Gene name: CHRM5
Protein name: Muscarinic acetylcholine receptor
List of molecules and drugs that interact with protein P08912
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P08912_0HK | 0HK | DB01409 | n/a | CHEMBL1900528 | (1R,2R,4S,5S,7S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane | n/a | |
| 2 | P08912_OLA | OLA | n/a | 445639 | CHEMBL8659 | OLEIC ACID | n/a | |
| 3 | P08912_OLC | OLC | n/a | 11451146 | n/a | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | n/a | |
| 4 | P08912_P33 | P33 | DB03394 | 79718 | n/a | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL | n/a | |
| 5 | P08912_DB00246 | n/a | DB00246 | n/a | n/a | Ziprasidone | antagonist | Ki(nM) = 1600.0 |
| 6 | P08912_DB00342 | n/a | DB00342 | n/a | n/a | Terfenadine | binder | |
| 7 | P08912_DB00363 | n/a | DB00363 | n/a | n/a | Clozapine | antagonist | |
| 8 | P08912_DB00376 | n/a | DB00376 | n/a | n/a | Trihexyphenidyl | antagonist | Ki(nM) = 5.01 IC50(nM) = 10.0 |
| 9 | P08912_DB00408 | n/a | DB00408 | n/a | n/a | Loxapine | binder | Ki(nM) = 241.0 |
| 10 | P08912_IXX | IXX | DB00458 | 3696 | CHEMBL11 | Imipramine | antagonist | Ki(nM) = 83.0 |
| 11 | P08912_DB00483 | n/a | DB00483 | n/a | n/a | Gallamine triethiodide | n/a | |
| 12 | P08912_DB00496 | n/a | DB00496 | n/a | n/a | Darifenacin | antagonist | Ki(nM) = 2.3 |
| 13 | P08912_DB00572 | n/a | DB00572 | n/a | n/a | Atropine | antagonist | Ki(nM) = 0.4 |
| 14 | P08912_DB00622 | n/a | DB00622 | n/a | n/a | Nicardipine | antagonist | |
| 15 | P08912_DB00725 | n/a | DB00725 | n/a | n/a | Homatropine methylbromide | antagonist | |
| 16 | P08912_DB00747 | n/a | DB00747 | n/a | n/a | Scopolamine | antagonist | |
| 17 | P08912_DB00767 | n/a | DB00767 | n/a | n/a | Benzquinamide | antagonist | |
| 18 | P08912_DB00835 | n/a | DB00835 | n/a | n/a | Brompheniramine | antagonist | |
| 19 | P08912_DB00934 | n/a | DB00934 | n/a | n/a | Maprotiline | antagonist | |
| 20 | P08912_DB00940 | n/a | DB00940 | n/a | n/a | Methantheline | antagonist | |
| 21 | P08912_DB00986 | n/a | DB00986 | n/a | n/a | Glycopyrronium | antagonist | IC50(nM) = 0.2 |
| 22 | P08912_DB01019 | n/a | DB01019 | n/a | n/a | Bethanechol | agonist | |
| 23 | P08912_DB01036 | n/a | DB01036 | n/a | n/a | Tolterodine | antagonist | Ki(nM) = 2.2 |
| 24 | P08912_DB01069 | n/a | DB01069 | n/a | n/a | Promethazine | antagonist | |
| 25 | P08912_DB01142 | no_lig_id | DB01142 | n/a | n/a | Doxepin | antagonist | |
| 26 | P08912_DSM | DSM | DB01151 | 2995 | CHEMBL72 | Desipramine | antagonist | Ki(nM) = 143.0 |
| 27 | P08912_DB01224 | n/a | DB01224 | n/a | n/a | Quetiapine | ligand | Ki(nM) = 2990.0 |
| 28 | P08912_9SC | 9SC | DB01238 | 60795 | CHEMBL1112 | Aripiprazole | ligand | Ki(nM) = 2330.0 |
| 29 | P08912_DB01239 | n/a | DB01239 | n/a | n/a | Chlorprothixene | antagonist | |
| 30 | P08912_DB01403 | n/a | DB01403 | n/a | n/a | Methotrimeprazine | antagonist | |
| 31 | P08912_DB01591 | n/a | DB01591 | n/a | n/a | Solifenacin | antagonist | Ki(nM) = 44.0 |
| 32 | P08912_DB06702 | n/a | DB06702 | n/a | n/a | Fesoterodine | antagonist | |
| 33 | P08912_DB06709 | n/a | DB06709 | n/a | n/a | Methacholine | agonist | |
| 34 | P08912_DB08897 | n/a | DB08897 | n/a | n/a | Aclidinium | antagonist | IC50(nM) = 0.158 |
| 35 | P08912_DB09076 | n/a | DB09076 | n/a | n/a | Umeclidinium | antagonist | |
| 36 | P08912_DB09167 | n/a | DB09167 | n/a | n/a | Dosulepin | antagonist | |
| 37 | P08912_DB11181 | n/a | DB11181 | n/a | n/a | Homatropine | antagonist | |
| 38 | P08912_DB11235 | n/a | DB11235 | n/a | n/a | Thonzylamine | antagonist | |
| 39 | P08912_DB12278 | n/a | DB12278 | n/a | n/a | Propiverine | antagonist | |
| 40 | P08912_DB13581 | n/a | DB13581 | n/a | n/a | Rociverine | antagonist | |
| 41 | P08912_DB14185 | n/a | DB14185 | n/a | n/a | Aripiprazole lauroxil | n/a |