P08246 ELNE_HUMAN
Gene name: ELANE
Protein name: Neutrophil elastase (EC

List of molecules and drugs that interact with protein P08246

#	DrugDomain Data	PBD ligand	DrugBank Accession	PubChem	ChEMBL	Name	Drug action	Affinity data
1	P08246_151	151	n/a	445970	n/a	(2S)-3-METHYL-2-((2R,3S)-3-[(METHYLSULFONYL)AMINO]-1-{[2-(PYRROLIDIN-1-YLMETHYL)-1,3-OXAZOL-4-YL]CARBONYL}PYRROLIDIN-2-YL)BUTANOIC ACID	n/a
2	P08246_2HY	2HY	n/a	11539563	CHEMBL1738716	2-hydroxyethyl (4R)-4-(4-cyanophenyl)-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrimidine-5-carboxylate	n/a
3	P08246_ACT	ACT	DB14511	175	n/a	ACETATE ION	n/a
4	P08246_BR	BR	n/a	259	n/a	BROMIDE ION	n/a
5	P08246_CL	CL	n/a	312	n/a	CHLORIDE ION	n/a
6	P08246_CQH	CQH	n/a	137349117	n/a	5-[[4-[[(2~{S})-4-methyl-1-oxidanylidene-1-[(2-propylphenyl)amino]pentan-2-yl]carbamoyl]phenyl]methyl]-2-oxidanylidene-1,3-thiazol-1-ium-4-olate	n/a
7	P08246_DMS	DMS	DB01093	679	CHEMBL504	DIMETHYL SULFOXIDE	n/a
8	P08246_EDO	EDO	n/a	174	CHEMBL457299	1,2-ETHANEDIOL	n/a
9	P08246_EPE	EPE	DB16872	23830;23831;3275884;	CHEMBL1232545	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	n/a
10	P08246_GOL	GOL	DB09462	753	CHEMBL692	GLYCEROL	n/a
11	P08246_HVP	HVP	n/a	138753605	n/a	2-(fluorosulfonyl)benzene-1-sulfonic acid	n/a
12	P08246_IUL	IUL	n/a	44480524	CHEMBL3642656	4-[(4R)-7-methyl-2,5-bis(oxidanylidene)-1-[3-(trifluoromethyl)phenyl]-3,4,6,8-tetrahydropyrimido[4,5-d]pyridazin-4-yl]benzenecarbonitrile	n/a
13	P08246_IUY	IUY	n/a	137349564	n/a	ethyl (5R)-5-(4-cyanophenyl)-7-methyl-8-[3-(trifluoromethyl)phenyl]-1,5-dihydroimidazo[1,2-a]pyrimidin-4-ium-6-carboxylate	n/a
14	P08246_JJD	JJD	n/a	59145670	CHEMBL3617969	2-[(4R)-4-(4-cyanophenyl)-5-ethanoyl-6-methyl-2-oxidanylidene-1-[3-(trifluoromethyl)phenyl]-4H-pyrimidin-3-yl]ethanoic acid	n/a
15	P08246_JJS	JJS	n/a	23728722	CHEMBL3617968	5-[(6R)-5-ethanoyl-4-methyl-2-oxidanylidene-3-[3-(trifluoromethyl)phenyl]-1,6-dihydropyrimidin-6-yl]pyridine-2-carbonitrile	n/a
16	P08246_JJV	JJV	n/a	42642360	CHEMBL3617972	(6S)-6-(4-cyano-2-methylsulfonyl-phenyl)-4-methyl-2-oxidanylidene-3-[3-(trifluoromethyl)phenyl]-1,6-dihydropyrimidine-5-carbonitrile	n/a
17	P08246_JJX	JJX	n/a	91827318	n/a	(4R)-4-(4-cyanophenyl)-6-methyl-2-oxidanylidene-3-[2-oxidanylidene-2-(4-propan-2-ylpiperazin-1-yl)ethyl]-1-[3-(trifluoromethyl)phenyl]-4H-pyrimidine-5-carbonitrile	n/a
18	P08246_LKK	LKK	n/a	146018267	n/a	3-[[1-[(4-bromophenyl)methyl]-1,2,3-triazol-4-yl]methylcarbamoyl]pentane-3-sulfonic acid	n/a
19	P08246_MES	MES	DB03814	78165;4478249;	CHEMBL1234276	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	n/a
20	P08246_MG	MG	n/a	888	n/a	MAGNESIUM ION	n/a
21	P08246_MLI	MLI	DB02201	9084	n/a	MALONATE ION	n/a
22	P08246_NAG	NAG	DB00141	24139	CHEMBL447878	2-acetamido-2-deoxy-beta-D-glucopyranose	n/a
23	P08246_SEI	SEI	DB02341	5289347	CHEMBL56852	1-{3-METHYL-2-[4-(MORPHOLINE-4-CARBONYL)-BENZOYLAMINO]-BUTYRYL}-PYRROLIDINE-2-CARBOXYLIC ACID (3,3,4,4,4-PENTAFLUORO-1-ISOPROPYL-2-OXO-BUTYL)-AMIDE	inhibitor
24	P08246_SO4	SO4	DB14546	1117	n/a	SULFATE ION	n/a
25	P08246_VBM	VBM	n/a	68432778	n/a	METHYL {(7R)-6-CYANO-7-(4-CYANOPHENYL)-5-METHYL-4-[3-(TRIFLUOROMETHYL)PHENYL]-4,7-DIHYDRO[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-YL}CARBAMATE	n/a
26	P08246_WQQ	WQQ	n/a	66725365	CHEMBL3617963	1-(3-CHLOROPHENYL)-5-(3,5-DIMETHYLISOXAZOL-4-YL)-6-METHYL-N-[4-(METHYLSULFONYL)BENZYL]-2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE	n/a
27	P08246_XPE	XPE	n/a	79689	n/a	3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL	n/a
28	P08246_DB02341	n/a	DB02341	n/a	n/a	Mdl 101,146	inhibitor
29	P08246_DB03925	n/a	DB03925	n/a	n/a	Freselestat	inhibitor
30	P08246_DB12622	n/a	DB12622	n/a	n/a	Lupeol	inhibitor
31	P08246_6Q5	6Q5	DB15588	64945	CHEMBL169	Ursolic acid	inhibitor