Gene name: TP53
Protein name: Cellular tumor antigen
List of molecules and drugs that interact with protein P04637
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P04637_6SM | 6SM | n/a | 20029396 | n/a | 5-chloranylpyrimidine-4-carboxylic acid | n/a | |
| 2 | P04637_92O | 92O | n/a | 11831189 | CHEMBL5305628 | 7-ethyl-3-(piperidin-4-yl)-1H-indole | n/a | |
| 3 | P04637_9GH | 9GH | n/a | 133082032 | CHEMBL4162051 | 2-(diethylamino)-6-iodanyl-5-oxidanyl-7-pyrrol-1-yl-1,3-benzothiazole-4-carboxylic acid | n/a | |
| 4 | P04637_9GK | 9GK | n/a | 133082030 | CHEMBL4171798 | 3-iodanyl-2-oxidanyl-5-(2-phenylethoxy)-4-pyrrol-1-yl-benzoic acid | n/a | |
| 5 | P04637_9GN | 9GN | n/a | 133082031 | CHEMBL4168439 | 3-iodanyl-2-oxidanyl-5-propylsulfanyl-4-pyrrol-1-yl-benzoic acid | n/a | |
| 6 | P04637_9GQ | 9GQ | n/a | 133082029 | CHEMBL4164612 | 5-butoxy-3-iodanyl-2-oxidanyl-4-pyrrol-1-yl-benzoic acid | n/a | |
| 7 | P04637_9GT | 9GT | n/a | 133082028 | CHEMBL4160123 | 3-iodanyl-2-oxidanyl-5-prop-2-enoxy-4-pyrrol-1-yl-benzoic acid | n/a | |
| 8 | P04637_9GW | 9GW | n/a | 133082027 | CHEMBL4168045 | 3-iodanyl-2-oxidanyl-5-propoxy-4-pyrrol-1-yl-benzoic acid | n/a | |
| 9 | P04637_9GZ | 9GZ | n/a | 133082026 | CHEMBL4168268 | 5-(4-fluorophenyl)-3-iodanyl-2-oxidanyl-4-pyrrol-1-yl-benzoic acid | n/a | |
| 10 | P04637_9H2 | 9H2 | n/a | 133082025 | CHEMBL4172014 | 6-(hydroxymethyl)-2,4-bis(iodanyl)-3-pyrrol-1-yl-phenol | n/a | |
| 11 | P04637_9H5 | 9H5 | n/a | 133082024 | CHEMBL4168664 | [3,5-bis(iodanyl)-2-oxidanyl-4-pyrrol-1-yl-phenyl]-(4-methylpiperazin-1-yl)methanone | n/a | |
| 12 | P04637_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 13 | P04637_ARS | ARS | n/a | 23969 | CHEMBL1231052 | ARSENIC | n/a | |
| 14 | P04637_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 15 | P04637_DTT | DTT | DB04447 | 439196 | CHEMBL406270 | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | n/a | |
| 16 | P04637_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 17 | P04637_EPE | EPE | DB16872 | 23830;23831;3275884; | CHEMBL1232545 | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | n/a | |
| 18 | P04637_EXN | EXN | n/a | 138753187 | n/a | [9-ethyl-7-(furan-2-yl)carbazol-3-yl]methyl-methyl-azanium | n/a | |
| 19 | P04637_EXQ | EXQ | n/a | 138753188 | n/a | [9-ethyl-7-(4-methylthiophen-2-yl)carbazol-3-yl]methyl-methyl-azanium | n/a | |
| 20 | P04637_EY2 | EY2 | n/a | 138753189 | n/a | (7-bromanyl-9-ethyl-carbazol-3-yl)methyl-methyl-azanium | n/a | |
| 21 | P04637_EYB | EYB | n/a | 138753190 | n/a | [9-ethyl-7-(1,2-oxazol-4-yl)carbazol-3-yl]methyl-methyl-azanium | n/a | |
| 22 | P04637_EYE | EYE | n/a | 138753191 | n/a | [9-ethyl-7-(5-methylthiophen-2-yl)carbazol-3-yl]methyl-methyl-azanium | n/a | |
| 23 | P04637_FMT | FMT | DB01942 | 284;18971002; | CHEMBL116736 | FORMIC ACID | n/a | |
| 24 | P04637_FOR | FOR | DB03843 | 712 | CHEMBL1255 | FORMYL GROUP | n/a | |
| 25 | P04637_FY8 | FY8 | n/a | 39869080 | n/a | N-(5-chloranyl-2-oxidanyl-phenyl)piperidine-4-carboxamide | n/a | |
| 26 | P04637_GOH | GOH | n/a | 101043856 | n/a | 5-[2-cyclopropyl-5-(1H-pyrrol-1-yl)-1,3-oxazol-4-yl]-1H-1,2,3,4-tetrazole | n/a | |
| 27 | P04637_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 28 | P04637_IOD | IOD | n/a | 30165 | n/a | IODIDE ION | n/a | |
| 29 | P04637_K | K | n/a | 813 | CHEMBL1233793 | POTASSIUM ION | n/a | |
| 30 | P04637_KMN | KMN | n/a | 91885639 | n/a | 2-[[4-(diethylamino)piperidin-1-yl]methyl]-6-ethynyl-4-(3-phenoxyprop-1-ynyl)phenol | n/a | |
| 31 | P04637_KV0 | KV0 | n/a | 165430649 | n/a | 4-(3-fluoranylpyrrol-1-yl)-3,5-bis(iodanyl)-2-oxidanyl-benzoic acid | n/a | |
| 32 | P04637_KVA | KVA | n/a | 165430650 | n/a | 4-[3,4-bis(fluoranyl)pyrrol-1-yl]-3,5-bis(iodanyl)-2-oxidanyl-benzoic acid | n/a | |
| 33 | P04637_LE9 | LE9 | n/a | 25247475 | CHEMBL5183297 | 4-bromanyl-5-(trifluoromethyl)-1H-pyrazol-3-amine | n/a | |
| 34 | P04637_LEB | LEB | n/a | 145925606 | n/a | 1-[7-bromanyl-9-[2,2,2-tris(fluoranyl)ethyl]carbazol-3-yl]-~{N}-methyl-methanamine | n/a | |
| 35 | P04637_LEK | LEK | n/a | 145925605 | n/a | 1-[9-ethyl-7-(1,3-thiazol-4-yl)carbazol-3-yl]-~{N}-methyl-methanamine | n/a | |
| 36 | P04637_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 37 | P04637_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 38 | P04637_NXG | NXG | n/a | 56844247 | n/a | 2-{[4-(DIETHYLAMINO)PIPERIDIN-1-YL]METHYL}-4-(3-HYDROXYPROP-1-YN-1-YL)-6-IODOPHENOL | n/a | |
| 39 | P04637_O4B | O4B | n/a | 28557 | CHEMBL155204 | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE | n/a | |
| 40 | P04637_O80 | O80 | n/a | 121225435 | n/a | N,N-dimethyl-1-[9-(2,2,2-trifluoroethyl)-9H-carbazol-3-yl]methanamine | n/a | |
| 41 | P04637_O82 | O82 | n/a | 40011822 | n/a | 1-[9-(2-fluoroethyl)-9H-carbazol-3-yl]-N-methylmethanamine | n/a | |
| 42 | P04637_O83 | O83 | n/a | 121225434 | n/a | 1-[9-(2,2-difluoroethyl)-9H-carbazol-3-yl]-N-methylmethanamine | n/a | |
| 43 | P04637_P51 | P51 | n/a | 56844249 | n/a | 2-{[4-(diethylamino)piperidin-1-yl]methyl}-6-iodo-4-(3-phenoxyprop-1-yn-1-yl)phenol | n/a | |
| 44 | P04637_P74 | P74 | n/a | 56844248 | n/a | TERT-BUTYL [3-(3-{[4-(DIETHYLAMINO)PIPERIDIN-1-YL]METHYL}-4-HYDROXY-5-IODOPHENYL)PROP-2-YN-1-YL]CARBAMATE | n/a | |
| 45 | P04637_P83 | P83 | DB08363 | 4722579 | CHEMBL1235116 | 1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine | inhibitor | |
| 46 | P04637_P84 | P84 | n/a | 2845841 | CHEMBL5183726 | 2,4-BIS(IODANYL)-6-[[METHYL-(1-METHYLPIPERIDIN-4-YL)AMINO]METHYL]PHENOL | n/a | |
| 47 | P04637_P86 | P86 | n/a | 56844246 | n/a | 2-{[4-(DIETHYLAMINO)PIPERIDIN-1-YL]METHYL}-4,6-DIIODOPHENOL | n/a | |
| 48 | P04637_P96 | P96 | n/a | 56844250 | CHEMBL4170894 | 2-{[4-(diethylamino)piperidin-1-yl]methyl}-6-iodo-4-[3-(phenylamino)prop-1-yn-1-yl]phenol | n/a | |
| 49 | P04637_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 50 | P04637_PG4 | PG4 | n/a | 8200 | CHEMBL1235254 | TETRAETHYLENE GLYCOL | n/a | |
| 51 | P04637_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 52 | P04637_QC5 | QC5 | n/a | 71306441 | n/a | 2-(4-(4-fluorophenyl)-5-(1H-pyrrol-1-yl)-1H-pyrazol-1-yl)-N,N-dimethylethanamine | n/a | |
| 53 | P04637_QN8 | QN8 | n/a | 93514107 | n/a | (2~{R})-2-methyl-1-azabicyclo[2.2.2]octan-3-one | n/a | |
| 54 | P04637_QNN | QNN | n/a | 93514108 | n/a | (2~{S})-2-methyl-1-azabicyclo[2.2.2]octan-3-one | n/a | |
| 55 | P04637_R3R | R3R | n/a | 154964132 | n/a | 9-propanoyl-9H-carbazole-3-carbaldehyde, bound form | n/a | |
| 56 | P04637_R4F | R4F | n/a | 82113650 | n/a | 1-(2-methylprop-2-enoyl)-1H-indole-3-carbaldehyde, bound form | n/a | |
| 57 | P04637_R4R | R4R | n/a | 165368575 | n/a | 4-[4-(4-methylpiperazin-1-yl)phenyl]-1-(2-methylprop-2-enoyl)-1H-indole-3-carbaldehyde, bound form | n/a | |
| 58 | P04637_R50 | R50 | n/a | 165368576 | n/a | 2-methyl-1-[(4P)-3-methyl-4-(2-methyl-1,2,3,4-tetrahydroisoquinolin-6-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl]prop-2-en-1-one, bound form | n/a | |
| 59 | P04637_RZH | RZH | n/a | 619586 | n/a | 2-(5-BROMO-7-ETHYL-2-METHYL-1H-INDOLE-3-YL)ETHAN-1-AMIN | n/a | |
| 60 | P04637_SB | SB | n/a | 104894 | n/a | ANTIMONY (III) ION | n/a | |
| 61 | P04637_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 62 | P04637_UFV | UFV | n/a | 735785 | n/a | 3-BROMO-5-(TRIFLUOROMETHYL)BENZENE-1,2-DIAMINE | n/a | |
| 63 | P04637_UL7 | UL7 | n/a | 71144900 | CHEMBL2335188 | 1-{1-[(3-bromo-5-chloro-2-hydroxyphenyl)methyl piperidin-4-yl}piperidin-4-ol] | n/a | |
| 64 | P04637_X0U | X0U | n/a | 771615 | CHEMBL1236743 | 6,7-DIHYDRO[1,4]DIOXINO[2,3-F][1,3]BENZOTHIAZOL-2-AMINE | n/a | |
| 65 | P04637_X0V | X0V | n/a | 520822 | CHEMBL1236744 | 4-(TRIFLUOROMETHYL)BENZENE-1,2-DIAMINE | n/a | |
| 66 | P04637_X0W | X0W | n/a | 112829 | n/a | 5,6-DIMETHOXY-2-METHYL-1,3-BENZOTHIAZOLE | n/a | |
| 67 | P04637_Y0V | Y0V | n/a | 101043855 | CHEMBL4165245 | 2-hydroxy-3,5-diiodo-4-(1H-pyrrol-1-yl)benzoic acid | n/a | |
| 68 | P04637_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 69 | P04637_AIN | AIN | DB00945 | 2244 | CHEMBL25 | Acetylsalicylic acid | inducer | |
| 70 | P04637_DB01593 | n/a | DB01593 | n/a | n/a | Zinc | n/a | |
| 71 | P04637_TEN | TEN | DB03347 | 6535 | CHEMBL1236251 | Triethyl phosphate | n/a | |
| 72 | P04637_DB14487 | n/a | DB14487 | n/a | n/a | Zinc acetate | n/a | |
| 73 | P04637_DB14533 | n/a | DB14533 | n/a | n/a | Zinc chloride | chaperone |