P04626 ERBB2_HUMAN
Gene name: ERBB2
Protein name: Receptor tyrosine-protein kinase

List of molecules and drugs that interact with protein P04626

#	DrugDomain Data	PBD ligand	DrugBank Accession	PubChem	ChEMBL	Name	Drug action	Affinity data
1	P04626_03P	03P	n/a	11620908	CHEMBL1614725	N-{2-[4-({3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-5H-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl}-3-hydroxy-3-methylbutanamide	n/a
2	P04626_03Q	03Q	n/a	16736274	CHEMBL1614726	2-{2-[4-({5-chloro-6-[3-(trifluoromethyl)phenoxy]pyridin-3-yl}amino)-5H-pyrrolo[3,2-d]pyrimidin-5-yl]ethoxy}ethanol	n/a
3	P04626_70I	70I	n/a	164575857	n/a	1-[4-[4-[[3,5-bis(chloranyl)-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]amino]pyrimido[5,4-d]pyrimidin-6-yl]piperazin-1-yl]-4-(3-fluoranylazetidin-1-yl)butan-1-one	n/a
4	P04626_CL	CL	n/a	312	n/a	CHLORIDE ION	n/a
5	P04626_GOL	GOL	DB09462	753	CHEMBL692	GLYCEROL	n/a
6	P04626_NAG	NAG	DB00141	24139	CHEMBL447878	2-acetamido-2-deoxy-beta-D-glucopyranose	n/a
7	P04626_VOY	VOY	n/a	155776785	n/a	(2E)-N-[3-cyano-7-ethoxy-4-({3-methyl-4-[([1,2,4]triazolo[1,5-a]pyridin-7-yl)oxy]phenyl}amino)quinolin-6-yl]-4-(dimethylamino)but-2-enamide	n/a
8	P04626_SO4	SO4	DB14546	1117	n/a	SULFATE ION	n/a
9	P04626_FMM	FMM	DB01259	208908	CHEMBL554	Lapatinib	antagonist	IC50(nM) = 2.7 Kd(nM) = 7.0
10	P04626_DB05944	n/a	DB05944	n/a	n/a	Varlitinib	modulator
11	P04626_DB06021	n/a	DB06021	n/a	n/a	AV-412	n/a
12	P04626_0WM	0WM	DB08916	10184653	CHEMBL1173655	Afatinib	inhibitor	IC50(nM) = 0.57 Kd(nM) = 5.0 EC50(nM) = 3.0
13	P04626_DB11652	n/a	DB11652	n/a	n/a	Tucatinib	inhibitor
14	P04626_DB11973	n/a	DB11973	n/a	n/a	Tesevatinib	n/a
15	P04626_2RC	2RC	DB12010	11671467	CHEMBL2103830	Fostamatinib	inhibitor
16	P04626_6GY	6GY	DB12267	68165256	CHEMBL3545311	Brigatinib	inhibitor
17	P04626_DB15035	n/a	DB15035	n/a	n/a	Zanubrutinib	inhibitor