Gene name: HSP90AB1
Protein name: Heat shock protein
List of molecules and drugs that interact with protein P08238
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P08238_42C | 42C | n/a | 3134 | CHEMBL407391 | N,N-dimethyl-7H-purin-6-amine | n/a | |
| 2 | P08238_7PP | 7PP | n/a | 11517212 | CHEMBL1230584 | 5-{2-amino-4-chloro-7-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-2-methylpent-4-yn-2 -ol | n/a | |
| 3 | P08238_83S | 83S | n/a | 131955110 | n/a | 5-Hydroxy-4-(isoindoline-2-carbonyl)-2-isopropylbenzaldehyde | n/a | |
| 4 | P08238_871 | 871 | n/a | 131955111 | n/a | 2-(5-Hydroxy-4-(isoindoline-2-carbonyl)-2-isopropylphenyl)acetonitrile | n/a | |
| 5 | P08238_874 | 874 | n/a | 135223398 | n/a | (2,4-Dihydroxy-3-(hydroxymethyl)-5-isopropylphenyl)(isoindolin-2-yl)methanone | n/a | |
| 6 | P08238_ADP | ADP | DB16833 | 6022 | CHEMBL14830 | ADENOSINE-5'-DIPHOSPHATE | n/a | |
| 7 | P08238_ANP | ANP | n/a | 33113 | CHEMBL1230989 | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | n/a | |
| 8 | P08238_ATP | ATP | DB00171 | 5957 | CHEMBL14249 | ADENOSINE-5'-TRIPHOSPHATE | n/a | |
| 9 | P08238_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 10 | P08238_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 11 | P08238_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 12 | P08238_K | K | n/a | 813 | CHEMBL1233793 | POTASSIUM ION | n/a | |
| 13 | P08238_KFY | KFY | n/a | 44376524 | CHEMBL350813 | 9-[(2E)-but-2-en-1-yl]-8-[(3,4,5-trimethoxyphenyl)methyl]-9H-purin-6-amine | n/a | |
| 14 | P08238_KU3 | KU3 | n/a | 135567312 | n/a | (5-fluoroisoindolin-2-yl)(4-hydroxy-5-isopropylbenzo[d]isoxazol-7-yl)methanone | n/a | |
| 15 | P08238_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 16 | P08238_MOO | MOO | DB15878 | 24621 | n/a | MOLYBDATE ION | n/a | |
| 17 | P08238_MPD | MPD | DB03564 | 5288834 | n/a | (4S)-2-METHYL-2,4-PENTANEDIOL | n/a | |
| 18 | P08238_PU3 | PU3 | DB02754 | 448965 | CHEMBL113690 | 9-BUTYL-8-(3,4,5-TRIMETHOXYBENZYL)-9H-PURIN-6-AMINE | n/a | IC50(nM) = 1000.0 EC50(nM) = 3200.0 |
| 19 | P08238_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 20 | P08238_GDM | GDM | DB02424 | 5288382 | CHEMBL278315 | Geldanamycin | n/a | |
| 21 | P08238_RDC | RDC | DB03758 | 6323491 | CHEMBL414883 | Radicicol | n/a | |
| 22 | P08238_DB05134 | n/a | DB05134 | n/a | n/a | Tanespimycin | n/a | |
| 23 | P08238_DB06070 | n/a | DB06070 | n/a | n/a | SNX-5422 | inhibitor | |
| 24 | P08238_CT5 | CT5 | DB07594 | 984170 | CHEMBL399530 | CCT-018159 | n/a | |
| 25 | P08238_H64 | H64 | DB07877 | 6914564 | CHEMBL383189 | 8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE | n/a | IC50(nM) = 205.0 EC50(nM) = 38.8 |
| 26 | P08238_KJ2 | KJ2 | DB08045 | 5288672 | n/a | 4-{4-[4-(3-AMINOPROPOXY)PHENYL]-1H-PYRAZOL-5-YL}-6-CHLOROBENZENE-1,3-DIOL | n/a | |
| 27 | P08238_M1S | M1S | DB08153 | 11987878 | n/a | (5E)-14-CHLORO-15,17-DIHYDROXY-4,7,8,9,10,11-HEXAHYDRO-2-BENZOXACYCLOPENTADECINE-1,12(3H,13H)-DIONE | n/a | |
| 28 | P08238_NP4 | NP4 | DB08292 | 11963551 | n/a | (5Z)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE | n/a | |
| 29 | P08238_NP5 | NP5 | DB08293 | 11963552 | n/a | (5E)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE | n/a | |
| 30 | P08238_P2N | P2N | DB08346 | 24916788 | CHEMBL1235084 | (5Z)-13-CHLORO-14,16-DIHYDROXY-3,4,7,8,9,10-HEXAHYDRO-1H-2-BENZOXACYCLOTETRADECINE-1,11(12H)-DIONE | n/a | |
| 31 | P08238_RDA | RDA | DB08464 | 11373270 | n/a | METHYL 3-CHLORO-2-{3-[(2,5-DIHYDROXY-4-METHOXYPHENYL)AMINO]-3-OXOPROPYL}-4,6-DIHYDROXYBENZOATE | n/a | |
| 32 | P08238_RDE | RDE | DB08465 | 11840979 | n/a | 2-(3-AMINO-2,5,6-TRIMETHOXYPHENYL)ETHYL 5-CHLORO-2,4-DIHYDROXYBENZOATE | n/a | |
| 33 | P08238_DB09221 | n/a | DB09221 | n/a | n/a | Polaprezinc | agonist |