Gene name: CSF1R
Protein name: Macrophage colony-stimulating factor
List of molecules and drugs that interact with protein P07333
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P07333_5CN | 5CN | DB07167 | 9884318 | CHEMBL400754 | 5-CYANO-FURAN-2-CARBOXYLIC ACID [5-HYDROXYMETHYL-2-(4-METHYL-PIPERIDIN-1-YL)-PHENYL]-AMIDE | n/a | IC50(nM) = 24.0 |
| 2 | P07333_622 | 622 | n/a | 52936034 | CHEMBL3639728 | 6-fluoro-N-[(5-fluoro-2-methoxypyridin-3-yl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]pyridin-2-amine | n/a | |
| 3 | P07333_64M | 64M | n/a | 59593266 | CHEMBL4226338 | 5-[(5-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-[4-(trifluoromethyl)benzyl]pyridin-2-amine | n/a | |
| 4 | P07333_6C3 | 6C3 | DB07202 | 135457822 | CHEMBL257705 | 6-CHLORO-3-(3-METHYLISOXAZOL-5-YL)-4-PHENYLQUINOLIN-2(1H)-ONE | n/a | IC50(nM) = 140.0 |
| 5 | P07333_8C5 | 8C5 | n/a | 24938241 | CHEMBL490080 | 8-cyclohexyl-N-methoxy-5-oxo-2-{[4-(2-pyrrolidin-1-ylethyl)phenyl]amino}-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide | n/a | |
| 6 | P07333_A7O | A7O | n/a | 49806372 | CHEMBL4474690 | (3-{4-[(4-cyclopropylphenyl)methoxy]-3-methoxyphenyl}azetidin-1-yl)(4-{[(2S)-2,3-dihydroxypropoxy]methyl}pyridin-2-yl)methanone | n/a | |
| 7 | P07333_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 8 | P07333_BDY | BDY | n/a | 44631856 | n/a | N~3~-(2,6-dichlorobenzyl)-5-(4-{[(2R)-2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]carbonyl}phenyl)pyrazine-2,3-diamine | n/a | |
| 9 | P07333_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 10 | P07333_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 11 | P07333_I9W | I9W | n/a | 86270079 | CHEMBL5195204 | 2,2-dimethyl-N-[(6-methyl-5-{[2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yl]oxy}pyridin-2-yl)carbamoyl]propanamide | n/a | |
| 12 | P07333_IXH | IXH | n/a | 24851686 | n/a | 8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[(3R,5S)-3,5-dimethylpiperazin-1-yl]phenyl}amino)-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide | n/a | |
| 13 | P07333_KRJ | KRJ | n/a | 11696478 | CHEMBL257154 | 4-cyano-N-(2-cyclohex-1-en-1-yl-4-piperidin-4-ylphenyl)-1H-imidazole-2-carboxamide | n/a | |
| 14 | P07333_KRL | KRL | n/a | 11502871 | CHEMBL398509 | 5-cyano-N-[4-(4-methylpiperazin-1-yl)-2-piperidin-1-ylphenyl]furan-2-carboxamide | n/a | |
| 15 | P07333_LC0 | LC0 | n/a | 46870016 | CHEMBL1087662 | 3-({4-methoxy-5-[(4-methoxybenzyl)oxy]pyridin-2-yl}methoxy)-5-(1-methyl-1H-pyrazol-4-yl)pyrazin-2-amine | n/a | |
| 16 | P07333_LMR | LMR | n/a | 222656;138628585; | CHEMBL1234046 | (2S)-2-hydroxybutanedioic acid | n/a | |
| 17 | P07333_M9T | M9T | n/a | n/a | CHEMBL4555040 | 2-[(4-methoxy-2-methyl-phenyl)amino]-7-methyl-9-(4-oxidanylcyclohexyl)purin-8-one | n/a | |
| 18 | P07333_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 19 | P07333_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 20 | P07333_NAG | NAG | DB00141 | 24139 | CHEMBL447878 | 2-acetamido-2-deoxy-beta-D-glucopyranose | n/a | |
| 21 | P07333_P31 | P31 | DB12978 | 25151352 | CHEMBL3813873 | 5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-{[6-(trifluoromethyl)pyridin-3-yl]methyl}pyridin-2-amine | inhibitor | |
| 22 | P07333_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 23 | P07333_UF4 | UF4 | n/a | 126484197 | n/a | 4-(3-{[(2S)-2-(6-methoxypyridin-3-yl)-2,3-dihydro-1,4-benzodioxin-6-yl]methyl}-3H-imidazo[4,5-b]pyridin-6-yl)-2-methylbut-3-yn-2-amine | n/a | |
| 24 | P07333_UIK | UIK | n/a | 168069186 | CHEMBL5406924 | [4-[4-[methyl-[(3-methylphenyl)methyl]amino]-7~{H}-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]methanol | n/a | |
| 25 | P07333_Z6V | Z6V | DB17520 | 86267612 | CHEMBL5095202 | Vimseltinib | inhibitor | |
| 26 | P07333_STI | STI | DB00619 | 5291 | CHEMBL941 | 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE | antagonist | IC50(nM) = 291.0 Kd(nM) = 10.0 |
| 27 | P07333_B49 | B49 | DB01268 | 5329102 | CHEMBL535 | Sunitinib | inhibitor | IC50(nM) = 12.0 Kd(nM) = 2.0 |
| 28 | P07333_DB06080 | n/a | DB06080 | n/a | n/a | Linifanib | n/a | |
| 29 | P07333_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor | |
| 30 | P07333_5SF | 5SF | DB12147 | 67462786 | CHEMBL3545376 | Erdafitinib | substrate |