Gene name: RAF1
Protein name: RAF proto-oncogene serine/threonine-protein
List of molecules and drugs that interact with protein P04049
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P04049_17F | 17F | DB18573 | 6438639;44825325; | CHEMBL4165044 | O-[(S)-({(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl}oxy)(hydroxy)phosphoryl]-L-serine | n/a | |
| 2 | P04049_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 3 | P04049_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 4 | P04049_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 5 | P04049_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 6 | P04049_IPA | IPA | DB02325 | 3776 | CHEMBL582 | ISOPROPYL ALCOHOL | n/a | |
| 7 | P04049_PCW | PCW | DB03690 | 448653 | n/a | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | n/a | |
| 8 | P04049_SM5 | SM5 | DB08553 | 11653652 | CHEMBL526479 | (1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime | n/a | |
| 9 | P04049_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 10 | P04049_BAX | BAX | DB00398 | 216239 | CHEMBL1336 | Sorafenib | inhibitor | IC50(nM) = 1.0 Kd(nM) = 230.0 |
| 11 | P04049_DB08896 | n/a | DB08896 | n/a | n/a | Regorafenib | inhibitor | IC50(nM) = 1.5 |
| 12 | P04049_P06 | P06 | DB08912 | 44462760 | CHEMBL2028663 | Dabrafenib | inhibitor | IC50(nM) = 5.0 |
| 13 | P04049_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor |