Gene name: ampC
Protein name: Beta-lactamase (EC 3.5.2.6)
List of molecules and drugs that interact with protein P00811
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P00811_0N3 | 0N3 | n/a | 71549310 | n/a | 3-({[(dihydroxyboranyl)methyl]sulfamoyl}methyl)benzoic acid | n/a | |
| 2 | P00811_0N4 | 0N4 | n/a | 71549452 | CHEMBL3613795 | [({[4-(1H-tetrazol-5-yl)phenyl]sulfonyl}amino)methyl]boronic acid | n/a | |
| 3 | P00811_0NA | 0NA | n/a | 71519580 | CHEMBL4094945 | [({[6-(1H-tetrazol-5-yl)pyridin-3-yl]sulfonyl}amino)methyl]boronic acid | n/a | |
| 4 | P00811_0NB | 0NB | n/a | 60182328 | n/a | [({[3-chloro-4-(1H-tetrazol-5-yl)phenyl]sulfonyl}amino)methyl]boronic acid | n/a | |
| 5 | P00811_0ND | 0ND | n/a | 60182330 | n/a | [({[2-chloro-4-(1H-tetrazol-5-yl)phenyl]sulfonyl}amino)methyl]boronic acid | n/a | |
| 6 | P00811_0NE | 0NE | n/a | 71549453 | CHEMBL3613796 | [({[4-(1H-tetrazol-5-yl)-2-(trifluoromethyl)phenyl]sulfonyl}amino)methyl]boronic acid | n/a | |
| 7 | P00811_0NG | 0NG | n/a | 71549315 | n/a | ({[(chloromethyl)sulfonyl]amino}methyl)boronic acid | n/a | |
| 8 | P00811_105 | 105 | DB00713 | 2815 | CHEMBL324688 | N-[5-METHYL-3-O-TOLYL-ISOXAZOLE-4-CARBOXYLIC ACID AMIDE] BORONIC ACID | n/a | |
| 9 | P00811_18U | 18U | n/a | 73659121 | CHEMBL3287788 | 3-[(4-carboxybenzyl)sulfamoyl]thiophene-2-carboxylic acid | n/a | |
| 10 | P00811_1MU | 1MU | n/a | 73659122 | CHEMBL3287789 | 3-{[2-(4-carboxyphenyl)ethyl]sulfamoyl}thiophene-2-carboxylic acid | n/a | |
| 11 | P00811_1MW | 1MW | n/a | 73659123 | CHEMBL3287790 | 3-{[3-(4-carboxyphenyl)propyl]sulfamoyl}thiophene-2-carboxylic acid | n/a | |
| 12 | P00811_1S6 | 1S6 | n/a | 137347989 | n/a | (2R,4S)-5,5-dimethyl-2-[(1R)-1-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-2-oxoethyl]-1,3-thiazolidine-4-carb oxylic acid | n/a | |
| 13 | P00811_1S7 | 1S7 | n/a | 137347990 | n/a | (2R)-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid | n/a | |
| 14 | P00811_1U1 | 1U1 | n/a | 25219388 | n/a | 5-chloro-3-sulfamoylthiophene-2-carboxylic acid | n/a | |
| 15 | P00811_1U3 | 1U3 | n/a | 426788 | CHEMBL1741573 | N-{[3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}glycine | n/a | |
| 16 | P00811_1U5 | 1U5 | n/a | 181870 | n/a | (1R,4S)-4,7,7-trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carboxylic acid | n/a | |
| 17 | P00811_1U6 | 1U6 | n/a | 78890 | CHEMBL2136061 | 1,3-diethyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione | n/a | |
| 18 | P00811_1U7 | 1U7 | n/a | 11865391 | n/a | (4R,4aS,8aS)-4-phenyldecahydroquinolin-4-ol | n/a | |
| 19 | P00811_23C | 23C | DB06922 | 16752640 | CHEMBL405886 | 2-[(1R)-1-carboxy-2-naphthalen-1-ylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid | n/a | Ki(nM) = 5000.0 |
| 20 | P00811_25N | 25N | n/a | 11470330 | n/a | (3,5-di-tert-butylphenyl)boronic acid | n/a | |
| 21 | P00811_2TV | 2TV | n/a | 137348083 | n/a | (2R,5Z)-5-[(acetyloxy)methylidene]-2-[(1R)-1-(formylamino)-2-oxoethyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid | n/a | |
| 22 | P00811_2UZ | 2UZ | n/a | 73819560 | n/a | (2R)-2-[(R)-amino(carboxy)methyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid | n/a | |
| 23 | P00811_2V0 | 2V0 | n/a | 73819559 | n/a | (2R)-2-[(R)-amino(carboxy)methyl]-5-methyl-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid | n/a | |
| 24 | P00811_3GV | 3GV | DB07057 | 756618 | n/a | (3S)-1-(2-hydroxyphenyl)-5-oxopyrrolidine-3-carboxylic acid | n/a | |
| 25 | P00811_4A1 | 4A1 | n/a | 16770253 | n/a | 2-[(propylsulfonyl)amino]benzoic acid | n/a | |
| 26 | P00811_4A3 | 4A3 | n/a | 137566 | CHEMBL1462 | 4-AMINO-3-HYDROXYBENZOIC ACID | n/a | |
| 27 | P00811_4CB | 4CB | DB03140 | 312183 | CHEMBL82324 | 4-CARBOXYPHENYLBORONIC ACID | n/a | Ki(nM) = 2900.0 |
| 28 | P00811_4MB | 4MB | DB07114 | 250653 | CHEMBL339996 | 4-[(METHYLSULFONYL)AMINO]BENZOIC ACID | n/a | Ki(nM) = 1.0E7 |
| 29 | P00811_APB | APB | DB01896 | 92269 | CHEMBL20852 | M-AMINOPHENYLBORONIC ACID | n/a | Ki(nM) = 7300.0 |
| 30 | P00811_AXL | AXL | DB03658 | 5287717 | n/a | 2-{1-[2-AMINO-2-(4-HYDROXY-PHENYL)-ACETYLAMINO]-2-OXO-ETHYL}-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID | n/a | |
| 31 | P00811_BDB | BDB | DB02627 | 2734608 | CHEMBL109227 | 4,4'-BIPHENYLDIBORONIC ACID | n/a | Ki(nM) = 200.0 |
| 32 | P00811_BSF | BSF | n/a | 49837085 | CHEMBL1231476 | {[(benzylsulfonyl)amino]methyl}boronic acid | n/a | |
| 33 | P00811_BSG | BSG | n/a | 49837191 | CHEMBL1231477 | 4-({[(dihydroxyboranyl)methyl]sulfamoyl}methyl)benzoic acid | n/a | |
| 34 | P00811_BSH | BSH | n/a | 49837194 | CHEMBL1231478 | 3-[(2R)-2-[(benzylsulfonyl)amino]-2-(dihydroxyboranyl)ethyl]benzoic acid | n/a | |
| 35 | P00811_BZB | BZB | DB04360 | 2359 | CHEMBL34964 | BENZO[B]THIOPHENE-2-BORONIC ACID | n/a | Ki(nM) = 27.0 IC50(nM) = 150.0 |
| 36 | P00811_C21 | C21 | n/a | 10700 | CHEMBL1222314 | THIOPHENE-2-CARBOXYLIC ACID | n/a | |
| 37 | P00811_C8V | C8V | n/a | 137349066 | n/a | (2S,5R)-1-formyl-N'-[(3R)-piperidine-3-carbonyl]-5-[(sulfooxy)amino]piperidine-2-carbohydrazide | n/a | |
| 38 | P00811_C9P | C9P | DB07541 | 46890069 | CHEMBL1084081 | 4-(dihydroxyboranyl)-2-({[4-(phenylsulfonyl)thiophen-2-yl]sulfonyl}amino)benzoic acid | n/a | |
| 39 | P00811_CAZ | CAZ | DB03530 | 9600404 | n/a | ACYLATED CEFTAZIDIME | n/a | |
| 40 | P00811_CB4 | CB4 | DB04035 | 5849540 | CHEMBL1231661 | PINACOL[[2-AMINO-ALPHA-(1-CARBOXY-1-METHYLETHOXYIMINO)-4-THIAZOLEACETYL]AMINO]METHANEBORONATE | n/a | |
| 41 | P00811_CEF | CEF | DB08375 | 131704308 | n/a | CEFOTAXIME, C3' cleaved, open, bound form | n/a | |
| 42 | P00811_CEO | CEO | n/a | 5287907 | n/a | 5-METHYLENE-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID | n/a | |
| 43 | P00811_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 44 | P00811_CLS | CLS | DB00456 | 6024 | CHEMBL617 | CEPHALOTHIN | potentiator | |
| 45 | P00811_CTB | CTB | DB02094 | 2671 | CHEMBL320049 | N-2-THIOPHEN-2-YL-ACETAMIDE BORONIC ACID | n/a | Ki(nM) = 320.0 |
| 46 | P00811_CVB | CVB | DB02503 | 5288001 | CHEMBL139928 | 4-(CARBOXYVIN-2-YL)PHENYLBORONIC ACID | n/a | Ki(nM) = 4200.0 |
| 47 | P00811_CXU | CXU | n/a | 137349139 | n/a | CLOXACILLIN (OPEN FORM) | n/a | |
| 48 | P00811_DK2 | DK2 | DB07663 | 7013169 | CHEMBL264702 | 2-[(1R)-1-CARBOXY-2-(4-HYDROXYPHENYL)ETHYL]-1,3-DIOXOISOINDOLINE-5-CARBOXYLIC ACID | n/a | |
| 49 | P00811_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 50 | P00811_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 51 | P00811_EPE | EPE | DB16872 | 23830;23831;3275884; | CHEMBL1232545 | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | n/a | |
| 52 | P00811_ETP | ETP | DB02858 | 1475 | CHEMBL113381 | 3-(4-BENZENESULFONYL-THIOPHENE-2-SULFONYLAMINO)-PHENYLBORONIC ACID | n/a | Ki(nM) = 80.0 |
| 53 | P00811_F12 | F12 | n/a | 1477332 | CHEMBL1213612 | 2-(ACETYLAMINO)THIOPHENE-3-CARBOXYLIC ACID | n/a | |
| 54 | P00811_G14 | G14 | DB07803 | 2738139 | CHEMBL1232889 | 2-phenyl-1H-imidazole-4-carboxylic acid | n/a | |
| 55 | P00811_GF1 | GF1 | DB07823 | 1933963 | n/a | (2S)-2-[(3aR,4R,7S,7aS)-1,3-dioxooctahydro-2H-4,7-methanoisoindol-2-yl]propanoic acid | n/a | |
| 56 | P00811_GF4 | GF4 | DB07824 | 5305969 | CHEMBL1213368 | 4-ethyl-5-methyl-2-(1H-tetrazol-5-yl)-1,2-dihydro-3H-pyrazol-3-one | n/a | |
| 57 | P00811_GF7 | GF7 | DB07825 | 2376771 | n/a | (3S)-1-(4-acetylphenyl)-5-oxopyrrolidine-3-carboxylic acid | n/a | |
| 58 | P00811_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 59 | P00811_GTC | GTC | DB07850 | 976666 | n/a | (1R,2S)-2-(5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)cyclohexanecarboxylic acid | n/a | |
| 60 | P00811_GV9 | GV9 | n/a | 2807579 | n/a | 3-(acetylamino)thiophene-2-carboxylic acid | n/a | |
| 61 | P00811_H7A | H7A | n/a | 134613161 | n/a | 4-{[(4R)-6-fluoro-3,4-dihydro-2H-1-benzopyran-4-yl]sulfamoyl}-2,5-dimethylfuran-3-carboxylic acid | n/a | |
| 62 | P00811_H7D | H7D | n/a | 134613162 | n/a | (1R,2S)-2-{[(pyrrolidin-1-yl)sulfonyl]amino}cyclooctane-1-carboxylic acid | n/a | |
| 63 | P00811_H7G | H7G | n/a | 134613160 | n/a | (3-{[(3-chloro-2-hydroxyphenyl)sulfonyl]amino}phenyl)acetic acid | n/a | |
| 64 | P00811_H7M | H7M | n/a | 132373998 | n/a | 3-chloro-2-hydroxy-N-{2-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]phenyl}benzene-1-sulfonamide | n/a | |
| 65 | P00811_HTC | HTC | DB07927 | 657106 | CHEMBL1222313 | 3-{[(4-CARBOXY-2-HYDROXYANILINE]SULFONYL}THIOPHENE-2-CARBOXYLIC ACID | n/a | Ki(nM) = 1000.0 |
| 66 | P00811_IM2 | IM2 | n/a | 5288621 | n/a | (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid | n/a | |
| 67 | P00811_K | K | n/a | 813 | CHEMBL1233793 | POTASSIUM ION | n/a | |
| 68 | P00811_K9K | K9K | n/a | n/a | n/a | (10aR)-2-(((1r,4R)-4-((2-aminoethyl)amino)cyclohexyl)methyl)-6-carboxy-4-hydroxy-4,10a-dihydro-10H-benzo[5,6][1,2]oxaborinino[2,3-b][1,4,2]oxazaborol-4-uide | n/a | |
| 69 | P00811_KCP | KCP | DB02247 | 5288660 | n/a | 2-[CARBOXY-(2-THIOPHEN-2-YL-ACETYLAMINO)-METHYL]-5-METHYL-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID | n/a | |
| 70 | P00811_KJK | KJK | DB16338 | n/a | CHEMBL4463697 | (3~{R})-3-[2-[4-(2-azanylethylamino)cyclohexyl]ethanoylamino]-2-oxidanyl-3,4-dihydro-1,2-benzoxaborinine-8-carboxylic acid | n/a | |
| 71 | P00811_KL8 | KL8 | n/a | 145998273 | n/a | (3~{S})-2,2-bis(oxidanyl)-3-(phenylmethylsulfanyl)-3,4-dihydro-1,2-benzoxaborinin-2-ium-8-carboxylic acid | n/a | |
| 72 | P00811_LOR | LOR | DB04293 | n/a | n/a | LORACABEF (Open form) | n/a | |
| 73 | P00811_M9W | M9W | n/a | 154815554 | n/a | Enmetazobactam derived trans-enamine adduct | n/a | |
| 74 | P00811_MES | MES | DB03814 | 78165;4478249; | CHEMBL1234276 | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | n/a | |
| 75 | P00811_MK7 | MK7 | n/a | 137349751 | n/a | (2S,5R)-1-formyl-N-(piperidin-4-yl)-5-[(sulfooxy)amino]piperidine-2-carboxamide | n/a | |
| 76 | P00811_MOX | MOX | DB02588 | 131704211 | n/a | (2R)-2-[(1R)-1-{[(2S)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino}-1-methoxy-2-oxoethyl]-5-methylidene-5,6-dihydro-2H-1,3-oxazine-4-carboxylic acid | n/a | |
| 77 | P00811_MPD | MPD | DB03564 | 5288834 | n/a | (4S)-2-METHYL-2,4-PENTANEDIOL | n/a | |
| 78 | P00811_MXG | MXG | n/a | 6323425 | n/a | 2-(1-{2-[4-(2-ACETYLAMINO-PROPIONYLAMINO)-4-CARBOXY-BUTYRYLAMINO]-6-AMINO-HEXANOYLAMINO}-2-OXO-ETHYL)-5-METHYLENE-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID | n/a | |
| 79 | P00811_N95 | N95 | n/a | 46738749 | CHEMBL5274236 | [1-(6-chloropyrimidin-4-yl)-1H-pyrazol-4-yl]boronic acid | n/a | |
| 80 | P00811_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 81 | P00811_NL9 | NL9 | n/a | 46738677 | n/a | [1-(3-chlorophenyl)-1H-pyrazol-4-yl]boronic acid | n/a | |
| 82 | P00811_NPB | NPB | DB02797 | 1677 | CHEMBL20945 | 3-NITROPHENYLBORONIC ACID | n/a | |
| 83 | P00811_NST | NST | DB08306 | 657105 | n/a | 3-{[(3-NITROANILINE]SULFONYL}THIOPHENE-2-CARBOXYLIC ACID | n/a | |
| 84 | P00811_NXL | NXL | n/a | 132451794 | n/a | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide | n/a | |
| 85 | P00811_NZ2 | NZ2 | n/a | 40554647 | n/a | N-(methylsulfonyl)-N-phenyl-L-alanine | n/a | |
| 86 | P00811_NZ3 | NZ3 | n/a | 40554723 | n/a | N-(methylsulfonyl)-N-phenyl-D-alanine | n/a | |
| 87 | P00811_NZ9 | NZ9 | n/a | 16227156 | n/a | 3-(cyclopropylsulfamoyl)thiophene-2-carboxylic acid | n/a | |
| 88 | P00811_OK3 | OK3 | n/a | 121488102 | CHEMBL4461260 | (4~{R})-4-[[4-(aminomethyl)phenyl]carbonylamino]-3,3-bis(oxidanyl)-2-oxa-3-boranuidabicyclo[4.4.0]deca-1(10),6,8-triene-10-carboxylic acid | n/a | |
| 89 | P00811_OP0 | OP0 | n/a | 137349848 | n/a | (2S,5R)-N-(2-aminoethoxy)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide | n/a | |
| 90 | P00811_OX6 | OX6 | DB08336 | 46937140 | n/a | TERT-BUTYL [(1R)-2-METHYL-1-(1,3,4-OXADIAZOL-2-YL)PROPYL]CARBAMATE | n/a | |
| 91 | P00811_OX7 | OX7 | DB08337 | 46937141 | n/a | TERT-BUTYL [(1S)-2-METHYL-1-(1,3,4-OXADIAZOL-2-YL)PROPYL]CARBAMATE | n/a | |
| 92 | P00811_PCN | PCN | DB03437 | 9600418 | n/a | 2-{1-[2-(2-AMINO-THIAZOL-4-YL)-2-METHOXYIMINO-ACETYLAMINO]-2-OXO-ETHYL}-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID | n/a | |
| 93 | P00811_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 94 | P00811_PGE | PGE | DB02327 | 8172 | CHEMBL1235259 | TRIETHYLENE GLYCOL | n/a | |
| 95 | P00811_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 96 | P00811_SM2 | SM2 | DB08551 | 5289377 | CHEMBL257468 | (1R)-1-(2-THIENYLACETYLAMINO)-1-(3-CARBOXYPHENYL)METHYLBORONIC ACID | n/a | |
| 97 | P00811_SM3 | SM3 | DB08552 | 5289378 | CHEMBL404155 | (1R)-1-(2-THIENYLACETYLAMINO)-1-PHENYLMETHYLBORONIC ACID | n/a | |
| 98 | P00811_SM4 | SM4 | n/a | 24873522 | CHEMBL429972 | (1R)-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-1-(3-(2-CARBOXYVINYL)-PHENYL) METHYLBORONIC ACID | n/a | |
| 99 | P00811_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 100 | P00811_THN | THN | DB08623 | 46937164 | n/a | 2-[CARBOXY-(2-THIOPHEN-2-YL-ACETYLAMINO)-METHYL]-5-METHYLENE-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID | n/a | |
| 101 | P00811_VA1 | VA1 | n/a | 23655305 | CHEMBL235073 | {5-[(DIFORMYLAMINO)METHYL]-1-BENZOTHIEN-2-YL}BORONIC ACID | n/a | |
| 102 | P00811_WH6 | WH6 | DB08731 | 24764434 | n/a | 2-[(1R)-2-carboxy-1-(naphthalen-1-ylmethyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid | n/a | |
| 103 | P00811_ZB6 | ZB6 | n/a | 762560 | n/a | (2R,6R)-6-methyl-1-(3-sulfanylpropanoyl)piperidine-2-carboxylic acid | n/a | |
| 104 | P00811_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 105 | P00811_STC | STC | DB08573 | 446853 | CHEMBL372227 | 3-[(4-CHLOROANILINO)SULFONYL]THIOPHENE-2-CARBOXYLIC ACID | n/a | Ki(nM) = 26000.0 |