Gene name: ache
Protein name: Acetylcholinesterase (AChE) (EC
List of molecules and drugs that interact with protein P04058
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P04058_03S | 03S | n/a | 6395;20271438; | CHEMBL3039600 | methanesulfonic acid | n/a | |
| 2 | P04058_1PE | 1PE | n/a | 62551 | CHEMBL1229766 | PENTAETHYLENE GLYCOL | n/a | |
| 3 | P04058_1PG | 1PG | DB02042 | 90255 | CHEMBL1229767 | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL | n/a | |
| 4 | P04058_4VV | 4VV | n/a | 137348292 | n/a | (Z,Z)-[heptane-1,7-diylbis(1H-imidazol-1-yl-2-ylidene)]bis(N-hydroxymethanamine) | n/a | |
| 5 | P04058_8U2 | 8U2 | n/a | n/a | n/a | 2-{1-[4-(12-Amino-3-chloro-6,7,10,11-tetrahydro-7,11-methanocycloocta[b]quinolin-9-yl)butyl]-1H-1,2,3-triazol-4-yl}-N-[4-hydroxy-3-methoxybenzyl]acetamide | n/a | |
| 6 | P04058_8U5 | 8U5 | n/a | n/a | n/a | E)-10-[(3-Chloro-6,7,10,11-tetrahydro-9-methyl-7,11-methanocycloocta[b]quinolin-12-yl)amino]-N-(4-hydroxy-3-methoxybenzyl)-6-decenamide | n/a | |
| 7 | P04058_8UE | 8UE | n/a | 156612852 | n/a | 4-{[(3-Chloro-6,7,10,11-tetrahydro-9-methyl-7,11-methanocycloocta[b]quinolin-12-yl)amino]methyl}-N-(4-hydroxy-3-methoxybenzyl)benzamide | n/a | |
| 8 | P04058_8UH | 8UH | n/a | 156613440 | n/a | 6-[(3-Chloro-6,7,10,11-tetrahydro-9-methyl-7,11-methanocycloocta[b]quinolin-12-yl)amino]-N-(4-hydroxy-3-methoxybenzyl)hexanamide | n/a | |
| 9 | P04058_8UK | 8UK | n/a | 156612850 | n/a | 7-[(3-Chloro-6,7,10,11-tetrahydro-9-methyl-7,11-methanocycloocta[b]quinolin-12-yl)amino]-N-(4-hydroxy-3-methoxybenzyl)heptanamide | n/a | |
| 10 | P04058_8UQ | 8UQ | n/a | n/a | n/a | 8-[(3-Chloro-6,7,10,11-tetrahydro-9-methyl-7,11-methanocycloocta[b]quinolin-12-yl)amino]-N-(4-hydroxy-3-methoxybenzyl)octanamide | n/a | |
| 11 | P04058_9A5 | 9A5 | n/a | 134129088 | CHEMBL4596071 | (2~{S})-2-azanyl-~{N}-[6-[(6-chloranyl-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl]-3-(1~{H}-indol-3-yl)propanamide | n/a | |
| 12 | P04058_A1E | A1E | DB04614 | 5287575;5326966; | n/a | (5R)-5-{[10-(1,2,3,4-TETRAHYDROACRIDIN-9-YLAMINO)DECYL]AMINO}-5,6,7,8-TETRAHYDROQUINOLIN-2(1H)-ONE | n/a | |
| 13 | P04058_A2E | A2E | DB04615 | 5287576;5326967; | n/a | (5S)-5-{[10-(1,2,3,4-TETRAHYDROACRIDIN-9-YLAMINO)DECYL]AMINO}-5,6,7,8-TETRAHYDROQUINOLIN-2(1H)-ONE | n/a | |
| 14 | P04058_A8B | A8B | DB04616 | 656986 | CHEMBL1082738 | N-QUINOLIN-4-YL-N'-(1,2,3,4-TETRAHYDROACRIDIN-9-YL)OCTANE-1,8-DIAMINE | n/a | |
| 15 | P04058_A8N | A8N | DB04617 | 5287586 | n/a | N-9-(1',2',3',4'-TETRAHYDROACRIDINYL)-1,8-DIAMINOOCTANE | n/a | |
| 16 | P04058_AA7 | AA7 | n/a | 9549196 | CHEMBL32823 | N,N'-DI-1,2,3,4-TETRAHYDROACRIDIN-9-YLHEPTANE-1,7-DIAMINE | n/a | |
| 17 | P04058_ACE | ACE | n/a | 177 | CHEMBL170365 | ACETYL GROUP | n/a | |
| 18 | P04058_ACH | ACH | DB03128 | 187 | CHEMBL667 | ACETYLCHOLINE | n/a | |
| 19 | P04058_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 20 | P04058_AE4 | AE4 | DB07344 | 78058 | n/a | 3,6,9,12,15-PENTAOXAHEPTADECAN-1-OL | n/a | |
| 21 | P04058_AFT | AFT | n/a | 186907 | CHEMBL1697694 | AFLATOXIN B1 | n/a | |
| 22 | P04058_AT3 | AT3 | n/a | 20544 | CHEMBL1231076 | ACETYLTHIOCHOLINE | n/a | |
| 23 | P04058_BM4 | BM4 | n/a | 49866713 | n/a | 3-[(3R)-3-ethyl-1-{9-[(3S)-3-ethyl-3-(3-hydroxyphenyl)azepan-1-yl]nonyl}azepan-3-yl]phenol | n/a | |
| 24 | P04058_C6H | C6H | n/a | 134828071 | CHEMBL4537101 | 1-(7-chloranyl-4-methoxy-1~{H}-indol-5-yl)-3-[1-(cyclohexylmethyl)piperidin-4-yl]propan-1-one | n/a | |
| 25 | P04058_C6K | C6K | n/a | 134828069 | CHEMBL4526050 | 1-(7-chloranyl-4-methoxy-1~{H}-indol-5-yl)-3-[1-(phenylmethyl)piperidin-4-yl]propan-1-one | n/a | |
| 26 | P04058_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 27 | P04058_CCD | CCD | n/a | 24916842 | n/a | (4R)-4-HYDROXY-N,N,N-TRIMETHYLPENTAN-1-AMINIUM | n/a | |
| 28 | P04058_CFQ | CFQ | DB07555 | n/a | n/a | 1-(2-nitrophenyl)-2,2,2-trifluoroethyl]-arsenocholine | n/a | |
| 29 | P04058_CHH | CHH | n/a | 91420 | CHEMBL136916 | N,N,N-TRIMETHYL-4-OXOPENTAN-1-AMINIUM | n/a | |
| 30 | P04058_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 31 | P04058_CP0 | CP0 | DB00762 | 60838 | CHEMBL481 | (4S)-4,11-DIETHYL-4-HYDROXY-3,14-DIOXO-3,4,12,14-TETRAHYDRO-1H-PYRANO[3',4':6,7]INDOLIZINO[1,2-B]QUINOLIN-9-YL 1,4'-BIPIPERIDINE-1'-CARBOXYLATE | n/a | Ki(nM) = 26.0 |
| 32 | P04058_DME | DME | DB01245 | 2968 | CHEMBL1190 | DECAMETHONIUM ION | n/a | |
| 33 | P04058_DQ5 | DQ5 | n/a | 135567438 | CHEMBL3234588 | 2-[(~{E})-hydroxyiminomethyl]-6-[4-(1,2,3,4-tetrahydroacridin-9-ylamino)butyl]pyridin-3-ol | n/a | |
| 34 | P04058_DZ0 | DZ0 | n/a | 10521609 | CHEMBL3818084 | (2~{E})-5-methoxy-2-[[1-(phenylmethyl)piperidin-4-yl]methylidene]-3~{H}-inden-1-one | n/a | |
| 35 | P04058_DZ7 | DZ7 | n/a | 10762160 | CHEMBL168938 | (2~{E})-5,6-dimethoxy-2-[[1-(phenylmethyl)piperidin-4-yl]methylidene]-3~{H}-inden-1-one | n/a | |
| 36 | P04058_E0Z | E0Z | n/a | 132472272 | n/a | 2-[1-[2-[(3-chloranylacridin-9-yl)amino]ethyl]-1,2,3-triazol-4-yl]-~{N}-[(3-methoxy-4-oxidanyl-phenyl)methyl]ethanamide | n/a | |
| 37 | P04058_E10 | E10 | n/a | 445974;5288142; | CHEMBL483090 | (S,S)-(-)-N,N'-DI-5'-[5',6',7',8'-TETRAHYDRO- 2'(1'H)-QUINOLYNYL]-1,10-DIAMINODECANE DIHYDROCHLORIDE | n/a | |
| 38 | P04058_E12 | E12 | n/a | 445975;5288143; | CHEMBL519154 | (S,S)-(-)-N,N'-DI-5'-[5',6',7',8'-TETRAHYDRO- 2'(1'H)-QUINOLYNYL]-1,12-DIAMINODODECANE DIHYDROCHLORIDE | n/a | |
| 39 | P04058_E1K | E1K | n/a | 132472270 | n/a | 6-chloranyl-10-methyl-1,2,3,4-tetrahydroacridin-10-ium-9-amine | n/a | |
| 40 | P04058_E1N | E1N | n/a | 132472271 | n/a | 12-Amino-3-chloro-6,7,10,11-tetrahydro-5,9-dimethyl-7,11-methanocycloocta[b]quinolin-5-ium | n/a | |
| 41 | P04058_E20 | E20 | DB07701 | 1150567 | CHEMBL107316 | 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE | n/a | Ki(nM) = 3.3 |
| 42 | P04058_E2W | E2W | n/a | 122549007 | n/a | 6-[4-[(7-chloranyl-1,2,3,4-tetrahydroacridin-9-yl)amino]butyl]-2-[(oxidanylamino)methyl]pyridin-3-ol | n/a | |
| 43 | P04058_EBW | EBW | n/a | 1338 | CHEMBL140020 | 4-(5-{4-[DIMETHYL(PROP-2-ENYL)AMMONIO]PHENYL}-3-OXOPENTYL)-N,N-DIMETHYL-N-PROP-2-ENYLBENZENAMINIUM | n/a | |
| 44 | P04058_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 45 | P04058_EDR | EDR | DB01010 | 3202 | CHEMBL1104 | EDROPHONIUM ION | n/a | |
| 46 | P04058_ELT | ELT | n/a | 541907 | n/a | ethoxy-~{N},~{N}-dimethyl-phosphonamidic acid | n/a | |
| 47 | P04058_EMM | EMM | n/a | 445893 | n/a | [METHYL(VINYL)AMINO]METHANOL | n/a | |
| 48 | P04058_ETM | ETM | DB01803 | 37851 | CHEMBL136145 | 2-(TRIMETHYLAMMONIUM)ETHYL THIOL | n/a | IC50(nM) = 440000.0 |
| 49 | P04058_F11 | F11 | n/a | 9549197 | CHEMBL179732 | N,N'-DI-1,2,3,4-TETRAHYDROACRIDIN-9-YLPENTANE-1,5-DIAMINE | n/a | |
| 50 | P04058_FBQ | FBQ | DB07756 | 1723 | n/a | 1-[3-({[(4-AMINO-5-FLUORO-2-METHYLQUINOLIN-3-YL)METHYL]THIO}METHYL)PHENYL]-2,2,2-TRIFLUOROETHANE-1,1-DIOL | n/a | IC50(nM) = 11000.0 |
| 51 | P04058_FJK | FJK | n/a | n/a | n/a | 1-[4-[[1-[2-(1,2,3,4,4~{a},9~{a}-hexahydroacridin-9-ylamino)ethyl]-1,2,3-triazol-4-yl]methoxymethyl]pyridin-2-yl]-3-[(10~{b}~{R})-6-oxidanylidene-2,3,4,10~{b}-tetrahydro-1~{H}-pyrido[2,1-a]isoindol-10-yl]urea | n/a | |
| 52 | P04058_FJN | FJN | n/a | n/a | n/a | [1-[2-(1,2,3,4,4~{a},9~{a}-hexahydroacridin-9-ylamino)ethyl]-1,2,3-triazol-4-yl]methyl-[[2-[[(10~{b}~{S})-6-oxidanylidene-2,3,4,10~{b}-tetrahydro-1~{H}-pyrido[2,1-a]isoindol-10-yl]carbamoylamino]pyridin-4-yl]methyl]-methyl-azanium | n/a | |
| 53 | P04058_FP1 | FP1 | n/a | 49866995 | n/a | N-hydroxy-1-(1-methylpyridin-2(1H)-ylidene)methanamine | n/a | |
| 54 | P04058_FW8 | FW8 | n/a | 138320049 | CHEMBL4443468 | 1-[(10~{b}~{S})-6-oxidanylidene-2,3,4,10~{b}-tetrahydro-1~{H}-pyrido[2,1-a]isoindol-10-yl]-3-[4-[1-[2-(1,2,3,4-tetrahydroacridin-9-ylamino)ethyl]-1,2,3-triazol-4-yl]pyridin-2-yl]urea | n/a | |
| 55 | P04058_FWN | FWN | n/a | 8190 | CHEMBL1900144 | 2-[2-(2-ethoxyethoxy)ethoxy]ethanol | n/a | |
| 56 | P04058_G3X | G3X | n/a | 9887137 | CHEMBL569978 | (4aS,6R,8aS)-3-methoxy-11-(3-piperidin-1-ylpropyl)-5,6,9,10,11,12-hexahydro-4aH-[1]benzofuro[3a,3,2-ef][2]benzazepin-6-ol | n/a | |
| 57 | P04058_G6X | G6X | n/a | 44543644 | n/a | 2-{6-[(4aS,6R,8aS)-6-hydroxy-3-methoxy-5,6,9,10-tetrahydro-4aH-[1]benzofuro[3a,3,2-ef][2]benzazepin-11(12H)-yl]hexyl}-1 ,2-benzisothiazol-3(2H)-one 1,1-dioxide | n/a | |
| 58 | P04058_GB | GB | n/a | 13818 | CHEMBL122938 | METHYLPHOSPHONIC ACID ESTER GROUP | n/a | |
| 59 | P04058_GD8 | GD8 | DB07821 | 46937095;46937096;49867026; | n/a | (1R)-1,2,2-TRIMETHYLPROPYL (S)-METHYLPHOSPHINATE | n/a | |
| 60 | P04058_GL8 | GL8 | DB02673 | 5288394 | CHEMBL490866 | GALANTHAMINE DERIVATIVE | n/a | |
| 61 | P04058_GNT | GNT | DB00674 | 9651 | CHEMBL659 | (-)-GALANTHAMINE | n/a | Ki(nM) = 190.0 IC50(nM) = 360.0 |
| 62 | P04058_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 63 | P04058_GSG | GSG | DB07846 | 74077203 | n/a | 1S,3AS,8AS-TRIMETHYL-1-OXIDO-1,2,3,3A,8,8A-HEXAHYDROPYRROLO[2,3-B]INDOL-5-YL 2-ETHYLPHENYLCARBAMATE | n/a | |
| 64 | P04058_HBP | HBP | n/a | 73155752;135412777;135444708;135998834; | CHEMBL1187858 | 1,7-HEPTYLENE-BIS-N,N'-SYN-2-PYRIDINIUMALDOXIME | n/a | |
| 65 | P04058_HG | HG | n/a | 26623 | n/a | MERCURY (II) ION | n/a | |
| 66 | P04058_HTB | HTB | n/a | 91864546 | CHEMBL3752467 | N-(1-benzofuran-2-ylmethyl)-N'-(1,2,3,4-tetrahydroacridin-9-yl)heptane-1,7-diamine | n/a | |
| 67 | P04058_HUB | HUB | DB03348 | 5462442 | CHEMBL245079 | HUPERZINE B | n/a | |
| 68 | P04058_HUP | HUP | DB04864 | 854026 | CHEMBL395280 | Huperzine A | n/a | Ki(nM) = 175.0 IC50(nM) = 414.0 |
| 69 | P04058_HUX | HUX | DB04114 | 5288588 | CHEMBL483716 | 3-CHLORO-9-ETHYL-6,7,8,9,10,11-HEXAHYDRO-7,11-METHANOCYCLOOCTA[B]QUINOLIN-12-AMINE | n/a | |
| 70 | P04058_IOD | IOD | n/a | 30165 | n/a | IODIDE ION | n/a | |
| 71 | P04058_IUM | IUM | n/a | n/a | n/a | URANYL (VI) ION | n/a | |
| 72 | P04058_JDS | JDS | n/a | 137091337 | n/a | 6-[4-[(7-chloranyl-1,2,3,4-tetrahydroacridin-9-yl)amino]butyl]-2-[(~{Z})-hydroxyiminomethyl]pyridin-3-ol | n/a | |
| 73 | P04058_K | K | n/a | 813 | CHEMBL1233793 | POTASSIUM ION | n/a | |
| 74 | P04058_MBT | MBT | DB08167 | 4139 | CHEMBL191083 | 3,7-BIS(DIMETHYLAMINO)PHENOTHIAZIN-5-IUM | n/a | |
| 75 | P04058_MES | MES | DB03814 | 78165;4478249; | CHEMBL1234276 | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | n/a | |
| 76 | P04058_MF2 | MF2 | DB04021 | 5288799 | n/a | CIS-2,6-DIMETHYLMORPHOLINOOCTYLCARBAMYLESEROLINE | n/a | |
| 77 | P04058_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 78 | P04058_N8T | N8T | n/a | 6540271 | CHEMBL129108 | N-[8-(1,2,3,4-TETRAHYDROACRIDIN-9-YLTHIO)OCTYL]-1,2,3,4-TETRAHYDROACRIDIN-9-AMINE | n/a | |
| 79 | P04058_N9T | N9T | n/a | 71508421 | CHEMBL4648322 | (1~{R},3~{S})-~{N}-(6,7-dimethoxy-2-oxidanylidene-chromen-3-yl)-3-[(phenylmethyl)amino]cyclohexane-1-carboxamide | n/a | |
| 80 | P04058_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 81 | P04058_NAF | NAF | DB03359 | 3991 | n/a | M-(N,N,N-TRIMETHYLAMMONIO)-2,2,2-TRIFLUORO-1,1-DIHYDROXYETHYLBENZENE | n/a | |
| 82 | P04058_NAG | NAG | DB00141 | 24139 | CHEMBL447878 | 2-acetamido-2-deoxy-beta-D-glucopyranose | n/a | |
| 83 | P04058_NHG | NHG | n/a | 56965941 | n/a | BIS-NORESEROLINE | n/a | |
| 84 | P04058_NTJ | NTJ | n/a | n/a | n/a | R-ETHYL N,N-DIMETHYLPHOSPHONAMIDATE | n/a | |
| 85 | P04058_NWA | NWA | n/a | 6914581 | n/a | 4,4-DIHYDROXY-N,N,N-TRIMETHYLPENTAN-1-AMINIUM | n/a | |
| 86 | P04058_OMI | OMI | n/a | 10125067 | n/a | 1-methyl-1,2-dihydro-3H-indol-3-one | n/a | |
| 87 | P04058_P6G | P6G | n/a | 17472 | CHEMBL1235082 | HEXAETHYLENE GLYCOL | n/a | |
| 88 | P04058_PE7 | PE7 | DB02404 | 446506 | n/a | 1-DEOXY-1-THIO-HEPTAETHYLENE GLYCOL | n/a | |
| 89 | P04058_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 90 | P04058_PG4 | PG4 | n/a | 8200 | CHEMBL1235254 | TETRAETHYLENE GLYCOL | n/a | |
| 91 | P04058_PGE | PGE | DB02327 | 8172 | CHEMBL1235259 | TRIETHYLENE GLYCOL | n/a | |
| 92 | P04058_RM0 | RM0 | n/a | 135567430 | n/a | 2-[(~{E})-hydroxyiminomethyl]-6-(5-morpholin-4-ylpentyl)pyridin-3-ol | n/a | |
| 93 | P04058_SAF | SAF | DB04556 | 445892 | n/a | 3-[(1S)-1-(DIMETHYLAMINO)ETHYL]PHENOL | n/a | |
| 94 | P04058_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 95 | P04058_TFL | TFL | DB08615 | 24832019 | n/a | 2-[4-(DIMETHYLAMINO)PHENYL]-6-HYDROXY-3-METHYL-1,3-BENZOTHIAZOL-3-IUM | n/a | |
| 96 | P04058_THA | THA | DB00382 | 1935 | CHEMBL95 | TACRINE | n/a | Ki(nM) = 40.0 IC50(nM) = 8.2 |
| 97 | P04058_TJH | TJH | n/a | 78350462 | CHEMBL3356536 | 2-({2-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]ethyl}amino)-5-hydroxynaphthalene-1,4-dione | n/a | |
| 98 | P04058_TNH | TNH | n/a | 77844972 | n/a | N-[6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexyl]pyridine-3-carboxamide | n/a | |
| 99 | P04058_TRS | TRS | DB03754 | 3777159;88088752;152743085; | n/a | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | n/a | |
| 100 | P04058_UNX | UNX | n/a | |||||
| 101 | P04058_VX | VX | n/a | 449085 | n/a | O-ETHYLMETHYLPHOSPHONIC ACID ESTER GROUP | n/a | |
| 102 | P04058_VXA | VXA | DB02825 | 3396559 | n/a | METHYLPHOSPHONIC ACID ESTER GROUP | n/a | |
| 103 | P04058_XE | XE | n/a | 23991 | CHEMBL1236802 | XENON | n/a | |
| 104 | P04058_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a |