Gene name: LYN
Protein name: Tyrosine-protein kinase Lyn
List of molecules and drugs that interact with protein P07948
# | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
---|---|---|---|---|---|---|---|---|
1 | P07948_8H0 | 8H0 | n/a | 78210204 | n/a | N-(1H-indazol-6-yl)-8-piperidin-4-yloxy-6-propyl-quinazolin-2-amine | n/a | |
2 | P07948_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
3 | P07948_FLC | FLC | n/a | 31348 | n/a | CITRATE ANION | n/a | |
4 | P07948_STU | STU | DB02010 | 44259 | CHEMBL388978 | STAUROSPORINE | n/a | |
5 | P07948_1N1 | 1N1 | DB01254 | 3062316 | CHEMBL1421 | Dasatinib | inhibitor | IC50(nM) = 1.2 Kd(nM) = 0.57 |
6 | P07948_PP2 | PP2 | DB03023 | n/a | n/a | 1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine | n/a | |
7 | P07948_DB8 | DB8 | DB06616 | 5328940 | CHEMBL288441 | Bosutinib | inhibitor | IC50(nM) = 8.0 Kd(nM) = 4.2 |
8 | P07948_0LI | 0LI | DB08901 | 24826799 | CHEMBL1171837 | Ponatinib | inhibitor | IC50(nM) = 0.16 |
9 | P07948_XIN | XIN | DB09079 | 9809715 | CHEMBL502835 | Nintedanib | inhibitor | |
10 | P07948_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor |