Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
P07477 TRY1_HUMAN
Gene name: PRSS1
Protein name: Serine protease 1

List of molecules and drugs that interact with protein P07477

# DrugDomain Data PBD ligand DrugBank Accession PubChem ChEMBL Name Drug action Affinity data
1 P07477_0G6 0G6 DB06841 131704300;137347858; n/a D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide n/a
2 P07477_CA CA n/a 271 n/a CALCIUM ION n/a
3 P07477_ISP ISP DB03976 15391 CHEMBL144888 PHOSPHORYLISOPROPANE n/a
4 P07477_SO4 SO4 DB14546 1117 n/a SULFATE ION n/a
5 P07477_270 270 DB01665 4469371 n/a 2H-Benzimidazol-2-amine n/a
6 P07477_BAB BAB DB01705 6398417;78408105;131704176; n/a Bis(5-Amidino-Benzimidazolyl)Methane n/a
7 P07477_130 130 DB01725 1504 CHEMBL327715 2-{2-hydroxy-[1,1'-biphenyl]-3-yl}-1H-1,3-benzodiazole-5-carboximidamide n/a
8 P07477_ANH ANH DB01737 131624 n/a Nalpha-(2-Naphthylsulfonylglycyl)-3-Amidino-D,L-Phenylalanine-Isopropylester n/a
9 P07477_693 693 DB01741 135559087 n/a CRA_17693 n/a
10 P07477_FD2 FD2 DB01745 446605 CHEMBL343892 N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)Isopipecolinic Acid Methyl Ester n/a
11 P07477_BAI BAI DB01767 1282 CHEMBL46148 Hemi-Babim n/a
12 P07477_991 991 DB01771 447488 n/a CRA_10991 n/a Ki(nM) = 2300.0
13 P07477_MIS MIS DB01805 n/a n/a Monoisopropylphosphorylserine n/a
14 P07477_ZEN ZEN DB01836 446399 CHEMBL270527 [4-(6-Chloro-Naphthalene-2-Sulfonyl)-Piperazin-1-Yl]-(3,4,5,6-Tetrahydro-2h-[1,4']Bipyridinyl-4-Yl)-Methanone n/a
15 P07477_BAO BAO DB01876 2281 n/a Bis(5-Amidino-2-Benzimidazolyl)Methanone n/a
16 P07477_123 123 DB01905 1502 n/a 2-(2-Hydroxy-5-Methoxy-Phenyl)-1h-Benzoimidazole-5-Carboxamidine n/a
17 P07477_ABI ABI DB01939 1800 n/a 5-Amidino-Benzimidazole n/a
18 P07477_AML AML DB02045 8060 n/a Amylamine n/a
19 P07477_847 847 DB02063 131704187;135559083; n/a CRA_16847 n/a
20 P07477_BBA BBA DB02081 17753851 n/a Bis-Benzamidine n/a
21 P07477_312 312 DB02084 131704188;135559086; n/a CRA_17312 n/a
22 P07477_DB02112 n/a DB02112 n/a n/a Zk-806450 n/a Ki(nM) = 40.0
23 P07477_IMA IMA DB02269 446978 CHEMBL1190476 [4-({[5-Benzyloxy-1-(3-Carbamimidoyl-Benzyl)-1h-Indole-2-Carbonyl]-Amino}-Methyl)-Phenyl]-Trimethyl-Ammonium n/a
24 P07477_122 122 DB02287 1505 n/a 2-(2-hydroxy-phenyl)-3H-benzoimidazole-5-carboxamidine n/a Ki(nM) = 17000.0
25 P07477_334 334 DB02288 447510 CHEMBL95097 CRA-9334 n/a
26 P07477_R11 R11 DB02354 445756 n/a 4-{[1-Methyl-5-(2-Methyl-Benzoimidazol-1-Ylmethyl)-1h-Benzoimidazol-2-Ylmethyl]-Amino}-Benzamidine n/a
27 P07477_762 762 DB02366 447484 n/a CRA_10762 n/a
28 P07477_AMC AMC DB02435 448748 n/a Aminomethylcyclohexane n/a
29 P07477_124 124 DB02463 1507 n/a 2-(2-Hydroxy-Phenyl)-1h-Indole-5-Carboxamidine inhibitor
30 P07477_ABN ABN DB02464 7504 CHEMBL522 Benzylamine n/a Ki(nM) = 2.999162519E8
31 P07477_655 655 DB02526 447480 CHEMBL303992 CRA_10655 n/a
32 P07477_DB02665 n/a DB02665 n/a n/a (1R,2S)-2-Phenylcyclopropanaminium n/a
33 P07477_PR1 PR1 DB02744 445482 CHEMBL330572 RPR131247 n/a Ki(nM) = 1000.0
34 P07477_ABB ABB DB02812 5287596 CHEMBL256892 RWJ-56423 inhibitor
35 P07477_802 802 DB02875 447502 CHEMBL92277 CRA_1802 n/a
36 P07477_972 972 DB02989 447486 CHEMBL62492 CRA_10972 n/a
37 P07477_801 801 DB03016 1513 n/a CRA_1801 n/a
38 P07477_CCR CCR DB03081 177837 CHEMBL1231689 [N-[N-(4-Methoxy-2,3,6-trimethylphenylsulfonyl)-L-aspartyl]-D-(4-amidino-phenylalanyl)]-piperidine n/a
39 P07477_DB03127 n/a DB03127 n/a n/a Benzamidine inhibitor
40 P07477_ESI ESI DB03136 1746 n/a 4-Iodobenzo[B]Thiophene-2-Carboxamidine n/a
41 P07477_696 696 DB03159 447476 CHEMBL96433 CRA_8696 n/a Ki(nM) = 190.0
42 P07477_CR3 CR3 DB03173 447478 CHEMBL64579 CRA_10433 n/a Ki(nM) = 700.0
43 P07477_BAK BAK DB03213 2280;131704234; n/a Bis(5-Amidino-2-Benzimidazolyl)Methane Ketone n/a
44 P07477_FBA FBA DB03243 448749 n/a 4-Fluorobenzylamine n/a
45 P07477_RWJ RWJ DB03251 5289320 CHEMBL164138 RWJ-51084 n/a Ki(nM) = 30.0
46 P07477_GP8 GP8 DB03337 444581 CHEMBL1233097 1-(2-Amidinophenyl)-3-(Phenoxyphenyl)Urea n/a
47 P07477_711 711 DB03373 n/a n/a ZK-806711 n/a
48 P07477_TYI TYI DB03374 9305;7058163; CHEMBL1236469 3,5-Diiodotyrosine n/a
49 P07477_169 169 DB03417 6323182 n/a (2S,3R)-2-[[4-(Tert-butylcarbamoyl)piperazine-1-carbonyl]amino]-6-(diaminomethylideneamino)-3-formylhexanoic acid n/a
50 P07477_DB03443 n/a DB03443 n/a n/a bis(5-amidino-benzimidazolyl)methanone zinc n/a
51 P07477_CR9 CR9 DB03555 447490 CHEMBL62807 CRA_11092 n/a
52 P07477_785 785 DB03595 447514 n/a CRA_9785 n/a
53 P07477_BRN BRN DB03608 2354 CHEMBL35241 Diminazene n/a
54 P07477_CR4 CR4 DB03643 1506 CHEMBL433501 CRA_1144 n/a
55 P07477_132 132 DB03865 445843 n/a 6-Chloro-2-(2-Hydroxy-Biphenyl-3-Yl)-1h-Indole-5-Carboxamidine n/a Ki(nM) = 770.0
56 P07477_ESP ESP DB03876 5438 n/a Thieno[2,3-B]Pyridine-2-Carboxamidine n/a
57 P07477_DB04008 n/a DB04008 n/a n/a Zinc;[amino-[2-[[5-[amino(azaniumylidene)methyl]benzimidazol-1-id-2-yl]methyl]benzimidazol-1-id-5-yl]methylidene]azanium n/a
58 P07477_T87 T87 DB04107 9600423 n/a [(1-{2[(4-Carbamimidoyl-Phenylamino)-Methyl]-1-Methyl-1h-Benzoimidazol-5-Yl}-Cyclopropyl)-Pyridin-2-Yl-Methyleneaminooxy]-Acetic Acid Ethyl Ester n/a
59 P07477_FD4 FD4 DB04125 178051 CHEMBL104815 N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)-4-Acetyl-Piperazine n/a
60 P07477_907 907 DB04215 447508 CHEMBL48608 CRA_9076 n/a Ki(nM) = 460.0
61 P07477_FD1 FD1 DB04238 446604 CHEMBL1161253 N-Alpha-(2-Naphthylsulfonyl)-N-(3-Amidino-L-Phenylalaninyl)-D-Pipecolinic Acid n/a
62 P07477_653 653 DB04246 135559095 n/a CRA_23653 n/a
63 P07477_CTA CTA DB04269 5287991 CHEMBL342672 Cyclotheonamide A n/a
64 P07477_BAH BAH DB04301 2384;131704276;135678108; n/a Bis(5-Amidino-2-Benzimidazolyl)Methane Ketone Hydrate n/a
65 P07477_PBN PBN DB04311 83242 CHEMBL79512 4-Phenylbutylamine n/a Ki(nM) = 20000.0
Kd(nM) = 1.9952623E7
66 P07477_DB04325 n/a DB04325 n/a n/a Phenethylamine n/a
67 P07477_GP6 GP6 DB04336 2014 n/a 1-(4-Amidinophenyl)-3-(4-Chlorophenyl)Urea n/a
68 P07477_DB04391 n/a DB04391 n/a n/a Aeruginosin 98-B n/a
69 P07477_PRA PRA DB04410 16259 CHEMBL276864 3-Phenylpropylamine n/a
70 P07477_RPR RPR DB04424 5497056 CHEMBL48046 RPR128515 n/a Ki(nM) = 69.0
71 P07477_623 623 DB04432 4470378 n/a ZK-805623 n/a
72 P07477_120 120 DB04442 1509;5287420; n/a Imino[2-(2-oxo-1,2-dihydro-3-pyridinyl)-1H-benzimidazol-5-yl]methanaminium n/a
73 P07477_ESX ESX DB04446 444753 n/a Benzo[B]Thiophene-2-Carboxamidine n/a
74 P07477_656 656 DB04470 447482 CHEMBL64676 CRA_10656 n/a
75 P07477_678 678 DB04563 17753799 n/a CRA_9678 n/a
76 P07477_C1R C1R DB04654 11840929 n/a 4-PIPERIDIN-4-YLBUTANAL n/a
77 P07477_TL1 TL1 DB04790 5326924 n/a 2,5-bis-O-{3-[amino(imino)methyl]phenyl}-1,4:3,6-dianhydro-D-glucitol n/a
78 P07477_TL2 TL2 DB04791 5326925 n/a 2-O-(4'-AMIDINOPHENYL)-5-O-(3''-AMIDINOPHENYL)-1,4:3,6-DIANHYDRO-D-SORBITOL n/a
79 P07477_TL3 TL3 DB04792 5326926 n/a 2,5-O,O-BIS-{4',4''-AMIDINOPHENYL}-1,4:3,6-DIANHYDRO-D-SORBITOL n/a
80 P07477_TL4 TL4 DB04793 5326927 n/a 1,4:3,6-Dianhydro-2-O-(3-carbamimidoylphenyl)-5-O-(4-carbamimidoylphenyl)-D-glucitol n/a
81 P07477_DB06840 n/a DB06840 n/a n/a diethyl [(1R)-1,5-diaminopentyl]boronate n/a
82 P07477_10U 10U DB06845 23629654 n/a (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentylamino)ethanoyl)pyrrolidine-2-carboxamide n/a
83 P07477_11U 11U DB06850 44141860 n/a (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclohexylamino)ethanoyl)pyrrolidine-2-carboxamide n/a
84 P07477_12U 12U DB06853 25113614 n/a N-cycloheptylglycyl-N-(4-carbamimidoylbenzyl)-L-prolinamide n/a
85 P07477_950 950 DB06855 445847 CHEMBL62836 6-fluoro-2-(2-hydroxy-3-isobutoxy-phenyl)-1H-benzoimidazole-5-carboxamidine n/a
86 P07477_13U 13U DB06858 46937030 n/a N-cyclooctylglycyl-N-(4-carbamimidoylbenzyl)-L-prolinamide n/a
87 P07477_22M 22M DB06918 9547940 n/a 2-(2-METHYLPHENYL)-1H-INDOLE-6-CARBOXIMIDAMIDE n/a
88 P07477_23M 23M DB06923 9547939 n/a 2-(3-METHYLPHENYL)-1H-INDOLE-5-CARBOXIMIDAMIDE n/a
89 P07477_45U 45U DB07088 24963035 n/a (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentyloxy)ethanoyl)pyrrolidine-2-carboxamide n/a
90 P07477_46U 46U DB07091 24963036 n/a (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclohexyloxy)ethanoyl)pyrrolidine-2-carboxamide n/a
91 P07477_49U 49U DB07095 24963037 CHEMBL1198650 (S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclopentylpropanoyl)pyrrolidine-2-carboxamide n/a
92 P07477_50U 50U DB07131 25134248 CHEMBL1198138 (S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclohexylpropanoyl)pyrrolidine-2-carboxamide n/a
93 P07477_783 783 DB07229 447492 n/a 3-{5-[AMINO(IMINIO)METHYL]-1H-INDOL-2-YL}-5-METHOXY-1,1'-BIPHENYL-2-OLATE n/a Ki(nM) = 130.0
94 P07477_AM4 AM4 DB07368 199994 CHEMBL186483 4-(METHYLSULFONYL)BENZENECARBOXIMIDAMIDE n/a
95 P07477_BRV BRV DB07491 18432427 n/a 5-amino-2,4,6-tribromobenzene-1,3-dicarboxylic acid n/a
96 P07477_IN4 IN4 DB07985 444406 n/a +/-METHYL 4-(AMINOIMINOMETHYL)-BETA-[3- INH (AMINOIMINO)PHENYL]BENZENE PENTANOATE n/a
97 P07477_MI2 MI2 DB08184 9547945 n/a 2-(2-METHYLPHENYL)-1H-INDOLE-5-CARBOXIMIDAMIDE n/a
98 P07477_DB08254 n/a DB08254 n/a n/a 2-Naphthalenesulfonic acid n/a
99 P07477_PPB PPB DB08420 5289192 n/a 1-{[1-(2-AMINO-3-PHENYL-PROPIONYL)-PYRROLIDINE-2-CARBONYL]-AMINO}-2-(3-CYANO-PHENYL)-ETHANEBORONIC ACID n/a
100 P07477_ZAP ZAP DB08763 447110 n/a [N-(BENZYLOXYCARBONYL)AMINO](4-AMIDINOPHENYL)METHANE-PHOSPHONATE n/a
101 P07477_7RF 7RF DB12598 4413 CHEMBL273264 Nafamostat inhibitor
102 P07477_DB13729 n/a DB13729 n/a n/a Camostat inhibitor