Gene name: RARA
Protein name: Retinoic acid receptor
List of molecules and drugs that interact with protein P10276
# | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
---|---|---|---|---|---|---|---|---|
1 | P10276_5Z6 | 5Z6 | n/a | 6184667 | CHEMBL285480 | 4-[(E)-3-(3,5-ditert-butylphenyl)-3-oxidanylidene-prop-1-enyl]benzoic acid | n/a | |
2 | P10276_6Q7 | 6Q7 | n/a | 121225443 | CHEMBL3815166 | 4-{5-(3-tert-butylphenyl)-1-[4-(methylsulfonyl)phenyl]-1H-pyrazol-3-yl}benzoic acid | n/a | |
3 | P10276_BMS | BMS | n/a | 1711 | n/a | 4-[(4,4-DIMETHYL-1,2,3,4-TETRAHYDRO-[1,2']BINAPTHALENYL-7-CARBONYL)-AMINO]-BENZOIC ACID | n/a | |
4 | P10276_EQN | EQN | n/a | 2126 | CHEMBL69367 | 4-{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino}benzoic acid | n/a | |
5 | P10276_EQO | EQO | n/a | 9909190 | CHEMBL472172 | 4-{(E)-2-[5,5-dimethyl-8-(phenylethynyl)-5,6-dihydronaphthalen-2-yl]ethenyl}benzoic acid | n/a | |
6 | P10276_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
7 | P10276_LUF | LUF | n/a | n/a | n/a | (5S)-4-[(3E,7E)-4,8-dimethyl-10-(2,6,6-trimethylcyclohex-1-en-1-yl)deca-3,7-dien-1-yl]-5-hydroxyfuran-2(5H)-one | n/a | |
8 | P10276_REA | REA | DB00755 | 444795 | CHEMBL38 | RETINOIC ACID | agonist | |
9 | P10276_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
10 | P10276_DB00210 | n/a | DB00210 | n/a | n/a | Adapalene | n/a | Ki(nM) = 1100.0 EC50(nM) = 22.0 |
11 | P10276_DB00459 | n/a | DB00459 | n/a | n/a | Acitretin | agonist | |
12 | P10276_9CR | 9CR | DB00523 | 449171 | CHEMBL705 | Alitretinoin | agonist | Ki(nM) = 22.0 IC50(nM) = 7.0 Kd(nM) = 0.3 EC50(nM) = 1.0 |
13 | P10276_DB00799 | n/a | DB00799 | n/a | n/a | Tazarotene | agonist | EC50(nM) = 63.0 |
14 | P10276_DB00926 | n/a | DB00926 | n/a | n/a | Etretinate | agonist | |
15 | P10276_DB00982 | n/a | DB00982 | n/a | n/a | Isotretinoin | agonist | |
16 | P10276_A80 | A80 | DB04942 | 108143 | CHEMBL25202 | Tamibarotene | agonist | Ki(nM) = 6.5 IC50(nM) = 78.0 EC50(nM) = 45.0 |
17 | P10276_ARL | ARL | DB05785 | 5287705 | CHEMBL89241 | LGD-1550 | n/a | |
18 | P10276_DB12808 | n/a | DB12808 | n/a | n/a | Trifarotene | agonist |