Gene name: ALOX5
Protein name: Polyunsaturated fatty acid
List of molecules and drugs that interact with protein P09917
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P09917_30Z | 30Z | n/a | 688035 | CHEMBL4756087 | 4-[(2R,3S)-3-[(3,4-DIHYDROXYPHENYL)METHYL]-2-METHYLBUTYL]BENZENE-1,2-DIOL | n/a | |
| 2 | P09917_ACD | ACD | DB04557 | 444899 | CHEMBL15594 | ARACHIDONIC ACID | n/a | |
| 3 | P09917_AF7 | AF7 | n/a | 11168203 | CHEMBL237111 | (3alpha,8alpha,17alpha,18alpha)-3-(acetyloxy)-11-oxours-12-en-23-oic acid | n/a | |
| 4 | P09917_FE2 | FE2 | n/a | 27284 | n/a | FE (II) ION | n/a | |
| 5 | P09917_EPA | EPA | DB00159 | 446284 | CHEMBL460026 | Icosapent | substrate | |
| 6 | P09917_VIV | VIV | DB00163 | 14985 | CHEMBL47 | Vitamin E | n/a | |
| 7 | P09917_DB00179 | n/a | DB00179 | n/a | n/a | Masoprocol | inhibitor | IC50(nM) = 25.0 EC50(nM) = 330000.0 |
| 8 | P09917_BHA | BHA | DB00233 | 4649 | CHEMBL1169 | Aminosalicylic acid | inhibitor | |
| 9 | P09917_DB00244 | n/a | DB00244 | n/a | n/a | Mesalazine | inhibitor | |
| 10 | P09917_MTK | MTK | DB00471 | 5281040 | CHEMBL787 | Montelukast | other/unknown | |
| 11 | P09917_DB00711 | n/a | DB00711 | n/a | n/a | Diethylcarbamazine | inhibitor | |
| 12 | P09917_DB00744 | n/a | DB00744 | n/a | n/a | Zileuton | inhibitor | IC50(nM) = 100.0 EC50(nM) = 470.0 |
| 13 | P09917_SAS | SAS | DB00795 | n/a | CHEMBL421 | Sulfasalazine | inhibitor | |
| 14 | P09917_JMS | JMS | DB00939 | 4037 | CHEMBL509 | Meclofenamic acid | inhibitor | |
| 15 | P09917_DB01014 | n/a | DB01014 | n/a | n/a | Balsalazide | inhibitor | |
| 16 | P09917_MIY | MIY | DB01017 | n/a | CHEMBL1434 | Minocycline | inhibitor | |
| 17 | P09917_DB01892 | n/a | DB01892 | n/a | n/a | Hyperforin | inhibitor | |
| 18 | P09917_STL | STL | DB02709 | 445154 | CHEMBL165 | Resveratrol | n/a | IC50(nM) = 4900.0 |
| 19 | P09917_LCF | LCF | DB04725 | 133021 | CHEMBL300982 | Licofelone | inhibitor | IC50(nM) = 180.0 |
| 20 | P09917_DB05431 | n/a | DB05431 | n/a | n/a | MLN-977 | inhibitor | |
| 21 | P09917_DB09285 | n/a | DB09285 | n/a | n/a | Morniflumate | antagonist | |
| 22 | P09917_DB11994 | n/a | DB11994 | n/a | n/a | Diacerein | inhibitor | |
| 23 | P09917_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor | |
| 24 | P09917_RHN | RHN | DB13174 | 10168 | CHEMBL418068 | Rhein | inhibitor | |
| 25 | P09917_DB14001 | n/a | DB14001 | n/a | n/a | alpha-Tocopherol succinate | n/a | |
| 26 | P09917_DB14002 | n/a | DB14002 | n/a | n/a | D-alpha-Tocopherol acetate | n/a |