Gene name: AR
Protein name: Androgen receptor (Dihydrotestosterone
List of molecules and drugs that interact with protein P10275
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P10275_056 | 056 | n/a | 53239919 | n/a | 3-[(2,4-DICHLOROPHENYL)METHYLSULFANYLMETHYL]BENZOIC ACID | n/a | |
| 2 | P10275_17H | 17H | DB06870 | 6857686 | CHEMBL1229684 | 17-HYDROXY-18A-HOMO-19-NOR-17ALPHA-PREGNA-4,9,11-TRIEN-3-ONE | n/a | |
| 3 | P10275_17W | 17W | n/a | 1944110 | CHEMBL1563710 | 2-[(2-phenoxyethyl)sulfanyl]-1H-benzimidazole | n/a | |
| 4 | P10275_198 | 198 | DB02932 | 56069 | CHEMBL63560 | R-BICALUTAMIDE | n/a | Ki(nM) = 11.0 IC50(nM) = 120.23 |
| 5 | P10275_2MI | 2MI | n/a | 7224 | CHEMBL259419 | 2-METHYL-1H-INDOLE | n/a | |
| 6 | P10275_30Z | 30Z | n/a | 688035 | CHEMBL4756087 | 4-[(2R,3S)-3-[(3,4-DIHYDROXYPHENYL)METHYL]-2-METHYLBUTYL]BENZENE-1,2-DIOL | n/a | |
| 7 | P10275_3B6 | 3B6 | DB07039 | 24892823 | n/a | (2S)-N-(4-cyano-3-iodophenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide | n/a | |
| 8 | P10275_3E0 | 3E0 | n/a | 91824269 | n/a | 4-[4-(3-fluoro-2-methoxyphenyl)-1,3-thiazol-2-yl]morpholine | n/a | |
| 9 | P10275_4HY | 4HY | DB03604 | 5803 | CHEMBL41632 | [4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID | n/a | IC50(nM) = 34800.0 |
| 10 | P10275_51Y | 51Y | n/a | 71543393 | CHEMBL3764185 | 2-chloro-4-{[(1R,2R)-2-hydroxy-2-methylcyclopentyl]amino}-3-methylbenzonitrile | n/a | |
| 11 | P10275_77T | 77T | n/a | 24986664 | CHEMBL4092535 | 2-fluoro-4-[(2S,3S)-3-hydroxy-2,3-dimethylpyrrolidin-1-yl]-3-methylbenzonitrile | n/a | |
| 12 | P10275_77U | 77U | n/a | 59370500 | CHEMBL4090028 | 2-chloro-4-[(2S,3S)-3-hydroxy-2-methylpyrrolidin-1-yl]-3-methylbenzonitrile | n/a | |
| 13 | P10275_97A | 97A | n/a | 59556974 | CHEMBL4088914 | 4-[(2S,3S)-2-ethyl-3-hydroxy-5-oxopyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile | n/a | |
| 14 | P10275_9FG | 9FG | n/a | 132471744 | CHEMBL4095883 | 5-(2-fluoro-4-hydroxyphenyl)-1-methyl-1H-pyrrole-2-carbonitrile | n/a | |
| 15 | P10275_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 16 | P10275_AV6 | AV6 | n/a | 761631 | CHEMBL1822156 | 4-(2,3-dihydro-1H-perimidin-2-yl)benzene-1,2-diol | n/a | |
| 17 | P10275_B5R | B5R | DB07419 | 24892822 | CHEMBL512283 | (2S)-3-(4-chloro-3-fluorophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide | n/a | Ki(nM) = 1.7 |
| 18 | P10275_B66 | B66 | DB07421 | 46937071 | n/a | 4-{[(1R,2S)-1,2-dihydroxy-2-methyl-3-(4-nitrophenoxy)propyl]amino}-2-(trifluoromethyl)benzonitrile | n/a | |
| 19 | P10275_B67 | B67 | DB07422 | 10174090 | CHEMBL124493 | (2S)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-(pentafluorophenoxy)propanamide | n/a | |
| 20 | P10275_B68 | B68 | DB07423 | 9824562 | CHEMBL125236 | (2S)-3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide | agonist | Ki(nM) = 4.0 |
| 21 | P10275_BHM | BHM | DB07454 | 5287785 | CHEMBL296323 | (R)-3-BROMO-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE | n/a | Ki(nM) = 0.3 |
| 22 | P10275_CA4 | CA4 | DB04839 | 9880 | CHEMBL139835 | CYPROTERONE ACETATE | antagonist | Ki(nM) = 14.0 IC50(nM) = 23.0 |
| 23 | P10275_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 24 | P10275_DHT | DHT | DB02901 | 10635 | CHEMBL27769 | 5-ALPHA-DIHYDROTESTOSTERONE | agonist | |
| 25 | P10275_DTT | DTT | DB04447 | 439196 | CHEMBL406270 | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | n/a | |
| 26 | P10275_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 27 | P10275_ENM | ENM | DB07717 | 16750073 | CHEMBL485835 | (5S,8R,9S,10S,13R,14S,17S)-13-{2-[(3,5-DIFLUOROBENZYL)OXY]ETHYL}-17-HYDROXY-10-METHYLHEXADECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-3-ONE | n/a | |
| 28 | P10275_EPE | EPE | DB16872 | 23830;23831;3275884; | CHEMBL1232545 | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | n/a | |
| 29 | P10275_FHM | FHM | DB07769 | 5288215 | CHEMBL124718 | S-3-(4-FLUOROPHENOXY)-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE | n/a | Ki(nM) = 6.1 |
| 30 | P10275_FLF | FLF | DB02266 | 3371 | CHEMBL23588 | 2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID | inhibitor | IC50(nM) = 50000.0 EC50(nM) = 67000.0 |
| 31 | P10275_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 32 | P10275_HFT | HFT | DB00499 | 91649 | CHEMBL491 | HYDROXYFLUTAMIDE | antagonist | Ki(nM) = 1300.0 IC50(nM) = 154.0 |
| 33 | P10275_ICO | ICO | n/a | 69867 | CHEMBL387527 | 1H-INDOLE-3-CARBOXYLIC ACID | n/a | |
| 34 | P10275_IMD | IMD | DB03366 | 444234;4434133;21983501; | n/a | IMIDAZOLE | n/a | |
| 35 | P10275_JAD | JAD | n/a | 71239417 | CHEMBL3326454 | 2-chloro-4-[(3S,3aS,4S)-4-hydroxy-3-methoxy-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-b]pyrazol-2-yl]-3-methylbenzonitrile | n/a | |
| 36 | P10275_K10 | K10 | DB08035 | 11522441 | CHEMBL411930 | 1-TERT-BUTYL-3-(2,5-DIMETHYLBENZYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE | n/a | |
| 37 | P10275_LGD | LGD | DB08089 | 11560224 | CHEMBL436784 | 6-[BIS(2,2,2-TRIFLUOROETHYL)AMINO]-4-(TRIFLUOROMETHYL)QUINOLIN-2(1H)-ONE | inhibitor | Ki(nM) = 1.0 EC50(nM) = 0.2 |
| 38 | P10275_LI | LI | n/a | 28486 | CHEMBL1234004 | LITHIUM ION | n/a | |
| 39 | P10275_MES | MES | DB03814 | 78165;4478249; | CHEMBL1234276 | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | n/a | |
| 40 | P10275_MXD | MXD | DB00350 | n/a | CHEMBL802 | 6-PIPERIDIN-1-YLPYRIMIDINE-2,4-DIAMINE 3-OXIDE | n/a | |
| 41 | P10275_NK | NK | n/a | 6998 | CHEMBL108925 | SALICYLALDEHYDE | n/a | |
| 42 | P10275_PGE | PGE | DB02327 | 8172 | CHEMBL1235259 | TRIETHYLENE GLYCOL | n/a | |
| 43 | P10275_PK0 | PK0 | n/a | 24811980 | CHEMBL2177238 | 4-[(4R)-4-(4-hydroxyphenyl)-3,4-dimethyl-2,5-dioxoimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile | n/a | |
| 44 | P10275_PK1 | PK1 | n/a | 59235249 | CHEMBL2177230 | (5R)-3-(3,4-dichlorophenyl)-5-(4-hydroxyphenyl)-1,5-dimethyl-2-thioxoimidazolidin-4-one | n/a | |
| 45 | P10275_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 46 | P10275_R18 | R18 | DB02998 | 261000 | CHEMBL166444 | (17BETA)-17-HYDROXY-17-METHYLESTRA-4,9,11-TRIEN-3-ONE | activator | Ki(nM) = 0.4 IC50(nM) = 0.302 Kd(nM) = 0.52 EC50(nM) = 0.013 |
| 47 | P10275_RB1 | RB1 | DB08461 | 16750071 | CHEMBL259420 | 3-[(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)METHYL]PHENOL | n/a | |
| 48 | P10275_RLJ | RLJ | DB12078 | 11326715 | CHEMBL1738889 | (2S)-3-(4-cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide | n/a | |
| 49 | P10275_RLL | RLL | n/a | 51346204 | CHEMBL1738890 | (2S)-3-[(4-cyanonaphthalen-1-yl)oxy]-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide | n/a | |
| 50 | P10275_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 51 | P10275_TES | TES | DB00624 | 6013 | CHEMBL386630 | TESTOSTERONE | agonist | Ki(nM) = 3.2 IC50(nM) = 2.7 Kd(nM) = 0.4 EC50(nM) = 1.1 |
| 52 | P10275_YLO | YLO | n/a | 3114779 | CHEMBL1738936 | 1-[2-(4-METHYLPHENOXY)ETHYL]-2-(2-PHENOXYETHYLSULFANYL)BENZIMIDAZOLE | n/a | |
| 53 | P10275_YLQ | YLQ | n/a | 2772641 | CHEMBL1738937 | 3-[1-[2-(4-METHYLPHENOXY)ETHYL]BENZIMIDAZOL-2-YL]SULFANYLPROPANOIC ACID | n/a | |
| 54 | P10275_ZK5 | ZK5 | DB00687 | 31378 | CHEMBL1201388 | 9ALPHA-FLUOROCORTISOL | inhibitor | |
| 55 | P10275_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 56 | P10275_T3 | T3 | DB00279 | 5920;7048703; | CHEMBL1544 | 3,5,3'TRIIODOTHYRONINE | n/a | IC50(nM) = 50000.0 |
| 57 | P10275_DES | DES | DB00255 | 448537 | CHEMBL411 | Diethylstilbestrol | antagonist | |
| 58 | P10275_NOG | NOG | DB00367 | 13109 | CHEMBL1389 | Levonorgestrel | binder | |
| 59 | P10275_STR | STR | DB00396 | 5994 | CHEMBL103 | Progesterone | agonist | Ki(nM) = 8.5 IC50(nM) = 14.0 |
| 60 | P10275_SNL | SNL | DB00421 | 5833 | CHEMBL1393 | Spironolactone | antagonist | Ki(nM) = 39.4 IC50(nM) = 48.0 EC50(nM) = 20000.0 |
| 61 | P10275_DB00499 | n/a | DB00499 | n/a | n/a | Flutamide | antagonist | Ki(nM) = 1300.0 IC50(nM) = 154.0 |
| 62 | P10275_DB00621 | n/a | DB00621 | n/a | n/a | Oxandrolone | agonist | |
| 63 | P10275_DB00623 | n/a | DB00623 | n/a | n/a | Fluphenazine | n/a | |
| 64 | P10275_DB00648 | n/a | DB00648 | n/a | n/a | Mitotane | antagonist | |
| 65 | P10275_J3Z | J3Z | DB00655 | 5870 | CHEMBL1405 | Estrone | n/a | |
| 66 | P10275_DB00665 | n/a | DB00665 | n/a | n/a | Nilutamide | antagonist | IC50(nM) = 9.0 |
| 67 | P10275_CTX | CTX | DB00675 | 2733526 | CHEMBL83 | Tamoxifen | n/a | |
| 68 | P10275_NDR | NDR | DB00717 | 6230 | CHEMBL1162 | Norethisterone | agonist | |
| 69 | P10275_DB00858 | n/a | DB00858 | n/a | n/a | Drostanolone | agonist | |
| 70 | P10275_DB00957 | n/a | DB00957 | n/a | n/a | Norgestimate | partial agonist | |
| 71 | P10275_DB00984 | n/a | DB00984 | n/a | n/a | Nandrolone phenpropionate | agonist | |
| 72 | P10275_DB01026 | n/a | DB01026 | n/a | n/a | Ketoconazole | binder | |
| 73 | P10275_DB01063 | n/a | DB01063 | n/a | n/a | Acetophenazine | n/a | |
| 74 | P10275_DB01128 | n/a | DB01128 | n/a | n/a | Bicalutamide | antagonist | Ki(nM) = 11.0 IC50(nM) = 10.0 EC50(nM) = 157.0 |
| 75 | P10275_DB01185 | n/a | DB01185 | n/a | n/a | Fluoxymesterone | agonist | Ki(nM) = 5.7 EC50(nM) = 0.3 |
| 76 | P10275_DB01395 | n/a | DB01395 | n/a | n/a | Drospirenone | antagonist | IC50(nM) = 27.0 |
| 77 | P10275_QA1 | QA1 | DB01406 | 28417 | CHEMBL1479 | Danazol | agonist | |
| 78 | P10275_DB01420 | n/a | DB01420 | n/a | n/a | Testosterone propionate | agonist | Ki(nM) = 0.25 |
| 79 | P10275_DB01428 | n/a | DB01428 | n/a | n/a | Oxybenzone | antagonist | |
| 80 | P10275_DB01481 | n/a | DB01481 | n/a | n/a | 1-Testosterone | agonist | |
| 81 | P10275_DB01541 | n/a | DB01541 | n/a | n/a | Boldenone | agonist | |
| 82 | P10275_DB01564 | n/a | DB01564 | n/a | n/a | Calusterone | inhibitor | |
| 83 | P10275_DB01608 | n/a | DB01608 | n/a | n/a | Periciazine | n/a | |
| 84 | P10275_AND | AND | DB01708 | 5881 | CHEMBL90593 | Prasterone | agonist | |
| 85 | P10275_HYQ | HYQ | DB04709 | n/a | n/a | (3AALPHA,4ALPHA,7ALPHA,7AALPHA)- 3A,4,7,7A-TETRAHYDRO-2-(4-NITRO-1-NAPHTHALENYL)-4,7-ETHANO-1H-ISOINDOLE-1,3(2H)-DIONE | n/a | |
| 86 | P10275_DB05234 | n/a | DB05234 | n/a | n/a | LGD2941 | modulator | Ki(nM) = 1.5 EC50(nM) = 7.1 |
| 87 | P10275_DB06133 | n/a | DB06133 | n/a | n/a | Dimethylcurcumin | inhibitor | |
| 88 | P10275_DB06412 | n/a | DB06412 | n/a | n/a | Oxymetholone | agonist | |
| 89 | P10275_DB06710 | n/a | DB06710 | n/a | n/a | Methyltestosterone | agonist | |
| 90 | P10275_DB06713 | n/a | DB06713 | n/a | n/a | Norelgestromin | partial agonist | |
| 91 | P10275_DB06718 | n/a | DB06718 | n/a | n/a | Stanozolol | agonist | |
| 92 | P10275_8NH | 8NH | DB07286 | 9882972 | CHEMBL229264 | BMS-564929 | inhibitor | |
| 93 | P10275_LG7 | LG7 | DB08087 | 9944398 | CHEMBL425646 | 4-[(7R,7AS)-7-HYDROXY-1,3-DIOXOTETRAHYDRO-1H-PYRROLO[1,2-C]IMIDAZOL-2(3H)-YL]-1-NAPHTHONITRILE | n/a | |
| 94 | P10275_LGB | LGB | DB08088 | n/a | CHEMBL484726 | 2-chloro-4-{[(1R,3Z,7S,7aS)-7-hydroxy-1-(trifluoromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-ylidene]amino}-3-methylbenzonitrile | n/a | Ki(nM) = 0.3 EC50(nM) = 0.2 |
| 95 | P10275_TCL | TCL | DB08604 | 5564 | CHEMBL849 | Triclosan | n/a | |
| 96 | P10275_DB08804 | n/a | DB08804 | n/a | n/a | Nandrolone decanoate | agonist | |
| 97 | P10275_DB08867 | n/a | DB08867 | n/a | n/a | Ulipristal | n/a | |
| 98 | P10275_DB08899 | n/a | DB08899 | n/a | n/a | Enzalutamide | inhibitor | Ki(nM) = 17.0 IC50(nM) = 14.0 Kd(nM) = 6520.0 EC50(nM) = 49.0 |
| 99 | P10275_EOL | EOL | DB09086 | 3314 | CHEMBL42710 | Eugenol | antagonist | IC50(nM) = 19000.0 |
| 100 | P10275_DB09123 | n/a | DB09123 | n/a | n/a | Dienogest | antagonist | |
| 101 | P10275_DB09371 | n/a | DB09371 | n/a | n/a | Norethynodrel | n/a | |
| 102 | P10275_DB09389 | n/a | DB09389 | n/a | n/a | Norgestrel | agonist | |
| 103 | P10275_DB11064 | n/a | DB11064 | n/a | n/a | Homosalate | antagonist | |
| 104 | P10275_DB11219 | n/a | DB11219 | n/a | n/a | Enzacamene | antagonist | |
| 105 | P10275_DB11425 | n/a | DB11425 | n/a | n/a | Luprostiol | inhibitor | |
| 106 | P10275_DB11429 | n/a | DB11429 | n/a | n/a | Mibolerone | agonist | |
| 107 | P10275_DB11447 | n/a | DB11447 | n/a | n/a | Phenothiazine | n/a | |
| 108 | P10275_DB11619 | n/a | DB11619 | n/a | n/a | Gestrinone | antagonist | |
| 109 | P10275_DB11901 | n/a | DB11901 | n/a | n/a | Apalutamide | antagonist | |
| 110 | P10275_DB12499 | n/a | DB12499 | n/a | n/a | Clascoterone | antagonist | |
| 111 | P10275_DB12941 | n/a | DB12941 | n/a | n/a | Darolutamide | antagonist | |
| 112 | P10275_7OU | 7OU | DB13155 | 5281417 | CHEMBL482581 | Esculin | agonist | |
| 113 | P10275_DB13934 | n/a | DB13934 | n/a | n/a | Ligandrol | antagonist | |
| 114 | P10275_DB13943 | n/a | DB13943 | n/a | n/a | Testosterone cypionate | agonist | |
| 115 | P10275_DB13944 | n/a | DB13944 | n/a | n/a | Testosterone enanthate | agonist | |
| 116 | P10275_DB13946 | n/a | DB13946 | n/a | n/a | Testosterone undecanoate | agonist | |
| 117 | P10275_DB13951 | n/a | DB13951 | n/a | n/a | Stanolone acetate | n/a | |
| 118 | P10275_DB14583 | n/a | DB14583 | n/a | n/a | Segesterone acetate | agonist | |
| 119 | P10275_DB14639 | n/a | DB14639 | n/a | n/a | Boldenone undecylenate | n/a | |
| 120 | P10275_DB15488 | n/a | DB15488 | n/a | n/a | Echinacoside | agonist | |
| 121 | P10275_DB15647 | n/a | DB15647 | n/a | n/a | Ketodarolutamide | antagonist |