P06493 CDK1_HUMAN
Gene name: CDK1
Protein name: Cyclin-dependent kinase 1

List of molecules and drugs that interact with protein P06493

# DrugDomain Data PBD ligand DrugBank Accession PubChem ChEMBL Name Drug action Affinity data
1 P06493_1QK 1QK n/a 135211563 n/a 3-[({3-ethyl-5-[(2S)-2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl}amino)methyl]-1-hydroxypyridinium n/a
2 P06493_4SP 4SP DB07126 4566 CHEMBL319467 O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE n/a
3 P06493_F9Z F9Z n/a 6602328 CHEMBL1709089 2-(2-chlorophenyl)-8-[(3~{R},4~{R})-1-methyl-3-oxidanyl-piperidin-4-yl]-5,7-bis(oxidanyl)chromen-4-one n/a
4 P06493_FB8 FB8 n/a 16747683 CHEMBL488436 4-(2-methyl-3-propan-2-yl-imidazol-4-yl)-~{N}-(4-methylsulfonylphenyl)pyrimidin-2-amine n/a
5 P06493_FC8 FC8 n/a 2794188 CHEMBL367625 ~{N}2-[(1~{R},2~{S})-2-azanylcyclohexyl]-~{N}6-(3-chlorophenyl)-9-ethyl-purine-2,6-diamine n/a
6 P06493_LZ9 LZ9 DB08138 24864079 CHEMBL518383 {[(2,6-difluorophenyl)carbonyl]amino}-N-(4-fluorophenyl)-1H-pyrazole-3-carboxamide n/a IC50(nM) = 10.0
7 P06493_MPD MPD DB03564 5288834 n/a (4S)-2-METHYL-2,4-PENTANEDIOL n/a
8 P06493_IXM IXM DB02052 n/a CHEMBL216543 Indirubin-3'-monoxime binder
9 P06493_OLO OLO DB02116 4592 CHEMBL280074 Olomoucine binder IC50(nM) = 6000.0
10 P06493_HMD HMD DB02950 17754027;139031112; n/a Hymenialdisine n/a
11 P06493_SU9 SU9 DB03428 5289419 CHEMBL258805 SU9516 binder
12 P06493_CPB CPB DB03496 5287969 CHEMBL428690 Alvocidib n/a Ki(nM) = 40.0
IC50(nM) = 10.0
13 P06493_ATU ATU DB04014 5005498 CHEMBL50894 Alsterpaullone inhibitor IC50(nM) = 35.0
14 P06493_RRC RRC DB06195 160355 CHEMBL14762 Seliciclib inhibitor
15 P06493_LZE LZE DB08142 11338033 CHEMBL445813 AT-7519 n/a Ki(nM) = 190.0
IC50(nM) = 10.0
16 P06493_2RC 2RC DB12010 11671467 CHEMBL2103830 Fostamatinib inhibitor
17 P06493_DB16652 n/a DB16652 n/a n/a Avotaciclib inhibitor