Gene name: CFD
Protein name: Complement factor D
List of molecules and drugs that interact with protein P00746
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P00746_5W5 | 5W5 | n/a | 122164799 | CHEMBL4076148 | methyl 2-[[[(2~{S})-2-[[3-(trifluoromethyloxy)phenyl]carbamoyl]pyrrolidin-1-yl]carbonylamino]methyl]benzoate | n/a | |
| 2 | P00746_5WC | 5WC | n/a | 68283608 | CHEMBL3678914 | 1-[2-[(1~{R},3~{S},5~{R})-3-[[(1~{R})-1-(3-chloranyl-2-fluoranyl-phenyl)ethyl]carbamoyl]-2-azabicyclo[3.1.0]hexan-2-yl]-2-oxidanylidene-ethyl]pyrazolo[3,4-c]pyridine-3-carboxamide | n/a | |
| 3 | P00746_5WD | 5WD | n/a | 122164797 | CHEMBL4068335 | 3-[(2-aminocarbonyl-1~{H}-indol-5-yl)oxymethyl]benzoic acid | n/a | |
| 4 | P00746_8NQ | 8NQ | n/a | 86673884 | CHEMBL3683753 | 1-[2-[(1~{R},3~{S},5~{R})-3-[(6-bromanylpyridin-2-yl)carbamoyl]-2-azabicyclo[3.1.0]hexan-2-yl]-2-oxidanylidene-ethyl]indazole-3-carboxamide | n/a | |
| 5 | P00746_8RT | 8RT | n/a | 132471826 | CHEMBL4103449 | (2~{S})-~{N}1-(1-methylindol-3-yl)-~{N}2-[3-(trifluoromethyloxy)phenyl]pyrrolidine-1,2-dicarboxamide | n/a | |
| 6 | P00746_8RW | 8RW | n/a | 68284084 | CHEMBL3908849 | (2~{S})-~{N}1-(1-aminocarbonylindol-3-yl)-~{N}2-[3-(trifluoromethyloxy)phenyl]pyrrolidine-1,2-dicarboxamide | n/a | |
| 7 | P00746_8RZ | 8RZ | n/a | 71009649 | CHEMBL4065529 | (1~{R},3~{S},5~{R})-~{N}2-(1-aminocarbonylindol-3-yl)-~{N}3-[3-(trifluoromethyloxy)phenyl]-2-azabicyclo[3.1.0]hexane-2,3-dicarboxamide | n/a | |
| 8 | P00746_8S2 | 8S2 | n/a | 68284716 | CHEMBL3673825 | (2~{S},4~{S})-~{N}1-(1-aminocarbonylindol-3-yl)-4-azanyl-~{N}2-[3-(trifluoromethyloxy)phenyl]pyrrolidine-1,2-dicarboxamide | n/a | |
| 9 | P00746_8S5 | 8S5 | n/a | 68284602 | CHEMBL3668698 | (2~{S},4~{R})-~{N}1-(1-aminocarbonylindol-3-yl)-4-fluoranyl-~{N}2-[3-(trifluoromethyloxy)phenyl]pyrrolidine-1,2-dicarboxamide | n/a | |
| 10 | P00746_CIT | CIT | DB04272 | 311;19782904;88113319; | CHEMBL1261 | CITRIC ACID | n/a | |
| 11 | P00746_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 12 | P00746_DFP | DFP | DB04491 | 3072 | n/a | DIISOPROPYL PHOSPHONATE | n/a | |
| 13 | P00746_DIC | DIC | DB04459 | 1609 | CHEMBL24983 | 3,4-DICHLOROISOCOUMARIN | n/a | |
| 14 | P00746_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 15 | P00746_E7E | E7E | n/a | 134158400 | CHEMBL4170489 | ~{N}4-[3-(aminomethyl)phenyl]-1~{H}-indole-2,4-dicarboxamide | n/a | |
| 16 | P00746_E7H | E7H | n/a | n/a | n/a | 4-[[(5~{S},7~{R})-3-azanyl-1-adamantyl]carbonylamino]-1~{H}-indole-2-carboxamide | n/a | |
| 17 | P00746_E7W | E7W | n/a | 134158403 | CHEMBL4163988 | (1~{R},2~{S})-2-[[4-[[3-(aminomethyl)phenyl]amino]quinazolin-2-yl]amino]cyclohexane-1-carboxylic acid | n/a | |
| 18 | P00746_E82 | E82 | n/a | 134158405 | CHEMBL4161639 | 3-[3-(aminomethyl)phenyl]-~{N}-[(1~{S})-1,2,3,4-tetrahydronaphthalen-1-yl]benzamide | n/a | |
| 19 | P00746_E85 | E85 | n/a | 134158401 | CHEMBL4176772 | 3-[[3-[[3-(aminomethyl)phenyl]amino]-1~{H}-pyrazolo[3,4-d]pyrimidin-4-yl]amino]phenol | n/a | |
| 20 | P00746_E88 | E88 | n/a | 134158402 | CHEMBL4169870 | (2~{S})-2-[[4-[[3-(aminomethyl)phenyl]amino]quinazolin-2-yl]amino]-3-methyl-butanoic acid | n/a | |
| 21 | P00746_E8B | E8B | n/a | 134158404 | CHEMBL4170258 | ~{N}-[3-[3-(aminomethyl)phenyl]phenyl]-3-methyl-butanamide | n/a | |
| 22 | P00746_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 23 | P00746_J55 | J55 | n/a | 122177127 | CHEMBL3890777 | 1-(2-{(2S)-2-[(6-bromopyridin-2-yl)carbamoyl]-1,3-thiazolidin-3-yl}-2-oxoethyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide | n/a | |
| 24 | P00746_J56 | J56 | n/a | 122177128 | CHEMBL3924715 | (2S)-N-(6-bromopyridin-2-yl)-3-[(1H-indazol-1-yl)acetyl]-1,3-thiazolidine-2-carboxamide | n/a | |
| 25 | P00746_J6T | J6T | n/a | 117819668 | CHEMBL4548070 | 2-[2-[[3-[3-[(1~{S})-1-azanyl-2-oxidanyl-ethyl]phenyl]phenyl]methoxy]phenyl]ethanoic acid | n/a | |
| 26 | P00746_J7B | J7B | n/a | 90480064 | CHEMBL4475961 | 2-[2-[[3-[3-(aminomethyl)phenyl]phenyl]carbonylamino]phenyl]ethanoic acid | n/a | |
| 27 | P00746_M7O | M7O | n/a | 45267877 | CHEMBL561499 | 2-[(phenylmethyl)carbamoylamino]benzoic acid | n/a | |
| 28 | P00746_O | O | n/a | 962;22247451; | CHEMBL1098659 | OXYGEN ATOM | n/a | |
| 29 | P00746_QIE | QIE | n/a | 165416437 | CHEMBL5220109 | N-(6-bromopyridin-2-yl)-1-[(3-cyanophenyl)acetyl]-L-prolinamide | n/a | |
| 30 | P00746_QJS | QJS | n/a | 7395803 | CHEMBL4085766 | 5-fluoranyl-3-[[(1~{S},2~{S})-2-phenylcyclopropyl]carbonylamino]-1~{H}-indole-2-carboxylic acid | n/a | |
| 31 | P00746_R7X | R7X | n/a | 165416441 | CHEMBL5218908 | 1-[(3-acetylphenyl)acetyl]-N-(6-bromopyridin-2-yl)-L-prolinamide | n/a | |
| 32 | P00746_S7X | S7X | n/a | 165416442 | CHEMBL5219728 | 1-{2-[(2S)-2-{[(3-chloro-2-fluorophenyl)methyl]carbamoyl}pyrrolidin-1-yl]-2-oxoethyl}-1H-indazole-3-carboxamide | n/a | |
| 33 | P00746_SIN | SIN | DB00139 | 1110;21952380; | CHEMBL576 | SUCCINIC ACID | n/a | |
| 34 | P00746_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 35 | P00746_SOA | SOA | DB03058 | 21439 | CHEMBL1235999 | ISATOIC ANHYDRIDE | n/a |