Gene name: PDGFRB
Protein name: Platelet-derived growth factor
List of molecules and drugs that interact with protein P09619
# | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
---|---|---|---|---|---|---|---|---|
1 | P09619_NAG | NAG | DB00141 | 24139 | CHEMBL447878 | 2-acetamido-2-deoxy-beta-D-glucopyranose | n/a | |
2 | P09619_NDG | NDG | DB03740 | 82313 | CHEMBL1234669 | 2-acetamido-2-deoxy-alpha-D-glucopyranose | n/a | |
3 | P09619_BAX | BAX | DB00398 | 216239 | CHEMBL1336 | Sorafenib | inhibitor | IC50(nM) = 0.26 Kd(nM) = 37.0 |
4 | P09619_STI | STI | DB00619 | 5291 | CHEMBL941 | Imatinib | antagonist | Ki(nM) = 3.0 IC50(nM) = 50.0 Kd(nM) = 14.0 |
5 | P09619_1N1 | 1N1 | DB01254 | 3062316 | CHEMBL1421 | Dasatinib | antagonist | IC50(nM) = 28.0 Kd(nM) = 0.63 |
6 | P09619_B49 | B49 | DB01268 | 5329102 | CHEMBL535 | Sunitinib | inhibitor | Ki(nM) = 8.0 IC50(nM) = 2.0 Kd(nM) = 0.075 |
7 | P09619_DB06589 | n/a | DB06589 | n/a | n/a | Pazopanib | inhibitor | IC50(nM) = 83.0 Kd(nM) = 2.0 |
8 | P09619_2K2 | 2K2 | DB06595 | 9829523 | CHEMBL608533 | Midostaurin | antagonist | |
9 | P09619_DB08896 | n/a | DB08896 | n/a | n/a | Regorafenib | inhibitor | IC50(nM) = 1.5 |
10 | P09619_XIN | XIN | DB09079 | 9809715 | CHEMBL502835 | Nintedanib | inhibitor | |
11 | P09619_DB09221 | n/a | DB09221 | n/a | n/a | Polaprezinc | agonist | |
12 | P09619_K1S | K1S | DB09283 | 5531 | CHEMBL132767 | Trapidil | antagonist | |
13 | P09619_AV9 | AV9 | DB11800 | 9911830 | CHEMBL1289494 | Tivozanib | inhibitor | |
14 | P09619_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor | |
15 | P09619_5SF | 5SF | DB12147 | 67462786 | CHEMBL3545376 | Erdafitinib | substrate | |
16 | P09619_P31 | P31 | DB12978 | 25151352 | CHEMBL3813873 | Pexidartinib | inhibitor | |
17 | P09619_DB14840 | n/a | DB14840 | n/a | n/a | Ripretinib | inhibitor | |
18 | P09619_Q4J | Q4J | DB15822 | n/a | CHEMBL4297597 | Pralsetinib | inhibitor |