Gene name: CDK4
Protein name: Cyclin-dependent kinase 4
List of molecules and drugs that interact with protein P11802
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P11802_6ZV | 6ZV | DB12001 | 46220502 | CHEMBL3301610 | N-{5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-benzimidazol-6-yl]py rimidin-2-amine | inhibitor | |
| 2 | P11802_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 3 | P11802_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 4 | P11802_PVB | PVB | DB02733 | 448991 | CHEMBL23254 | Purvalanol | n/a | IC50(nM) = 10000.0 |
| 5 | P11802_CPB | CPB | DB03496 | 5287969 | CHEMBL428690 | Alvocidib | n/a | Ki(nM) = 40.0 IC50(nM) = 10.0 Kd(nM) = 3.3 |
| 6 | P11802_LQQ | LQQ | DB09073 | 5330286 | CHEMBL189963 | Palbociclib | inhibitor | Ki(nM) = 3.0 IC50(nM) = 2.0 |
| 7 | P11802_6ZZ | 6ZZ | DB11730 | 44631912 | CHEMBL3545110 | Ribociclib | antagonist | |
| 8 | P11802_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor | |
| 9 | P11802_DB15442 | n/a | DB15442 | n/a | n/a | Trilaciclib | inhibitor |