Gene name: PNMT
Protein name: Phenylethanolamine N-methyltransferase (PNMTase)
List of molecules and drugs that interact with protein P11086
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P11086_172 | 172 | DB03729 | 162636 | CHEMBL126589 | 2-AMINO-5-HYDROXY-BENZIMIDAZOLE | n/a | |
| 2 | P11086_1SQ | 1SQ | n/a | 73742 | CHEMBL62083 | ISOQUINOLIN-1-AMINE | n/a | |
| 3 | P11086_2D5 | 2D5 | n/a | 78673837 | n/a | 5'-S-(3-{[(3R)-1,2,3,4-tetrahydroisoquinolin-3-ylcarbonyl]amino}propyl)-5'-thioadenosine | n/a | |
| 4 | P11086_ADE | ADE | DB00173 | 190 | CHEMBL226345 | ADENINE | n/a | |
| 5 | P11086_AX7 | AX7 | n/a | 13624 | CHEMBL305513 | 1H-benzimidazol-2-amine | n/a | |
| 6 | P11086_CD | CD | n/a | 31193 | n/a | CADMIUM ION | n/a | |
| 7 | P11086_CTL | CTL | DB07597 | 6420129 | CHEMBL46085 | CIS-(1R,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL | n/a | |
| 8 | P11086_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 9 | P11086_ES0 | ES0 | n/a | 22475415 | n/a | 2-amino-1H-benzimidazol-7-ol | n/a | |
| 10 | P11086_ES1 | ES1 | n/a | 69141;5280925; | CHEMBL1232567 | quinolin-4-ol | n/a | |
| 11 | P11086_ES2 | ES2 | n/a | 736344 | CHEMBL1232568 | 6-chloro-1,3-dihydro-2H-indol-2-one | n/a | |
| 12 | P11086_ES3 | ES3 | n/a | 96125 | CHEMBL1232569 | 4-bromo-1H-imidazole | n/a | |
| 13 | P11086_ES4 | ES4 | n/a | 6886;5359277; | CHEMBL140037 | 6-chloro-9H-purine | n/a | |
| 14 | P11086_ES5 | ES5 | n/a | 11373 | CHEMBL99408 | quinolin-6-amine | n/a | |
| 15 | P11086_ES6 | ES6 | n/a | 69114 | CHEMBL53297 | 2-oxo-1,2-dihydropyridine-3-carboxylic acid | n/a | |
| 16 | P11086_ES7 | ES7 | n/a | 74187 | CHEMBL1232570 | 1-methyl-1H-benzimidazol-2-amine | n/a | |
| 17 | P11086_ES9 | ES9 | n/a | 78599 | CHEMBL69098 | 5-chloro-1H-benzimidazole | n/a | |
| 18 | P11086_ET2 | ET2 | n/a | 19017761 | n/a | 6-fluoro-1H-benzimidazol-2-amine | n/a | |
| 19 | P11086_F21 | F21 | DB07739 | 11485425 | CHEMBL177749 | (3R)-3-(FLUOROMETHYL)-7-(THIOMORPHOLIN-4-YLSULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE | n/a | Ki(nM) = 610.0 |
| 20 | P11086_F83 | F83 | DB07747 | 9549217 | n/a | (3R)-N-(4-CHLOROPHENYL)-3-(HYDROXYMETHYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE | n/a | |
| 21 | P11086_FAN | FAN | n/a | 7671 | CHEMBL1232659 | FORMANILIDE | n/a | |
| 22 | P11086_FTS | FTS | DB07798 | 11349402 | CHEMBL177101 | (3R)-3-(FLUOROMETHYL)-N-(3,3,3-TRIFLUOROPROPYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE | n/a | Ki(nM) = 99.0 |
| 23 | P11086_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 24 | P11086_HNT | HNT | DB07906 | 10822243 | CHEMBL293700 | [(3R)-7-NITRO-1,2,3,4-TETRAHYDROISOQUINOLIN-3-YL]METHANOL | n/a | |
| 25 | P11086_IDI | IDI | DB03824 | 5288606 | CHEMBL26828 | 7-IODO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE | n/a | Ki(nM) = 40.0 |
| 26 | P11086_IMD | IMD | DB03366 | 444234;4434133;21983501; | n/a | IMIDAZOLE | n/a | |
| 27 | P11086_JIL | JIL | n/a | 77232199 | n/a | 9-{5-S-[2-({[(3S)-7-nitro-1,2,3,4-tetrahydroisoquinolin-3-yl]methyl}amino)ethyl]-5-thio-alpha-L-lyxofuranosyl}-9H-purin-6-amine | n/a | |
| 28 | P11086_K | K | n/a | 813 | CHEMBL1233793 | POTASSIUM ION | n/a | |
| 29 | P11086_KNX | KNX | n/a | 166607339 | n/a | 5'-([(3S)-3-amino-3-carboxypropyl]{4-[(4R)-7,8-dichloro-1,2,3,4-tetrahydroisoquinolin-4-yl]butyl}amino)-5'-deoxyadenosine | n/a | |
| 30 | P11086_LNR | LNR | DB00368 | 439260 | CHEMBL1437 | L-NOREPINEPHRINE | n/a | |
| 31 | P11086_LT2 | LT2 | n/a | 49867257 | n/a | (3S)-3-hydroxy-2,3-dihydro-1H-indole-5,6-dione | n/a | |
| 32 | P11086_LT3 | LT3 | DB08128 | 44176358 | n/a | (1S,4R,9S)-5-(trifluoromethyl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-9-amine | n/a | |
| 33 | P11086_LT5 | LT5 | DB08129 | 36688409 | n/a | (1R)-2-amino-1-[3-(trifluoromethyl)phenyl]ethanol | n/a | |
| 34 | P11086_LY1 | LY1 | DB04273 | 121938 | CHEMBL38681 | 8,9-DICHLORO-2,3,4,5-TETRAHYDRO-1H-BENZO[C]AZEPINE | n/a | Ki(nM) = 10.0 |
| 35 | P11086_OTR | OTR | n/a | 440266 | CHEMBL1160703 | 4-(2R-AMINO-1-HYDROXYETHYL)PHENOL | n/a | |
| 36 | P11086_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 37 | P11086_RCO | RCO | DB11085 | 5054 | CHEMBL24147 | RESORCINOL | n/a | |
| 38 | P11086_SAH | SAH | DB01752 | 439155;25246222; | CHEMBL418052 | S-ADENOSYL-L-HOMOCYSTEINE | n/a | |
| 39 | P11086_SAM | SAM | DB00118 | n/a | CHEMBL1235831 | S-ADENOSYLMETHIONINE | n/a | |
| 40 | P11086_SKA | SKA | DB08550 | 123920 | CHEMBL287837 | 7,8-DICHLORO-1,2,3,4-TETRAHYDROISOQUINOLINE | n/a | Ki(nM) = 1.55 IC50(nM) = 3.0 |
| 41 | P11086_SKF | SKF | DB03468 | 5226 | CHEMBL26717 | 1,2,3,4-TETRAHYDRO-ISOQUINOLINE-7-SULFONIC ACID AMIDE | n/a | Ki(nM) = 120.0 |
| 42 | P11086_TMJ | TMJ | DB08631 | 12606920 | CHEMBL286497 | N-(4-CHLOROPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE | n/a | Ki(nM) = 210.0 |
| 43 | P11086_TRS | TRS | DB03754 | 3777159;88088752;152743085; | n/a | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | n/a | |
| 44 | P11086_TTL | TTL | DB08654 | 6420130 | CHEMBL46439 | TRANS-(1S,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL | n/a | |
| 45 | P11086_U87 | U87 | n/a | 154572002 | n/a | 5'-([(3S)-3-amino-3-carboxypropyl]{3-[(4R)-7,8-dichloro-1,2,3,4-tetrahydroisoquinolin-4-yl]propyl}amino)-5'-deoxyadenosine | n/a | |
| 46 | P11086_VGD | VGD | n/a | 21527 | CHEMBL269158 | 6-chloro-1H-benzimidazol-2-amine | n/a |