Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
P11229 ACM1_HUMAN
Gene name: CHRM1
Protein name: Muscarinic acetylcholine receptor

List of molecules and drugs that interact with protein P11229

# DrugDomain Data PBD ligand DrugBank Accession PubChem ChEMBL Name Drug action Affinity data
1 P11229_0HK 0HK DB01409 n/a CHEMBL1900528 (1R,2R,4S,5S,7S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane antagonist
2 P11229_ACM ACM DB02736 178 CHEMBL16081 ACETAMIDE n/a
3 P11229_EDO EDO n/a 174 CHEMBL457299 1,2-ETHANEDIOL n/a
4 P11229_EPE EPE DB16872 23830;23831;3275884; CHEMBL1232545 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID n/a
5 P11229_GOL GOL DB09462 753 CHEMBL692 GLYCEROL n/a
6 P11229_IXO IXO n/a 10104167 CHEMBL3121473 4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium n/a
7 P11229_OIN OIN DB00572 n/a CHEMBL1234973 (1R,5S)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL (2R)-3-HYDROXY-2-PHENYLPROPANOATE antagonist Ki(nM) = 0.3
8 P11229_OLA OLA n/a 445639 CHEMBL8659 OLEIC ACID n/a
9 P11229_OLC OLC n/a 11451146 n/a (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate n/a
10 P11229_PGE PGE DB02327 8172 CHEMBL1235259 TRIETHYLENE GLYCOL n/a
11 P11229_PO4 PO4 DB14523 1061 n/a PHOSPHATE ION n/a
12 P11229_QJT QJT n/a 10236758 CHEMBL3354065 1-[3-(4-butylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one n/a
13 P11229_QK2 QK2 n/a 16038386 CHEMBL5095238 7-fluoranyl-5-methyl-3-[1-(oxan-4-yl)piperidin-4-yl]-1~{H}-benzimidazol-2-one n/a
14 P11229_QK8 QK8 n/a 71528459 CHEMBL5314959 ethyl (4~{S})-4-[4-[(1-methylcyclobutyl)carbamoyl]piperidin-1-yl]azepane-1-carboxylate n/a
15 P11229_Y01 Y01 n/a 65082 n/a CHOLESTEROL HEMISUCCINATE n/a
16 P11229_DB00185 n/a DB00185 n/a n/a Cevimeline agonist
17 P11229_DB00193 n/a DB00193 n/a n/a Tramadol antagonist
18 P11229_DB00209 n/a DB00209 n/a n/a Trospium antagonist
19 P11229_DB00219 n/a DB00219 n/a n/a Oxyphenonium antagonist
20 P11229_CXQ CXQ DB00245 n/a CHEMBL1201203 Benzatropine antagonist
21 P11229_DB00246 n/a DB00246 n/a n/a Ziprasidone antagonist Ki(nM) = 300.0
22 P11229_DB00280 n/a DB00280 n/a n/a Disopyramide antagonist
23 P11229_DB00332 n/a DB00332 n/a n/a Ipratropium antagonist
24 P11229_DB00334 n/a DB00334 n/a n/a Olanzapine antagonist Ki(nM) = 2.1
EC50(nM) = 100000.0
25 P11229_DB00342 n/a DB00342 n/a n/a Terfenadine binder IC50(nM) = 2900.0
26 P11229_DB00354 n/a DB00354 n/a n/a Buclizine antagonist
27 P11229_DB00363 n/a DB00363 n/a n/a Clozapine partial agonist Ki(nM) = 0.98
IC50(nM) = 9.4
EC50(nM) = 10000.0
28 P11229_DB00376 n/a DB00376 n/a n/a Trihexyphenidyl antagonist Ki(nM) = 0.37
IC50(nM) = 1.3
29 P11229_DB00383 n/a DB00383 n/a n/a Oxyphencyclimine antagonist
30 P11229_DB00387 n/a DB00387 n/a n/a Procyclidine antagonist Ki(nM) = 4.6
31 P11229_DB00392 n/a DB00392 n/a n/a Profenamine antagonist
32 P11229_DB00408 n/a DB00408 n/a n/a Loxapine binder Ki(nM) = 63.9
IC50(nM) = 5500.0
33 P11229_CCE CCE DB00411 2551 CHEMBL965 Carbamoylcholine agonist Ki(nM) = 29.0
IC50(nM) = 457.0
EC50(nM) = 250.0
34 P11229_P2Z P2Z DB00420 4926 CHEMBL564 Promazine antagonist
35 P11229_HYO HYO DB00424 n/a CHEMBL1331216 Hyoscyamine antagonist
36 P11229_C7H C7H DB00434 2913 CHEMBL516 Cyproheptadine antagonist Ki(nM) = 12.0
37 P11229_IXX IXX DB00458 3696 CHEMBL11 Imipramine antagonist Ki(nM) = 42.0
38 P11229_DB00462 n/a DB00462 n/a n/a Methscopolamine bromide antagonist
39 P11229_Z80 Z80 DB00477 2726 CHEMBL71 Chlorpromazine antagonist Ki(nM) = 25.0
40 P11229_DB00483 n/a DB00483 n/a n/a Gallamine triethiodide n/a Ki(nM) = 8511.38
EC50(nM) = 170000.0
41 P11229_DB00496 n/a DB00496 n/a n/a Darifenacin antagonist Ki(nM) = 5.5
42 P11229_DB00505 n/a DB00505 n/a n/a Tridihexethyl antagonist
43 P11229_DB00508 n/a DB00508 n/a n/a Triflupromazine antagonist
44 P11229_DB00517 n/a DB00517 n/a n/a Anisotropine methylbromide antagonist
45 P11229_DB00543 n/a DB00543 n/a n/a Amoxapine antagonist
46 P11229_DB00572 n/a DB00572 n/a n/a Atropine antagonist Ki(nM) = 0.3
47 P11229_DB00622 n/a DB00622 n/a n/a Nicardipine antagonist
48 P11229_DB00670 n/a DB00670 n/a n/a Pirenzepine antagonist Ki(nM) = 2.82
IC50(nM) = 1.5
Kd(nM) = 20.0
49 P11229_DB00725 n/a DB00725 n/a n/a Homatropine methylbromide antagonist
50 P11229_DB00747 n/a DB00747 n/a n/a Scopolamine antagonist
51 P11229_DB00767 n/a DB00767 n/a n/a Benzquinamide antagonist
52 P11229_DB00771 n/a DB00771 n/a n/a Clidinium antagonist
53 P11229_DB00782 n/a DB00782 n/a n/a Propantheline antagonist
54 P11229_DB00804 n/a DB00804 n/a n/a Dicyclomine antagonist
55 P11229_DB00805 n/a DB00805 n/a n/a Minaprine agonist Ki(nM) = 17000.0
56 P11229_DB00809 n/a DB00809 n/a n/a Tropicamide antagonist
57 P11229_DB00810 n/a DB00810 n/a n/a Biperiden antagonist Ki(nM) = 0.48
58 P11229_DB00835 n/a DB00835 n/a n/a Brompheniramine antagonist
59 P11229_DB00875 n/a DB00875 n/a n/a Flupentixol antagonist
60 P11229_COC COC DB00907 446220 CHEMBL370805 Cocaine antagonist
61 P11229_DB00934 n/a DB00934 n/a n/a Maprotiline antagonist
62 P11229_DB00940 n/a DB00940 n/a n/a Methantheline antagonist
63 P11229_DB00942 n/a DB00942 n/a n/a Cycrimine antagonist
64 P11229_DB00979 n/a DB00979 n/a n/a Cyclopentolate antagonist
65 P11229_DB00986 n/a DB00986 n/a n/a Glycopyrronium antagonist IC50(nM) = 0.126
66 P11229_DB01019 n/a DB01019 n/a n/a Bethanechol agonist Ki(nM) = 190.0
67 P11229_DB01036 n/a DB01036 n/a n/a Tolterodine antagonist Ki(nM) = 1.4
68 P11229_DB01062 n/a DB01062 n/a n/a Oxybutynin antagonist Ki(nM) = 1.0
69 P11229_DB01069 n/a DB01069 n/a n/a Promethazine antagonist
70 P11229_9PL 9PL DB01085 5910 CHEMBL550 Pilocarpine agonist Ki(nM) = 12.0
Kd(nM) = 2692.0
EC50(nM) = 18.0
71 P11229_DB01142 no_lig_id DB01142 n/a n/a Doxepin antagonist
72 P11229_DB01148 n/a DB01148 n/a n/a Flavoxate antagonist
73 P11229_DSM DSM DB01151 2995 CHEMBL72 Desipramine antagonist Ki(nM) = 110.0
74 P11229_68P 68P DB01175 146570 CHEMBL1508 Escitalopram inhibitor
75 P11229_DB01224 n/a DB01224 n/a n/a Quetiapine antagonist Ki(nM) = 56.0
EC50(nM) = 10000.0
76 P11229_DB01231 n/a DB01231 n/a n/a Diphenidol antagonist
77 P11229_DB01233 n/a DB01233 n/a n/a Metoclopramide agonist
78 P11229_9SC 9SC DB01238 60795 CHEMBL1112 Aripiprazole ligand Ki(nM) = 6780.0
79 P11229_DB01239 n/a DB01239 n/a n/a Chlorprothixene antagonist
80 P11229_DB01403 n/a DB01403 n/a n/a Methotrimeprazine antagonist
81 P11229_DB01591 n/a DB01591 n/a n/a Solifenacin antagonist Ki(nM) = 51.0
IC50(nM) = 63.5
82 P11229_DB01618 n/a DB01618 n/a n/a Molindone other/unknown
83 P11229_STU STU DB02010 44259 CHEMBL388978 Staurosporine n/a
84 P11229_ACH ACH DB03128 187 CHEMBL667 Acetylcholine n/a Ki(nM) = 3.4
IC50(nM) = 135.0
Kd(nM) = 17378.0
EC50(nM) = 1.1
85 P11229_DB04365 n/a DB04365 n/a n/a Arecoline inhibitor Ki(nM) = 4.1
IC50(nM) = 115.0
EC50(nM) = 3200.0
86 P11229_DB04843 n/a DB04843 n/a n/a Mepenzolate antagonist
87 P11229_DB05152 n/a DB05152 n/a n/a NGX267 agonist
88 P11229_DB05766 n/a DB05766 n/a n/a Norclozapine modulator
89 P11229_DB06153 n/a DB06153 n/a n/a Pizotifen antagonist
90 P11229_DB06702 n/a DB06702 n/a n/a Fesoterodine antagonist
91 P11229_DB06709 n/a DB06709 n/a n/a Methacholine agonist Ki(nM) = 23.0
92 P11229_DB06787 n/a DB06787 n/a n/a Hexocyclium antagonist
93 P11229_DB08897 n/a DB08897 n/a n/a Aclidinium antagonist Ki(nM) = 0.08
IC50(nM) = 0.1
94 P11229_DB09076 n/a DB09076 n/a n/a Umeclidinium antagonist Ki(nM) = 0.16
95 P11229_DB09089 n/a DB09089 n/a n/a Trimebutine antagonist
96 P11229_DB09167 n/a DB09167 n/a n/a Dosulepin antagonist
97 P11229_DB09185 n/a DB09185 n/a n/a Viloxazine antagonist
98 P11229_DB09262 n/a DB09262 n/a n/a Imidafenacin antagonist
99 P11229_DB11156 n/a DB11156 n/a n/a Pyrantel antagonist
100 P11229_DB11181 n/a DB11181 n/a n/a Homatropine antagonist
101 P11229_DB11235 n/a DB11235 n/a n/a Thonzylamine antagonist
102 P11229_DB12278 n/a DB12278 n/a n/a Propiverine antagonist
103 P11229_DB13581 n/a DB13581 n/a n/a Rociverine antagonist
104 P11229_DB14185 n/a DB14185 n/a n/a Aripiprazole lauroxil n/a