Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
P06276 CHLE_HUMAN
Gene name: BCHE
Protein name: Cholinesterase (EC 3.1.1.8)

List of molecules and drugs that interact with protein P06276

# DrugDomain Data PBD ligand DrugBank Accession PubChem ChEMBL Name Drug action Affinity data
1 P06276_15F 15F n/a n/a n/a 1-BENZYL-4-({[(1E)-2,2,2-TRICHLOROETHANIMIDOYL]OXY}METHYL)PYRIDINIUM n/a
2 P06276_1PG 1PG DB02042 90255 CHEMBL1229767 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL n/a
3 P06276_3F9 3F9 n/a 25396473 CHEMBL3338394 N-{[(3R)-1-(2,3-dihydro-1H-inden-2-yl)piperidin-3-yl]methyl}-N-(2-methoxyethyl)naphthalene-2-carboxamide n/a
4 P06276_40V 40V n/a 91810430 n/a N-{[(3R)-1-(2,3-dihydro-1H-inden-2-yl)piperidin-3-yl]methyl}-8-hydroxy-N-(2-methoxyethyl)-5-nitroquinoline-7-carboxamide n/a
5 P06276_4OJ 4OJ n/a 12241336 n/a (2-methylphenyl) dihydrogen phosphate n/a
6 P06276_5HB 5HB n/a 122172815 n/a N-{[(3R)-1-benzylpiperidin-3-yl]methyl}-N-methylnaphthalene-2-sulfonamide n/a
7 P06276_5HF 5HF n/a 123133730 n/a N-{[(3S)-1-benzylpiperidin-3-yl]methyl}-N-(2-methoxyethyl)naphthalene-2-sulfonamide n/a
8 P06276_5HH 5HH n/a 123133732 n/a N-{[(3R)-1-benzylpiperidin-3-yl]methyl}naphthalene-2-sulfonamide n/a
9 P06276_6QS 6QS n/a 1043408 n/a [(2~{R})-oxolan-2-yl]methyl 4-(9-ethylcarbazol-3-yl)-2-methyl-5-oxidanylidene-4,6,7,8-tetrahydro-1~{H}-quinoline-3-carboxylate n/a
10 P06276_6YC 6YC n/a 122706715 n/a ~{N}-(2-methoxyethyl)-~{N}-[[(3~{S})-1-prop-2-ynylpiperidin-3-yl]methyl]naphthalene-2-carboxamide n/a
11 P06276_8IS 8IS n/a 165430605 CHEMBL5421371 N-[(2S)-3-(cyclohexylmethylamino)-2-oxidanyl-propyl]-2,2-diphenyl-ethanamide n/a
12 P06276_8IV 8IV n/a 165430606 CHEMBL5439275 N-[(2R)-3-(cyclohexylmethylamino)-2-oxidanyl-propyl]-2,2-diphenyl-ethanamide n/a
13 P06276_8U2 8U2 n/a n/a n/a 2-{1-[4-(12-Amino-3-chloro-6,7,10,11-tetrahydro-7,11-methanocycloocta[b]quinolin-9-yl)butyl]-1H-1,2,3-triazol-4-yl}-N-[4-hydroxy-3-methoxybenzyl]acetamide n/a
14 P06276_8UW 8UW n/a 165430608 CHEMBL5433771 N-[(2R)-3-(cyclohexylmethylamino)-2-oxidanyl-propyl]-3,3-diphenyl-propanamide n/a
15 P06276_92H 92H n/a 132471735 n/a ~{N}-[[(3~{R})-1-(2,3-dihydro-1~{H}-inden-2-yl)piperidin-3-yl]methyl]-~{N}-[2-(dimethylamino)ethyl]naphthalene-2-carboxamide n/a
16 P06276_9A5 9A5 n/a 134129088 CHEMBL4596071 (2~{S})-2-azanyl-~{N}-[6-[(6-chloranyl-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl]-3-(1~{H}-indol-3-yl)propanamide n/a
17 P06276_9CI 9CI n/a 165430612 CHEMBL5396685 N-[(2S)-3-(cyclohexylmethylamino)-2-oxidanyl-propyl]-3,3-diphenyl-propanamide n/a
18 P06276_A87 A87 n/a 162639684 CHEMBL5189102 3-[2-[butyl(2-cycloheptylethyl)amino]ethyl]-1~{H}-indol-6-ol n/a
19 P06276_AI0 AI0 n/a n/a n/a 1-(8-oxidanylquinolin-2-yl)-N-(phenylmethyl)methanimine oxide n/a
20 P06276_AI6 AI6 n/a 165430620 n/a N-tert-butyl-1-[8-[3-(4-prop-2-ynylpiperazin-1-yl)propoxy]quinolin-2-yl]methanimine oxide n/a
21 P06276_BAL BAL DB03107 239;4755801; CHEMBL297569 BETA-ALANINE n/a
22 P06276_BCH BCH DB04250 20689 CHEMBL139908 2-(BUTYRYLSULFANYL)-N,N,N-TRIMETHYLETHANAMINIUM substrate
23 P06276_BEZ BEZ DB03793 243;20144841; CHEMBL541 BENZOIC ACID n/a
24 P06276_BR BR n/a 259 n/a BROMIDE ION n/a
25 P06276_BUA BUA DB03568 264 CHEMBL14227 butanoic acid inhibitor
26 P06276_BUW BUW n/a 688098 n/a R-ethopropazine n/a
27 P06276_BY2 BY2 n/a 134823960 n/a [3-[(1~{R})-1-(dimethylamino)ethyl]-4-oxidanyl-phenyl] ~{N}-ethyl-~{N}-methyl-carbamate n/a
28 P06276_C0I C0I n/a 166175723 n/a (3~{S})-1-[[4-[2-(1~{H}-indol-3-yl)ethylcarbamoyl]phenyl]methyl]-~{N}-[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]piperidine-3-carboxamide n/a
29 P06276_C4I C4I n/a 166174527 n/a (3~{S})-1-[[4-(naphthalen-1-ylcarbamoyl)phenyl]methyl]-~{N}-[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]piperidine-3-carboxamide n/a
30 P06276_CA CA n/a 271 n/a CALCIUM ION n/a
31 P06276_CHT CHT DB00122 305 CHEMBL920 CHOLINE ION product of
32 P06276_CL CL n/a 312 n/a CHLORIDE ION n/a
33 P06276_CVX CVX n/a 12459492 n/a O-BUTLYLMETHYLPHOSPHONIC ACID ESTER GROUP n/a
34 P06276_CWQ CWQ n/a 137349136 n/a 2-[[(3~{R})-1-(2,3-dihydro-1~{H}-inden-2-yl)piperidin-3-yl]methyl-(8-oxidanylquinolin-2-yl)carbonyl-amino]ethyl-dimethyl-azanium n/a
35 P06276_DEP DEP DB02811 220224 n/a DIETHYL PHOSPHONATE inhibitor
36 P06276_DME DME DB01245 2968 CHEMBL1190 DECAMETHONIUM ION n/a
37 P06276_DMS DMS DB01093 679 CHEMBL504 DIMETHYL SULFOXIDE n/a
38 P06276_EDO EDO n/a 174 CHEMBL457299 1,2-ETHANEDIOL n/a
39 P06276_EFS EFS DB03822 74190 n/a ETHYL DIHYDROGEN PHOSPHATE inhibitor
40 P06276_F F n/a 28179 n/a FLUORIDE ION n/a
41 P06276_FP1 FP1 n/a 49866995 n/a N-hydroxy-1-(1-methylpyridin-2(1H)-ylidene)methanamine n/a
42 P06276_FPK FPK n/a 12461843 n/a 1-formyl-L-proline n/a
43 P06276_FUC FUC DB04473 439554 CHEMBL1232862 alpha-L-fucopyranose n/a
44 P06276_FUL FUL DB03283 444863 CHEMBL1230861 beta-L-fucopyranose n/a
45 P06276_GLY GLY DB00145 750;5257127; CHEMBL773 GLYCINE n/a
46 P06276_GOA GOA DB03085 757;3698251; CHEMBL252557 GLYCOLIC ACID n/a
47 P06276_GOL GOL DB09462 753 CHEMBL692 GLYCEROL n/a
48 P06276_GZ5 GZ5 n/a 137552743 CHEMBL4596195 (2~{R})-2-azanyl-~{N}-[6-[(6-chloranyl-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl]-3-(1~{H}-indol-3-yl)propanamide n/a
49 P06276_H19 H19 n/a 137349474 n/a huprine 19 n/a
50 P06276_HG HG n/a 26623 n/a MERCURY (II) ION n/a
51 P06276_HUK HUK n/a 138753254 n/a butyl-[(2~{S})-1-[2-cycloheptylethyl(methyl)azaniumyl]-3-(1~{H}-indol-3-yl)propan-2-yl]-methyl-azanium n/a
52 P06276_HUN HUN n/a 138753255 n/a butyl-[(2~{S})-1-(2-cycloheptylethylamino)-3-(1~{H}-indol-3-yl)-1-oxidanylidene-propan-2-yl]azanium n/a
53 P06276_HUQ HUQ n/a 138753257 n/a butyl-[(2~{S})-1-(2-cycloheptylethylamino)-3-(1~{H}-indol-3-yl)-1-oxidanylidene-propan-2-yl]-dimethyl-azanium n/a
54 P06276_HUT HUT n/a 138753258 n/a (2~{S})-2-(butylamino)-~{N}-(3-cycloheptylpropyl)-3-(1~{H}-indol-3-yl)propanamide n/a
55 P06276_HUZ HUZ n/a n/a n/a (2~{S})-2-(butylamino)-~{N}-[2-[4-(dimethylamino)cyclohexyl]ethyl]-3-(1~{H}-indol-3-yl)propanamide n/a
56 P06276_IA4 IA4 n/a 162639683 CHEMBL5182671 ~{N}-(2-cycloheptylethyl)-2-(1~{H}-indol-3-yl)-~{N}-methyl-ethanamine n/a
57 P06276_ISP ISP DB03976 15391 CHEMBL144888 PHOSPHORYLISOPROPANE n/a
58 P06276_JS0 JS0 n/a 166513889 n/a [8-[3-(4-prop-2-ynylpiperazin-1-yl)propoxy]quinolin-2-yl]methanol n/a
59 P06276_JU5 JU5 n/a 145946024 n/a ~{N}-[[(3~{S})-1-[[2-[7-(diethylamino)-2-oxidanylidene-chromen-3-yl]-1,3-thiazol-4-yl]methyl]piperidin-3-yl]methyl]-~{N}-[2-(dimethylamino)ethyl]naphthalene-2-carboxamide n/a
60 P06276_JUB JUB n/a n/a n/a [7-[4-[2-[naphthalen-2-ylsulfonyl-[[(3~{S})-1-(phenylmethyl)piperidin-1-ium-3-yl]methyl]amino]ethyl]piperazin-4-ium-1-yl]-2,1,3-benzoxadiazol-4-yl]-oxidanyl-oxidanylidene-azanium n/a
61 P06276_K K n/a 813 CHEMBL1233793 POTASSIUM ION n/a
62 P06276_KJT KJT n/a n/a n/a diethyl-[6-[[2-[2-[2-[naphthalen-2-ylsulfonyl-[[(3~{R})-1-(phenylmethyl)piperidin-3-yl]methyl]amino]ethoxy]ethoxy]ethylamino]-oxidanyl-methyl]-7-oxidanylidene-1,3,4,4~{a},5,6,8,8~{a}-octahydronaphthalen-2-ylidene]azanium n/a
63 P06276_L3H L3H n/a 146035902 n/a [(3~{S})-1-(2,3-dihydro-1~{H}-inden-2-yl)piperidin-1-ium-3-yl] ~{N}-phenylcarbamate n/a
64 P06276_LEA LEA DB02406 7991 CHEMBL268736 PENTANOIC ACID n/a
65 P06276_LWL LWL n/a 101524264;117061078;137320192; n/a N,N,N-trimethyl-2-oxo-2-(2-(pyridin-2-ylmethylene)hydrazineyl)ethan-1-aminium n/a
66 P06276_M8X M8X n/a 166513893 CHEMBL5408499 3-[[2-cycloheptylethyl(methyl)amino]methyl]-1~{H}-indol-7-ol n/a
67 P06276_MES MES DB03814 78165;4478249; CHEMBL1234276 2-(N-MORPHOLINO)-ETHANESULFONIC ACID inhibitor
68 P06276_MF5 MF5 n/a 60147027 n/a 1-(1-methylpyridin-1-ium-2-yl)-N-[[2,3,4,5,6-pentakis(fluoranyl)phenyl]methoxy]methanimine n/a
69 P06276_MG MG n/a 888 n/a MAGNESIUM ION n/a
70 P06276_MOH MOH n/a 887 CHEMBL14688 METHANOL n/a
71 P06276_MXB MXB n/a 155801589 n/a (R,E)-2-(hydroxyimino)-N-(3-(4-((2-methyl-1H-imidazol-1-yl)methyl)-1H-1,2,3-triazol-1-yl)-1-phenylpropyl)acetamide n/a
72 P06276_MXK MXK n/a 146675147 n/a (2~{E})-2-hydroxyimino-~{N}-[(1~{S})-3-[4-[(2-methylimidazol-1-yl)methyl]-1,2,3-triazol-1-yl]-1-phenyl-propyl]ethanamid e n/a
73 P06276_N0C N0C n/a 168451667 n/a ~{N}-[(~{E})-[2-phenyl-6-[[2-[2-(trimethyl-$l^{4}-azanyl)ethanoyl]hydrazinyl]methyl]pyrimidin-4-yl]methylideneamino]-2-(trimethyl-$l^{4}-azanyl)ethanamide n/a
74 P06276_NA NA n/a 923 n/a SODIUM ION n/a
75 P06276_NAG NAG DB00141 24139 CHEMBL447878 2-acetamido-2-deoxy-beta-D-glucopyranose n/a
76 P06276_NH4 NH4 n/a 223;16741146; n/a AMMONIUM ION n/a
77 P06276_O0Z O0Z n/a 154815643 n/a (2~{S})-2-(butylamino)-3-(1~{H}-indol-3-yl)-~{N}-[2-[(4~{R})-1-(phenylmethyl)azepan-4-yl]ethyl]propanamide n/a
78 P06276_PEG PEG n/a 8117 CHEMBL1235226 DI(HYDROXYETHYL)ETHER n/a
79 P06276_PG4 PG4 n/a 8200 CHEMBL1235254 TETRAETHYLENE GLYCOL n/a
80 P06276_PGE PGE DB02327 8172 CHEMBL1235259 TRIETHYLENE GLYCOL n/a
81 P06276_PO4 PO4 DB14523 1061 n/a PHOSPHATE ION n/a
82 P06276_PPI PPI DB03766 1032 CHEMBL14021 PROPANOIC ACID n/a
83 P06276_PRM PRM DB02166 4939;101643283; CHEMBL332935 3,8-DIAMINO-5[3-(DIETHYLMETHYLAMMONIO)PROPYL]-6-PHENYLPHENANTHRIDINIUM n/a
84 P06276_QRH QRH n/a n/a n/a (2~{E},4~{E})-5-(1,3-benzodioxol-5-yl)-~{N}-[6-(triphenyl-$l^{5}-phosphanyl)hexyl]penta-2,4-dienamide n/a
85 P06276_RNZ RNZ n/a 155923722 n/a 2,2-dimethylpropyl-[(2~{R},3~{S})-3-(2,2-diphenylethanoylamino)-2-oxidanyl-4-phenyl-butyl]azanium n/a
86 P06276_S6Q S6Q n/a 44389529 CHEMBL368698 ~{N}-(phenylmethyl)-2-[1-(phenylsulfonyl)indol-4-yl]oxy-ethanamine n/a
87 P06276_S78 S78 n/a 156600312 n/a 2-((1-benzyl-1H-indol-4-yl)oxy)-N-((1-(tert-butoxycarbonyl)piperidin-3-yl)methyl)ethan-1-aminium n/a
88 P06276_S8K S8K n/a 156600252 n/a ~{tert}-butyl (3~{S})-3-[[2-[1-(phenylsulfonyl)indol-4-yl]oxyethylamino]methyl]piperidine-1-carboxylate n/a
89 P06276_SIA SIA DB03721 444885 CHEMBL1234621 N-acetyl-alpha-neuraminic acid n/a
90 P06276_SO4 SO4 DB14546 1117 n/a SULFATE ION n/a
91 P06276_TC3 TC3 n/a 20842965 n/a ETHYL HYDROGEN METHYLAMIDOPHOSPHATE n/a
92 P06276_TC5 TC5 n/a 25271564 n/a ETHYL HYDROGEN PROPYLAMIDOPHOSPHATE n/a
93 P06276_TCX TCX n/a 13511151 CHEMBL38354 ethylphosphoramidic acid n/a
94 P06276_TFX TFX n/a 16954 CHEMBL57267 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium n/a
95 P06276_THA THA DB00382 1935 CHEMBL95 TACRINE inhibitor Ki(nM) = 7.0
IC50(nM) = 0.0267
96 P06276_TKN TKN n/a 155923726 n/a methyl 2-methoxy-6-[(~{E})-8-(1,2,3,4-tetrahydroacridin-9-ylamino)oct-6-enyl]benzoate n/a
97 P06276_TN6 TN6 n/a 21872818 n/a diethylphosphoramidic acid n/a
98 P06276_TN7 TN7 n/a 20842990 n/a ethyl hydrogen ethylamidophosphate n/a
99 P06276_TUN TUN DB08658 15083623 n/a ETHYL HYDROGEN DIETHYLAMIDOPHOSPHATE inhibitor
100 P06276_UNL UNL n/a
101 P06276_UNX UNX n/a
102 P06276_VR VR n/a 15764431 n/a 2-METHYLPROPYL HYDROGEN (R)-METHYLPHOSPHONATE n/a
103 P06276_VX VX n/a 449085 n/a O-ETHYLMETHYLPHOSPHONIC ACID ESTER GROUP n/a
104 P06276_VXA VXA DB02825 3396559 n/a METHYLPHOSPHONIC ACID ESTER GROUP n/a
105 P06276_XB8 XB8 n/a 168300967 CHEMBL5402537 ~{N}-[3-(2-fluorophenyl)propyl]-~{N}-[(3-methoxy-2-phenylmethoxy-phenyl)methyl]cyclobutanamine n/a
106 P06276_ZN ZN n/a 32051 CHEMBL1236970 ZINC ION n/a
107 P06276_DB00449 n/a DB00449 n/a n/a Dipivefrin substrate
108 P06276_DB00545 n/a DB00545 n/a n/a Pyridostigmine inhibitor Ki(nM) = 3500.0
IC50(nM) = 900.0
109 P06276_GNT GNT DB00674 9651 CHEMBL659 Galantamine inhibitor Ki(nM) = 192.0
IC50(nM) = 170.0
110 P06276_DB00677 n/a DB00677 n/a n/a Isoflurophate inhibitor
111 P06276_DB00733 n/a DB00733 n/a n/a Pralidoxime activator Ki(nM) = 390000.0
112 P06276_DB00772 n/a DB00772 n/a n/a Malathion inhibitor
113 P06276_DB00843 n/a DB00843 n/a n/a Donepezil inducer Ki(nM) = 640.0
IC50(nM) = 14.0
114 P06276_DB00941 n/a DB00941 n/a n/a Hexafluronium inhibitor
115 P06276_DB00944 n/a DB00944 n/a n/a Demecarium inhibitor
116 P06276_DB00989 n/a DB00989 n/a n/a Rivastigmine inhibitor IC50(nM) = 14.0
117 P06276_EDR EDR DB01010 3202 CHEMBL1104 Edrophonium inhibitor Ki(nM) = 198000.0
IC50(nM) = 1370000.0
118 P06276_DB01057 n/a DB01057 n/a n/a Echothiophate inhibitor
119 P06276_DB01221 n/a DB01221 n/a n/a Ketamine inhibitor
120 P06276_DB01226 n/a DB01226 n/a n/a Mivacurium n/a
121 P06276_DB01408 n/a DB01408 n/a n/a Bambuterol inhibitor
122 P06276_DB02845 n/a DB02845 n/a n/a Methylphosphinic Acid inhibitor
123 P06276_760 760 DB03672 1933 CHEMBL215344 9-N-Phenylmethylamino-Tacrine inhibitor IC50(nM) = 400.0
124 P06276_DB04892 n/a DB04892 n/a n/a Phenserine inhibitor IC50(nM) = 1300.0
125 P06276_DSC DSC DB07681 3383616 n/a DODECANESULFONATE ION inhibitor
126 P06276_I40 I40 DB07940 448167 n/a 9-(3-IODOBENZYLAMINO)-1,2,3,4-TETRAHYDROACRIDINE inhibitor
127 P06276_MPA MPA DB08200 446980 n/a (1R)-menthyl hexyl phosphonate group inhibitor
128 P06276_MPC MPC DB08201 446981 n/a (1S)-menthyl hexyl phosphonate group inhibitor
129 P06276_DB11397 n/a DB11397 n/a n/a Dichlorvos n/a
130 P06276_DB14006 n/a DB14006 n/a n/a Choline salicylate product of