Gene name: pol
Protein name: Pro-Pol polyprotein (Pr125Pol)
List of molecules and drugs that interact with protein P14350
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P14350_19C | 19C | n/a | n/a | n/a | 2-[(3-chloranyl-4-fluoranyl-phenyl)methyl]-6,7-bis(oxidanyl)isoindol-1-one | n/a | |
| 2 | P14350_4RT | 4RT | n/a | 86577668 | CHEMBL3623815 | (1R,2S,5R)-8'-(3-chloro-4-fluorobenzyl)-6'-hydroxy-1-(hydroxymethyl)-2'-methyl-9',10'-dihydro-2'H-spiro[bicyclo[3.1.0]hexane-2,3'-imidazo[5,1-a][2,6]naphthyridine]-1',5',7'(8'H)-trione | n/a | |
| 3 | P14350_8G1 | 8G1 | n/a | 124222745 | CHEMBL4087770 | (3R)-8-[(3-chloro-4-fluorophenyl)methyl]-6-hydroxy-1,5,7-trioxo-1,2',3',5,7,8,9,10-octahydro-2H-spiro[imidazo[5,1-a][2,6]naphthyridine-3,1'-indene]-7'-carbonitrile | n/a | |
| 4 | P14350_8G4 | 8G4 | n/a | 124222744 | n/a | (1S,2S,5R)-8'-[(3-chloro-4-fluorophenyl)methyl]-2'-[2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl]-6'-hydroxy-9',10'-dihydro-2'H-spiro[bicyclo[3.1.0]hexane-2,3'-imidazo[5,1-a][2,6]naphthyridine]-1',5',7'(8'H)-trione | n/a | |
| 5 | P14350_BF3 | BF3 | n/a | 45273166 | CHEMBL556473 | 2-(3-chloro-2-fluorobenzyl)-4,5-dihydroxy-1H-isoindole-1,3(2H)-dione | n/a | |
| 6 | P14350_CI4 | CI4 | n/a | 44189323 | CHEMBL549886 | 2-(3-chloro-2-fluorobenzyl)-6,7-dihydroxy-2,3-dihydro-1H-isoindol-1-one | n/a | |
| 7 | P14350_CIJ | CIJ | n/a | 25196811 | CHEMBL559284 | 2-(3-chloro-4-fluorobenzyl)-4,5-dihydroxy-1H-isoindole-1,3(2H)-dione | n/a | |
| 8 | P14350_DLU | DLU | DB08930 | 54726191 | CHEMBL1229211 | (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide | n/a | |
| 9 | P14350_ELV | ELV | DB09101 | 5277135 | CHEMBL204656 | 6-(3-chloro-2-fluorobenzyl)-1-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | n/a | |
| 10 | P14350_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 11 | P14350_HEZ | HEZ | DB02210 | 12374 | CHEMBL458616 | HEXANE-1,6-DIOL | n/a | |
| 12 | P14350_M76 | M76 | n/a | 136504223 | CHEMBL3288269 | N-(4-fluorobenzyl)-2,3-dihydroxy-1-oxo-1,2-dihydroisoquinoline-4-carboxamide | n/a | |
| 13 | P14350_MES | MES | DB03814 | 78165;4478249; | CHEMBL1234276 | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | n/a | |
| 14 | P14350_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 15 | P14350_MN | MN | n/a | 27854 | n/a | MANGANESE (II) ION | n/a | |
| 16 | P14350_NH4 | NH4 | n/a | 223;16741146; | n/a | AMMONIUM ION | n/a | |
| 17 | P14350_OUY | OUY | n/a | 117696953 | CHEMBL4072381 | methyl 3-[5-azanyl-6-[[2,4-bis(fluoranyl)phenyl]methylcarbamoyl]-8-oxidanyl-7-oxidanylidene-1,8-naphthyridin-3-yl]propanoate | n/a | |
| 18 | P14350_QUW | QUW | n/a | 117697114 | CHEMBL4101122 | 4-azanyl-N-[[2,4-bis(fluoranyl)phenyl]methyl]-1-oxidanyl-2-oxidanylidene-6-(5-oxidanylpentyl)-1,8-naphthyridine-3-carboxamide | n/a | |
| 19 | P14350_R7K | R7K | n/a | 117706878 | n/a | ~{N}-[[2,4-bis(fluoranyl)phenyl]methyl]-5-(hydroxymethyl)-1,4-bis(oxidanyl)-2-oxidanylidene-1,8-naphthyridine-3-carboxamide | n/a | |
| 20 | P14350_R7N | R7N | n/a | 117697427 | n/a | 4-azanyl-~{N}-[[2,4-bis(fluoranyl)phenyl]methyl]-6-[2-(2-morpholin-4-ylethylsulfonyl)ethyl]-1-oxidanyl-2-oxidanylidene-1,8-naphthyridine-3-carboxamide | n/a | |
| 21 | P14350_RLT | RLT | DB06817 | 54671008 | CHEMBL254316 | N-(4-fluorobenzyl)-5-hydroxy-1-methyl-2-(1-methyl-1-{[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino}ethyl)-6-oxo-1,6-di hydropyrimidine-4-carboxamide | n/a | |
| 22 | P14350_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 23 | P14350_VHT | VHT | n/a | 90644689 | CHEMBL3288829 | methyl 2-[[3-[[2,4-bis(fluoranyl)phenyl]methylcarbamoyl]-1-oxidanyl-2-oxidanylidene-1,8-naphthyridin-4-yl]amino]ethanoate | n/a | |
| 24 | P14350_WA5 | WA5 | n/a | n/a | n/a | 4-azanylidene-N-[[2,4-bis(fluoranyl)phenyl]methyl]-1-oxidanyl-2-oxidanylidene-1,8-naphthyridine-3-carboxamide | n/a | |
| 25 | P14350_X2P | X2P | n/a | 86577515 | CHEMBL3623814 | (1R,2R,5S)-8'-(3-chloro-4-fluorobenzyl)-6'-hydroxy-2'-[(2S)-2-hydroxypropyl]-9',10'-dihydro-2'H-spiro[bicyclo[3.1.0]hexane-2,3'-imidazo[5,1-a][2,6]naphthyridine]-1',5',7'(8'H)-trione | n/a | |
| 26 | P14350_XXJ | XXJ | n/a | 117696807 | n/a | 4-azanyl-N-[[2,4-bis(fluoranyl)phenyl]methyl]-1-oxidanyl-2-oxidanylidene-6-[2-(phenylsulfonyl)ethyl]-1,8-naphthyridine-3-carboxamide | n/a | |
| 27 | P14350_XZ2 | XZ2 | n/a | 66553092 | n/a | 2-(3-chloro-4-fluorobenzyl)-6,7-dihydroxy-N,N-dimethyl-1-oxo-2,3-dihydro-1H-isoindole-4-sulfonamide | n/a | |
| 28 | P14350_XZ4 | XZ4 | n/a | 117696735 | CHEMBL4105456 | methyl 2-[[3-[[2,4-bis(fluoranyl)phenyl]methylcarbamoyl]-7-methoxy-1-oxidanyl-2-oxidanylidene-1,8-naphthyridin-4-yl]amino]ethanoate | n/a | |
| 29 | P14350_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 30 | P14350_ZYN | ZYN | n/a | 54680316 | CHEMBL1237000 | 6-(3-chloro-4-fluorobenzyl)-4-hydroxy-N,N-dimethyl-2-(1-methylethyl)-3,5-dioxo-2,3,5,6,7,8-hexahydro-2,6-naphthyridine-1-carboxamide | n/a | |
| 31 | P14350_ZYO | ZYO | n/a | 54731643 | n/a | (6S)-2-(3-chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-6-methyl-4-(5-methyl-1,1-dioxido-1,2,5-thiadiazolidin-2-yl)-7,8-dihydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-1,9(2H,6H)-dione | n/a | |
| 32 | P14350_ZYP | ZYP | n/a | 457930 | CHEMBL414850 | 5-(1,1-dioxido-1,2-thiazinan-2-yl)-N-(4-fluorobenzyl)-8-hydroxy-1,6-naphthyridine-7-carboxamide | n/a | |
| 33 | P14350_ZYY | ZYY | n/a | 54710713 | n/a | N-[(6S)-2-(4-fluorobenzyl)-10-hydroxy-6-methyl-8-(1-methylethyl)-1,9-dioxo-1,2,6,7,8,9-hexahydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazin-4-yl]-N-methylmethanesulfonamide | n/a | |
| 34 | P14350_ZZV | ZZV | n/a | 16097721 | CHEMBL513189 | N-[7-(4-fluorobenzyl)-9-hydroxy-8-oxo-7,8-dihydro-6H-pyrrolo[3,4-g]quinolin-5-yl]-N-methylmethanesulfonamide | n/a | |
| 35 | P14350_ZZW | ZZW | n/a | 3013459 | n/a | 9-(4-fluorobenzyl)-N-hydroxy-9H-beta-carboline-3-carboxamide | n/a | |
| 36 | P14350_ZZX | ZZX | n/a | 54698642 | CHEMBL1237018 | (6S)-2-(3-chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-1,2,6,7,8,9-hexahydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide | n/a |