Gene name: CYP2D6
Protein name: Cytochrome P450 2D6
List of molecules and drugs that interact with protein P10635
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P10635_2CV | 2CV | n/a | 49835947 | n/a | HEGA-10 | n/a | |
| 2 | P10635_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 3 | P10635_AJN | AJN | DB15949 | 441975 | CHEMBL123325 | Ajmalicine | n/a | |
| 4 | P10635_CPS | CPS | n/a | 107670 | CHEMBL450950 | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE | n/a | |
| 5 | P10635_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 6 | P10635_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 7 | P10635_HEM | HEM | DB18267 | n/a | n/a | PROTOPORPHYRIN IX CONTAINING FE | n/a | |
| 8 | P10635_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 9 | P10635_NI | NI | n/a | 934 | n/a | NICKEL (II) ION | n/a | |
| 10 | P10635_P6M | P6M | n/a | 123132915 | CHEMBL4088234 | (4S,6R)-4-[2,4-difluoro-5-({[1-(trifluoromethyl)cyclopropyl]amino}methyl)phenyl]-4,6-dimethyl-5,6-dihydro-4H-1,3-thiazin-2-amine | n/a | |
| 11 | P10635_P6U | P6U | n/a | 123132907 | CHEMBL4098403 | (4S)-4-[2,4-difluoro-5-({[1-(trifluoromethyl)cyclopropyl]amino}methyl)phenyl]-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine | n/a | |
| 12 | P10635_PN0 | PN0 | DB05100 | 466151 | CHEMBL75094 | Prinomastat | n/a | |
| 13 | P10635_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 14 | P10635_QDN | QDN | DB00908 | 441074 | CHEMBL1294 | Quinidine | n/a | Ki(nM) = 9.8 IC50(nM) = 2.0 |
| 15 | P10635_QI9 | QI9 | DB00468 | 3034034 | CHEMBL170 | Quinine | n/a | Ki(nM) = 4600.0 IC50(nM) = 10.0 |
| 16 | P10635_RTZ | RTZ | n/a | 6604030 | CHEMBL1357558 | 10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine | n/a | |
| 17 | P10635_SI5 | SI5 | n/a | 72547320 | CHEMBL3422238 | (4aR,6R,8aS)-8a-(2,4-difluorophenyl)-6-(1-methyl-1H-pyrazol-4-yl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine | n/a | |
| 18 | P10635_SI6 | SI6 | n/a | 91757962 | CHEMBL3422239 | (4aR,6R,8aS)-8a-(2,4-difluorophenyl)-6-(1H-pyrazol-4-yl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine | n/a | |
| 19 | P10635_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 20 | P10635_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 21 | P10635_P0T | P0T | DB09061 | 644019 | CHEMBL190461 | Cannabidiol | n/a | |
| 22 | P10635_DB11994 | n/a | DB11994 | n/a | n/a | Diacerein | inhibitor | |
| 23 | P10635_DB14011 | n/a | DB14011 | n/a | n/a | Nabiximols | substrate |