Gene name: ROS1
Protein name: Proto-oncogene tyrosine-protein kinase
List of molecules and drugs that interact with protein P08922
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P08922_5P8 | 5P8 | DB12130 | 71731823 | CHEMBL3286830 | (10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile | inhibitor | |
| 2 | P08922_AWJ | AWJ | n/a | 137348958 | n/a | (2R)-2-[5-(6-amino-5-{(1R)-1-[2-(1,3-dihydro-2H-1,2,3-triazol-2-yl)-5-fluorophenyl]ethoxy}pyridin-3-yl)-4-methyl-1,3-thiazol-2-yl]propane-1,2-diol | n/a | |
| 3 | P08922_IDW | IDW | n/a | 87663169 | n/a | ~{N}-[6-methyl-2-[(2~{S})-2-[3-(3-methylpyrazin-2-yl)-1,2-oxazol-5-yl]pyrrolidin-1-yl]pyrimidin-4-yl]-1,3-thiazol-2-amine | n/a | |
| 4 | P08922_VGH | VGH | DB08865 | 11626560 | CHEMBL601719 | 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-amine | inhibitor | |
| 5 | P08922_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 6 | P08922_YMX | YMX | DB11986 | 25141092 | CHEMBL1983268 | Entrectinib | inhibitor | |
| 7 | P08922_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor |