Gene name: ITGB3
Protein name: Integrin beta-3 (Platelet
List of molecules and drugs that interact with protein P05106
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P05106_180 | 180 | n/a | 448813 | CHEMBL1229688 | 2-(S)-[N-(3-PYRIDYLSULFONYL)AMINO]-3-[[2-CARBONYL-5-[2-(PIPERIDIN-4-YL)ETHYL]-THIENO[2,3-B]THIOPHENEYL]AMINO]-PROPIONIC ACID | n/a | |
| 2 | P05106_5YB | 5YB | n/a | 132121 | CHEMBL138429 | N-(4-carbamimidoylbenzoyl)-beta-alanyl-L-alpha-aspartyl-L-phenylalanine | n/a | |
| 3 | P05106_AGG | AGG | DB00775 | 60947;40466968; | CHEMBL916 | TIROFIBAN | antagonist | IC50(nM) = 11.0 |
| 4 | P05106_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 5 | P05106_CAC | CAC | n/a | 167250 | n/a | CACODYLATE ION | n/a | |
| 6 | P05106_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 7 | P05106_CLR | CLR | DB04540 | 5997 | CHEMBL112570 | CHOLESTEROL | n/a | |
| 8 | P05106_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 9 | P05106_I1F | I1F | n/a | 9809459 | CHEMBL4078717 | {5-[N-(4-carbamimidoylbenzoyl)-4-nitro-L-phenylalanyl]-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridin-2-yl}acetic acid | n/a | |
| 10 | P05106_I7R | I7R | n/a | n/a | n/a | (4-{[(5S)-3-{4-[(E)-imino(4-methylpiperazin-1-yl)methyl]phenyl}-4,5-dihydro-1,2-oxazol-5-yl]methyl}piperazin-1-yl)acetic acid | n/a | |
| 11 | P05106_IR7 | IR7 | n/a | 9875449 | n/a | (4-{[2-oxo-4-(piperidin-4-yl)piperazin-1-yl]acetyl}phenoxy)acetic acid | n/a | |
| 12 | P05106_JUY | JUY | n/a | 139033898 | n/a | (2S)-2-[(1,3-benzothiazole-2-carbonyl)amino]-4-{[5-(1,8-naphthyridin-2-yl)pentanoyl]amino}butanoic acid | n/a | |
| 13 | P05106_M6K | M6K | n/a | 164885961 | n/a | (4-{[(5S)-3-(4-carbamimidoylphenyl)-4,5-dihydro-1,2-oxazol-5-yl]methyl}piperazin-1-yl)acetic acid | n/a | |
| 14 | P05106_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 15 | P05106_MJX | MJX | n/a | 173614 | CHEMBL36326 | {4-[4-(4-carbamimidoylphenyl)piperazin-1-yl]piperidin-1-yl}acetic acid | n/a | |
| 16 | P05106_MN | MN | n/a | 27854 | n/a | MANGANESE (II) ION | n/a | |
| 17 | P05106_MV8 | MV8 | n/a | 9950809 | n/a | (4-{[(5R)-3-(4-carbamimidoylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}piperazin-1-yl)acetic acid | n/a | |
| 18 | P05106_MWI | MWI | n/a | 80274 | CHEMBL356301 | Lotrafiban | n/a | |
| 19 | P05106_MWO | MWO | n/a | 164885963 | n/a | (4-{[(5S)-3-(piperidin-4-yl)-4,5-dihydro-1,2-oxazol-5-yl]methyl}piperazin-1-yl)acetic acid | n/a | |
| 20 | P05106_MWX | MWX | DB06472 | 66000 | CHEMBL3085474 | Fradafiban | modulator | |
| 21 | P05106_N9U | N9U | n/a | 177231 | CHEMBL23743 | Roxifiban | n/a | |
| 22 | P05106_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 23 | P05106_NAG | NAG | DB00141 | 24139 | CHEMBL447878 | 2-acetamido-2-deoxy-beta-D-glucopyranose | n/a | |
| 24 | P05106_NB9 | NB9 | n/a | 3038484 | CHEMBL108111 | Lamifiban | n/a | |
| 25 | P05106_NIF | NIF | n/a | 756604 | CHEMBL1234739 | 2-ethyl-7-piperazin-1-yl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one | n/a | |
| 26 | P05106_NJ9 | NJ9 | n/a | 70344161 | n/a | 3-(4-{[(5S)-3-(4-carbamimidoylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}piperazin-1-yl)propanoic acid | n/a | |
| 27 | P05106_NJF | NJF | n/a | 164885967 | n/a | (1-{[(5S)-3-(4-carbamimidoylphenyl)-4,5-dihydro-1,2-oxazol-5-yl]methyl}piperidin-4-yl)acetic acid | n/a | |
| 28 | P05106_RC2 | RC2 | n/a | 44820665 | CHEMBL1472460 | N-{3-[5-oxo-7-(piperazin-1-yl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl]phenyl}glycinamide | n/a | |
| 29 | P05106_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 30 | P05106_XQS | XQS | n/a | 9907685 | CHEMBL65267 | sibrafiban (active form) | n/a | |
| 31 | P05106_T44 | T44 | DB00451 | 5819;25201348; | CHEMBL1624 | Levothyroxine | binder | |
| 32 | P05106_STL | STL | DB02709 | 445154 | CHEMBL165 | Resveratrol | n/a | |
| 33 | P05106_DB04863 | n/a | DB04863 | n/a | n/a | Lefradafiban | modulator | |
| 34 | P05106_DB15598 | n/a | DB15598 | n/a | n/a | Ferric maltol | substrate |