Gene name: THRA
Protein name: Thyroid hormone receptor
List of molecules and drugs that interact with protein P10827
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P10827_IH5 | IH5 | DB03176 | 9863447 | CHEMBL41036 | {3,5-DICHLORO-4-[4-HYDROXY-3-(PROPAN-2-YL)PHENOXY]PHENYL}ACETIC ACID | n/a | Ki(nM) = 7.18 IC50(nM) = 25.0 EC50(nM) = 1.7 |
| 2 | P10827_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 3 | P10827_T3 | T3 | DB00279 | 5920;7048703; | CHEMBL1544 | 3,5,3'TRIIODOTHYRONINE | agonist | Ki(nM) = 0.22 IC50(nM) = 0.24 Kd(nM) = 0.058 EC50(nM) = 0.41 |
| 4 | P10827_T44 | T44 | DB00451 | 5819;25201348; | CHEMBL1624 | 3,5,3',5'-TETRAIODO-L-THYRONINE | agonist | EC50(nM) = 19.0 |
| 5 | P10827_DB00509 | n/a | DB00509 | n/a | n/a | Dextrothyroxine | agonist | |
| 6 | P10827_DB01583 | n/a | DB01583 | n/a | n/a | Liotrix | agonist | |
| 7 | P10827_DB04855 | n/a | DB04855 | n/a | n/a | Dronedarone | inhibitor | |
| 8 | P10827_64L | 64L | DB05035 | 10299876 | CHEMBL2035874 | Eprotirome | n/a |