Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
P07550 ADRB2_HUMAN
Gene name: ADRB2
Protein name: Beta-2 adrenergic receptor

List of molecules and drugs that interact with protein P07550

# DrugDomain Data PBD ligand DrugBank Accession PubChem ChEMBL Name Drug action Affinity data
1 P07550_CLR CLR DB04540 5997 CHEMBL112570 CHOLESTEROL n/a
2 P07550_DZQ DZQ DB09080 11504295 CHEMBL605846 Olodaterol agonist
3 P07550_ERC ERC n/a 49835963 n/a 8-hydroxy-5-[(1R)-1-hydroxy-2-({2-[3-methoxy-4-(3-sulfanylpropoxy)phenyl]ethyl}amino)ethyl]quinolin-2(1H)-one n/a
4 P07550_H98 H98 DB01274 3083544 CHEMBL1363 ~{N}-[5-[(1~{R})-2-[[(2~{R})-1-(4-methoxyphenyl)propan-2-yl]amino]-1-oxidanyl-ethyl]-2-oxidanyl-phenyl]methanamide agonist Ki(nM) = 23.0
EC50(nM) = 0.19
5 P07550_JRZ JRZ n/a 5311179 CHEMBL1233766 (2S,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]butan-2-ol n/a
6 P07550_JSZ JSZ n/a 913103 CHEMBL1233771 ethyl 4-({(2S)-2-hydroxy-3-[(1-methylethyl)amino]propyl}oxy)-3-methyl-1-benzofuran-2-carboxylate n/a
7 P07550_JTZ JTZ n/a 204665 CHEMBL1160734 (2S)-1-[(1-methylethyl)amino]-3-(2-prop-2-en-1-ylphenoxy)propan-2-ol n/a
8 P07550_OLA OLA n/a 445639 CHEMBL8659 OLEIC ACID n/a
9 P07550_OLC OLC n/a 11451146 n/a (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate n/a
10 P07550_P0G P0G n/a 49837874 CHEMBL1615159 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one n/a
11 P07550_PGE PGE DB02327 8172 CHEMBL1235259 TRIETHYLENE GLYCOL n/a
12 P07550_SO4 SO4 DB14546 1117 n/a SULFATE ION n/a
13 P07550_TIM TIM DB00373 33624 CHEMBL499 (2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol antagonist Kd(nM) = 0.21
14 P07550_SPM SPM DB00127 1103 CHEMBL23194 Spermine n/a
15 P07550_DB00195 n/a DB00195 n/a n/a Betaxolol antagonist
16 P07550_DB00221 n/a DB00221 n/a n/a Isoetharine agonist Kd(nM) = 1000.0
17 P07550_DB00248 n/a DB00248 n/a n/a Cabergoline binder
18 P07550_DB00264 n/a DB00264 n/a n/a Metoprolol antagonist Ki(nM) = 220.0
Kd(nM) = 129.0
19 P07550_DB00335 n/a DB00335 n/a n/a Atenolol antagonist Ki(nM) = 8140.0
Kd(nM) = 260.0
20 P07550_LNR LNR DB00368 439260 CHEMBL1437 Norepinephrine agonist Ki(nM) = 3300.0
Kd(nM) = 3980.0
21 P07550_DB00397 n/a DB00397 n/a n/a Phenylpropanolamine agonist
22 P07550_DB00449 n/a DB00449 n/a n/a Dipivefrin agonist
23 P07550_DB00489 n/a DB00489 n/a n/a Sotalol antagonist Ki(nM) = 1900.0
Kd(nM) = 141.0
24 P07550_DB00521 n/a DB00521 n/a n/a Carteolol antagonist
25 P07550_DB00571 n/a DB00571 n/a n/a Propranolol antagonist Ki(nM) = 0.01
IC50(nM) = 0.48
Kd(nM) = 0.1
26 P07550_DB00598 n/a DB00598 n/a n/a Labetalol antagonist Kd(nM) = 9.3
27 P07550_DB00612 n/a DB00612 n/a n/a Bisoprolol antagonist Ki(nM) = 250.0
Kd(nM) = 150.0
28 P07550_ALE ALE DB00668 5816;139148732; CHEMBL679 Epinephrine agonist Ki(nM) = 360.0
Kd(nM) = 630.0
EC50(nM) = 1380.0
29 P07550_DB00816 n/a DB00816 n/a n/a Orciprenaline agonist Kd(nM) = 501.0
30 P07550_DB00841 n/a DB00841 n/a n/a Dobutamine agonist
31 P07550_DB00852 n/a DB00852 n/a n/a Pseudoephedrine partial agonist
32 P07550_DB00866 n/a DB00866 n/a n/a Alprenolol antagonist Ki(nM) = 1.2
IC50(nM) = 1.1
Kd(nM) = 0.295121
33 P07550_DB00867 n/a DB00867 n/a n/a Ritodrine agonist
34 P07550_DB00871 n/a DB00871 n/a n/a Terbutaline agonist Ki(nM) = 2511.89
Kd(nM) = 3.2
EC50(nM) = 3162.0
35 P07550_DB00901 n/a DB00901 n/a n/a Bitolterol n/a
36 P07550_DB00925 n/a DB00925 n/a n/a Phenoxybenzamine n/a Ki(nM) = 10000.0
37 P07550_DB00938 n/a DB00938 n/a n/a Salmeterol agonist Ki(nM) = 0.18
IC50(nM) = 5.0
Kd(nM) = 0.3
EC50(nM) = 0.044668
38 P07550_DB00960 n/a DB00960 n/a n/a Pindolol partial agonist Ki(nM) = 0.32
Kd(nM) = 0.537032
39 P07550_DB00983 n/a DB00983 n/a n/a Formoterol agonist Ki(nM) = 2.6
Kd(nM) = 2.5
EC50(nM) = 0.199526
40 P07550_DB01001 n/a DB01001 n/a n/a Salbutamol agonist Ki(nM) = 501.19
IC50(nM) = 980.0
Kd(nM) = 1.0
EC50(nM) = 0.11
41 P07550_DB01064 n/a DB01064 n/a n/a Isoprenaline agonist Ki(nM) = 2.4
Kd(nM) = 50.0
EC50(nM) = 0.054954
42 P07550_DB01102 n/a DB01102 n/a n/a Arbutamine agonist
43 P07550_DB01136 n/a DB01136 n/a n/a Carvedilol antagonist Ki(nM) = 0.19
Kd(nM) = 0.194984
44 P07550_DSM DSM DB01151 2995 CHEMBL72 Desipramine antagonist
45 P07550_DB01182 n/a DB01182 n/a n/a Propafenone antagonist
46 P07550_DB01193 n/a DB01193 n/a n/a Acebutolol partial agonist Kd(nM) = 832.0
47 P07550_DB01203 n/a DB01203 n/a n/a Nadolol antagonist Kd(nM) = 2.5
48 P07550_DB01210 n/a DB01210 n/a n/a Levobunolol antagonist
49 P07550_DB01214 n/a DB01214 n/a n/a Metipranolol antagonist
50 P07550_9SC 9SC DB01238 60795 CHEMBL1112 Aripiprazole ligand Ki(nM) = 163.0
51 P07550_DB01288 n/a DB01288 n/a n/a Fenoterol agonist Ki(nM) = 719.0
Kd(nM) = 100.0
52 P07550_DB01291 n/a DB01291 n/a n/a Pirbuterol agonist
53 P07550_DB01295 n/a DB01295 n/a n/a Bevantolol antagonist
54 P07550_DB01359 n/a DB01359 n/a n/a Penbutolol antagonist
55 P07550_DB01364 n/a DB01364 n/a n/a Ephedrine agonist
56 P07550_DB01366 n/a DB01366 n/a n/a Procaterol agonist Ki(nM) = 33.0
57 P07550_DB01407 n/a DB01407 n/a n/a Clenbuterol agonist Ki(nM) = 570.0
IC50(nM) = 1300.0
Kd(nM) = 16.0
EC50(nM) = 6.2
58 P07550_DB01408 n/a DB01408 n/a n/a Bambuterol agonist
59 P07550_DB01580 n/a DB01580 n/a n/a Oxprenolol antagonist
60 P07550_PUT PUT DB01917 1045 CHEMBL46257 Putrescine n/a
61 P07550_SPD SPD DB03566 1102 CHEMBL19612 Spermidine n/a
62 P07550_DB04846 n/a DB04846 n/a n/a Celiprolol agonist
63 P07550_DB04861 n/a DB04861 n/a n/a Nebivolol antagonist
64 P07550_DB05039 n/a DB05039 n/a n/a Indacaterol agonist Ki(nM) = 16.0
EC50(nM) = 0.79
65 P07550_DB05590 n/a DB05590 n/a n/a Bedoradrine agonist
66 P07550_DB06216 n/a DB06216 n/a n/a Asenapine antagonist Ki(nM) = 5000.0
67 P07550_DB06262 n/a DB06262 n/a n/a Droxidopa agonist
68 P07550_DB06814 n/a DB06814 n/a n/a Protokylol agonist
69 P07550_CAU CAU DB07543 13023332 n/a (S)-carazolol n/a
70 P07550_DB08807 n/a DB08807 n/a n/a Bopindolol antagonist
71 P07550_DB08808 n/a DB08808 n/a n/a Bupranolol antagonist Kd(nM) = 0.14
72 P07550_DB09013 n/a DB09013 n/a n/a Befunolol n/a
73 P07550_DB09080 n/a DB09080 n/a n/a Olodaterol agonist
74 P07550_DB09082 n/a DB09082 n/a n/a Vilanterol agonist
75 P07550_DB09185 n/a DB09185 n/a n/a Viloxazine antagonist
76 P07550_DB09204 n/a DB09204 n/a n/a Arotinolol antagonist
77 P07550_DB09273 n/a DB09273 n/a n/a Doxofylline agonist
78 P07550_DB11587 n/a DB11587 n/a n/a Etafedrine agonist
79 P07550_DB12248 n/a DB12248 n/a n/a Tulobuterol regulator
80 P07550_68H 68H DB13139 123600 CHEMBL1002 Levosalbutamol agonist
81 P07550_DB13624 n/a DB13624 n/a n/a Methoxyphenamine regulator