222079 | 3-[6-{2'-[(DIMETHYLAMINO)METHYL]BIPHENYL-4-YL}-7-OXO-3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3,4-C]PYRIDIN-1-YL]BENZAMIDE | n/a | |
| 17 | P00742_5QC | 5QC | n/a | 6914623 | CHEMBL378093 | 1-(3-AMINO-1,2-BENZISOXAZOL-5-YL)-6-(2'-{[(3R)-3-HYDROXYPYRROLIDIN-1-YL]METHYL}BIPHENYL-4-YL)-3-(TRIFLUOROMETHYL)-1,4,5,6-TETRAHYDRO-7H-PYRAZOLO[3,4-C]PYRIDIN-7-ONE | n/a | |
| 18 | P00742_63C | 63C | n/a | 11329945 | n/a | (3R,4R)-1-METHYLCARBAMOYLMETHYL-PYRROLIDINE-3,4-DICARBOXYLIC ACID 3-[(4-CHLORO-PHENYL)-AMIDE] 4-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYL]-AMIDE} | n/a | |
| 19 | P00742_663 | 663 | n/a | 16750067 | n/a | 3-CHLORO-N-(4-CHLORO-2-{[(5-CHLOROPYRIDIN-2-YL)AMINO]CARBONYL}-6-METHOXYPHENYL)-4-[(1-METHYL-1H-IMIDAZOL-2-YL)METHYL]THIOPHENE-2-CARBOXAMIDE | n/a | |
| 20 | P00742_6PK | 6PK | n/a | 9937041 | CHEMBL4238121 | O-benzyl-N-(benzylsulfonyl)-D-seryl-N-[(4-carbamimidoylphenyl)methyl]glycinamide | n/a | |
| 21 | P00742_6XS | 6XS | n/a | 72200999 | CHEMBL3091502 | 5-Chloro-thiophene-2-carboxylic acid [(S)-2-[2-chloro-5-fluoro-3-(2-oxo-piperidin-1-yl)-benzenesulfonylamino]-3-(4-methyl-piperazin-1-yl)-3-oxo-propyl]-amide | n/a | |
| 22 | P00742_701 | 701 | DB07211 | 10095865 | CHEMBL391640 | (2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}PROPENE-1-SULFONAMIDE | n/a | Ki(nM) = 2.0 |
| 23 | P00742_784 | 784 | n/a | 4369605 | n/a | [AMINO (4-{(3AS,4R,8AS,8BR)-1,3-DIOXO-2- [3-(TRIMETHYLAMMONIO) PROPYL]DECAHYDROPYRROLO[3,4-A] PYRROLIZIN-4-YL}PHENYL) METHYLENE]AMMONIUM | n/a | |
| 24 | P00742_7R9 | 7R9 | n/a | 72206621 | CHEMBL3091501 | 5-Chloro-thiophene-2-carboxylic acid [(S)-2-[2-difluoromethoxy-3-(2-oxo-piperidin-1-yl)-benzenesulfonylamino]-3-((S)-3-dimethylamino-pyrrolidin-1-yl)-3-oxo-propyl]-amide | n/a | |
| 25 | P00742_815 | 815 | DB07261 | 445480 | CHEMBL316053 | THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [1-(1-AMINO-ISOQUINOLIN-7-YLMETHYL)-2-OXO-PYRROLDIN-3-YL]-AMIDE | n/a | Ki(nM) = 22.0 |
| 26 | P00742_894 | 894 | DB07277 | 10343728 | CHEMBL391737 | 2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHANESULFONAMIDE | n/a | Ki(nM) = 154.0 |
| 27 | P00742_895 | 895 | DB07278 | 9911502 | CHEMBL220050 | 2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHENESULFONAMIDE | inhibitor | Ki(nM) = 4.0 |
| 28 | P00742_898 | 898 | n/a | 11454249 | CHEMBL595477 | (E)-2-(5-CHLOROTHIOPHEN-2-YL)-N-[(3S)-1-{4-[(1S)-1-(DIMETHYLAMINO)ETHYL]-2-FLUOROPHENYL}-2-OXOPYRROLIDIN-3-YL]ETHENESULFONAMIDE | n/a | |
| 29 | P00742_8NC | 8NC | n/a | 46835134 | CHEMBL1222019 | (3R,4R)-1-METHANESULFONYL-PYRROLIDINE-3,4--DICARBOXYLIC ACID 3-[(3-FLUORO-4-METHOXY-PHENYL)-AMIDE] 4-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYL]-AMIDE} | n/a | |
| 30 | P00742_930 | 930 | n/a | 50919257 | CHEMBL1614818 | 6-CHLORO-N-((3S)-2-OXO-1-{4-[(2S)-2-PYRROLIDINYL]PHENYL}-3-PYRROLIDINYL)-2-NAPHTHALENESULFONAMIDE | n/a | |
| 31 | P00742_931 | 931 | n/a | 50919256 | CHEMBL1614819 | 6-CHLORO-N-((3S)-2-OXO-1-{4-[(2R)-2--PYRROLIDINYL] PHENYL}-3-PYRROLIDINYL)-2-NAPHTHALENESULFONAMIDE | n/a | |
| 32 | P00742_987 | 987 | n/a | 69329865 | n/a | N-[(3S)-1-{(2S)-1-[(3S)-3-aminopiperidin-1-yl]-1-oxopropan-2-yl}-2-oxopyrrolidin-3-yl]-6-chloronaphthalene-2-sulfonamid e | n/a | |
| 33 | P00742_993 | 993 | n/a | 18376720 | CHEMBL427421 | 3-CHLORO-4-(2-METHYLAMINO-IMIDAZOL-1-YLMETHYL)-THIOPHENE-2-CARBOXYLIC ACID [4-CHLORO-2-(5-CHLORO-PYRIDIN-2-YLCARBAMOYL)-6-METHOXY-PHENYL]-AMIDE | n/a | |
| 34 | P00742_A7I | A7I | n/a | 11990478 | CHEMBL5291366 | 5-CHLORO-THIOPHENE-2-CARBOXYLIC ACID [2-(1--ISOPROPYL-PIPERIDIN-4-YLSULFAMOYL)-ETHYL]-AMIDE | n/a | |
| 35 | P00742_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 36 | P00742_BI7 | BI7 | n/a | 25113610 | CHEMBL1626802 | 3-[(3~{a}~{S},4~{R},8~{a}~{S},8~{b}~{R})-4-[5-(5-chloranylthiophen-2-yl)-1,2-oxazol-3-yl]-1,3-bis(oxidanylidene)-4,6,7,8,8~{a},8~{b}-hexahydro-3~{a}~{H}-pyrrolo[3,4-a]pyrrolizin-2-yl]propyl-trimethyl-azanium | n/a | |
| 37 | P00742_C0Z | C0Z | n/a | 50919254 | CHEMBL1614872 | 6-CHLORO-N-[(3S)-1-[(1S)-1-DIMETHYLAMINO-2,3-DIHYDRO-1H-INDEN-5-YL]-2-OXO-PYRROLIDIN-3-YL]NAPHTHALENE-2-SULFONAMIDE | n/a | |
| 38 | P00742_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 39 | P00742_CBB | CBB | n/a | 446979 | CHEMBL92836 | 1-(3-CARBAMIMIDOYL-BENZYL)-1H-INDOLE-2-CARBOXYLIC ACID 3-CARBAMIMIDOYL-BENZYLESTER | n/a | |
| 40 | P00742_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 41 | P00742_CMB | CMB | n/a | 446982 | CHEMBL92776 | 1-(3-carbamimidoylbenzyl)-N-(3,5-dichlorobenzyl)-4-methyl-1H-indole-2-carboxamide | n/a | |
| 42 | P00742_CMI | CMI | n/a | 446984 | CHEMBL93087 | 1-(3-CARBAMIMIDOYL-BENZYL)-4-METHYL-1H-INDOLE-2-CARBOXYLIC ACID 3,5-DIMETHYL-BENZYLAMIDE | n/a | |
| 43 | P00742_D01 | D01 | DB07605 | 9547923 | n/a | 2-({4-[(5-CHLORO-1H-INDOL-2-YL)SULFONYL]PIPERAZIN-1-YL}CARBONYL)THIENO[3,2-B]PYRIDINE 4-OXIDE | n/a | |
| 44 | P00742_D14 | D14 | n/a | 44520929 | CHEMBL593603 | 7-chloro-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-{[(5-methyl-5,6-dihydro-4H-pyrrolo[3,4-d][1,3]thiazol-2-yl)carbonyl]amino}cyclohexyl]isoquinoline-3-carboxamide | n/a | |
| 45 | P00742_D1Q | D1Q | n/a | 25052256 | CHEMBL1923888 | 4-{3-[(4-chlorophenyl)amino]-3-oxopropyl}-3-({[5-(propan-2-yl)-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl]carbonyl}amino)benzoic acid | n/a | |
| 46 | P00742_D46 | D46 | n/a | 24936173 | CHEMBL1681798 | N-[2-({[(5-chlorothiophen-2-yl)carbonyl]amino}methyl)phenyl]-5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carboxamide | n/a | |
| 47 | P00742_D76 | D76 | n/a | 448997 | n/a | (2R)-4-[(6-CHLORO-2-NAPHTHYL)SULFONYL]-1-[(5-METHYL-4,5,6,7-TETRAHYDRO[1,3]THIAZOLO[5,4-C]PYRIDIN-2-YL)CARBONYL]PIPERAZ INE-2-CARBOXAMIDE | n/a | |
| 48 | P00742_D90 | D90 | n/a | 54581294 | CHEMBL1761615 | N-(2-{[(5-chloro-1H-indol-2-yl)carbonyl]amino}phenyl)-5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carboxamide | n/a | |
| 49 | P00742_D91 | D91 | DB04673 | 49866889 | n/a | 5-CHLORO-2-({3-ISOBUTYL-4-[(5-PYRIDIN-4-YLPYRIMIDIN-2-YL)CARBONYL]PIPERAZIN-1-YL}SULFONYL)-1H-INDOLE | n/a | |
| 50 | P00742_D92 | D92 | DB07629 | 24752832 | CHEMBL245678 | N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE | n/a | IC50(nM) = 16.0 |
| 51 | P00742_D93 | D93 | DB07630 | 24752833 | CHEMBL391805 | N-((1R,2R)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE | n/a | IC50(nM) = 13.0 |
| 52 | P00742_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 53 | P00742_DT8 | DT8 | n/a | 9808346 | CHEMBL479863 | N-((1R,2S,5S)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)-5-(DIMETHYLCARBAMOYL)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE | n/a | |
| 54 | P00742_DX9 | DX9 | n/a | n/a | n/a | (2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-[4-({(3R)-1-[(1Z)-ethanimidoyl]pyrrolidin-3-yl}oxy)phenyl]propanoic acid | n/a | |
| 55 | P00742_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 56 | P00742_ENS | ENS | n/a | 25138140 | CHEMBL459141 | methyl (2Z)-3-[(3-chloro-1H-indol-7-yl)amino]-2-cyano-3-{[(3S)-2-oxo-1-(2-oxo-2-pyrrolidin-1-ylethyl)azepan-3-yl]amino}acrylate | n/a | |
| 57 | P00742_FFG | FFG | n/a | 46232667;136066129; | CHEMBL577677 | (R)-6-(2'-((3-hydroxypyrrolidin-1-yl)methyl)biphenyl-4-yl)-1-(3-(5-oxo-4,5-dihydro-1h-1,2,4-triazol-3-yl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1h-pyrazolo[3,4-c]pyridin-7(4h)-one | n/a | |
| 58 | P00742_FI1 | FI1 | n/a | 53488415 | CHEMBL1923468 | 6-chloro-N-((3S)-2-oxo-1-(2-oxo-2-((5S)-8-oxo-5,6-dihydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(2H,4H,8H)-yl)ethyl)piperidin-3-yl)naphthalene-2-sulfonamide | n/a | |
| 59 | P00742_FJD | FJD | n/a | 54751669 | CHEMBL4283525 | 3-[(3AS,4R,5S,8AS,8BR)-4-[5-(5-CHLOROTHIOPHEN-2-YL)-1,3-OXAZOL-2-YL]-1,3-DIOXO-4,6,7,8,8A,8B-HEXAHYDRO-3AH-PYRROLO[3,4-A]PYRROLIZIN-2-YL]PROPYL-TRIMETHYL-AZANIUM | n/a | |
| 60 | P00742_FXA | FXA | DB07800 | 24794406 | CHEMBL402761 | N-(2-(((5-CHLORO-2-PYRIDINYL)AMINO)SULFONYL)PHENYL)-4-(2-OXO-1(2H)-PYRIDINYL)BENZAMIDE | n/a | Ki(nM) = 5.5 |
| 61 | P00742_FXI | FXI | n/a | 16741240 | n/a | 1-(butyl{[(4-chlorophenyl)amino]carbonyl}amino)-N-[3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl]cyclopropanecarboxamide | n/a | |
| 62 | P00742_FXV | FXV | n/a | 6323322 | n/a | METHYL-3-(4'-N-OXOPYRIDYLPHENOYL)-3-METHYL-2-(M-AMIDINOBENZYL)-PROPIONATE | n/a | |
| 63 | P00742_G15 | G15 | DB07804 | 16040261 | CHEMBL220513 | 5-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1H-1,2,4-TRIAZOLE-3-SULFONAMIDE | n/a | |
| 64 | P00742_GG2 | GG2 | DB06605 | 10182969 | CHEMBL231779 | 1-(4-METHOXYPHENYL)-7-OXO-6-[4-(2-OXOPIPERIDIN-1-YL)PHENYL]-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3,4-C]PYRIDINE-3-CARBOXAMIDE | inhibitor | Ki(nM) = 0.075 IC50(nM) = 2.3 |
| 65 | P00742_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 66 | P00742_GS5 | GS5 | DB07843 | 9549259 | CHEMBL220529 | 5-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1-BENZOTHIOPHENE-2-SULFONAMIDE | n/a | Ki(nM) = 47.0 |
| 67 | P00742_GS6 | GS6 | DB07844 | 9549258 | CHEMBL217914 | 6-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1-BENZOTHIOPHENE-2-SULFONAMIDE | n/a | Ki(nM) = 15.0 |
| 68 | P00742_GSI | GSI | n/a | 25058127 | n/a | 2-(5-chlorothiophen-2-yl)-N-[(3S)-1-(4-{2-[(dimethylamino)methyl]-1H-imidazol-1-yl}-2-fluorophenyl)-2-oxopyrrolidin-3-yl]ethanesulfonamide | n/a | |
| 69 | P00742_GSJ | GSJ | n/a | 9549260 | CHEMBL373451 | 1-PYRROLIDINEACETAMIDE, 3-[[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]AMINO]-ALPHA-METHYL-N-(1-METHYLETHYL)-N-[2-[(METHYLSULFONYL)AMINO]ETHYL]-2-OXO-, (ALPHAS,3S)- | n/a | |
| 70 | P00742_GSK | GSK | DB07847 | 6852168 | CHEMBL385587 | 6-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-(4-MORPHOLINYL)-2-OXO ETHYL]-2-OXO-3-PYRROLIDINYL}-2-NAPHTHALENESULFONAMIDE | n/a | Ki(nM) = 6.0 |
| 71 | P00742_GSQ | GSQ | DB07848 | 9549257 | CHEMBL375112 | 5-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-5-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-SULFONAMIDE | n/a | Ki(nM) = 90.0 |
| 72 | P00742_GSV | GSV | n/a | 25113113 | n/a | 2-(5-chlorothiophen-2-yl)-N-{(3S)-1-[3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl]-2-oxopyrrolidin-3-yl}ethanesulfonamide | n/a | |
| 73 | P00742_GSX | GSX | n/a | 10118017 | CHEMBL220171 | 5'-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-2,2'-BITHIOPHENE-5-SULFONAMIDE | n/a | |
| 74 | P00742_H21 | H21 | n/a | 11561914 | CHEMBL564248 | 5-chloro-N-[1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)-1H-1,2,4-triazol-3-yl]thiophene-2-carboxamide | n/a | |
| 75 | P00742_H22 | H22 | DB07872 | 42628060 | CHEMBL557915 | 5-chloro-N-[(3R)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)pyrrolidin-3-yl]thiophene-2-carboxamide | n/a | Ki(nM) = 8.0 |
| 76 | P00742_H25 | H25 | DB07875 | 11979006 | CHEMBL561318 | 5-Chloro-thiophene-2-carboxylic acid ((3S,4S)-1-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenylcarbamoyl]-methyl}-4-hydroxy-pyrrolidin-3-yl)-amide | n/a | Ki(nM) = 10.0 |
| 77 | P00742_I1H | I1H | n/a | 6420136 | CHEMBL96434 | 3-[2-(2,4-DICHLOROPHENYL)ETHOXY]-4-METHOXY-N-[(1-PYRIDIN-4-YLPIPERIDIN-4-YL)METHYL]BENZAMIDE | n/a | |
| 78 | P00742_IIA | IIA | n/a | 6540265 | CHEMBL182746 | 1-{[5-(5-CHLORO-2-THIENYL)ISOXAZOL-3-YL]METHYL}-N-(1-ISOPROPYLPIPERIDIN-4-YL)-1H-INDOLE-2-CARBOXAMIDE | n/a | |
| 79 | P00742_IIB | IIB | n/a | 6540266 | CHEMBL191394 | 1-{[5-(5-CHLORO-2-THIENYL)ISOXAZOL-3-YL]METHYL}-3-CYANO-N-(1-ISOPROPYLPIPERIDIN-4-YL)-7-METHYL-1H-INDOLE-2-CARBOXAMIDE | n/a | |
| 80 | P00742_IID | IID | DB07973 | 6540267 | CHEMBL182323 | N-(1-ISOPROPYLPIPERIDIN-4-YL)-1-(3-METHOXYBENZYL)-1H-INDOLE-2-CARBOXAMIDE | n/a | Ki(nM) = 89.0 |
| 81 | P00742_IIE | IIE | DB07974 | 6540268 | CHEMBL368238 | 1-{2-[(4-CHLOROPHENYL)AMINO]-2-OXOETHYL}-N-(1-ISOPROPYLPIPERIDIN-4-YL)-1H-INDOLE-2-CARBOXAMIDE | n/a | Ki(nM) = 3.0 |
| 82 | P00742_IK8 | IK8 | n/a | 204102 | CHEMBL206335 | 1-(3-AMINO-1,2-BENZISOXAZOL-5-YL)-N-(4-{2-[(DIMETHYLAMINO)METHYL]-1H-IMIDAZOL-1-YL}-2-FLUOROPHENYL)-3-(TRIFLUOROMETHYL) -1H-PYRAZOLE-5-CARBOXAMIDE | n/a | |
| 83 | P00742_IMA | IMA | DB02269 | 446978 | CHEMBL1190476 | [4-({[5-BENZYLOXY-1-(3-CARBAMIMIDOYL-BENZYL)-1H-INDOLE-2-CARBONYL]-AMINO}-METHYL)-PHENYL]-TRIMETHYL-AMMONIUM | n/a | Ki(nM) = 82.0 |
| 84 | P00742_IVK | IVK | n/a | 46835135 | CHEMBL1221628 | (3R,4R)-N-(4-CHLOROPHENYL)-N'-[2-FLUORO-4-(2-OXOPYRIDIN-1(2H)-YL)PHENYL]-1-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-3,4-DICARBOXAMIDE | n/a | |
| 85 | P00742_JNJ | JNJ | n/a | 16720561 | CHEMBL398870 | 1-(3-amino-1,2-benzisoxazol-5-yl)-6-(4-{2-[(dimethylamino)methyl]-1H-imidazol-1-yl}-2-fluorophenyl)-7-fluoro-1H-indazole-3-carboxamide | n/a | |
| 86 | P00742_L1C | L1C | n/a | 25210468 | CHEMBL474678 | (2R,4S)-N^1^-(4-chlorophenyl)-4-(2,4-difluorophenyl)-4-hydroxy-N^2^-(2-oxo-2H-1,3'-bipyridin-6'-yl)pyrrolidine-1,2-dicarboxamide | n/a | |
| 87 | P00742_L1D | L1D | n/a | 25210469 | CHEMBL515107 | (2R,4S)-N^1^-(4-chlorophenyl)-N^2^-[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]-4-hydroxy-4-phenylpyrrolidine-1,2-dicarboxamide | n/a | |
| 88 | P00742_LG0 | LG0 | n/a | 24836819 | CHEMBL461091 | 1-(4-methoxyphenyl)-6-(4-(1-(pyrrolidin-1-ylmethyl)cyclopropyl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1H-pyrazolo[3,4-c]pyridin-7(4H)-one | n/a | |
| 89 | P00742_LGJ | LGJ | n/a | 10232074;135530746; | CHEMBL591955 | N-(3-FLUORO-2'-(METHYLSULFONYL)BIPHENYL-4-YL)-1-(3-(5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-3-YL)PHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-5-CARBOXAMIDE | n/a | |
| 90 | P00742_LGK | LGK | n/a | 18677468;135740055; | CHEMBL578474 | 6-(2'-(METHYLSULFONYL)BIPHENYL-4-YL)-1-(3-(5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-3-YL)PHENYL)-3-(TRIFLUOROMETHYL)-5,6-DIHYDRO-1H-PYRAZOLO[3,4-C]PYRIDIN-7(4H)-ONE | n/a | |
| 91 | P00742_LGL | LGL | n/a | 18677450;135740054; | CHEMBL578098 | 1-(3-(5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-3-YL)PHENYL)-6-(2'-(PYRROLIDIN-1-YLMETHYL)BIPHENYL-4-YL)-3-(TRIFLUOROMETHYL)-5,6-DIHYDRO-1H-PYRAZOLO[3,4-C]PYRIDIN-7(4H)-ONE | n/a | |
| 92 | P00742_LGM | LGM | n/a | 46232668;136066130; | CHEMBL578906 | 3-METHYL-1-(3-(5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-3-YL)PHENYL)-6-(2'-(PYRROLIDIN-1-YLMETHYL)BIPHENYL-4-YL)-5,6-DIHYDRO-1H-PYRAZOLO[3,4-C]PYRIDIN-7(4H)-ONE | n/a | |
| 93 | P00742_LZF | LZF | n/a | 11979007 | CHEMBL551393 | 5-chloro-N-[(3S,4S)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)-4-methoxypyrrolidin-3-yl]thiophene-2-carboxamide | n/a | |
| 94 | P00742_LZG | LZG | DB08143 | 42628063 | CHEMBL550453 | 5-CHLORO-THIOPHENE-2-CARBOXYLIC ACID ((3S,4S)-4-FLUORO- 1-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYLCARBAMOYL]-METHYL}-PYRROLIDIN-3-YL)-AMIDE | n/a | Ki(nM) = 31.0 |
| 95 | P00742_LZH | LZH | n/a | 42628061 | CHEMBL550102 | 5-CHLORO-THIOPHENE-2-CARBOXYLIC ACID ((3R,5S)-1-{[2-FLUORO-4-(2-OXO-PYRIDIN-1-YL)-PHENYLCARBAMOYL]-METHYL}-5-HYDROXYMETHYL-PYRROLIDIN-3-YL)-AMIDE | n/a | |
| 96 | P00742_LZI | LZI | n/a | 42628062 | CHEMBL563458 | (4R)-4-{[(5-chlorothiophen-2-yl)carbonyl]amino}-N-(cyclopropylmethyl)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)-L-prolinamide | n/a | |
| 97 | P00742_M35 | M35 | n/a | 9895762 | CHEMBL176140 | 1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide | n/a | |
| 98 | P00742_M37 | M37 | n/a | 9915041 | CHEMBL151939 | 1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoylbiphenyl-4-yl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide | n/a | |
| 99 | P00742_MBM | MBM | n/a | 44473086 | CHEMBL567904 | N-{N'-(2-methyl-1-benzofuran-5-yl)-N-[(3S)-2-oxo-1-(2-oxo-2-pyrrolidin-1-ylethyl)azepan-3-yl]carbamimidoyl}pyridine-3-carboxamide | n/a | |
| 100 | P00742_ME1 | ME1 | DB08173 | 10250490 | CHEMBL232566 | 5-CHLORO-N-(2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO)ETHYL)THIOPHENE-2-CARBOXAMIDE | n/a | Ki(nM) = 1.5 |
| 101 | P00742_ME4 | ME4 | n/a | 11237163 | CHEMBL398380 | 3-CHLORO-N-((1R,2S) -2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO)CYCLOHEXYL)-1H-INDOLE-6-CARBOXAMIDE | n/a | |
| 102 | P00742_ME5 | ME5 | DB08174 | 9954980 | CHEMBL233992 | 5-CHLORO-N-((1R,2S)-2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO) CYCLOPENTYL)THIOPHENE-2-CARBOXAMIDE | n/a | Ki(nM) = 0.43 |
| 103 | P00742_MES | MES | DB03814 | 78165;4478249; | CHEMBL1234276 | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | n/a | |
| 104 | P00742_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 105 | P00742_MZA | MZA | n/a | 11950431 | CHEMBL1615104 | 6-CHLORO-N-[(3S)-1-(5-FLUORO-1,2,3,4-TETRAHYDROISOQUINOLIN-6-YL)-2-OXO-PYRROLIDIN-3-YL]NAPHTHALENE-2-SULFONAMIDE | n/a | |
| 106 | P00742_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 107 | P00742_OYJ | OYJ | n/a | 11238193 | CHEMBL1222130 | (3R,4R)-1-METHANESULFONYL-PYRROLIDINE-3,4-DICARBOXYLIC ACID 3-[(4-CHLORO-3-FLUORO-PHENYL)-AMIDE] 4-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYL]-AMIDE} | n/a | |
| 108 | P00742_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 109 | P00742_PR2 | PR2 | DB08426 | 445481 | CHEMBL1235423 | THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL]-AMIDE | n/a | Ki(nM) = 18.0 |
| 110 | P00742_R11 | R11 | DB02354 | 445756 | n/a | 4-{[1-METHYL-5-(2-METHYL-BENZOIMIDAZOL-1-YLMETHYL)-1H-BENZOIMIDAZOL-2-YLMETHYL]-AMINO}-BENZAMIDINE | n/a | Ki(nM) = 40.0 |
| 111 | P00742_RDR | RDR | n/a | 447361 | CHEMBL157813 | 4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-1-{[1-(2-HYDROXYETHYL)-1H-PYRROLO[3,2-C]PYRIDIN-2-YL]METHYL}PIPERAZIN-2-ONE | n/a | |
| 112 | P00742_RIV | RIV | DB06228 | 9875401 | CHEMBL198362 | 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide | antagonist | |
| 113 | P00742_RPR | RPR | DB04424 | 5497056 | CHEMBL48046 | 3-[(3'-AMINOMETHYL-BIPHENYL-4-CARBONYL)-AMINO]-2-(3-CARBAMIMIDOYL-BENZYL)-BUTYRIC ACID METHYL ESTER | n/a | Ki(nM) = 0.9 |
| 114 | P00742_RR8 | RR8 | n/a | 11455408 | CHEMBL1221534 | (3R,4R)-1-METHANESULFONYL-PYRROLIDINE-3,4-DICARBOXYLIC ACID 3-[(4-CHLORO-PHENYL)-AMIDE] 4-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYL]-AMIDE} | n/a | |
| 115 | P00742_RRP | RRP | DB08487 | 447359 | CHEMBL351298 | 3-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE | n/a | Ki(nM) = 4.0 |
| 116 | P00742_RRR | RRR | DB08488 | 447360 | n/a | 4-{[(E)-2-(5-CHLOROTHIEN-2-YL)VINYL]SULFONYL}-1-(1H-PYRROLO[3,2-C]PYRIDIN-2-YLMETHYL)PIPERAZIN-2-ONE | n/a | |
| 117 | P00742_RTR | RTR | DB08495 | 447362 | CHEMBL48813 | 4-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE | n/a | Ki(nM) = 1.0 |
| 118 | P00742_RUP | RUP | n/a | n/a | n/a | (R)-2-(3-ADAMANTAN-1-YL-UREIDO)-3-(3-CARBAMIMIDOYL-PHENYL)-N-PHENETHYL-PROPIONAMIDE | n/a | |
| 119 | P00742_VYR | VYR | n/a | 66911194 | CHEMBL3091505 | N-[(S)-1-[5-(5-Chloro-thiophen-2-yl)-isoxazol-3-ylmethyl]-2-(4-methoxy-piperidin-1-yl)-2-oxo-ethyl]-2-ethyl-3-(3-oxo-morpholin-4-yl)-benzenesulfonamide | n/a | |
| 120 | P00742_XBV | XBV | n/a | 24849206 | CHEMBL1221913 | (3R,4R)-1-(2,2-DIFLUORO-ETHYL)-PYRROLIDINE-3,4-DICARBOXYLIC ACID 3-[(5-CHLORO-PYRIDIN-2-YL)-AMIDE]-4-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYL]-AMIDE} | n/a | |
| 121 | P00742_XLC | XLC | n/a | 447193 | CHEMBL227121 | 3-CHLORO-N-[4-CHLORO-2-[[(4-CHLOROPHENYL)AMINO]CARBONYL]PHENYL]-4-[(4-METHYL-1-PIPERAZINYL)METHYL]-2-THIOPHENECARBOXAMIDE | n/a | |
| 122 | P00742_XLD | XLD | n/a | 3400921 | CHEMBL173994 | 3-CHLORO-N-[4-CHLORO-2-[[(5-CHLORO-2-PYRIDINYL)AMINO]CARBONYL]-6-METHOXYPHENYL]-4-[[(4,5-DIHYDRO-2-OXAZOLYL)METHYLAMINO]METHYL]-2-THIOPHENECARBOXAMIDE | n/a | |
| 123 | P00742_XMA | XMA | n/a | 446331 | n/a | (-)-7-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]TETRAHYDRO-8A-(METHOXYMETHYL)-1'-(4-PYRIDINYL)-SPIRO[5H-OXAZOLO[3,2-A]PYRAZINE-2(3H),4'-PIPERIDIN]-5-ONE | n/a | |
| 124 | P00742_XMB | XMB | n/a | 446338 | n/a | 4-[(2R)-3-[[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]AMINO]-1-OXO-2-[[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]AMINO]PROPYL]-THIOMORPHOLINE-1,1-DIOXIDE | n/a | |
| 125 | P00742_XMC | XMC | n/a | 446347 | n/a | 4-[[4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-6-OXO-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]-2-PIPERAZINYL]CARBONYL]MORPHOLINE | n/a | |
| 126 | P00742_XMD | XMD | n/a | 5289584 | n/a | (2R)-4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-6-OXO-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]-2-PIPERAZINECARBOXYLIC ACID ETHYL ESTER | n/a | |
| 127 | P00742_XME | XME | n/a | 9600424 | n/a | 4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-1-[[4-HYDROXYIMINOMETHYL-1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINONE | n/a | |
| 128 | P00742_XMF | XMF | n/a | 5289586 | n/a | 4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-1-[[4-HYDROXYMETHYL-1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINONE | n/a | |
| 129 | P00742_XMG | XMG | n/a | 446342 | n/a | 4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL] METHYL]-2-PIPERAZINECARBOXYLIC ACID | n/a | |
| 130 | P00742_XMH | XMH | n/a | 446343 | n/a | 4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]-2-PIPERAZINECARBOXYLIC ACID ETHYL ESTER | n/a | |
| 131 | P00742_XMI | XMI | n/a | 446344 | n/a | 4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINONE | n/a | |
| 132 | P00742_XMJ | XMJ | DB08745 | 446345 | n/a | 4-[[(1E)-2-(4-CHLOROPHENYL)ETHENYL]SULFONYL]-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINONE | n/a | |
| 133 | P00742_XMK | XMK | DB08746 | 446346 | n/a | 1-[[(1E)-2-(4-CHLOROPHENYL)ETHENYL]SULFONYL]-4-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINE | n/a | |
| 134 | P00742_XWG | XWG | n/a | 54751668 | CHEMBL5266057 | (3AS,4R,5S,8AS,8BR)-4-[5-(5-CHLOROTHIOPHEN-2-YL)-1,2-OXAZOL-3-YL]-2-[3-[1-(2-HYDROXYETHYL)PYRROLIDIN-1-IUM-1-YL]PROPYL]-4,6,7,8,8A,8B-HEXAHYDRO-3AH-PYRROLO[3,4-A]PYRROLIZINE-1,3-DIONE | n/a | |
| 135 | P00742_Y5H | Y5H | n/a | 54751670 | CHEMBL4294106 | 3-[(3AS,4R,5S,8AS,8BR)-4-[2-(5-CHLOROTHIOPHEN-2-YL)-1,3-OXAZOL-4-YL]-1,3-DIOXO-4,6,7,8,8A,8B-HEXAHYDRO-3AH-PYRROLO[3,4-A]PYRROLIZIN-2-YL]PROPYL-TRIMETHYL-AZANIUM | n/a | |
| 136 | P00742_YET | YET | n/a | 44249821 | CHEMBL551991 | 1-cyano-2-(2-methyl-1-benzofuran-5-yl)-3-[(3S)-2-oxo-1-(2-oxo-2-pyrrolidin-1-ylethyl)azepan-3-yl]guanidine | n/a | |
| 137 | P00742_Z34 | Z34 | n/a | 4322 | CHEMBL73193 | N-[2-[5-[AMINO(IMINO)METHYL]-2-HYDROXYPHENOXY]-3,5-DIFLUORO-6-[3-(4,5-DIHYDRO-1-METHYL-1H-IMIDAZOL-2-YL)PHENOXY]PYRIDIN-4-YL]-N-METHYLGLYCINE | n/a | |
| 138 | P00742_T87 | T87 | DB04107 | 9600423 | n/a | [(1-{2[(4-CARBAMIMIDOYL-PHENYLAMINO)-METHYL]-1-METHYL-1H-BENZOIMIDAZOL-5-YL}-CYCLOPROPYL)-PYRIDIN-2-YL-METHYLENEAMINOOXY]-ACETIC ACID ETHYL ESTER | n/a | Ki(nM) = 57.0 |
| 139 | P00742_DB00569 | no_lig_id | DB00569 | n/a | n/a | Fondaparinux | inhibitor | |
| 140 | P00742_CGU | CGU | DB03847 | n/a | n/a | gamma-carboxy-L-glutamic acid | inhibitor | |
| 141 | P00742_DB05713 | n/a | DB05713 | n/a | n/a | LY-517717 | inhibitor | |
| 142 | P00742_DB06406 | n/a | DB06406 | n/a | n/a | Idraparinux | inhibitor | |
| 143 | P00742_DB06635 | n/a | DB06635 | n/a | n/a | Otamixaban | inhibitor | |
| 144 | P00742_DB09075 | n/a | DB09075 | n/a | n/a | Edoxaban | inhibitor | Ki(nM) = 0.56 IC50(nM) = 3.4 |
| 145 | P00742_DB09332 | n/a | DB09332 | n/a | n/a | Kappadione | agonist | |
| 146 | P00742_DB12364 | n/a | DB12364 | n/a | n/a | Betrixaban | inhibitor | |
| 147 | P00742_7RF | 7RF | DB12598 | 4413 | CHEMBL273264 | Nafamostat | inhibitor |