Gene name: GABRA1
Protein name: Gamma-aminobutyric acid receptor
List of molecules and drugs that interact with protein P14867
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P14867_A8W | A8W | n/a | 105074 | CHEMBL1179605 | Pregnenolone sulfate | n/a | |
| 2 | P14867_ABU | ABU | DB02530 | 119;6992099; | CHEMBL96 | GAMMA-AMINO-BUTANOIC ACID | inhibitor | Ki(nM) = 21.37 EC50(nM) = 1778.0 |
| 3 | P14867_D10 | D10 | n/a | 15600 | CHEMBL134537 | DECANE | n/a | |
| 4 | P14867_DZP | DZP | DB00829 | 3016 | CHEMBL12 | 7-CHLORO-1-METHYL-5-PHENYL-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE | ligand | Ki(nM) = 12.0 Kd(nM) = 36.0 EC50(nM) = 85.0 |
| 5 | P14867_FYP | FYP | DB01205 | 3373 | CHEMBL407 | ethyl 8-fluoro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate | antagonist | Ki(nM) = 0.48 |
| 6 | P14867_HEX | HEX | n/a | 8058 | CHEMBL15939 | HEXANE | n/a | |
| 7 | P14867_J94 | J94 | n/a | 104872 | CHEMBL515679 | (5S)-6,6-dimethyl-5-[(6R)-8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl]-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-6-ium | n/a | |
| 8 | P14867_MAN | MAN | n/a | 185698 | CHEMBL365590 | alpha-D-mannopyranose | n/a | |
| 9 | P14867_NAG | NAG | DB00141 | 24139 | CHEMBL447878 | 2-acetamido-2-deoxy-beta-D-glucopyranose | n/a | |
| 10 | P14867_OCT | OCT | n/a | 356 | CHEMBL134886 | N-OCTANE | n/a | |
| 11 | P14867_PFL | PFL | DB00818 | 4943 | CHEMBL526 | 2,6-BIS(1-METHYLETHYL)PHENOL | positive allosteric modulator | IC50(nM) = 8000.0 EC50(nM) = 1995.26 |
| 12 | P14867_PIO | PIO | n/a | 9543520 | n/a | [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | n/a | |
| 13 | P14867_POV | POV | n/a | 10908846 | n/a | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | n/a | |
| 14 | P14867_PTY | PTY | n/a | 446872 | n/a | PHOSPHATIDYLETHANOLAMINE | n/a | |
| 15 | P14867_Q3G | Q3G | n/a | 145946117 | n/a | O-[(R)-[(2S)-2-(hexadecanoyloxy)-3-(octadecanoyloxy)propoxy](hydroxy)phosphoryl]-D-serine | n/a | |
| 16 | P14867_R5R | R5R | DB00425 | 5732 | CHEMBL911 | Zolpidem | agonist | Ki(nM) = 15.5 IC50(nM) = 14.0 EC50(nM) = 191.0 |
| 17 | P14867_R63 | R63 | n/a | 104999 | CHEMBL1256850 | methyl 4-ethyl-6,7-dimethoxy-9H-pyrido[3,4-b]indole-3-carboxylate | n/a | |
| 18 | P14867_RI5 | RI5 | n/a | 442292 | CHEMBL47244 | (1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-2a-hydroxy-8b-methyl-9-(prop-1-en-2-yl)hexahydro-3,6-methano-1,5,7-trioxacyclopenta[ij]c yclopropa[a]azulene-4,8(3H)-dione | n/a | |
| 19 | P14867_UND | UND | n/a | 14257 | CHEMBL132474 | UNDECANE | n/a | |
| 20 | P14867_UQA | UQA | DB01174 | 4763 | CHEMBL40 | 5-ethyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione | potentiator | |
| 21 | P14867_V8D | V8D | DB00292 | 667484 | CHEMBL681 | Etomidate | agonist | IC50(nM) = 577000.0 EC50(nM) = 1200.0 |
| 22 | P14867_Y01 | Y01 | n/a | 65082 | n/a | CHOLESTEROL HEMISUCCINATE | n/a | |
| 23 | P14867_Y4B | Y4B | DB11859 | 92786 | CHEMBL207538 | allopregnanolone | positive allosteric modulator | |
| 24 | P14867_ZWY | ZWY | DB05804 | 12594 | CHEMBL259898 | 17-oxoandrost-5-en-3beta-yl hydrogen sulfate | n/a | |
| 25 | P14867_DB00241 | n/a | DB00241 | n/a | n/a | Butalbital | positive allosteric modulator | |
| 26 | P14867_TOR | TOR | DB00273 | 5284627 | CHEMBL220492 | Topiramate | agonist | |
| 27 | P14867_DB00306 | n/a | DB00306 | n/a | n/a | Talbutal | potentiator | |
| 28 | P14867_DB00312 | n/a | DB00312 | n/a | n/a | Pentobarbital | positive allosteric modulator | IC50(nM) = 1000000.0 |
| 29 | P14867_DB00371 | n/a | DB00371 | n/a | n/a | Meprobamate | agonist | |
| 30 | P14867_DB00395 | n/a | DB00395 | n/a | n/a | Carisoprodol | activator | |
| 31 | P14867_DB00402 | n/a | DB00402 | n/a | n/a | Eszopiclone | potentiator | |
| 32 | P14867_DB00418 | n/a | DB00418 | n/a | n/a | Secobarbital | potentiator | |
| 33 | P14867_VOK | VOK | DB00463 | 4099 | CHEMBL450 | Metharbital | potentiator | |
| 34 | P14867_DB00466 | n/a | DB00466 | n/a | n/a | Picrotoxin | antagonist | |
| 35 | P14867_DB00474 | n/a | DB00474 | n/a | n/a | Methohexital | antagonist | |
| 36 | P14867_DB00543 | n/a | DB00543 | n/a | n/a | Amoxapine | antagonist | |
| 37 | P14867_DB00599 | n/a | DB00599 | n/a | n/a | Thiopental | potentiator | |
| 38 | P14867_DB00753 | n/a | DB00753 | n/a | n/a | Isoflurane | positive allosteric modulator | |
| 39 | P14867_DB00794 | n/a | DB00794 | n/a | n/a | Primidone | potentiator | |
| 40 | P14867_DB00837 | n/a | DB00837 | n/a | n/a | Progabide | agonist | |
| 41 | P14867_DB00849 | n/a | DB00849 | n/a | n/a | Methylphenobarbital | potentiator | |
| 42 | P14867_EOH | EOH | DB00898 | 702 | CHEMBL545 | Ethanol | agonist | |
| 43 | P14867_DB00962 | n/a | DB00962 | n/a | n/a | Zaleplon | potentiator | EC50(nM) = 290.0 |
| 44 | P14867_DB01028 | n/a | DB01028 | n/a | n/a | Methoxyflurane | agonist | |
| 45 | P14867_DB01107 | n/a | DB01107 | n/a | n/a | Methyprylon | positive allosteric modulator | |
| 46 | P14867_DB01154 | n/a | DB01154 | n/a | n/a | Thiamylal | agonist | |
| 47 | P14867_DB01159 | n/a | DB01159 | n/a | n/a | Halothane | positive allosteric modulator | |
| 48 | P14867_DB01198 | n/a | DB01198 | n/a | n/a | Zopiclone | potentiator | |
| 49 | P14867_DB01346 | n/a | DB01346 | n/a | n/a | Quinidine barbiturate | potentiator | |
| 50 | P14867_DB01351 | n/a | DB01351 | n/a | n/a | Amobarbital | potentiator | |
| 51 | P14867_DB01352 | n/a | DB01352 | n/a | n/a | Aprobarbital | potentiator | |
| 52 | P14867_DB01353 | n/a | DB01353 | n/a | n/a | Butobarbital | potentiator | |
| 53 | P14867_DB01354 | n/a | DB01354 | n/a | n/a | Heptabarbital | potentiator | |
| 54 | P14867_DB01355 | n/a | DB01355 | n/a | n/a | Hexobarbital | potentiator | |
| 55 | P14867_DB01437 | n/a | DB01437 | n/a | n/a | Glutethimide | agonist | |
| 56 | P14867_DB01483 | n/a | DB01483 | n/a | n/a | Barbital | potentiator | |
| 57 | P14867_DB01496 | n/a | DB01496 | n/a | n/a | Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione | potentiator | |
| 58 | P14867_DB01567 | n/a | DB01567 | n/a | n/a | Fludiazepam | potentiator | |
| 59 | P14867_DB06470 | n/a | DB06470 | n/a | n/a | Clomethiazole | n/a | |
| 60 | P14867_DB12458 | n/a | DB12458 | n/a | n/a | Muscimol | n/a |