Gene name: CTSL
Protein name: Procathepsin L (EC
List of molecules and drugs that interact with protein P07711
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P07711_1PE | 1PE | n/a | 62551 | CHEMBL1229766 | PENTAETHYLENE GLYCOL | n/a | |
| 2 | P07711_424 | 424 | n/a | n/a | n/a | (2S,4R)-1-[1-(4-chlorophenyl)cyclopropyl]carbonyl-4-(2-chlorophenyl)sulfonyl-N-[1-(iminomethyl)cyclopropyl]pyrrolidine-2-carboxamide | n/a | |
| 3 | P07711_5T9 | 5T9 | n/a | n/a | n/a | (2~{S},4~{R})-4-[(2-chloranyl-4-methoxy-phenyl)-bis(oxidanyl)-$l^{4}-sulfanyl]-1-[3-(5-chloranylpyridin-2-yl)azetidin-3-yl]carbonyl-~{N}-[1-(iminomethyl)cyclopropyl]pyrrolidine-2-carboxamide | n/a | |
| 4 | P07711_7KH | 7KH | n/a | n/a | n/a | ~{N}-cyclopentyl-~{N}-(imidazo[1,2-a]pyridin-2-ylmethyl)-4-(iminomethyl)-6-morpholin-4-yl-1,3,5-triazin-2-amine | n/a | |
| 5 | P07711_7KN | 7KN | n/a | 137348634 | n/a | [4-[cyclopentyl(pyrazin-2-ylmethyl)amino]-6-morpholin-4-yl-1,3,5-triazin-2-yl]methylideneazanide | n/a | |
| 6 | P07711_89B | 89B | n/a | 168451633 | n/a | N-[(2S)-3-(4-fluorophenyl)-1-oxidanylidene-1-[[(2R,3S)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-1-benzofuran-2-carboxamide | n/a | |
| 7 | P07711_89K | 89K | n/a | 168451634 | n/a | N-[(2S)-3-cyclohexyl-1-oxidanylidene-1-[[(2S,3S)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-1-benzofuran-2-carboxamide | n/a | |
| 8 | P07711_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 9 | P07711_ALD | ALD | n/a | 5287667 | n/a | N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S)-1-hydroxy-4-methylpentan-2-yl]-L-leucinamide | n/a | |
| 10 | P07711_BD3 | BD3 | n/a | n/a | n/a | Nalpha-[(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)carbonyl]-N-[(2E)-2-iminoethyl]-3-{5-[(Z)-iminomethyl]-1,3,4-oxadiazol-2-yl}-L-phenylalaninamide | n/a | |
| 11 | P07711_BTB | BTB | n/a | 81462 | n/a | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | n/a | |
| 12 | P07711_C3E | C3E | n/a | 71656261 | CHEMBL4110750 | (3~{S},14~{E})-19-chloranyl-~{N}-(1-cyanocyclopropyl)-5-oxidanylidene-12,17-dioxa-4-azatricyclo[16.2.2.0^{6,11}]docosa-1(21),6(11),7,9,14,18(22),19-heptaene-3-carboxamide | n/a | |
| 13 | P07711_C7Q | C7Q | n/a | n/a | n/a | (3~{S},14~{E})-19-chloranyl-~{N}-[1-(iminomethyl)cyclopropyl]-5-oxidanylidene-17-oxa-4-azatricyclo[16.2.2.0^{6,11}]docosa-1(21),6,8,10,14,18(22),19-heptaene-3-carboxamide | n/a | |
| 14 | P07711_C7T | C7T | n/a | 71656941 | CHEMBL4107237 | (3~{S},14~{E})-8-(azetidin-3-yl)-19-chloranyl-~{N}-(1-cyanocyclopropyl)-5-oxidanylidene-12,17-dioxa-4-azatricyclo[16.2.2.0^{6,11}]docosa-1(21),6(11),7,9,14,18(22),19-heptaene-3-carboxamide | n/a | |
| 15 | P07711_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 16 | P07711_D1R | D1R | n/a | 52946595 | n/a | NALPHA-[(4-METHYLPIPERAZIN-1-YL)CARBONYL]-N-{(1S)-3-PHENYL-1-[2-(PHENYLSULFONYL)ETHYL]PROPYL}-L-PHENYLALANINAMIDE | n/a | |
| 17 | P07711_DJT | DJT | n/a | n/a | n/a | (2S,4R)-4-(2-chlorophenyl)sulfonyl-1-[1-(4-fluorophenyl)cyclopropyl]carbonyl-N-[1-(iminomethyl)cyclopropyl]pyrrolidine-2-carboxamide | n/a | |
| 18 | P07711_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 19 | P07711_E64 | E64 | DB04276 | 5288145 | n/a | N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE | n/a | |
| 20 | P07711_E6D | E6D | n/a | 137349231 | n/a | ethyl (3S)-3-hydroxy-4-({(2S)-4-methyl-1-[(3-methylbutyl)amino]-1-oxopentan-2-yl}amino)-4-oxobutanoate | n/a | |
| 21 | P07711_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 22 | P07711_EOH | EOH | DB00898 | 702 | CHEMBL545 | ETHANOL | n/a | |
| 23 | P07711_FLC | FLC | n/a | 31348 | n/a | CITRATE ANION | n/a | |
| 24 | P07711_GH4 | GH4 | n/a | n/a | n/a | 4-[1,3-benzodioxol-5-ylmethyl(2-phenoxyethyl)amino]-5-fluoropyrimidine-2-carbonitrile | n/a | |
| 25 | P07711_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 26 | P07711_I0X | I0X | n/a | 101235863 | n/a | Nalpha-[(benzyloxy)carbonyl]-N-[(1S)-1-(4-tert-butoxybenzyl)-3-diazo-2-oxopropyl]-L-phenylalaninamide | n/a | |
| 27 | P07711_I0Y | I0Y | n/a | 72200290 | n/a | Nalpha-[(benzyloxy)carbonyl]-N-[(2S)-1-(4-tert-butoxyphenyl)-4-hydroxy-3-oxobutan-2-yl]-L-phenylalaninamide | n/a | |
| 28 | P07711_JQO | JQO | n/a | 11728473 | n/a | (2S)-2-[(4-fluorophenyl)sulfonylamino]-3-methyl-N-[(2S)-4-methyl-1-oxidanyl-pentan-2-yl]butanamide | n/a | |
| 29 | P07711_KH0 | KH0 | n/a | 168475478 | n/a | ~{tert}-butyl ~{N}-[1-[(2~{S})-3-cyclopropyl-1-oxidanylidene-1-[[(2~{S},3~{S})-3-oxidanyl-4-oxidanylidene-1-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-2-oxidanylidene-pyridin-3-yl]carbamate | n/a | |
| 30 | P07711_KJ0 | KJ0 | n/a | 168654845 | n/a | N-[(2S)-3-cyclohexyl-1-[[(2S,3S)-4-(cyclopropylamino)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]butan-2-yl]amino]-1-oxidanylidene-propan-2-yl]-1-benzofuran-2-carboxamide | n/a | |
| 31 | P07711_L2F | L2F | n/a | 11799355 | n/a | N-(1-naphthylsulfonyl)-(L)-isoleucyl-(L)-tryptophanol | n/a | |
| 32 | P07711_L2X | L2X | n/a | 50909779 | n/a | (2S,3S)-N3-[2-(4-hydroxyphenyl)ethyl]-N2-[(2S)-1-oxidanylidene-3-phenyl-1-[(phenylmethyl)amino]propan-2-yl]oxirane-2,3-dicarboxamide | n/a | |
| 33 | P07711_L3F | L3F | n/a | 9843057 | n/a | (phenylmethyl) N-[(2S)-3-methyl-1-oxidanylidene-1-[[(2S)-1-oxidanyl-3-phenyl-propan-2-yl]amino]butan-2-yl]carbamate | n/a | |
| 34 | P07711_M6L | M6L | n/a | 168451661 | n/a | (phenylmethyl) ~{N}-[(2~{S})-4-methyl-1-oxidanylidene-1-[[(2~{S},3~{S})-2-oxidanyl-1-oxidanylidene-1-(pyridin-2-ylmethylamino)hexan-3-yl]amino]pentan-2-yl]carbamate | n/a | |
| 35 | P07711_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 36 | P07711_NAG | NAG | DB00141 | 24139 | CHEMBL447878 | 2-acetamido-2-deoxy-beta-D-glucopyranose | n/a | |
| 37 | P07711_NOW | NOW | n/a | n/a | n/a | Nalpha-[(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)carbonyl]-N-[(2Z)-2-iminoethyl]-3-methyl-L-phenylalaninamide | n/a | |
| 38 | P07711_NSX | NSX | n/a | 9988478 | n/a | N~2~,N~6~-bis(biphenyl-4-ylacetyl)-L-lysyl-D-arginyl-N-(2-phenylethyl)-L-tyrosinamide | n/a | |
| 39 | P07711_NSY | NSY | n/a | 9988448 | n/a | N~2~,N~6~-bis(biphenyl-4-ylacetyl)-L-lysyl-D-arginyl-N-(2-phenylethyl)-L-phenylalaninamide | n/a | |
| 40 | P07711_NSZ | NSZ | n/a | 9918384 | n/a | N-(biphenyl-4-ylacetyl)-S-methyl-L-cysteinyl-D-arginyl-N-(2-phenylethyl)-L-phenylalaninamide | n/a | |
| 41 | P07711_OPT | OPT | n/a | 49867445 | n/a | S-benzyl-N-(biphenyl-4-ylacetyl)-L-cysteinyl-N~5~-(diaminomethyl)-D-ornithyl-N-(2-phenylethyl)-L-tyrosinamide | n/a | |
| 42 | P07711_OYU | OYU | n/a | 2733206 | n/a | ~{tert}-butyl ~{N}-(2-hydroxyethyl)carbamate | n/a | |
| 43 | P07711_P6G | P6G | n/a | 17472 | CHEMBL1235082 | HEXAETHYLENE GLYCOL | n/a | |
| 44 | P07711_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 45 | P07711_PG4 | PG4 | n/a | 8200 | CHEMBL1235254 | TETRAETHYLENE GLYCOL | n/a | |
| 46 | P07711_PGE | PGE | DB02327 | 8172 | CHEMBL1235259 | TRIETHYLENE GLYCOL | n/a | |
| 47 | P07711_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 48 | P07711_POL | POL | DB03175 | 1031 | CHEMBL14687 | N-PROPANOL | n/a | |
| 49 | P07711_RN2 | RN2 | n/a | 15168139 | n/a | Calpeptin | n/a | |
| 50 | P07711_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 51 | P07711_TXH | TXH | n/a | 166513905 | n/a | ~{tert}-butyl ~{N}-[(2~{S})-3-(1~{H}-indol-3-yl)-1-(2-methanoylhydrazinyl)-1-oxidanylidene-propan-2-yl]carbamate | n/a | |
| 52 | P07711_UED | UED | n/a | 78225172 | n/a | N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide | n/a | |
| 53 | P07711_V65 | V65 | n/a | 137350112 | n/a | 4-[(4-chlorobenzyl)(cyclohexyl)amino]-6-morpholin-4-yl-1,3,5-triazine-2-carboxamide | n/a | |
| 54 | P07711_WRH | WRH | n/a | 168475499 | n/a | methyl (2S)-1-[(2S,3S)-3-methyl-2-[[(3S)-3-oxidanyl-4-oxidanylidene-4-(propylamino)butanoyl]amino]pentanoyl]pyrrolidine-2-carboxylate | n/a | |
| 55 | P07711_XU3 | XU3 | n/a | n/a | n/a | (2S,4R)-4-(2-chlorophenyl)sulfonyl-1-[1-(5-chlorothiophen-2-yl)cyclopropyl]carbonyl-N-[1-(iminomethyl)cyclopropyl]pyrrolidine-2-carboxamide | n/a | |
| 56 | P07711_XU5 | XU5 | n/a | n/a | n/a | (2S,4R)-4-(2-chlorophenyl)sulfonyl-N-[1-(iminomethyl)cyclopropyl]-1-[1-(4-methylphenyl)cyclopropyl]carbonyl-pyrrolidine-2-carboxamide | n/a | |
| 57 | P07711_YJ2 | YJ2 | n/a | n/a | n/a | (2S,4R)-1-[1-(4-BROMOPHENYL)CYCLOPROPYL]CARBONYL-4-(2-CHLOROPHENYL)SULFONYL-N-[1-(IMINOMETHYL)CYCLOPROPYL]PYRROLIDINE-2-CARBOXAMIDE | n/a | |
| 58 | P07711_YJ8 | YJ8 | n/a | n/a | n/a | (2S,4R)-4-(2-chlorophenyl)sulfonyl-N-[1-(iminomethyl)cyclopropyl]-1-[1-(4-iodophenyl)cyclopropyl]carbonyl-pyrrolidine-2-carboxamide | n/a | |
| 59 | P07711_YJ9 | YJ9 | n/a | n/a | n/a | (2S,4R)-4-(2-chlorophenyl)sulfonyl-N-[1-(iminomethyl)cyclopropyl]-1-[1-[4-(trifluoromethyl)phenyl]cyclopropyl]carbonyl-pyrrolidine-2-carboxamide | n/a | |
| 60 | P07711_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 61 | P07711_OCS | OCS | DB03661 | 72886 | n/a | L-cysteic acid | inhibitor | |
| 62 | P07711_BP4 | BP4 | DB07477 | 3332 | CHEMBL413965 | Felbinac | n/a | |
| 63 | P07711_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor |