Gene name: CYP19A1
Protein name: Aromatase (EC 1.14.14.14)
List of molecules and drugs that interact with protein P11511
# | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
---|---|---|---|---|---|---|---|---|
1 | P11511_0XJ | 0XJ | n/a | 53482563 | CHEMBL2179110 | (6alpha,8alpha)-6-(pent-2-yn-1-yloxy)androsta-1,4-diene-3,17-dione | n/a | |
2 | P11511_1PE | 1PE | n/a | 62551 | CHEMBL1229766 | PENTAETHYLENE GLYCOL | n/a | |
3 | P11511_ASD | ASD | DB01536 | 6128 | CHEMBL274826 | 4-ANDROSTENE-3-17-DIONE | inhibitor | |
4 | P11511_EXM | EXM | DB00990 | 60198 | CHEMBL1200374 | (8alpha,10alpha,13alpha)-6-methylideneandrosta-1,4-diene-3,17-dione | inhibitor | Ki(nM) = 0.95 IC50(nM) = 15.0 |
5 | P11511_G29 | G29 | n/a | 60156307 | CHEMBL2179109 | (6alpha,8alpha)-6-(but-2-yn-1-yloxy)androsta-1,4-diene-3,17-dione | n/a | |
6 | P11511_HEM | HEM | DB18267 | n/a | n/a | PROTOPORPHYRIN IX CONTAINING FE | n/a | |
7 | P11511_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
8 | P11511_TES | TES | DB00624 | 6013 | CHEMBL386630 | TESTOSTERONE | n/a | Ki(nM) = 600.0 |
9 | P11511_NCT | NCT | DB00184 | 89594 | CHEMBL3 | Nicotine | inhibitor | |
10 | P11511_DB00357 | n/a | DB00357 | n/a | n/a | Aminoglutethimide | inhibitor | Ki(nM) = 470.0 IC50(nM) = 5.2 |
11 | P11511_J3Z | J3Z | DB00655 | 5870 | CHEMBL1405 | Estrone | n/a | |
12 | P11511_DB00894 | n/a | DB00894 | n/a | n/a | Testolactone | inhibitor | Ki(nM) = 35000.0 |
13 | P11511_DB01006 | n/a | DB01006 | n/a | n/a | Letrozole | antagonist | Ki(nM) = 0.02 IC50(nM) = 0.7 |
14 | P11511_DB01217 | n/a | DB01217 | n/a | n/a | Anastrozole | inhibitor | Ki(nM) = 0.13 IC50(nM) = 1.5 |
15 | P11511_ESM | ESM | DB02342 | 66414 | CHEMBL299613 | 2-Methoxyestradiol | n/a | |
16 | P11511_NAR | NAR | DB03467 | 439246 | CHEMBL9352 | Naringenin | inhibitor | IC50(nM) = 2.9 |
17 | P11511_GPJ | GPJ | DB04539 | 5288464;59121227;59121230;152743071; | n/a | Glyphosate | n/a | |
18 | P11511_DB16236 | n/a | DB16236 | n/a | n/a | Mitapivat | inhibitor |