P01116 RASK_HUMAN
Gene name: KRAS
Protein name: GTPase KRas (EC

List of molecules and drugs that interact with protein P01116

#	DrugDomain Data	PBD ligand	DrugBank Accession	PubChem	ChEMBL	Name	Drug action	Affinity data
1	P01116_05C	05C	n/a	162371030	n/a	7-(8-methylnaphthalen-1-yl)-4-[(2~{R})-2-methylpiperazin-1-yl]-2-[[(2~{S})-1-methylpyrrolidin-2-yl]methoxy]-6,8-dihydro-5~{H}-pyrido[3,4-d]pyrimidine	n/a
2	P01116_05F	05F	n/a	162371031	n/a	4-[(1~{R},5~{S})-3,8-diazabicyclo[3.2.1]octan-8-yl]-7-(8-methylnaphthalen-1-yl)-2-[[(2~{S})-1-methylpyrrolidin-2-yl]methoxy]-6,8-dihydro-5~{H}-pyrido[3,4-d]pyrimidine	n/a
3	P01116_05I	05I	n/a	162371032	n/a	4-[(1~{S},5~{R})-3,8-diazabicyclo[3.2.1]octan-3-yl]-7-(8-methylnaphthalen-1-yl)-2-[[(2~{S})-1-methylpyrrolidin-2-yl]methoxy]-6,8-dihydro-5~{H}-pyrido[3,4-d]pyrimidine	n/a
4	P01116_0QR	0QR	n/a	56965955	CHEMBL2086793	N-(6-aminopyridin-2-yl)-4-fluorobenzenesulfonamide	n/a
5	P01116_0QV	0QV	n/a	56965954	CHEMBL2086792	(4-hydroxypiperidin-1-yl)(1H-indol-3-yl)methanethione	n/a
6	P01116_0QW	0QW	n/a	551134	CHEMBL1606182	(2-hydroxyphenyl)(pyrrolidin-1-yl)methanethione	n/a
7	P01116_0QX	0QX	n/a	56965953	CHEMBL2086791	2-(1H-indol-3-ylmethyl)-1H-imidazo[4,5-c]pyridine	n/a
8	P01116_0QY	0QY	n/a	56965956	CHEMBL2086796	N-[2-(1H-indol-3-ylmethyl)-1H-benzimidazol-5-yl]-L-prolinamide	n/a
9	P01116_17F	17F	DB18573	6438639;44825325;	CHEMBL4165044	O-[(S)-({(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl}oxy)(hydroxy)phosphoryl]-L-serine	n/a
10	P01116_20G	20G	n/a	71815954	CHEMBL4303198	N-{1-[(2,4-dichlorophenoxy)acetyl]piperidin-4-yl}-4-sulfanylbutanamide	n/a
11	P01116_20H	20H	n/a	71815953	n/a	1-[(2,4-dichlorophenoxy)acetyl]-N-(2-sulfanylethyl)piperidine-4-carboxamide	n/a
12	P01116_21C	21C	n/a	137348015	n/a	N-{1-[N-(4,5-dichloro-2-hydroxyphenyl)glycyl]piperidin-4-yl}ethanesulfonamide	n/a
13	P01116_21F	21F	n/a	137348016	n/a	N-{1-[N-(4-chloro-5-iodo-2-methoxyphenyl)glycyl]piperidin-4-yl}ethanesulfonamide	n/a
14	P01116_21J	21J	n/a	137348017	n/a	N-(1-{[(5,7-dichloro-2,2-dimethyl-1,3-benzodioxol-4-yl)oxy]acetyl}piperidin-4-yl)ethanesulfonamide	n/a
15	P01116_21K	21K	n/a	137348018	n/a	N-{1-[N-(2,4-dichlorophenyl)glycyl]piperidin-4-yl}ethanesulfonamide	n/a
16	P01116_21M	21M	n/a	108565292	n/a	N-{1-[(2,4-dichlorophenoxy)acetyl]piperidin-4-yl}ethanesulfonamide	n/a
17	P01116_21R	21R	n/a	137348019	n/a	N-{1-[N-(4,5-dichloro-2-ethylphenyl)glycyl]piperidin-4-yl}ethanesulfonamide	n/a
18	P01116_21S	21S	n/a	137348020	n/a	N-{1-[N-(5,7-dichloro-2,1,3-benzothiadiazol-4-yl)glycyl]piperidin-4-yl}ethanesulfonamide	n/a
19	P01116_21Y	21Y	n/a	137348021	n/a	1-(4-{[(4,5-dichloro-2-methoxyphenyl)amino]acetyl}piperazin-1-yl)propan-1-one	n/a
20	P01116_22C	22C	n/a	110817114	n/a	1-{4-[(2,4-dichlorophenoxy)acetyl]piperazin-1-yl}propan-1-one	n/a
21	P01116_2XE	2XE	n/a	66049	CHEMBL278240	4-bromobenzenethiol	n/a
22	P01116_2XG	2XG	n/a	2778378	n/a	3,4-difluorobenzenethiol	n/a
23	P01116_2XH	2XH	n/a	68259	CHEMBL4094874	naphthalene-1-thiol	n/a
24	P01116_2XO	2XO	n/a	95983	CHEMBL2358377	1H-benzimidazol-2-ylmethanethiol	n/a
25	P01116_2XR	2XR	n/a	152961	n/a	2-chloro-1-(1H-indol-3-yl)ethanone	n/a
26	P01116_5UT	5UT	n/a	86279165	CHEMBL4476113	1-[3-[4-[2-[[4-chloranyl-5-(1-methylcyclopropyl)-2-oxidanyl-phenyl]amino]ethanoyl]piperazin-1-yl]azetidin-1-yl]prop-2-en-1-one	n/a
27	P01116_6IC	6IC	n/a	162369732	CHEMBL5081048	4-(4-[(1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl]-8-fluoro-2-{[(2R,4R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}pyrido[4,3-d]pyrimidin-7-yl)-5-ethynyl-6-fluoronaphthalen-2-ol	n/a
28	P01116_6ZD	6ZD	n/a	134156761;137316471;	CHEMBL3982443	5'-O-[(R)-[({2-[(chloroacetyl)amino]ethyl}sulfamoyl)methyl](hydroxy)phosphoryl]guanosine	n/a
29	P01116_7IZ	7IZ	n/a	155233433	CHEMBL5084171	7-(8-chloronaphthalen-1-yl)-8-fluoro-2-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}-4-(piperazin-1-yl)pyrido[4,3-d]pyrimidine	n/a
30	P01116_7L8	7L8	n/a	156117314	CHEMBL5080840	4-(4-[(1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl]-8-fluoro-2-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}pyrido[4,3-d]pyrimidin-7-yl)naphthalen-2-ol	n/a
31	P01116_7NL	7NL	n/a	n/a	CHEMBL5089133	4-(4-[(1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl]-8-fluoro-2-{[(2R,4R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}pyrido[4,3-d]pyrimidin-7-yl)naphthalen-2-ol	n/a
32	P01116_7NZ	7NZ	n/a	162369734	CHEMBL5093274	4-(4-[(1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl]-8-fluoro-2-{[(2S,4S,7aR)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}pyrido[4,3-d]pyrimidin-7-yl)naphthalen-2-ol	n/a
33	P01116_7OE	7OE	n/a	162369735	CHEMBL5087229	4-[(1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl]-7-(8-ethynyl-7-fluoronaphthalen-1-yl)-8-fluoro-2-{[(4s,7as)-tetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}pyrido[4,3-d]pyrimidine	n/a
34	P01116_7Q9	7Q9	n/a	156600309	n/a	[(2~{R})-3-[oxidanyl-[2-(trimethyl-$l^{4}-azanyl)ethoxy]phosphoryl]oxy-2-propanoyloxy-propyl] (~{Z})-octadec-9-enoate	n/a
35	P01116_8YA	8YA	n/a	137348769	n/a	3-amino-1-{4-[6-chloro-8-fluoro-7-(5-methyl-1H-indazol-4-yl)quinazolin-4-yl]piperazin-1-yl}propan-1-one	n/a
36	P01116_8YD	8YD	n/a	130377679	n/a	1-{4-[6-chloro-8-fluoro-7-(5-methyl-1H-indazol-4-yl)quinazolin-4-yl]piperazin-1-yl}propan-1-one	n/a
37	P01116_8ZG	8ZG	n/a	137348773	n/a	1-{4-[6-chloro-7-(2-fluorophenyl)quinazolin-4-yl]piperazin-1-yl}propan-1-one	n/a
38	P01116_91D	91D	n/a	137348777	n/a	N~3~-[6-chloro-7-(2-fluorophenyl)-4-(4-propanoylpiperazin-1-yl)quinazolin-2-yl]-N,N-dimethyl-beta-alaninamide	n/a
39	P01116_91G	91G	n/a	137348778	n/a	N~3~-[6-chloro-7-(3-hydroxynaphthalen-1-yl)-4-(4-propanoylpiperazin-1-yl)quinazolin-2-yl]-N,N-dimethyl-beta-alaninamide	n/a
40	P01116_91S	91S	n/a	137181409	n/a	(S)-1-{4-[6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl] piperazin-1-yl}propan-1-one	n/a
41	P01116_92V	92V	n/a	131704455	n/a	1-(4-methoxyphenyl)-N-(3-sulfanylpropyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide	n/a
42	P01116_94C	94C	n/a	137348785	n/a	1-[4-[6-chloranyl-8-fluoranyl-7-(2-fluorophenyl)quinazolin-4-yl]piperazin-1-yl]propan-1-one	n/a
43	P01116_94F	94F	n/a	137348786	n/a	1-[4-[6-chloranyl-8-fluoranyl-7-[2-(trifluoromethyl)phenyl]quinazolin-4-yl]piperazin-1-yl]propan-1-one	n/a
44	P01116_9GM	9GM	n/a	92471058;135567335;	n/a	2-amino-9-{5-O-[(S)-hydroxy{[(R)-hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]-alpha-L-xylofuranosyl}-1,9-dihydro-6H-purin-6-one	n/a
45	P01116_9LI	9LI	n/a	1381961	CHEMBL2396992	2-(4,6-dichloro-2-methyl-1H-indol-3-yl)ethanamine	n/a
46	P01116_9R5	9R5	n/a	73424803	n/a	[(2~{R})-6-chloranyl-2,3-dihydro-1,4-benzodioxin-2-yl]methanamine	n/a
47	P01116_9RK	9RK	n/a	694893	n/a	~{N}-[[(3~{R})-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]furan-2-carboxamide	n/a
48	P01116_ACE	ACE	n/a	177	CHEMBL170365	ACETYL GROUP	n/a
49	P01116_ACT	ACT	DB14511	175	n/a	ACETATE ION	n/a
50	P01116_BEN	BEN	n/a	2332	CHEMBL20936	BENZAMIDINE	n/a
51	P01116_BQD	BQD	n/a	137349018	n/a	(3R)-N-(6-bromonaphthalen-2-yl)-3-hydroxy-1-propanoyl-L-prolinamide	n/a
52	P01116_BZI	BZI	DB02962	5798	CHEMBL306226	BENZIMIDAZOLE	n/a
53	P01116_C8G	C8G	n/a	137349063	n/a	1-[3-(4-{[(4,5-dichloro-2-hydroxyphenyl)amino]acetyl}piperazin-1-yl)azetidin-1-yl]propan-1-one	n/a
54	P01116_CA	CA	n/a	271	n/a	CALCIUM ION	n/a
55	P01116_CD	CD	n/a	31193	n/a	CADMIUM ION	n/a
56	P01116_CIT	CIT	DB04272	311;19782904;88113319;	CHEMBL1261	CITRIC ACID	n/a
57	P01116_CL	CL	n/a	312	n/a	CHLORIDE ION	n/a
58	P01116_CO	CO	n/a	104729	n/a	COBALT (II) ION	n/a
59	P01116_CVK	CVK	n/a	134693857	n/a	4-(2,3-dihydro-1,4-benzodioxin-5-yl)-~{N}-[3-[(dimethylamino)methyl]phenyl]-2-methoxy-aniline	n/a
60	P01116_D1W	D1W	n/a	134812710	CHEMBL4456044	6-(2,3-dihydro-1,4-benzodioxin-5-yl)-~{N}-[4-[(dimethylamino)methyl]phenyl]-2-methoxy-pyridin-3-amine	n/a
61	P01116_D1Z	D1Z	n/a	134812709	n/a	~{N}-[[(3~{R})-5-[5-[[3-[(dimethylamino)methyl]phenyl]amino]-6-methoxy-pyridin-2-yl]-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]oxane-4-carboxamide	n/a
62	P01116_D2W	D2W	n/a	134812708	n/a	4-[2-(dimethylamino)ethoxy]-~{N}-[[(3~{R})-5-(6-methoxypyridin-2-yl)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]benzamide	n/a
63	P01116_D2Z	D2Z	n/a	137349149	n/a	2-[4-[[(3~{R})-2,3-dihydro-1,4-benzodioxin-3-yl]methylcarbamoyl]phenoxy]ethyl-dimethyl-azanium	n/a
64	P01116_DMS	DMS	DB01093	679	CHEMBL504	DIMETHYL SULFOXIDE	n/a
65	P01116_EDO	EDO	n/a	174	CHEMBL457299	1,2-ETHANEDIOL	n/a
66	P01116_EWS	EWS	n/a	134812652	n/a	(2R,4S)-4-[(5-bromo-1H-indole-3-carbonyl)amino]-2-[(4-chlorophenyl)methyl]piperidin-1-ium	n/a
67	P01116_EZZ	EZZ	n/a	138756244	CHEMBL4796065	(3~{S})-3-[2-[(dimethylamino)methyl]-1~{H}-indol-3-yl]-5-oxidanyl-2,3-dihydroisoindol-1-one	n/a
68	P01116_F0B	F0B	n/a	138756245	CHEMBL4788500	(3~{S})-5-oxidanyl-3-[2-[[[1-(phenylmethyl)indol-6-yl]methylamino]methyl]-1~{H}-indol-3-yl]-2,3-dihydroisoindol-1-one	n/a
69	P01116_F0K	F0K	n/a	138756246	CHEMBL4750445	(3~{S})-3-[2-[[[1-[(1-methylimidazol-4-yl)methyl]indol-6-yl]methylamino]methyl]-1~{H}-indol-3-yl]-5-oxidanyl-2,3-dihydroisoindol-1-one	n/a
70	P01116_F0N	F0N	n/a	138756243	n/a	(3~{S})-3-[2-[(2~{R})-pyrrolidin-2-yl]-1~{H}-indol-3-yl]-2,3-dihydroisoindol-1-one	n/a
71	P01116_F6E	F6E	n/a	129568534	n/a	(6~{S})-1-(1~{H}-imidazol-4-ylcarbonyl)-6-[(4-phenylphenyl)methyl]-4-propyl-1,4-diazepan-5-one	n/a
72	P01116_F8K	F8K	n/a	137349328	n/a	[4-[[2-methoxy-4-(3-methoxyphenyl)phenyl]amino]phenyl]methyl-dimethyl-azanium	n/a
73	P01116_F8N	F8N	n/a	129453898	n/a	~{N}-(3-imidazol-1-ylpropyl)-4-[[3-(3-methoxyphenyl)phenyl]methyl]oxane-4-carboxamide	n/a
74	P01116_F8Q	F8Q	n/a	137349329	n/a	[4-[[3-fluoranyl-2-methoxy-4-(3-methoxyphenyl)phenyl]amino]phenyl]methyl-dimethyl-azanium	n/a
75	P01116_F8T	F8T	n/a	137349330	n/a	[4-[[4-(3-methoxyphenyl)phenyl]amino]phenyl]methyl-dimethyl-azanium	n/a
76	P01116_FAR	FAR	n/a	444108	n/a	FARNESYL	n/a
77	P01116_FMT	FMT	DB01942	284;18971002;	CHEMBL116736	FORMIC ACID	n/a
78	P01116_GCP	GCP	DB03725	93082;5280942;135398731;	n/a	PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER	n/a
79	P01116_GDP	GDP	DB04315	8977;5280316;135398619;	CHEMBL384759	GUANOSINE-5'-DIPHOSPHATE	n/a
80	P01116_GLC	GLC	n/a	79025	CHEMBL423707	alpha-D-glucopyranose	n/a
81	P01116_GLY	GLY	DB00145	750;5257127;	CHEMBL773	GLYCINE	n/a
82	P01116_GNP	GNP	DB02082	36735;5288455;135403657;	CHEMBL1233085	PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	n/a
83	P01116_GOL	GOL	DB09462	753	CHEMBL692	GLYCEROL	n/a
84	P01116_GSP	GSP	DB01864	37792;444121;5280465;135398675;135450576;	CHEMBL1204628	5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE	n/a
85	P01116_GTP	GTP	DB04137	6830;5280317;135398633;	CHEMBL1233147	GUANOSINE-5'-TRIPHOSPHATE	n/a
86	P01116_H0O	H0O	n/a	163321791	n/a	~{N}-[4-[3,5-dimethyl-4-(5-methyl-2~{H}-indazol-4-yl)pyrazol-1-yl]phenyl]propanamide	n/a
87	P01116_H2T	H2T	n/a	163321792	n/a	1-[6-[4-(5-chloranyl-6-methyl-1~{H}-indazol-4-yl)-5-methyl-3-(1-methylindazol-5-yl)pyrazol-1-yl]-2-azaspiro[3.3]heptan-2-yl]propan-1-one	n/a
88	P01116_H40	H40	n/a	163321793	n/a	~{N}-[4-[2-bromanyl-6-(2-hydroxyethylamino)pyridin-4-yl]sulfanylphenyl]propanamide	n/a
89	P01116_I6T	I6T	n/a	164607210	n/a	(3R,4R)-1-[7-(8-chloronaphthalen-1-yl)-2-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl]-3-hydroxypiperidine-4-carbaldehyde	n/a
90	P01116_I7H	I7H	n/a	164607211	n/a	(3R,4R)-1-[7-(8-chloronaphthalen-1-yl)-8-fluoro-2-{[(4S,7as)-tetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}pyrido[4,3-d]pyrimidin-4-yl]-3-hydroxypiperidine-4-carbaldehyde	n/a
91	P01116_IOD	IOD	n/a	30165	n/a	IODIDE ION	n/a
92	P01116_IQC	IQC	n/a	164607212	n/a	1-[7-[6-chloranyl-8-fluoranyl-7-(5-methyl-1~{H}-indazol-4-yl)-2-[(1-methylpiperidin-4-yl)amino]quinazolin-4-yl]-2,7-diazaspiro[3.5]nonan-2-yl]propan-1-one	n/a
93	P01116_IQN	IQN	n/a	164607213	n/a	1-[7-[6-chloranyl-2-(1-ethylpiperidin-4-yl)oxy-8-fluoranyl-7-(5-methyl-1~{H}-indazol-4-yl)quinazolin-4-yl]-2,7-diazaspiro[3.5]nonan-2-yl]propan-1-one	n/a
94	P01116_JJN	JJN	n/a	138756271	n/a	(6~{a}~{R},11~{b}~{S})-6~{a}-(1,4-dimethylpiperidin-4-yl)-7,11~{b}-dihydro-6~{H}-indolo[2,3-c]isoquinolin-5-one	n/a
95	P01116_JJQ	JJQ	n/a	138756272	n/a	(3~{a}~{R},8~{b}~{S})-2,2,3~{a},8~{b}-tetramethyl-3,4-dihydro-1~{H}-pyrrolo[2,3-b]indole	n/a
96	P01116_K9J	K9J	n/a	137349634	n/a	1-{4-[2-{[(2R)-1-(dimethylamino)propan-2-yl]oxy}-7-(3-hydroxynaphthalen-1-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl]piperazin-1-yl}propan-1-one	n/a
97	P01116_K9M	K9M	n/a	137349635	n/a	1-{4-[7-(naphthalen-1-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl]piperazin-1-yl}propan-1-one	n/a
98	P01116_LR4	LR4	n/a	168268164	n/a	(4~{S})-2-azanyl-4-[3-[6-[(2~{S})-2,4-dimethylpiperazin-1-yl]pyridin-2-yl]-1,2,4-oxadiazol-5-yl]-4-methyl-6,7-dihydro-5~{H}-1-benzothiophene-3-carbonitrile	n/a
99	P01116_LX6	LX6	n/a	78382	CHEMBL1632047	2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carbonitrile	n/a
100	P01116_LXD	LXD	n/a	165416585	CHEMBL5218642	(4~{S})-2-azanyl-4-[3-[6-[(2~{S})-2,4-dimethylpiperazin-1-yl]-4-(4-prop-2-enoylpiperazin-1-yl)pyridin-2-yl]-1,2,4-oxadiazol-5-yl]-4-methyl-6,7-dihydro-5~{H}-1-benzothiophene-3-carbonitrile	n/a
101	P01116_LXK	LXK	n/a	79841256	CHEMBL5219175	2-azanyl-4,4-dimethyl-6,7-dihydro-5~{H}-1-benzothiophene-3-carbonitrile	n/a
102	P01116_LXU	LXU	n/a	165416411	CHEMBL5219570	(4~{S})-4-[3-(4-aminophenyl)-1,2,4-oxadiazol-5-yl]-2-azanyl-4-methyl-6,7-dihydro-5~{H}-1-benzothiophene-3-carbonitrile	n/a
103	P01116_M1R	M1R	n/a	146020601	n/a	1-{4-[2-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}-7-(naphthalen-1-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl]piperazin-1-yl}propan-1-one	n/a
104	P01116_M1X	M1X	n/a	146020603	n/a	{(2S)-4-[7-(8-chloronaphthalen-1-yl)-2-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl]-1-[(2S)-2-fluoropropanoyl]piperazin-2-yl}acetonitrile	n/a
105	P01116_MG	MG	n/a	888	n/a	MAGNESIUM ION	n/a
106	P01116_MKZ	MKZ	n/a	145946084	n/a	1-[4-[6-chloranyl-7-(5-methyl-1~{H}-indazol-4-yl)quinazolin-4-yl]piperazin-1-yl]propan-1-one	n/a
107	P01116_MOV	MOV	n/a	145946085	n/a	AMG 510 (bound form)	n/a
108	P01116_MPD	MPD	DB03564	5288834	n/a	(4S)-2-METHYL-2,4-PENTANEDIOL	n/a
109	P01116_MZN	MZN	n/a	146018703	n/a	7-(2-fluoranyl-6-oxidanyl-phenyl)-3-[(3~{R})-1-propanoylpyrrolidin-3-yl]-4~{H}-2,6-naphthyridin-1-one	n/a
110	P01116_MZQ	MZQ	n/a	146018704	n/a	7-[2,4-bis(fluoranyl)phenyl]-3-[(3~{R})-1-propanoylpyrrolidin-3-yl]-4~{H}-isoquinolin-1-one	n/a
111	P01116_NA	NA	n/a	923	n/a	SODIUM ION	n/a
112	P01116_NO3	NO3	DB14049	943	CHEMBL186200	NITRATE ION	n/a
113	P01116_NZ6	NZ6	n/a	166001311	n/a	1-[6-[4-(5-chloranyl-6-methyl-1~{H}-indazol-4-yl)-5-methyl-3-phenyl-pyrazol-1-yl]-2-azaspiro[3.3]heptan-2-yl]propan-1-one	n/a
114	P01116_NZX	NZX	n/a	166001312	n/a	1-[6-[3-cyclohexyl-5-methyl-4-(5-methyl-1~{H}-indazol-4-yl)pyrazol-1-yl]-2-azaspiro[3.3]heptan-2-yl]propan-1-one	n/a
115	P01116_O5S	O5S	n/a	145946102	n/a	2-[5-chloro-2-cyclopropyl-3-(5-methoxy-3,4-dihydroisoquinoline-2(1H)-carbonyl)-7-methyl-1H-indol-1-yl]-N-(1-propanoylazetidin-3-yl)acetamide	n/a
116	P01116_O5V	O5V	n/a	145946103	n/a	2-[4-bromo-2-(3-phenyl-2,5-dihydro-1H-pyrrole-1-carbonyl)phenoxy]-N-(1-propanoylazetidin-3-yl)acetamide	n/a
117	P01116_O5Y	O5Y	n/a	145946104	n/a	2-[5-bromo-3-(5-methoxy-3,4-dihydroisoquinoline-2(1H)-carbonyl)-1H-indol-1-yl]-N-(1-propanoylazetidin-3-yl)acetamide	n/a
118	P01116_O67	O67	n/a	145946105	n/a	N-(5-bromo-2-{2-oxo-2-[(1-propanoylazetidin-3-yl)amino]ethoxy}phenyl)-3-methyl-1,2-oxazole-5-carboxamide	n/a
119	P01116_O7K	O7K	n/a	145946106	n/a	pyrazinoquinolinone	n/a
120	P01116_OFU	OFU	n/a	168268165	n/a	(4S)-2-azanyl-4-methyl-4-[3-[4-[(1S)-1-[(2S)-1-methylpyrrolidin-1-ium-2-yl]ethoxy]pyrimidin-2-yl]-1,2,4-oxadiazol-5-yl]-6,7-dihydro-5H-1-benzothiophene-3-carbonitrile	n/a
121	P01116_OHY	OHY	n/a	145946107	n/a	6-chloro-7-(2-fluoro-6-hydroxyphenyl)-4-(4-propanoylpiperazin-1-yl)-1-[2-(propan-2-yl)phenyl]quinazolin-2(1H)-one	n/a
122	P01116_OJ1	OJ1	n/a	145946108	n/a	1-{4-[7-chloro-6-(2-fluoro-6-hydroxyphenyl)-4-phenylphthalazin-1-yl]piperazin-1-yl}propan-1-one	n/a
123	P01116_P2Z	P2Z	DB00420	4926	CHEMBL564	Promazine	n/a
124	P01116_P7U	P7U	n/a	164885974	n/a	{(2S)-4-[(7P)-7-(8-chloronaphthalen-1-yl)-8-fluoro-2-{[(4R,7as)-tetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}pyrido[4,3-d]pyrimidin-4-yl]-1-[(3S)-2,2,3-trihydroxybutanoyl]piperazin-2-yl}acetonitrile	n/a
125	P01116_PCW	PCW	DB03690	448653	n/a	1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE	n/a
126	P01116_PEG	PEG	n/a	8117	CHEMBL1235226	DI(HYDROXYETHYL)ETHER	n/a
127	P01116_PG4	PG4	n/a	8200	CHEMBL1235254	TETRAETHYLENE GLYCOL	n/a
128	P01116_PGE	PGE	DB02327	8172	CHEMBL1235259	TRIETHYLENE GLYCOL	n/a
129	P01116_PO4	PO4	DB14523	1061	n/a	PHOSPHATE ION	n/a
130	P01116_PQI	PQI	n/a	168451675	n/a	1-[(4~{a}~{S})-7-chloranyl-8-(5-methyl-2~{H}-indazol-4-yl)-1,2,4,4~{a},5,11-hexahydropyrazino[2,1-c][1,4]benzoxazepin-3-yl]propan-1-one	n/a
131	P01116_PUO	PUO	n/a	168451676	n/a	1-[(4~{a}~{R})-8-(2-chloranyl-6-oxidanyl-phenyl)-7-fluoranyl-9-prop-1-ynyl-1,2,4,4~{a},5,11-hexahydropyrazino[2,1-c][1,4]benzoxazepin-3-yl]propan-1-one	n/a
132	P01116_QH4	QH4	n/a	146035923	n/a	{(2S)-4-[2-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}-7-(naphthalen-1-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl]-1-propanoylpiperazin-2-yl}acetonitrile	n/a
133	P01116_QME	QME	n/a	36690643	n/a	2-[(2~{R})-piperidin-2-yl]-1~{H}-indole	n/a
134	P01116_QPD	QPD	n/a	33478959	n/a	(2R)-2-[2-(1H-indole-3-carbonyl)hydrazinyl]-2-phenylacetamide	n/a
135	P01116_QWB	QWB	n/a	792486	CHEMBL116794	3-(imidazol-1-ylmethyl)-1~{H}-indole	n/a
136	P01116_QWH	QWH	n/a	156613442	n/a	~{N}-(3-bromanyl-2,6-dimethyl-pyridin-4-yl)propanamide	n/a
137	P01116_QWK	QWK	n/a	156613443	n/a	~{N}-[6-(phenylmethyl)-7,8-dihydro-5~{H}-pyrido[4,3-d]pyrimidin-2-yl]propanamide	n/a
138	P01116_QY5	QY5	n/a	156613444	n/a	~{N}-[3-bromanyl-2-(2-methylimidazol-1-yl)pyridin-4-yl]-3-[[3-bromanyl-2-(2-methylimidazol-1-yl)pyridin-4-yl]-propanoyl-amino]propanamide	n/a
139	P01116_R6W	R6W	n/a	154815691	n/a	(3~{S})-5-oxidanyl-3-[2-[[6-[[3-[(1~{S})-6-oxidanyl-3-oxidanylidene-1,2-dihydroisoindol-1-yl]-1~{H}-indol-2-yl]methylamino]hexylamino]methyl]-1~{H}-indol-3-yl]-2,3-dihydroisoindol-1-one	n/a
140	P01116_SO4	SO4	DB14546	1117	n/a	SULFATE ION	n/a
141	P01116_TCE	TCE	n/a	119411	CHEMBL171512	3,3',3''-phosphanetriyltripropanoic acid	n/a
142	P01116_TRS	TRS	DB03754	3777159;88088752;152743085;	n/a	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	n/a
143	P01116_U4L	U4L	n/a	164885979	n/a	(4P)-4-(5-methyl-1H-indazol-4-yl)-6-(2-propanoyl-2,6-diazaspiro[3.4]octan-6-yl)-2-(pyrrolidin-1-yl)pyrimidine-5-carbonitrile	n/a
144	P01116_U4U	U4U	n/a	164885980	n/a	1-[(5S,9P,12aR)-9-(2-chloro-6-hydroxyphenyl)-8-ethynyl-10-fluoro-3,4,12,12a-tetrahydro-6H-pyrazino[2,1-c][1,4]benzoxazepin-2(1H)-yl]propan-1-one	n/a
145	P01116_U50	U50	n/a	164885981	n/a	2-{[(5-tert-butyl-6-chloro-1H-indazol-3-yl)amino]methyl}-4-chloro-1-methyl-N-(1-propanoylazetidin-3-yl)-1H-imidazole-5-carboxamide	n/a
146	P01116_UNX	UNX					n/a
147	P01116_V4T	V4T	n/a	146250992	CHEMBL5183988	1-[(4R,7S)-12-chloro-14-fluoro-13-(2-fluoro-6-hydroxyphenyl)-4-methyl-10-oxa-2,5,16,18-tetrazatetracyclo[9.7.1.0^(2,7).0^(15,19)]nonadeca-1(18),11,13,15(19),16-pentaen-5-en-1-one-yl]prop-2	n/a
148	P01116_VJ8	VJ8	n/a	164607235	n/a	edaGDP	n/a
149	P01116_VJB	VJB	n/a	164607236	n/a	bdaGDP	n/a
150	P01116_VLE	VLE	n/a	163321841	n/a	1-[(6aS)-3-chloro-2-(5-methyl-1H-indazol-4-yl)-5,6,6a,7,9,10-hexahydro-8H-pyrazino[1',2':5,6][1,5]oxazocino[4,3,2-de]quinazolin-8-yl]-2-propen-1-one	n/a
151	P01116_VM9	VM9	n/a	169408441	n/a	(6M)-6-(6-chloro-4-[(1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl]-8-fluoro-2-{[(2R,4R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}quinazolin-7-yl)-4-methyl-5-(trifluoromethyl)pyridin-2-amine	n/a
152	P01116_VQT	VQT	n/a	169408442	n/a	(4M)-4-(6-chloro-4-[(1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl]-8-fluoro-2-{[(2R,4R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}quinazolin-7-yl)-7-fluoro-1,3-benzothiazol-2-amine	n/a
153	P01116_VR5	VR5	n/a	164904636	n/a	(4P)-2-amino-4-{4-[(1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl]-8-fluoro-2-{[(2R,4R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}-6-(trifluoromethyl)quinazolin-7-yl}-7-fluoro-1-benzothiophene-3-carbonitrile	n/a
154	P01116_VU6	VU6	n/a	168268198	n/a	(7~{S})-2'-azanyl-3-[2-[(2~{S})-2-methylpiperazin-1-yl]pyrimidin-4-yl]spiro[5,6-dihydro-4~{H}-1,2-benzoxazole-7,4'-6,7-dihydro-5~{H}-1-benzothiophene]-3'-carbonitrile	n/a
155	P01116_Y9Z	Y9Z	n/a	74049863;135566893;	n/a	5'-O-[(S)-{[(S)-[2-(acetylamino)ethoxy](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]guanosine	n/a
156	P01116_YV2	YV2	n/a	168451755	n/a	(2S)-2-{(5S)-7-[(2E)-4-(dimethylamino)-4-methylpent-2-enoyl]-1-oxo-2,7-diazaspiro[4.4]nonan-2-yl}-N-[(1P,8S,10R,14S,21M)-22-ethyl-21-{2-[(1S)-1-methoxyethyl]pyridin-3-yl}-18,18-dimethyl-9,15-dioxo-16-oxa-10,22,28-triazapentacyclo[18.5.2.1~2,6~.1~10,14~.0~23,27~]nonacosa-1(25),2(29),3,5,20,23,26-heptaen-8-yl]-3-methylbutanamide (non-preferred name)	n/a
157	P01116_YV6	YV6	n/a	168458713	n/a	methyl (3S)-1-[N-(4-sulfanylbutanoyl)-L-valyl-3-hydroxy-L-phenylalanyl]-1,2-diazinane-3-carboxylate	n/a
158	P01116_Z07	Z07	n/a	108937	CHEMBL5220787	4-(trifluoromethyl)-1,3-benzothiazol-2-amine	n/a
159	P01116_ZM7	ZM7	n/a	688096	CHEMBL1788267	(2R)-N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine	n/a
160	P01116_ZN	ZN	n/a	32051	CHEMBL1236970	ZINC ION	n/a
161	P01116_FII	FII	DB07771	445015	n/a	[(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID	n/a
162	P01116_FPP	FPP	DB07780	445713	CHEMBL69330	Farnesyl diphosphate	n/a
163	P01116_DB15568	n/a	DB15568	n/a	n/a	Adagrasib	inhibitor
164	P01116_DB15569	n/a	DB15569	n/a	n/a	Sotorasib	inhibitor