P11388 TOP2A_HUMAN
Gene name: TOP2A
Protein name: DNA topoisomerase 2-alpha

List of molecules and drugs that interact with protein P11388

#	DrugDomain Data	PBD ligand	DrugBank Accession	PubChem	ChEMBL	Name	Drug action	Affinity data
1	P11388_ADP	ADP	DB16833	6022	CHEMBL14830	ADENOSINE-5'-DIPHOSPHATE	n/a
2	P11388_ANP	ANP	n/a	33113	CHEMBL1230989	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	n/a
3	P11388_EVP	EVP	DB00773	36462	CHEMBL44657	(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside	inhibitor	IC50(nM) = 4700.0 EC50(nM) = 810.0
4	P11388_GOL	GOL	DB09462	753	CHEMBL692	GLYCEROL	n/a
5	P11388_MG	MG	n/a	888	n/a	MAGNESIUM ION	n/a
6	P11388_SO4	SO4	DB14546	1117	n/a	SULFATE ION	n/a
7	P11388_MFX	MFX	DB00218	152946;40467042;	CHEMBL32	Moxifloxacin	inhibitor
8	P11388_ASW	ASW	DB00276	2179	CHEMBL43	Amsacrine	inhibitor	IC50(nM) = 1000.0 EC50(nM) = 720.0
9	P11388_DB00380	n/a	DB00380	n/a	n/a	Dexrazoxane	inhibitor
10	P11388_DB00385	n/a	DB00385	n/a	n/a	Valrubicin	inhibitor
11	P11388_9TP	9TP	DB00444	452548	CHEMBL452231	Teniposide	inhibitor
12	P11388_DB00445	n/a	DB00445	n/a	n/a	Epirubicin	inhibitor	IC50(nM) = 3.0
13	P11388_DB00467	n/a	DB00467	n/a	n/a	Enoxacin	inhibitor
14	P11388_DB00487	n/a	DB00487	n/a	n/a	Pefloxacin	inhibitor
15	P11388_CPF	CPF	DB00537	2764;4011971;	CHEMBL8	Ciprofloxacin	inhibitor	IC50(nM) = 100000.0 EC50(nM) = 30.0
16	P11388_TR6	TR6	DB00685	n/a	CHEMBL428	Trovafloxacin	inhibitor
17	P11388_DM1	DM1	DB00694	30323	CHEMBL178	Daunorubicin	inhibitor	IC50(nM) = 10.0
18	P11388_DB00978	n/a	DB00978	n/a	n/a	Lomefloxacin	inhibitor
19	P11388_DM2	DM2	DB00997	31703	CHEMBL53463	Doxorubicin	inhibitor	IC50(nM) = 4.9
20	P11388_DB01059	n/a	DB01059	n/a	n/a	Norfloxacin	inhibitor
21	P11388_DB01165	n/a	DB01165	n/a	n/a	Ofloxacin	inhibitor
22	P11388_DM5	DM5	DB01177	42890	CHEMBL1117	Idarubicin	inhibitor	IC50(nM) = 2.6
23	P11388_POD	POD	DB01179	10607	CHEMBL61	Podofilox	inhibitor
24	P11388_MIX	MIX	DB01204	4212	CHEMBL58	Mitoxantrone	inhibitor	IC50(nM) = 5300.0
25	P11388_DB01208	n/a	DB01208	n/a	n/a	Sparfloxacin	inhibitor
26	P11388_GEN	GEN	DB01645	5280961	CHEMBL44	Genistein	n/a	IC50(nM) = 111000.0
27	P11388_DB04576	n/a	DB04576	n/a	n/a	Fleroxacin	inhibitor
28	P11388_DB04967	n/a	DB04967	n/a	n/a	Lucanthone	inhibitor
29	P11388_DB04975	n/a	DB04975	n/a	n/a	Banoxantrone	modulator
30	P11388_DB05022	n/a	DB05022	n/a	n/a	Amonafide	n/a
31	P11388_DB05129	n/a	DB05129	n/a	n/a	Elsamitrucin	modulator
32	P11388_DB05706	n/a	DB05706	n/a	n/a	13-deoxydoxorubicin	n/a
33	P11388_DB06013	n/a	DB06013	n/a	n/a	Aldoxorubicin	inhibitor
34	P11388_DB06263	n/a	DB06263	n/a	n/a	Amrubicin	n/a
35	P11388_DB06362	n/a	DB06362	n/a	n/a	Becatecarin	n/a
36	P11388_DB06420	n/a	DB06420	n/a	n/a	Annamycin	other/unknown
37	P11388_DB06421	n/a	DB06421	n/a	n/a	Declopramide	n/a
38	P11388_DB09047	n/a	DB09047	n/a	n/a	Finafloxacin	inhibitor