Gene name: MIF
Protein name: Macrophage migration inhibitory
List of molecules and drugs that interact with protein P14174
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P14174_0FI | 0FI | n/a | 12501;3032341; | n/a | N-phenylthioformamide | n/a | |
| 2 | P14174_0IN | 0IN | n/a | 44251515 | n/a | 7-(pyridin-3-ylmethyl)quinolin-8-ol | n/a | |
| 3 | P14174_1Q1 | 1Q1 | n/a | 136629343 | n/a | 1-[(5S)-3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]propan-2-one | n/a | |
| 4 | P14174_1Q2 | 1Q2 | n/a | n/a | n/a | (4R,6Z)-6-(3-fluoro-4-hydroxyphenyl)-4-hydroxy-6-iminohexan-2-one | n/a | |
| 5 | P14174_1X2 | 1X2 | n/a | 114757 | CHEMBL461242 | 6-isothiocyanatohexylbenzene | n/a | |
| 6 | P14174_1ZW | 1ZW | n/a | 53991228 | n/a | N-[(4-cyanophenyl)methyl]methanethioamide | n/a | |
| 7 | P14174_31E | 31E | n/a | 58279630 | n/a | (Z)-[(furan-2-ylmethyl)imino]methanethiol | n/a | |
| 8 | P14174_35J | 35J | n/a | 58279648 | n/a | N-(pyridin-3-ylmethyl)thioformamide | n/a | |
| 9 | P14174_3E1 | 3E1 | n/a | 130451 | n/a | N,N'-(6,6'-dihydroxybiphenyl-3,3'-diyl)diacetamide | n/a | |
| 10 | P14174_3TW | 3TW | n/a | 90684377 | CHEMBL3798149 | 4-{4-[6-(2-methoxyethoxy)quinolin-2-yl]-1H-1,2,3-triazol-1-yl}phenol | n/a | |
| 11 | P14174_3TX | 3TX | n/a | 90684376 | CHEMBL3953102 | 4-[4-(quinolin-2-yl)-1H-1,2,3-triazol-1-yl]phenol | n/a | |
| 12 | P14174_428 | 428 | n/a | 44820635 | n/a | 2-(1-methylethyl)imidazo[1,2-b]pyridazin-6-ol | n/a | |
| 13 | P14174_47X | 47X | n/a | 5284648 | CHEMBL13486 | 3-(3,4-dihydroxyphenyl)-7-hydroxy-4H-chromen-4-one | n/a | |
| 14 | P14174_4FQ | 4FQ | n/a | n/a | CHEMBL4785454 | 4-amino-5-hydroxy-6-[(E)-(3-{[3-(2-methylpropanoyl)pyrazolo[1,5-a]pyridin-2-yl]methyl}phenyl)diazenyl]naphthalene-1,3-disulfonic acid | n/a | |
| 15 | P14174_4MT | 4MT | n/a | 129932451 | n/a | N-[2-(4-hydroxyphenyl)ethyl]thioformamide | n/a | |
| 16 | P14174_65V | 65V | n/a | 91667576 | CHEMBL3917143 | 3-({2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]quinolin-5-yl}oxy)benzoic acid | n/a | |
| 17 | P14174_6B9 | 6B9 | n/a | 5288219;5496777; | n/a | 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-5-[(E)-(sulfanylmethylidene)amino]benzoic acid | n/a | |
| 18 | P14174_6DQ | 6DQ | n/a | 9834654 | n/a | 2-pyridin-3-yl-1,3-benzothiazin-4-one | n/a | |
| 19 | P14174_6H1 | 6H1 | n/a | 118988443 | n/a | 6-{[4-(trifluoromethyl)phenyl]methyl}-2H-1,3-benzodioxol-5-ol | n/a | |
| 20 | P14174_6H2 | 6H2 | n/a | 764266 | CHEMBL1527214 | 4-(imidazo[1,2-a]pyridin-2-yl)benzene-1,2-diol | n/a | |
| 21 | P14174_6UV | 6UV | n/a | 72440 | CHEMBL156 | (2~{R})-2-[[4-[[2,4-bis(azanyl)pteridin-6-yl]methyl-methyl-amino]phenyl]carbonylamino]pentanedioic acid | n/a | |
| 22 | P14174_88X | 88X | n/a | 44820636;135566514; | n/a | 5-ethyl-2-(phenylcarbonyl)imidazo[1,2-a]pyrimidin-7(1H)-one | n/a | |
| 23 | P14174_956 | 956 | n/a | 21081924 | n/a | 1-methyl-2-oxo-4-[4-(thiophen-2-ylcarbonyl)piperazin-1-yl]-1,2-dihydroquinoline-3-carbonitrile | n/a | |
| 24 | P14174_9AI | 9AI | n/a | 10898661 | n/a | N-prop-2-en-1-ylthioformamide | n/a | |
| 25 | P14174_9BE | 9BE | n/a | 12975216 | n/a | N-benzylthioformamide | n/a | |
| 26 | P14174_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 27 | P14174_AVL | AVL | DB05266 | 3671 | CHEMBL19449 | 2-methyl-1-[2-(propan-2-yl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one | n/a | Ki(nM) = 30900.0 Kd(nM) = 1400.0 |
| 28 | P14174_AVR | AVR | n/a | 45490005 | n/a | (2R)-2-amino-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one | n/a | |
| 29 | P14174_C9G | C9G | n/a | 122457241 | CHEMBL4169208 | 2-[1-(4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-7-methyl-1,7-naphthyridin-8(7H)-one | n/a | |
| 30 | P14174_C9J | C9J | n/a | 131953495 | CHEMBL4160035 | 2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-7-methyl-1,7-naphthyridin-8(7H)-one | n/a | |
| 31 | P14174_C9Y | C9Y | n/a | 137349074 | CHEMBL4170679 | {2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-8-oxo-1,7-naphthyridin-7(8H)-yl}acetic acid | n/a | |
| 32 | P14174_CIT | CIT | DB04272 | 311;19782904;88113319; | CHEMBL1261 | CITRIC ACID | n/a | |
| 33 | P14174_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 34 | P14174_DHC | DHC | DB01880 | 689043 | CHEMBL145 | CAFFEIC ACID | inhibitor | |
| 35 | P14174_DIO | DIO | DB03316 | 31275 | CHEMBL453716 | 1,4-DIETHYLENE DIOXIDE | n/a | |
| 36 | P14174_DMF | DMF | DB01844 | 6228 | CHEMBL268291 | DIMETHYLFORMAMIDE | n/a | |
| 37 | P14174_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 38 | P14174_EN1 | EN1 | n/a | 444783 | n/a | (2E)-2-hydroxy-3-(4-hydroxyphenyl)prop-2-enoic acid | n/a | |
| 39 | P14174_ENO | ENO | DB07718 | 979 | CHEMBL607712 | 3-(4-HYDROXY-PHENYL)PYRUVIC ACID | inhibitor | |
| 40 | P14174_EV7 | EV7 | n/a | 132473011 | n/a | 2-[(naphthalen-2-yl)oxy]-5-(1H-pyrazol-4-yl)benzoic acid | n/a | |
| 41 | P14174_EWD | EWD | n/a | 132473014 | n/a | 2-phenoxy-5-(1H-pyrazol-4-yl)benzoic acid | n/a | |
| 42 | P14174_EWG | EWG | n/a | 7174253 | CHEMBL4214963 | 3-(1H-pyrazol-4-yl)benzoic acid | n/a | |
| 43 | P14174_EWJ | EWJ | n/a | 132473015 | CHEMBL4218738 | 5-(3-fluoro-1H-pyrazol-4-yl)-2-[(naphthalen-2-yl)oxy]benzoic acid | n/a | |
| 44 | P14174_GBJ | GBJ | n/a | 124052 | CHEMBL480477 | 4-[(3R)-8,8-dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol | n/a | |
| 45 | P14174_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 46 | P14174_HBX | HBX | n/a | 240 | CHEMBL15972 | benzaldehyde | n/a | |
| 47 | P14174_HDI | HDI | DB07888 | 5288525 | CHEMBL211769 | 3-(4-HYDROXYPHENYL)-4,5-DIHYDRO-5-ISOXAZOLE-ACETIC ACID METHYL ESTER | n/a | IC50(nM) = 7000.0 |
| 48 | P14174_HWL | HWL | DB01148 | 3354 | CHEMBL1493 | Flavoxate | n/a | |
| 49 | P14174_HWO | HWO | n/a | 166607335 | n/a | (2R)-7-[(2R,3R,4R,5S,6S)-6-(hydroxymethyl)-3-[(2R,3R,4R,5R,6S)-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-4,5-bis(oxidanyl)oxan-2-yl]oxy-2-(4-methoxy-3-oxidanyl-phenyl)-5-oxidanyl-2,3-dihydrochromen-4-one | n/a | |
| 50 | P14174_HWR | HWR | n/a | 166607336 | n/a | (2S,3R,4R,5R,6R)-2-[(2S,3R,4S,5R,6S)-6-(hydroxymethyl)-2-[[(2R,4R)-2-(4-hydroxyphenyl)-4,5-bis(oxidanyl)-3,4-dihydro-2H-chromen-7-yl]oxy]-4,5-bis(oxidanyl)oxan-3-yl]oxy-6-methyl-oxane-3,4,5-triol | n/a | |
| 51 | P14174_IPA | IPA | DB02325 | 3776 | CHEMBL582 | ISOPROPYL ALCOHOL | n/a | |
| 52 | P14174_LE2 | LE2 | n/a | 23047654 | n/a | N-(2-phenylethyl)thioformamide | n/a | |
| 53 | P14174_LE3 | LE3 | n/a | 137349688 | n/a | N-{4-[(R)-methylsulfinyl]butyl}thioformamide | n/a | |
| 54 | P14174_MRI | MRI | DB16770 | 5281670 | CHEMBL28626 | 2-[2,4-bis(oxidanyl)phenyl]-3,5,7-tris(oxidanyl)chromen-4-one | n/a | |
| 55 | P14174_MT1 | MT1 | n/a | 444319;69085264; | n/a | N-(4-{[(2,4-DIAMINOPTERIDIN-1-IUM-6-YL)METHYL](METHYL)AMINO}BENZOYL)-L-GLUTAMIC ACID | n/a | |
| 56 | P14174_MYC | MYC | DB02375 | 5281672 | CHEMBL164 | 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE | n/a | |
| 57 | P14174_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 58 | P14174_NVS | NVS | n/a | 11492761 | n/a | 7-hydroxy-3-(4-methoxyphenyl)-3,4-dihydro-2H-1,3-benzoxazin-2-one | n/a | |
| 59 | P14174_OX3 | OX3 | DB08333 | 135616914 | CHEMBL253951 | 4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME | n/a | |
| 60 | P14174_OX4 | OX4 | DB08334 | 135566317 | n/a | 3-FLUORO-4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME | n/a | |
| 61 | P14174_OX5 | OX5 | DB08335 | 135908260 | CHEMBL256315 | 4-HYDROXYBENZALDEHYDE O-(3,3-DIMETHYLBUTANOYL)OXIME | n/a | |
| 62 | P14174_PMS | PMS | DB03297 | 7532 | CHEMBL1171433 | phenylmethanesulfonic acid | n/a | |
| 63 | P14174_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 64 | P14174_RW1 | RW1 | n/a | 18923 | CHEMBL1235765 | 4-phenylpyrimidine | n/a | |
| 65 | P14174_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 66 | P14174_XV1 | XV1 | n/a | 44251514 | n/a | 7-(2-fluorobenzyl)quinolin-8-ol | n/a | |
| 67 | P14174_Y0X | Y0X | n/a | n/a | CHEMBL311909 | 6,6'-[(3,3'-dimethoxybiphenyl-4,4'-diyl)di(E)diazene-2,1-diyl]bis(4-amino-5-hydroxynaphthalene-1,3-disulfonic acid) | n/a | |
| 68 | P14174_YZ9 | YZ9 | DB02728 | 5289613 | CHEMBL155103 | 7-HYDROXY-2-OXO-CHROMENE-3-CARBOXYLIC ACID ETHYL ESTER | n/a | Ki(nM) = 7400.0 IC50(nM) = 18600.0 |
| 69 | P14174_ZEC | ZEC | DB08765 | 6852129 | CHEMBL6685 | 6-HYDROXY-1,3-BENZOTHIAZOLE-2-SULFONAMIDE | inhibitor | |
| 70 | P14174_ZIN | ZIN | n/a | 44251516 | n/a | 7-(pyridin-2-ylmethyl)quinolin-8-ol | n/a |