Gene name: RARG
Protein name: Retinoic acid receptor
List of molecules and drugs that interact with protein P13631
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P13631_156 | 156 | DB02466 | 445576 | CHEMBL95700 | 4-[3-OXO-3-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-PROPENYL]-BENZOIC ACID | n/a | Kd(nM) = 0.6 |
| 2 | P13631_184 | 184 | DB03466 | 445575 | CHEMBL81273 | 6-[HYDROXY-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTALEN-2-YL)-METHYL]-NAPHTALENE-2-CARBOXYLIC ACID | inhibitor | Kd(nM) = 75.0 |
| 3 | P13631_254 | 254 | DB02258 | 9887304 | n/a | 6-[HYDROXYIMINO-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTALEN-2-YL)-METHYL]-NAPHTALENE-2-CARBOXYLIC ACID | n/a | |
| 4 | P13631_564 | 564 | DB02741 | 2605 | CHEMBL309282 | 6-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTALENE-2-CARBONYL)-NAPHTALENE-2-CARBOXYLIC ACID | inhibitor | Kd(nM) = 3.0 |
| 5 | P13631_9CR | 9CR | DB00523 | 449171 | CHEMBL705 | (9cis)-retinoic acid | agonist | Ki(nM) = 1.0 IC50(nM) = 17.0 Kd(nM) = 0.8 EC50(nM) = 4.0 |
| 6 | P13631_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 7 | P13631_E9T | E9T | n/a | n/a | n/a | 6-[3-(1-adamantyl)-4-oxidanyl-phenyl]naphthalene-2-carboxylic acid | n/a | |
| 8 | P13631_LMU | LMU | DB03279 | 445456 | CHEMBL1234048 | DODECYL-ALPHA-D-MALTOSIDE | inhibitor | |
| 9 | P13631_PG4 | PG4 | n/a | 8200 | CHEMBL1235254 | TETRAETHYLENE GLYCOL | n/a | |
| 10 | P13631_DB00210 | n/a | DB00210 | n/a | n/a | Adapalene | agonist | Ki(nM) = 130.0 EC50(nM) = 3.1 |
| 11 | P13631_DB00459 | n/a | DB00459 | n/a | n/a | Acitretin | agonist | |
| 12 | P13631_REA | REA | DB00755 | 444795 | CHEMBL38 | Tretinoin | agonist | |
| 13 | P13631_DB00799 | n/a | DB00799 | n/a | n/a | Tazarotene | agonist | EC50(nM) = 40.0 |
| 14 | P13631_DB00926 | n/a | DB00926 | n/a | n/a | Etretinate | agonist | |
| 15 | P13631_DB00982 | n/a | DB00982 | n/a | n/a | Isotretinoin | agonist | |
| 16 | P13631_DB02258 | n/a | DB02258 | n/a | n/a | SR11254 | n/a | |
| 17 | P13631_DB05467 | n/a | DB05467 | n/a | n/a | Palovarotene | agonist | |
| 18 | P13631_ARL | ARL | DB05785 | 5287705 | CHEMBL89241 | LGD-1550 | n/a | |
| 19 | P13631_394 | 394 | DB07031 | 445455 | n/a | 3-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acid | agonist | |
| 20 | P13631_961 | 961 | DB07294 | 445460 | n/a | 3-fluoro-4-[2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8,-tetrahydro-naphtalen-2-yl)-acetylamino]-benzoic acid | n/a | Ki(nM) = 1.5 Kd(nM) = 528.0 |
| 21 | P13631_DB12808 | n/a | DB12808 | n/a | n/a | Trifarotene | agonist |