Gene name: CDK1
Protein name: Cyclin-dependent kinase 1
List of molecules and drugs that interact with protein P06493
# | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
---|---|---|---|---|---|---|---|---|
1 | P06493_1QK | 1QK | n/a | 135211563 | n/a | 3-[({3-ethyl-5-[(2S)-2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl}amino)methyl]-1-hydroxypyridinium | n/a | |
2 | P06493_4SP | 4SP | DB07126 | 4566 | CHEMBL319467 | O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE | n/a | |
3 | P06493_F9Z | F9Z | n/a | 6602328 | CHEMBL1709089 | 2-(2-chlorophenyl)-8-[(3~{R},4~{R})-1-methyl-3-oxidanyl-piperidin-4-yl]-5,7-bis(oxidanyl)chromen-4-one | n/a | |
4 | P06493_FB8 | FB8 | n/a | 16747683 | CHEMBL488436 | 4-(2-methyl-3-propan-2-yl-imidazol-4-yl)-~{N}-(4-methylsulfonylphenyl)pyrimidin-2-amine | n/a | |
5 | P06493_FC8 | FC8 | n/a | 2794188 | CHEMBL367625 | ~{N}2-[(1~{R},2~{S})-2-azanylcyclohexyl]-~{N}6-(3-chlorophenyl)-9-ethyl-purine-2,6-diamine | n/a | |
6 | P06493_LZ9 | LZ9 | DB08138 | 24864079 | CHEMBL518383 | {[(2,6-difluorophenyl)carbonyl]amino}-N-(4-fluorophenyl)-1H-pyrazole-3-carboxamide | n/a | IC50(nM) = 10.0 |
7 | P06493_MPD | MPD | DB03564 | 5288834 | n/a | (4S)-2-METHYL-2,4-PENTANEDIOL | n/a | |
8 | P06493_IXM | IXM | DB02052 | n/a | CHEMBL216543 | Indirubin-3'-monoxime | binder | |
9 | P06493_OLO | OLO | DB02116 | 4592 | CHEMBL280074 | Olomoucine | binder | IC50(nM) = 6000.0 |
10 | P06493_HMD | HMD | DB02950 | 17754027;139031112; | n/a | Hymenialdisine | n/a | |
11 | P06493_SU9 | SU9 | DB03428 | 5289419 | CHEMBL258805 | SU9516 | binder | |
12 | P06493_CPB | CPB | DB03496 | 5287969 | CHEMBL428690 | Alvocidib | n/a | Ki(nM) = 40.0 IC50(nM) = 10.0 |
13 | P06493_ATU | ATU | DB04014 | 5005498 | CHEMBL50894 | Alsterpaullone | inhibitor | IC50(nM) = 35.0 |
14 | P06493_RRC | RRC | DB06195 | 160355 | CHEMBL14762 | Seliciclib | inhibitor | |
15 | P06493_LZE | LZE | DB08142 | 11338033 | CHEMBL445813 | AT-7519 | n/a | Ki(nM) = 190.0 IC50(nM) = 10.0 |
16 | P06493_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor | |
17 | P06493_DB16652 | n/a | DB16652 | n/a | n/a | Avotaciclib | inhibitor |