Gene name: ARG1
Protein name: Arginase-1 (EC 3.5.3.1)
List of molecules and drugs that interact with protein P05089
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P05089_0IZ | 0IZ | n/a | 156600267 | n/a | 3-[(2~{S},3~{R},4~{R})-4-[[(2~{S})-2-azanyl-3-methyl-butanoyl]amino]-2-carboxy-pyrrolidin-3-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boron | n/a | |
| 2 | P05089_1EC | 1EC | n/a | 71295765 | n/a | [(5R)-5-amino-5-carboxy-8-hydroxyoctyl](trihydroxy)borate(1-) | n/a | |
| 3 | P05089_2AI | 2AI | n/a | 82140 | CHEMBL291627 | 1H-imidazol-2-amine | n/a | |
| 4 | P05089_4U7 | 4U7 | n/a | 53249970 | n/a | [(5S)-5-amino-5-carboxy-6,6-difluorohexyl](trihydroxy)borate(1-) | n/a | |
| 5 | P05089_5AB | 5AB | n/a | 53249969 | n/a | [(5S)-5-amino-5-carboxyhexyl](trihydroxy)borate | n/a | |
| 6 | P05089_6HN | 6HN | n/a | 11680096;44629739; | CHEMBL1230498 | 6-nitro-L-norleucine | n/a | |
| 7 | P05089_ABH | ABH | DB01983 | 444965 | n/a | 2(S)-AMINO-6-BORONOHEXANOIC ACID | n/a | |
| 8 | P05089_B3U | B3U | n/a | 12071049;46888425; | CHEMBL1099167 | 2-amino-L-histidine | n/a | |
| 9 | P05089_BCN | BCN | DB03709 | 8761;5256512; | CHEMBL1231251 | BICINE | n/a | |
| 10 | P05089_CO | CO | n/a | 104729 | n/a | COBALT (II) ION | n/a | |
| 11 | P05089_DMO | DMO | DB03856 | 6992039 | CHEMBL222838 | ALPHA-DIFLUOROMETHYLORNITHINE | n/a | |
| 12 | P05089_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 13 | P05089_EXY | EXY | n/a | 24836829 | n/a | 6-[(2R)-oxiran-2-yl]-L-norleucine | n/a | |
| 14 | P05089_GPA | GPA | n/a | 160635 | CHEMBL20667 | 2-AMINO-3-GUANIDINO-PROPIONIC ACID | n/a | |
| 15 | P05089_HAR | HAR | DB03144 | 123895;25799416; | CHEMBL260629 | N-OMEGA-HYDROXY-L-ARGININE | n/a | |
| 16 | P05089_HEZ | HEZ | DB02210 | 12374 | CHEMBL458616 | HEXANE-1,6-DIOL | n/a | |
| 17 | P05089_LYS | LYS | DB00123 | 641599;5460926;24848423;162317967; | n/a | LYSINE | n/a | |
| 18 | P05089_MN | MN | n/a | 27854 | n/a | MANGANESE (II) ION | n/a | |
| 19 | P05089_MPD | MPD | DB03564 | 5288834 | n/a | (4S)-2-METHYL-2,4-PENTANEDIOL | n/a | |
| 20 | P05089_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 21 | P05089_NI | NI | n/a | 934 | n/a | NICKEL (II) ION | n/a | |
| 22 | P05089_NNH | NNH | DB02381 | 446124;26248652; | CHEMBL1234777 | NOR-N-OMEGA-HYDROXY-L-ARGININE | n/a | IC50(nM) = 450.0 Kd(nM) = 47.0 |
| 23 | P05089_O93 | O93 | n/a | n/a | n/a | 2-[(1~{R},3~{R},4~{S})-3-azanyl-3-carboxy-4-[(dimethylamino)methyl]cyclohexyl]ethyl-$l^{3}-oxidanyl-bis(oxidanyl)boron | n/a | |
| 24 | P05089_ORN | ORN | DB00129 | 6262;88747248; | CHEMBL446143 | L-ornithine | n/a | |
| 25 | P05089_QR1 | QR1 | n/a | 146035926 | n/a | {3-[(3aR,4S,5S,6aR)-5-azaniumyl-5-carboxyoctahydrocyclopenta[c]pyrrol-2-ium-4-yl]propyl}(trihydroxy)borate(1-) | n/a | |
| 26 | P05089_QR4 | QR4 | n/a | 146035927 | n/a | {3-[(3aR,4R,5S,6aR)-4-azaniumyl-4-carboxyoctahydrocyclopenta[b]pyrrol-1-ium-5-yl]propyl}(trihydroxy)borate(1-) | n/a | |
| 27 | P05089_QRA | QRA | n/a | 146027042 | n/a | 3-[(5~{S},7~{S},8~{S})-8-azanyl-8-carboxy-1-azaspiro[4.4]nonan-7-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boranuide | n/a | |
| 28 | P05089_QRJ | QRJ | n/a | 146035928 | n/a | {3-[(5R,7S,8S)-8-azaniumyl-8-carboxy-2-azaspiro[4.4]nonan-2-ium-7-yl]propyl}(trihydroxy)borate(1-) | n/a | |
| 29 | P05089_S2C | S2C | DB03731 | 446122 | n/a | S-2-(BORONOETHYL)-L-CYSTEINE | n/a | |
| 30 | P05089_TSZ | TSZ | n/a | 6583;2723789; | CHEMBL256250 | HYDRAZINECARBOTHIOAMIDE | n/a | |
| 31 | P05089_UKR | UKR | n/a | 512898 | CHEMBL5280882 | 1-{[(3S,4S)-3-({4-[2-(4-fluorobenzene-1-sulfonyl)ethyl]piperidin-1-yl}methyl)-4-(3-fluorophenyl)pyrrolidin-1-yl]methyl}cyclopentane-1-carboxylic acid | n/a | |
| 32 | P05089_UL0 | UL0 | n/a | 166638227 | CHEMBL5271123 | 1-{[(3S,4S)-3-(3-fluorophenyl)-4-{[4-(1,3,4-triethyl-1H-pyrazol-5-yl)piperidin-1-yl]methyl}pyrrolidin-1-yl]methyl}cyclopentane-1-carboxylic acid | n/a | |
| 33 | P05089_VUS | VUS | n/a | 162368335 | n/a | 3-[(3~{a}~{S},4~{S},6~{a}~{R})-4-carboxy-2,3,4,5,6,6~{a}-hexahydro-1~{H}-pyrrolo[2,3-c]pyrrol-3~{a}-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boranuide | n/a | |
| 34 | P05089_VUV | VUV | n/a | 162368336 | n/a | 3-[(2~{S},3~{R})-2-carboxypyrrolidin-3-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boranuide | n/a | |
| 35 | P05089_VUY | VUY | n/a | 156612904 | n/a | 3-[(1~{S},2~{S},5~{R})-2-carboxy-6-thia-3-azabicyclo[3.2.0]heptan-1-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boranuide | n/a | |
| 36 | P05089_VV1 | VV1 | n/a | 162368337 | n/a | 3-[(1~{S},2~{S},5~{R})-2-carboxy-3,6-diazabicyclo[3.2.0]heptan-1-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boranuide | n/a | |
| 37 | P05089_VV4 | VV4 | n/a | 162368338 | n/a | 3-[(1~{R},5~{S},8~{R})-5-carboxy-2,6-diazabicyclo[3.2.1]octan-8-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boranuide | n/a | |
| 38 | P05089_X7A | X7A | n/a | 71295761 | n/a | [(5R)-5-amino-5-carboxy-7-(piperidin-1-yl)heptyl](trihydroxy)borate(1-) | n/a | |
| 39 | P05089_X8A | X8A | n/a | 71295762 | n/a | [(5R)-5-carboxy-5-(methylamino)-7-(piperidin-1-yl)heptyl](trihydroxy)borate(1-) | n/a | |
| 40 | P05089_XC3 | XC3 | n/a | 145946141 | n/a | [(~{E})-3-[(3~{S},4~{R})-4-azanyl-1-[(2~{S})-2-azanylpropanoyl]-4-carboxy-pyrrolidin-3-yl]prop-1-enyl]-tris(oxidanyl)boranium | n/a | |
| 41 | P05089_XFG | XFG | n/a | 156600266 | n/a | 3-[(2~{S},3~{R},4~{R})-4-azanyl-2-carboxy-pyrrolidin-3-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boron | n/a | |
| 42 | P05089_XFP | XFP | n/a | 156600265 | n/a | 3-[(2~{S},3~{R})-2-carboxypiperidin-3-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boranuide | n/a | |
| 43 | P05089_Z70 | Z70 | n/a | 45259048;46888426; | CHEMBL1099168 | (2S)-2-amino-4-(2-amino-1H-imidazol-5-yl)butanoic acid | n/a | |
| 44 | P05089_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 45 | P05089_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 46 | P05089_DIR | DIR | DB02499 | 657087 | n/a | Dinor-N(Omega)-Hydroxy-L-Arginine | n/a | |
| 47 | P05089_SDC | SDC | DB02689 | 448254 | n/a | S-{2-[Amino(Dihydroxy)-Lambda~4~-Sulfanyl]Ethyl}-D-Cysteine | n/a | |
| 48 | P05089_URE | URE | DB03904 | 1176 | CHEMBL985 | Urea | n/a | |
| 49 | P05089_AHI | AHI | DB04197 | 5287648 | n/a | Descarboxy-nor-N(Omega)-Hydroxy-L-Arginine | n/a | |
| 50 | P05089_CME | CME | DB04530 | n/a | n/a | S,S-(2-Hydroxyethyl)Thiocysteine | n/a | |
| 51 | P05089_2BH | 2BH | DB04585 | 657085 | n/a | DEHYDRO-2(S)-AMINO-6-BORONOHEXANOIC ACID | n/a | |
| 52 | P05089_BPE | BPE | DB04648 | n/a | n/a | S-propylamine-L-cysteine | n/a |