Gene name: CA1
Protein name: Carbonic anhydrase 1
List of molecules and drugs that interact with protein P00915
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P00915_3TV | 3TV | n/a | 71584199 | CHEMBL2333418 | 2,3,5,6-tetrafluoro-4-(propylsulfanyl)benzenesulfonamide | n/a | |
| 2 | P00915_3UF | 3UF | n/a | 4269754 | CHEMBL106848 | 4-[(2-hydroxyethyl)sulfanyl]benzenesulfonamide | n/a | |
| 3 | P00915_3UG | 3UG | n/a | 91809487 | CHEMBL3797893 | 2,3,5,6-tetrafluoro-4-(piperidin-1-yl)benzenesulfonamide | n/a | |
| 4 | P00915_7TI | 7TI | DB11389 | 43231 | CHEMBL1474129 | 4-azanyl-6-[1,2,2-tris(chloranyl)ethenyl]benzene-1,3-disulfonamide | n/a | |
| 5 | P00915_84Z | 84Z | n/a | 126508404 | n/a | methyl 4-chloranyl-2-(phenylsulfonyl)-5-sulfamoyl-benzoate | n/a | |
| 6 | P00915_949 | 949 | DB12399 | 9841854 | CHEMBL166863 | 4-[3-(3-fluorophenyl)-5,5-dimethyl-4-oxidanylidene-furan-2-yl]benzenesulfonamide | inhibitor | |
| 7 | P00915_AAS | AAS | n/a | 16684345 | n/a | 3-ACTOXYMERCURI-4-AMINOBENZENESULFONAMIDE | n/a | |
| 8 | P00915_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 9 | P00915_AUC | AUC | n/a | n/a | n/a | GOLD (I) CYANIDE ION | n/a | |
| 10 | P00915_AZM | AZM | DB00819 | 1986 | CHEMBL20 | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE | inhibitor | Ki(nM) = 0.25 IC50(nM) = 0.9957 Kd(nM) = 290.0 |
| 11 | P00915_B30 | B30 | n/a | 11840924;15978001; | n/a | {2,2'-[(2-{[4-(AMINOSULFONYL)BENZOYL]AMINO}ETHYL)IMINO]DIACETATO(2-)-KAPPAO}COPPER | n/a | |
| 12 | P00915_BCT | BCT | n/a | 769;22647601; | n/a | BICARBONATE ION | n/a | |
| 13 | P00915_BZW | BZW | n/a | 134158397 | CHEMBL4166970 | 4-[(3~{S})-4-ethanoyl-3-(phenylmethyl)piperazin-1-yl]carbonylbenzenesulfonamide | n/a | |
| 14 | P00915_CJK | CJK | n/a | 134817796 | CHEMBL4294703 | 1-[(4-methylphenyl)methyl]-3-(2-oxidanyl-5-sulfamoyl-phenyl)urea | n/a | |
| 15 | P00915_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 16 | P00915_D3B | D3B | n/a | 134817797 | CHEMBL4286620 | 1-(2,5-dimethylphenyl)-3-(2-oxidanyl-5-sulfamoyl-phenyl)urea | n/a | |
| 17 | P00915_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 18 | P00915_E7I | E7I | n/a | 101870860 | n/a | benzoselenoate | n/a | |
| 19 | P00915_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 20 | P00915_EON | EON | n/a | 134817798 | CHEMBL4282828 | 1-(2-methoxyphenyl)-3-(2-oxidanyl-5-sulfamoyl-phenyl)urea | n/a | |
| 21 | P00915_FLB | FLB | n/a | 70789750 | n/a | 1-(2-ethoxyethoxy)-3,5-bis(trifluoromethyl)benzene | n/a | |
| 22 | P00915_FO9 | FO9 | n/a | n/a | n/a | famotidine | n/a | |
| 23 | P00915_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 24 | P00915_GXE | GXE | n/a | 69530 | CHEMBL5186653 | benzeneselenol | n/a | |
| 25 | P00915_GZE | GZE | n/a | 139593608 | CHEMBL4465167 | [4-[[4-chloranyl-3-(trifluoromethyl)phenyl]carbamoylamino]phenyl] sulfamate | n/a | |
| 26 | P00915_GZH | GZH | n/a | 60446869 | CHEMBL4457039 | 1-[4-chloranyl-3-(trifluoromethyl)phenyl]-3-[2-(4-sulfamoylphenyl)ethyl]urea | n/a | |
| 27 | P00915_H2S | H2S | n/a | 402;18779926; | CHEMBL1200739 | HYDROSULFURIC ACID | n/a | |
| 28 | P00915_HG | HG | n/a | 26623 | n/a | MERCURY (II) ION | n/a | |
| 29 | P00915_HIS | HIS | DB00117 | 5288559;5460943;86580368; | n/a | HISTIDINE | n/a | |
| 30 | P00915_IOD | IOD | n/a | 30165 | n/a | IODIDE ION | n/a | |
| 31 | P00915_IWE | IWE | DB08961 | 2273 | CHEMBL1097235 | Azosemide | n/a | |
| 32 | P00915_LVW | LVW | n/a | 155804454 | n/a | (2~{R})-1-prop-2-enoxy-3-selanyl-propan-2-ol | n/a | |
| 33 | P00915_M25 | M25 | DB08155 | 745994 | n/a | N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE | inhibitor | |
| 34 | P00915_M28 | M28 | DB08156 | 3161908 | CHEMBL451332 | 3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID | inhibitor | Ki(nM) = 6690.0 |
| 35 | P00915_M29 | M29 | DB08157 | 16122582 | n/a | ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE | inhibitor | |
| 36 | P00915_MZM | MZM | n/a | 5353756 | n/a | N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamide | n/a | |
| 37 | P00915_N19 | N19 | n/a | 134817795 | CHEMBL4160707 | 4-[(3~{R})-3-(phenylmethyl)piperazin-1-yl]carbonylbenzenesulfonamide | n/a | |
| 38 | P00915_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 39 | P00915_O4Z | O4Z | n/a | 154585756 | n/a | 1-[2-[(2-fluorophenyl)methylamino]ethyl]-3-(4-sulfamoylphenyl)urea | n/a | |
| 40 | P00915_O55 | O55 | n/a | 154585757 | n/a | 1-[2-[(4-bromanyl-2-oxidanyl-phenyl)methylamino]ethyl]-3-(4-sulfamoylphenyl)urea | n/a | |
| 41 | P00915_O5H | O5H | n/a | 154585759 | n/a | 1-[2-[(phenylmethyl)amino]ethyl]-3-(3-sulfamoylphenyl)urea | n/a | |
| 42 | P00915_O5K | O5K | n/a | 154585758 | n/a | 1-[2-[(4-fluorophenyl)methylamino]ethyl]-3-(4-sulfamoylphenyl)urea | n/a | |
| 43 | P00915_O5N | O5N | n/a | 154585760 | n/a | 1-[2-[(2-fluorophenyl)methylamino]ethyl]-3-(3-sulfamoylphenyl)urea | n/a | |
| 44 | P00915_O5T | O5T | n/a | 154585761 | n/a | 1-[2-[(4-bromanyl-2-oxidanyl-phenyl)methylamino]ethyl]-3-(3-sulfamoylphenyl)urea | n/a | |
| 45 | P00915_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 46 | P00915_PPF | PPF | DB00529 | 3415 | CHEMBL666 | PHOSPHONOFORMIC ACID | n/a | |
| 47 | P00915_TOR | TOR | DB00273 | 5284627 | CHEMBL220492 | [(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate | inhibitor | Ki(nM) = 56.0 IC50(nM) = 250.0 |
| 48 | P00915_TRS | TRS | DB03754 | 3777159;88088752;152743085; | n/a | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | n/a | |
| 49 | P00915_V14 | V14 | n/a | 73774785 | CHEMBL3359181 | 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide | n/a | |
| 50 | P00915_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 51 | P00915_DB00232 | n/a | DB00232 | n/a | n/a | Methyclothiazide | inhibitor | |
| 52 | P00915_DB00310 | n/a | DB00310 | n/a | n/a | Chlorthalidone | inhibitor | Ki(nM) = 348.0 IC50(nM) = 260.0 |
| 53 | P00915_EZL | EZL | DB00311 | 3295 | CHEMBL18 | Ethoxzolamide | inhibitor | Ki(nM) = 25.0 IC50(nM) = 8.0 Kd(nM) = 14.0 |
| 54 | P00915_DB00381 | n/a | DB00381 | n/a | n/a | Amlodipine | inhibitor | |
| 55 | P00915_DB00423 | n/a | DB00423 | n/a | n/a | Methocarbamol | inhibitor | |
| 56 | P00915_DB00436 | n/a | DB00436 | n/a | n/a | Bendroflumethiazide | inhibitor | |
| 57 | P00915_DB00562 | n/a | DB00562 | n/a | n/a | Benzthiazide | inhibitor | |
| 58 | P00915_DB00606 | n/a | DB00606 | n/a | n/a | Cyclothiazide | inhibitor | |
| 59 | P00915_DB00703 | n/a | DB00703 | n/a | n/a | Methazolamide | inhibitor | |
| 60 | P00915_HFZ | HFZ | DB00774 | 3647 | CHEMBL1763 | Hydroflumethiazide | inhibitor | Ki(nM) = 2840.0 |
| 61 | P00915_ETS | ETS | DB00869 | 5284549 | CHEMBL218490 | Dorzolamide | inhibitor | Ki(nM) = 500.0 IC50(nM) = 1583.63 |
| 62 | P00915_DB00880 | n/a | DB00880 | n/a | n/a | Chlorothiazide | inhibitor | |
| 63 | P00915_ZON | ZON | DB00909 | 5734;11967800; | CHEMBL750 | Zonisamide | inhibitor | Ki(nM) = 56.0 IC50(nM) = 35.0 |
| 64 | P00915_DB01021 | n/a | DB01021 | n/a | n/a | Trichlormethiazide | inhibitor | Ki(nM) = 345.0 |
| 65 | P00915_DB01031 | n/a | DB01031 | n/a | n/a | Ethinamate | inhibitor | |
| 66 | P00915_20J | 20J | DB01119 | 3019 | CHEMBL181 | Diazoxide | n/a | |
| 67 | P00915_I7A | I7A | DB01144 | 3038 | CHEMBL17 | Diclofenamide | inhibitor | Ki(nM) = 25.0 IC50(nM) = 38.0 |
| 68 | P00915_BZ1 | BZ1 | DB01194 | 68844 | CHEMBL220491 | Brinzolamide | inhibitor | Ki(nM) = 3.0 |
| 69 | P00915_DB01325 | n/a | DB01325 | n/a | n/a | Quinethazone | inhibitor | Ki(nM) = 35000.0 |
| 70 | P00915_REF | REF | DB08846 | 5281855 | CHEMBL6246 | Ellagic acid | inhibitor | |
| 71 | P00915_DB09460 | n/a | DB09460 | n/a | n/a | Sodium carbonate | inhibitor | |
| 72 | P00915_DB09472 | n/a | DB09472 | n/a | n/a | Sodium sulfate | inhibitor |