Gene name: GBA1
Protein name: Lysosomal acid glucosylceramidase
List of molecules and drugs that interact with protein P04062
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P04062_3RI | 3RI | n/a | 10584440 | n/a | (3S,4R,5R,6S)-1-(2-hydroxyethyl)azepane-3,4,5,6-tetrol | n/a | |
| 2 | P04062_3RK | 3RK | n/a | 10080697 | CHEMBL13922 | (3S,4R,5R,6S)-azepane-3,4,5,6-tetrol | n/a | |
| 3 | P04062_79B | 79B | n/a | 137348576 | n/a | 11-[(2~{R})-2-[(2-pyridin-3-ylquinazolin-4-yl)amino]-2,3-dihydro-1~{H}-inden-5-yl]undec-10-ynoic acid | n/a | |
| 4 | P04062_7E4 | 7E4 | n/a | 137348597 | n/a | 11-[(2~{S})-2-[(2-pyridin-3-ylquinazolin-4-yl)amino]-2,3-dihydro-1~{H}-inden-5-yl]undec-10-ynoic acid | n/a | |
| 5 | P04062_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 6 | P04062_AMF | AMF | DB07370 | n/a | n/a | (3Z,5S,6R,7S,8R,8aS)-3-(octylimino)hexahydro[1,3]thiazolo[3,4-a]pyridine-5,6,7,8-tetrol | n/a | |
| 7 | P04062_B3P | B3P | DB02676 | 125132 | CHEMBL63859 | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | n/a | |
| 8 | P04062_BTB | BTB | n/a | 81462 | n/a | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | n/a | |
| 9 | P04062_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 10 | P04062_FMT | FMT | DB01942 | 284;18971002; | CHEMBL116736 | FORMIC ACID | n/a | |
| 11 | P04062_GAI | GAI | DB00536 | 3520 | CHEMBL821 | GUANIDINE | n/a | |
| 12 | P04062_GLN | GLN | DB00130 | 5961;6992086; | CHEMBL930 | GLUTAMINE | n/a | |
| 13 | P04062_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 14 | P04062_HK2 | HK2 | n/a | 138753242 | n/a | (1~{S},3~{S},4~{R},6~{R})-2,3,4,6-tetrakis(oxidanyl)-5-[[4-[3-(4-phenylphenoxy)propyl]-1,2,3-triazol-1-yl]methyl]cyclohexan-1-olate | n/a | |
| 15 | P04062_HKW | HKW | n/a | 138753244 | n/a | 6-[3,3-dimethyl-2-[(1~{E},3~{E},5~{E})-5-(1,3,3-trimethylindol-2-ylidene)penta-1,3-dienyl]indol-1-ium-1-yl]-~{N}-[[1-[[(1~{S},2~{R},3~{R},4~{S},6~{S})-2,3,4,6-tetrakis(oxidanyl)cyclohexyl]methyl]-1,2,3-triazol-4-yl]methyl]hexanamide | n/a | |
| 16 | P04062_IFM | IFM | DB04545 | 447607 | CHEMBL206468 | 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE | inhibitor | Ki(nM) = 1.7 IC50(nM) = 8.2 EC50(nM) = 300.0 |
| 17 | P04062_INS | INS | DB13178 | n/a | CHEMBL1222251 | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE | n/a | |
| 18 | P04062_JXA | JXA | n/a | 138403230 | n/a | (2R,3S,4R)-2-{[4-(3,5-dichlorophenyl)-1H-1,2,3-triazol-1-yl]methyl}pyrrolidine-3,4-diol | n/a | |
| 19 | P04062_K | K | n/a | 813 | CHEMBL1233793 | POTASSIUM ION | n/a | |
| 20 | P04062_K35 | K35 | n/a | 137349626 | n/a | ~{N}-[(1~{R},2~{R},3~{R},4~{S},5~{S},6~{S})-2-(hydroxymethyl)-3,4,5,6-tetrakis(oxidanyl)cyclohexyl]pentanamide | n/a | |
| 21 | P04062_LGS | LGS | DB08090 | n/a | n/a | (3Z,5S,6R,7S,8R,8aR)-3-(octylimino)hexahydro[1,3]oxazolo[3,4-a]pyridine-5,6,7,8-tetrol | n/a | |
| 22 | P04062_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 23 | P04062_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 24 | P04062_NAG | NAG | DB00141 | 24139 | CHEMBL447878 | 2-acetamido-2-deoxy-beta-D-glucopyranose | n/a | |
| 25 | P04062_NBV | NBV | DB00419 | 51634 | CHEMBL1029 | (2R,3R,4R,5S)-1-BUTYL-2-(HYDROXYMETHYL)PIPERIDINE-3,4,5-TRIOL | n/a | Ki(nM) = 116000.0 IC50(nM) = 118000.0 |
| 26 | P04062_NDG | NDG | DB03740 | 82313 | CHEMBL1234669 | 2-acetamido-2-deoxy-alpha-D-glucopyranose | inhibitor | |
| 27 | P04062_NF8 | NF8 | n/a | 445257 | n/a | (2~{R},3~{S},4~{S},5~{S})-5-fluoranyl-2-(hydroxymethyl)oxane-3,4-diol | n/a | |
| 28 | P04062_NND | NND | DB08283 | 501640 | CHEMBL408500 | (2R,3R,4R,5S)-2-(HYDROXYMETHYL)-1-NONYLPIPERIDINE-3,4,5-TRIOL | n/a | Ki(nM) = 300.0 IC50(nM) = 300.0 |
| 29 | P04062_PN8 | PN8 | n/a | n/a | n/a | (1~{S},2~{R},3~{R},4~{S},5~{S})-4-[[($l^{5}-azanylidyne-$l^{5}-azanyl)amino]methyl]cyclohexane-1,2,3,5-tetrol | n/a | |
| 30 | P04062_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 31 | P04062_PO8 | PO8 | n/a | 155907495 | n/a | (1~{R},2~{S},3~{S},4~{S},5~{R},6~{R})-5-azanyl-6-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol | n/a | |
| 32 | P04062_Q65 | Q65 | n/a | n/a | n/a | (1~{S},2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[4-[4-[(12~{R})-2,2-bis(fluoranyl)-4,6,10,12-tetramethyl-1,3-diaza-2$l^{4}-boratricyclo[7.3.0.0^{3,7}]dodeca-4,6,9-trien-8-yl]butyl]-1,2,3-triazol-1-yl]methyl]-7-oxabicyclo[4.1.0]heptane-2,3,4-triol | n/a | |
| 33 | P04062_Q68 | Q68 | n/a | 156022750 | n/a | ~{N}-[[1-[[(1~{S},2~{R},3~{R},4~{S},6~{S})-6-(hexylamino)-2,3,4-tris(oxidanyl)cyclohexyl]methyl]-1,2,3-triazol-4-yl]methyl]ethanamide | n/a | |
| 34 | P04062_RJR | RJR | n/a | n/a | n/a | (1~{S},2~{R},3~{R},4~{S},5~{S})-4-[[4-[3-(1-adamantylmethoxy)propyl]-1,2,3-triazol-1-yl]methyl]cyclohexane-1,2,3,5-tetrol | n/a | |
| 35 | P04062_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 36 | P04062_UUE | UUE | n/a | 162679638 | n/a | 8-[4-(1-ethyl-1,2,3-triazol-4-yl)butyl]-2,2-bis(fluoranyl)-4,6,10,12-tetramethyl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.0^{3,7}]dodeca-1(12),4,6,8,10-pentaene | n/a | |
| 37 | P04062_UUH | UUH | n/a | 162679639 | n/a | (1~{S},2~{R},3~{R},4~{S},5~{S})-4-[[4-[4-[2,2-bis(fluoranyl)-4,6,10,12-tetramethyl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.0^{3,7}]dodeca-1(12),4,6,8,10-pentaen-8-yl]butyl]-1,2,3-triazol-1-yl]methyl]cyclohexane-1,2,3,5-tetrol | n/a | |
| 38 | P04062_UUU | UUU | n/a | 126961706 | n/a | (1S,2S,3S,4S,5R,6R)-5-amino-6-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol | n/a | |
| 39 | P04062_2H3 | 2H3 | DB03106 | n/a | CHEMBL468154 | scyllo-inositol | n/a |