Gene name: MET
Protein name: Hepatocyte growth factor
List of molecules and drugs that interact with protein P08581
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P08581_03X | 03X | n/a | 56604907 | CHEMBL2031893 | N-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide | n/a | |
| 2 | P08581_044 | 044 | n/a | 24901693 | CHEMBL518174 | N-{3-fluoro-4-[(7-methoxyquinolin-4-yl)oxy]phenyl}-1-[(2R)-2-hydroxypropyl]-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide | n/a | |
| 3 | P08581_0J3 | 0J3 | n/a | 50997095 | CHEMBL1766528 | 3-(4-methylpiperazin-1-yl)-N-(3-nitrobenzyl)-7-(trifluoromethyl)quinolin-5-amine | n/a | |
| 4 | P08581_0J8 | 0J8 | n/a | 71449349 | CHEMBL2148143 | N-(3-nitrobenzyl)-6-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]-2-(trifluoromethyl)pyrido[2,3-d]pyrimidin-4-amine | n/a | |
| 5 | P08581_0JJ | 0JJ | n/a | 45487870 | CHEMBL566685 | 7-methoxy-N-{[6-(3-methyl-1,2-thiazol-5-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}-1,5-naphthyridin-4-amine | n/a | |
| 6 | P08581_0JK | 0JK | n/a | 44512602 | CHEMBL2029688 | 5-phenyl-3-(quinolin-6-ylmethyl)-3,5,6,7-tetrahydro-4H-[1,2,3]triazolo[4,5-c]pyridin-4-one | n/a | |
| 7 | P08581_0JL | 0JL | n/a | 44473400 | CHEMBL2029678 | 3-{(1S)-1-[3-(2-methoxyethoxy)quinolin-6-yl]ethyl}-5-(3-methyl-1,2-thiazol-5-yl)-3,5-dihydro-4H-[1,2,3]triazolo[4,5-c]pyridin-4-one | n/a | |
| 8 | P08581_1FN | 1FN | DB06896 | 21081761 | CHEMBL509101 | 1-(4-fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridine-3-carboxamide | n/a | IC50(nM) = 1.8 |
| 9 | P08581_1JC | 1JC | n/a | 71601483 | CHEMBL2323783 | 1-{5-oxo-3-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl}-N-(pyridin-2-ylmethyl)methanesulfonamide | n/a | |
| 10 | P08581_1RU | 1RU | n/a | 44194115 | CHEMBL2401813 | 7-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]furo[3,2-c]pyridin-6-amine | n/a | |
| 11 | P08581_319 | 319 | DB06995 | 17748441 | CHEMBL527066 | N-({4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}carbamoyl)-2-(4-fluorophenyl)acetamide | n/a | IC50(nM) = 35.0 |
| 12 | P08581_320 | 320 | DB06997 | 11560856 | CHEMBL503090 | 2-(4-fluorophenyl)-N-{[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]carbamoyl}acetamide | n/a | IC50(nM) = 110.0 |
| 13 | P08581_353 | 353 | DB12064 | 24794418 | CHEMBL460702 | N-{4-[(2-amino-3-chloropyridin-4-yl)oxy]-3-fluorophenyl}-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide | inhibitor | |
| 14 | P08581_3E8 | 3E8 | DB15133 | 25171648 | CHEMBL3402762 | 3-[1-(3-{5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl}benzyl)-6-oxo-1,6-dihydropyridazin-3-yl]benzonitrile | inhibitor | |
| 15 | P08581_3EH | 3EH | n/a | 45258276 | CHEMBL3402741 | 3-(diethylamino)propyl (3-{[5-(3,4-dimethoxyphenyl)-2-oxo-2H-1,3,4-thiadiazin-3(6H)-yl]methyl}phenyl)carbamate | n/a | |
| 16 | P08581_3QT | 3QT | n/a | 44206063 | CHEMBL1738731 | 6-{[6-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]methyl}quinoline | n/a | |
| 17 | P08581_44X | 44X | n/a | 118732962 | CHEMBL3414926 | 6-{(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(2-methoxyethoxy)quinoline | n/a | |
| 18 | P08581_46G | 46G | n/a | 118732959 | CHEMBL3414918 | 6-{(1R)-1-fluoro-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-methoxyquinoline | n/a | |
| 19 | P08581_4K0 | 4K0 | n/a | 70677398 | CHEMBL2170968 | 4-[3-(1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-6-yl]benzenecarbonitrile | n/a | |
| 20 | P08581_5B4 | 5B4 | n/a | 46208775 | n/a | N-(2,5-difluoro-4-{[2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxam ide | n/a | |
| 21 | P08581_5I9 | 5I9 | n/a | 164885928 | n/a | ~{N}1'-[3-fluoranyl-4-(10~{H}-pyrido[3,2-b][1,4]benzoxazin-4-yloxy)phenyl]-~{N}1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | n/a | |
| 22 | P08581_5IE | 5IE | n/a | 90644957 | CHEMBL3287591 | ~{N}1'-[3-fluoranyl-4-(2-phenylazanylpyrimidin-4-yl)oxy-phenyl]-~{N}1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | n/a | |
| 23 | P08581_5QQ | 5QQ | n/a | 127045762 | CHEMBL3797579 | 6-[bis(fluoranyl)-[6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl]methyl]quinoline | n/a | |
| 24 | P08581_5SZ | 5SZ | n/a | 44180127 | CHEMBL3786495 | 6-[(1~{R})-1-[8-fluoranyl-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one | n/a | |
| 25 | P08581_5T1 | 5T1 | DB15639 | 44181686 | CHEMBL3785909 | 6-[(1~{R})-1-[8-fluoranyl-6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(2-methoxyethoxy)-1,6-naphthyridin-5-one | modulator | |
| 26 | P08581_5TF | 5TF | n/a | 73294099 | CHEMBL2431816 | (S)-3-(1-(1H-pyrrolo(2,3-b)pyridin-3-yl)ethyl)-N-isopropyl-(1,2,4)triazolo(4,3-b)pyridazin-6-amine | n/a | |
| 27 | P08581_62E | 62E | n/a | 137348420 | CHEMBL4527749 | 1-[2-(1-ethylpiperidin-4-yl)ethyl]-3-(6-{[6-(thiophen-2-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}-1,3-benzothiazol-2-yl)urea | n/a | |
| 28 | P08581_63B | 63B | n/a | 91262312 | CHEMBL4453878 | methyl (6-{[6-(4-fluorophenyl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}-1H-benzimidazol-2-yl)carbamate | n/a | |
| 29 | P08581_63K | 63K | DB15382 | 25182860 | CHEMBL4461070 | 1-(6-{[6-(4-fluorophenyl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}-1,3-benzothiazol-2-yl)-3-[2-(morpholin-4-yl)ethyl]urea | inhibitor | |
| 30 | P08581_66L | 66L | n/a | 124080839 | n/a | N-[3-fluoro-4-({7-[2-(morpholin-4-yl)ethoxy]-1,6-naphthyridin-4-yl}oxy)phenyl]-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | n/a | |
| 31 | P08581_6TD | 6TD | n/a | 135653162 | CHEMBL4165354 | 2-[3-(4-methoxybenzyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]-1H-indole | n/a | |
| 32 | P08581_6XE | 6XE | n/a | 70677397 | CHEMBL2170967 | 6-[[6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl]methyl]quinoline | n/a | |
| 33 | P08581_6XP | 6XP | n/a | 72200766 | n/a | (2S)-N'-[(3R)-4-chloro-7-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl]-2-(4-hydroxyphenyl)propanehydrazide | n/a | |
| 34 | P08581_75H | 75H | n/a | 16757524 | CHEMBL445799 | N-{3-fluoro-4-[(7-methoxyquinolin-4-yl)oxy]phenyl}-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide | n/a | |
| 35 | P08581_7PE | 7PE | n/a | 526557 | n/a | 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL | n/a | |
| 36 | P08581_84M | 84M | n/a | 46174983 | n/a | N-{6-[([1,2,4]triazolo[4,3-a]pyridin-3-yl)sulfanyl]imidazo[1,2-b]pyridazin-2-yl}cyclopropanecarboxamide | n/a | |
| 37 | P08581_84P | 84P | n/a | 46175032 | n/a | N-(6-{[6-(1-methyl-1H-pyrazol-4-yl)-1H-benzotriazol-1-yl]methyl}imidazo[1,2-b]pyridazin-2-yl)cyclopropanecarboxamide | n/a | |
| 38 | P08581_84S | 84S | n/a | 56593558 | n/a | N-(6-{difluoro[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]methyl}imidazo[1,2-b]pyridazin-2-yl)cyclopropanecarboxamide | n/a | |
| 39 | P08581_88Z | 88Z | DB12307 | 42642645 | CHEMBL1230609 | N-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | modulator | |
| 40 | P08581_AM7 | AM7 | n/a | 11650194 | CHEMBL505896 | 2-benzyl-5-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-3-methylpyrimidin-4(3H)-one | n/a | |
| 41 | P08581_AM8 | AM8 | DB07369 | 17749728 | n/a | N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide | n/a | |
| 42 | P08581_ATP | ATP | DB00171 | 5957 | CHEMBL14249 | ADENOSINE-5'-TRIPHOSPHATE | n/a | |
| 43 | P08581_B2D | B2D | n/a | 25064730 | CHEMBL566875 | 7-methoxy-N-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]-1,5-naphthyridin-4-amine | n/a | |
| 44 | P08581_CKK | CKK | n/a | 21081523 | CHEMBL253881 | N-{[4-({5-[(4-aminopiperidin-1-yl)methyl]pyrrolo[2,1-f][1,2,4]triazin-4-yl}oxy)-3-fluorophenyl]carbamoyl}-2-(4-fluorophenyl)acetamide | n/a | |
| 45 | P08581_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 46 | P08581_DF6 | DF6 | n/a | 11525727 | CHEMBL205372 | N-({4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}carbamothioyl)-2-phenylacetamide | n/a | |
| 47 | P08581_DFQ | DFQ | n/a | 49866900 | n/a | (2E)-3-{6-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]quinolin-3-yl}-N-methylprop-2-enamide | n/a | |
| 48 | P08581_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 49 | P08581_DWF | DWF | n/a | 78673838 | CHEMBL3287310 | N-(3-fluoro-4-{[2-({3-[(methylsulfonyl)methyl]phenyl}amino)pyrimidin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | n/a | |
| 50 | P08581_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 51 | P08581_F47 | F47 | n/a | 11324689 | CHEMBL2170957 | 4-[[6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl]methyl]phenol | n/a | |
| 52 | P08581_FMT | FMT | DB01942 | 284;18971002; | CHEMBL116736 | FORMIC ACID | n/a | |
| 53 | P08581_GBL | GBL | DB04699 | 7302 | CHEMBL95681 | GAMMA-BUTYROLACTONE | n/a | |
| 54 | P08581_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 55 | P08581_I90 | I90 | n/a | 165430630 | CHEMBL5175646 | 2-[2-[3-(1-methylpyrazol-4-yl)quinolin-6-yl]ethyl]-6-(3-nitrophenyl)pyridazin-3-one | n/a | |
| 56 | P08581_I94 | I94 | n/a | 165430631 | CHEMBL5172104 | ~{N}-methyl-4-[1-[2-[3-(1-methylpyrazol-4-yl)quinolin-6-yl]ethyl]-6-oxidanylidene-pyridazin-3-yl]-2-(trifluoromethyl)benzamide | n/a | |
| 57 | P08581_IHX | IHX | DB07969 | 25113181 | CHEMBL462712 | 3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol | n/a | IC50(nM) = 900.0 |
| 58 | P08581_IOD | IOD | n/a | 30165 | n/a | IODIDE ION | n/a | |
| 59 | P08581_IPA | IPA | DB02325 | 3776 | CHEMBL582 | ISOPROPYL ALCOHOL | n/a | |
| 60 | P08581_KGL | KGL | n/a | 165437862 | CHEMBL5181396 | (1^4Z,5^2E)-6^3-(trifluoromethyl)-5^1,5^6-dihydro-1^1H-8-aza-2(3,6)-quinolina-5(1,3)-pyridazina-1(4,1)-pyrazola-6(1,4)-benzenacyclododecaphane-5^6,7-dione | n/a | |
| 61 | P08581_KRW | KRW | DB12848 | 17754438 | CHEMBL2001019 | 2-{4-[1-(QUINOLIN-6-YLMETHYL)-1H-[1,2,3]TRIAZOLO[4,5-B]PYRAZIN-6-YL]-1H-PYRAZOL-1-YL}ETHANOL | inhibitor | |
| 62 | P08581_KSA | KSA | DB02152 | 3035817 | CHEMBL281948 | K-252A | n/a | |
| 63 | P08581_L1X | L1X | DB12381 | 44603533 | CHEMBL3545307 | N-(3-fluoro-4-{[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy}phenyl)-1-(4-fluorophenyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide | modulator | |
| 64 | P08581_L5G | L5G | DB08079 | 24864821 | CHEMBL496102 | 7-methoxy-4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline | inhibitor | IC50(nM) = 9.0 |
| 65 | P08581_L8V | L8V | n/a | 16223106 | CHEMBL1097142 | 2-({4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}amino)-N-(2,4-difluorophenyl)pyridine-3-carboxamide | n/a | |
| 66 | P08581_LKG | LKG | DB08111 | 24901696 | CHEMBL495898 | 4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]phenol | n/a | IC50(nM) = 120.0 |
| 67 | P08581_M61 | M61 | n/a | 56593141 | CHEMBL1802917 | N-[(2R)-1,4-dioxan-2-ylmethyl]-N-methyl-N'-{5-oxo-3-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl}sulfuric diamide | n/a | |
| 68 | P08581_M97 | M97 | n/a | 53322946 | n/a | 1-[(3R,4R)-4-(1H-indol-3-yl)-2,5-dioxopyrrolidin-3-yl]pyrrolo[3,2,1-ij]quinolinium | n/a | |
| 69 | P08581_MDI | MDI | n/a | 164885962 | CHEMBL5272595 | 3-[bis(fluoranyl)methyl]-~{N}-methyl-~{N}-[(1~{R})-8-methyl-5-(3-methyl-1~{H}-indazol-6-yl)-1,2,3,4-tetrahydronaphthalen-1-yl]pyridine-2-carboxamide | n/a | |
| 70 | P08581_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 71 | P08581_MT3 | MT3 | n/a | 11857432 | CHEMBL461648 | 2-benzyl-5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-3-methylpyrimidin-4(3H)-one | n/a | |
| 72 | P08581_MT4 | MT4 | n/a | 11857949 | CHEMBL461831 | 5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-2-[(4-fluorophenyl)amino]-3-methylpyrimidin-4(3H)-one | n/a | |
| 73 | P08581_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 74 | P08581_NAG | NAG | DB00141 | 24139 | CHEMBL447878 | 2-acetamido-2-deoxy-beta-D-glucopyranose | n/a | |
| 75 | P08581_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 76 | P08581_PFY | PFY | n/a | 49867491 | n/a | (3Z)-5-[(2,6-DICHLOROBENZYL)SULFONYL]-3-[(3,5-DIMETHYL-4-{[(2S)-2-(PYRROLIDIN-1-YLMETHYL)PYRROLIDIN-1-YL]CARBONYL}-1H-PYRROL-2-YL)METHYLIDENE]-1,3-DIHYDRO-2H-INDOL-2-ONE | n/a | |
| 77 | P08581_PG4 | PG4 | n/a | 8200 | CHEMBL1235254 | TETRAETHYLENE GLYCOL | n/a | |
| 78 | P08581_Q6W | Q6W | n/a | 49837887 | CHEMBL1615181 | 3-{5-oxo-3-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl}-N-(pyridin-2-ylmethyl)propanamide | n/a | |
| 79 | P08581_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 80 | P08581_V0L | V0L | DB12048 | 68289010 | CHEMBL3334567 | volitinib | inhibitor | |
| 81 | P08581_VGH | VGH | DB08865 | 11626560 | CHEMBL601719 | 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-amine | inhibitor | |
| 82 | P08581_W3N | W3N | n/a | 168355721 | n/a | 1-[(1S)-1-[3-(1H-imidazol-4-yl)phenyl]ethyl]-5-(1H-indazol-7-yl)pyrimidine-2,4-dione | n/a | |
| 83 | P08581_W3R | W3R | n/a | 168355719 | n/a | 5-(1H-indazol-7-yl)-1-[(1S)-1-phenylethyl]pyrimidine-2,4-dione | n/a | |
| 84 | P08581_W3W | W3W | n/a | 168355720 | n/a | 5-[3,5-bis(fluoranyl)phenyl]-1-[(1S)-1-[3-(1H-imidazol-5-yl)phenyl]ethyl]pyrimidine-2,4-dione | n/a | |
| 85 | P08581_W40 | W40 | n/a | 168355722 | CHEMBL5418424 | 5-[3,5-bis(fluoranyl)phenyl]-1-[(1S)-1-phenylethyl]pyrimidine-2,4-dione | n/a | |
| 86 | P08581_W49 | W49 | n/a | 168355718 | CHEMBL5431153 | 5-(3-ethynyl-5-fluoranyl-1H-indazol-7-yl)-1-[(1S)-1-phenylethyl]pyrimidine-2,4-dione | n/a | |
| 87 | P08581_W9Z | W9Z | n/a | 24871823 | CHEMBL2431819 | 6-{(1S)-1-[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]ethyl}quinoline | n/a | |
| 88 | P08581_ZZY | ZZY | DB08791 | 25229537 | CHEMBL561660 | 1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE | n/a | IC50(nM) = 82.0 |
| 89 | P08581_SV5 | SV5 | n/a | 14114385 | CHEMBL4796728 | 1-(phenylmethyl)-5~{H}-pyrrolo[3,2-c]pyridin-4-one | n/a | |
| 90 | P08581_SV8 | SV8 | n/a | 155804537 | CHEMBL4747073 | 3-[3-(phenylmethyl)-1~{H}-pyrrolo[2,3-b]pyridin-5-yl]-4,5-dihydro-1~{H}-pyrrolo[3,4-b]pyrrol-6-one | n/a | |
| 91 | P08581_SVH | SVH | n/a | 155804538 | CHEMBL4743552 | 3-(6-fluoranyl-1~{H}-indazol-4-yl)-4,5-dihydro-1~{H}-pyrrolo[3,4-b]pyrrol-6-one | n/a | |
| 92 | P08581_SVK | SVK | n/a | 21028223 | CHEMBL4744343 | 3-(phenylmethyl)-1~{H}-pyrrolo[2,3-b]pyridine | n/a | |
| 93 | P08581_SVT | SVT | n/a | 13346860 | CHEMBL15739 | 5-methoxy-1~{H}-indazole | n/a | |
| 94 | P08581_SW5 | SW5 | n/a | 155289351 | CHEMBL4792886 | 3-[(4-fluorophenyl)methyl]-5-(1-piperidin-4-ylpyrazol-4-yl)-1~{H}-pyrrolo[2,3-b]pyridine | n/a | |
| 95 | P08581_SW8 | SW8 | n/a | 155289350 | CHEMBL4749560 | 3-[(3-fluorophenyl)methyl]-5-(1-piperidin-4-ylpyrazol-4-yl)-1~{H}-pyrrolo[2,3-b]pyridine | n/a | |
| 96 | P08581_SWB | SWB | n/a | 155804539 | CHEMBL4748121 | 3-(3-methyl-1~{H}-pyrrolo[2,3-b]pyridin-5-yl)-1~{H}-pyrrolo[3,4-b]pyrrol-6-one | n/a | |
| 97 | P08581_SWK | SWK | n/a | 155289349 | CHEMBL4796908 | 3-[(2-fluorophenyl)methyl]-5-(1-piperidin-4-ylpyrazol-4-yl)-1~{H}-pyrrolo[2,3-b]pyridine | n/a | |
| 98 | P08581_SWN | SWN | n/a | 155289348 | CHEMBL4784342 | 3-(phenylmethyl)-5-(1-piperidin-4-ylpyrazol-4-yl)-1~{H}-pyrrolo[2,3-b]pyridine | n/a | |
| 99 | P08581_SX8 | SX8 | DB06314 | 24779724 | CHEMBL1236107 | 6-{[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline | inhibitor | |
| 100 | P08581_B49 | B49 | DB01268 | 5329102 | CHEMBL535 | Sunitinib | inhibitor | IC50(nM) = 5000.0 Kd(nM) = 1200.0 |
| 101 | P08581_DB08875 | n/a | DB08875 | n/a | n/a | Cabozantinib | antagonist | |
| 102 | P08581_DB11791 | n/a | DB11791 | n/a | n/a | Capmatinib | inhibitor | |
| 103 | P08581_AV9 | AV9 | DB11800 | 9911830 | CHEMBL1289494 | Tivozanib | inhibitor | |
| 104 | P08581_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor | |
| 105 | P08581_TIV | TIV | DB12200 | 11494412 | CHEMBL2103882 | Tivantinib | inhibitor | |
| 106 | P08581_6GY | 6GY | DB12267 | 68165256 | CHEMBL3545311 | Brigatinib | inhibitor | |
| 107 | P08581_DB12742 | n/a | DB12742 | n/a | n/a | Amuvatinib | n/a |