Gene name: IDO1
Protein name: Indoleamine 2,3-dioxygenase 1
List of molecules and drugs that interact with protein P14902
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P14902_5PF | 5PF | n/a | 102006362 | n/a | (1~{R})-1-cyclohexyl-2-[(5~{S})-6-fluoranyl-5~{H}-imidazo[1,5-b]isoindol-5-yl]ethanol | n/a | |
| 2 | P14902_5PJ | 5PJ | n/a | 137348389 | n/a | 1-cyclohexyl-2-[(5~{S})-6-fluoranyl-5~{H}-imidazo[1,5-b]isoindol-5-yl]ethanone | n/a | |
| 3 | P14902_5PK | 5PK | n/a | 70874783 | CHEMBL3752711 | (1~{R})-1-cyclohexyl-2-[(5~{S})-5~{H}-imidazo[1,5-b]isoindol-5-yl]ethanol | n/a | |
| 4 | P14902_6IZ | 6IZ | n/a | 138609036 | n/a | 3-[4-(1H-benzimidazol-2-yl)phenyl]-N-(4-fluorophenyl)oxetane-3-carboxamide | n/a | |
| 5 | P14902_6RI | 6RI | n/a | 138609137 | CHEMBL5192977 | N-(4-fluorophenyl)-3-{4-[4-(hydroxymethyl)-6-(trifluoromethyl)pyridin-3-yl]phenyl}oxetane-3-carboxamide | n/a | |
| 6 | P14902_6ZI | 6ZI | n/a | 138609057 | CHEMBL5192057 | 3-[4-(6-cyclopropylpyridin-3-yl)phenyl]-N-(4-fluorophenyl)oxetane-3-carboxamide | n/a | |
| 7 | P14902_ACY | ACY | DB03166 | 176;21980959;160748163; | CHEMBL539 | ACETIC ACID | n/a | |
| 8 | P14902_ALA | ALA | DB00160 | 5950;7311724; | CHEMBL279597 | ALANINE | n/a | |
| 9 | P14902_AOJ | AOJ | n/a | 118512017 | CHEMBL4061767 | (3R)-3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione | n/a | |
| 10 | P14902_BBJ | BBJ | DB11717 | 135564890 | CHEMBL3545369 | N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-{[2-(sulfamoylamino)ethyl]amino}-1,2,5-oxadiazole-3-carboximidamide | inhibitor | |
| 11 | P14902_BEZ | BEZ | DB03793 | 243;20144841; | CHEMBL541 | BENZOIC ACID | n/a | |
| 12 | P14902_C4V | C4V | n/a | 118676157 | CHEMBL4777480 | (1R,2S)-2-(4-[bis(2-methylpropyl)amino]-3-{[(4-methylphenyl)carbamoyl]amino}phenyl)cyclopropane-1-carboxylic acid | n/a | |
| 13 | P14902_C51 | C51 | n/a | n/a | n/a | (2R)-N-(4-cyanophenyl)-2-[cis-4-(quinolin-4-yl)cyclohexyl]propanamide | n/a | |
| 14 | P14902_C82 | C82 | n/a | 75202656 | CHEMBL4443463 | ~{N}-(4-chlorophenyl)-1~{H}-1,2,3-triazol-5-amine | n/a | |
| 15 | P14902_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 16 | P14902_CMO | CMO | DB11588 | 281 | CHEMBL1231840 | CARBON MONOXIDE | n/a | |
| 17 | P14902_CYN | CYN | n/a | 5975 | n/a | CYANIDE ION | n/a | |
| 18 | P14902_DO9 | DO9 | n/a | 146018670 | CHEMBL4549501 | 1-(4-cyanophenyl)-3-[[3-(2-cyclopropylethynyl)imidazo[2,1-b][1,3]thiazol-5-yl]methyl]thiourea | n/a | |
| 19 | P14902_DU6 | DU6 | n/a | 146018671 | CHEMBL4591006 | 1-(4-cyanophenyl)-3-[[3-(2-cyclopropylethynyl)imidazo[2,1-b][1,3]thiazol-5-yl]methyl]urea | n/a | |
| 20 | P14902_DYC | DYC | n/a | 4574587 | CHEMBL4556305 | 3-(4-bromophenyl)imidazo[2,1-b][1,3]thiazole | n/a | |
| 21 | P14902_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 22 | P14902_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 23 | P14902_H7P | H7P | DB14986 | n/a | CHEMBL4161733 | (2R)-N-(4-chlorophenyl)-2-[cis-4-(6-fluoroquinolin-4-yl)cyclohexyl]propanamide | n/a | |
| 24 | P14902_HEM | HEM | DB18267 | n/a | n/a | PROTOPORPHYRIN IX CONTAINING FE | n/a | |
| 25 | P14902_HQJ | HQJ | n/a | 45120708 | CHEMBL4871575 | 4-(3-chlorophenyl)-1H-imidazole | n/a | |
| 26 | P14902_HQM | HQM | n/a | 118684055 | n/a | (1R,2S)-2-(4-[cyclohexyl(2-methylpropyl)amino]-3-{[(4-methylphenyl)carbamoyl]amino}phenyl)cyclopropane-1-carboxylic acid | n/a | |
| 27 | P14902_HQS | HQS | n/a | 135567420 | CHEMBL4452336 | N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-{[2-(sulfamoylamino)ethyl]sulfanyl}-1,2,5-oxadiazole-3-carboximidamide | n/a | |
| 28 | P14902_HS0 | HS0 | n/a | 24728063 | CHEMBL5219838 | 6-bromanyl-1~{H}-indazol-4-amine | n/a | |
| 29 | P14902_HU0 | HU0 | n/a | 132528948 | CHEMBL3972619 | 4-[[(6-bromanyl-1~{H}-indazol-4-yl)amino]methyl]phenol | n/a | |
| 30 | P14902_HU3 | HU3 | n/a | 156009086 | CHEMBL5220396 | (1~{S},2~{R})-2-[[(6-bromanyl-1~{H}-indazol-4-yl)amino]methyl]cyclohexan-1-ol | n/a | |
| 31 | P14902_HU6 | HU6 | n/a | 156022739 | CHEMBL5219865 | (1~{R},2~{S})-2-[[(6-bromanyl-1~{H}-indazol-4-yl)amino]methyl]cyclohexan-1-ol | n/a | |
| 32 | P14902_HU9 | HU9 | n/a | 156009088 | CHEMBL5221020 | (1~{R},2~{S})-2-[[(5-bromanyl-1~{H}-indazol-4-yl)amino]methyl]cyclohexan-1-ol | n/a | |
| 33 | P14902_HUC | HUC | n/a | 156009089 | CHEMBL5218978 | 6-bromanyl-~{N}-[[(1~{S},2~{S})-2-chloranylcyclohexyl]methyl]-1~{H}-indazol-4-amine | n/a | |
| 34 | P14902_IUU | IUU | n/a | 135424953 | CHEMBL584991 | 4-Amino-N-(3-chloro-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboxamidine | n/a | |
| 35 | P14902_JTB | JTB | n/a | 135981331 | CHEMBL2148074 | 4-chloranyl-2-(2~{H}-1,2,3-triazol-4-yl)phenol | n/a | |
| 36 | P14902_KYN | KYN | DB02070 | 161166;6971029; | CHEMBL498416 | (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid | n/a | |
| 37 | P14902_LKP | LKP | DB15439 | n/a | CHEMBL3989951 | trans-4-{(1R)-2-[(5S)-6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl]-1-hydroxyethyl}cyclohexan-1-ol | n/a | |
| 38 | P14902_N2U | N2U | n/a | 164885964 | n/a | O2-tert-butyl O3-ethyl O6-methyl (2S,6R)-6-(1-methylindol-2-yl)-2,5-dihydro-1H-pyridine-2,3,6-tricarboxylate | n/a | |
| 39 | P14902_N39 | N39 | n/a | 164885965 | n/a | O1-tert-butyl O2-ethyl O5-methyl (E,5R)-5-(1-methylindol-2-yl)-5-[(4-methylphenyl)sulfonylamino]pent-2-ene-1,2,5-tricarboxylate | n/a | |
| 40 | P14902_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 41 | P14902_NFK | NFK | n/a | 439788;25202092; | CHEMBL3577708 | N'-Formylkynurenine | n/a | |
| 42 | P14902_NHE | NHE | DB03309 | 66898;3852474; | n/a | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID | n/a | |
| 43 | P14902_OIH | OIH | n/a | 150762701 | n/a | 1-[3-[(4-chloranyl-2-fluoranyl-phenyl)carbamoylamino]-4-[cyclohexyl(2-methylpropyl)amino]phenyl]pyrrole-2-carboxylic acid | n/a | |
| 44 | P14902_OXY | OXY | DB09140 | 977 | CHEMBL1234886 | OXYGEN MOLECULE | n/a | |
| 45 | P14902_OY4 | OY4 | n/a | 137297447 | CHEMBL4584522 | N-{2-[(4-{N-[(7S)-4-fluorobicyclo[4.2.0]octa-1,3,5-trien-7-yl]-N'-hydroxycarbamimidoyl}-1,2,5-oxadiazol-3-yl)sulfanyl]ethyl}acetamide | n/a | |
| 46 | P14902_PG4 | PG4 | n/a | 8200 | CHEMBL1235254 | TETRAETHYLENE GLYCOL | n/a | |
| 47 | P14902_PGE | PGE | DB02327 | 8172 | CHEMBL1235259 | TRIETHYLENE GLYCOL | n/a | |
| 48 | P14902_PIM | PIM | DB03254 | 69590 | CHEMBL14145 | 4-PHENYL-1H-IMIDAZOLE | inhibitor | |
| 49 | P14902_PKJ | PKJ | n/a | 1085108 | CHEMBL3342402 | N-(1,3-benzodioxol-5-yl)-2-{[5-(4-methylphenyl)[1,3]thiazolo[2,3-c][1,2,4]triazol-3-yl]sulfanyl}acetamide | n/a | |
| 50 | P14902_PKL | PKL | n/a | 118716433 | CHEMBL3342393 | N-[2-(3-chlorophenyl)ethyl]-3-(4-methylphenyl)imidazo[2,1-b][1,3]thiazole-5-carboxamide | n/a | |
| 51 | P14902_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 52 | P14902_QPV | QPV | n/a | 146018272 | CHEMBL4636709 | 3-chloro-N-{4-[1-(propylcarbamoyl)cyclobutyl]phenyl}benzamide | n/a | |
| 53 | P14902_RCN | RCN | n/a | 145734090 | CHEMBL4856775 | 4-chloranyl-2-(2~{H}-1,2,3-triazol-4-yl)aniline | n/a | |
| 54 | P14902_RCQ | RCQ | n/a | 21439075 | CHEMBL4871312 | 4-chloranyl-2-(1~{H}-1,2,4-triazol-5-yl)aniline | n/a | |
| 55 | P14902_RCT | RCT | n/a | 155559375 | CHEMBL4563970 | 4-(3-chloro-2-phenethylphenyl)-1H-1,2,3-triazole | n/a | |
| 56 | P14902_RCW | RCW | n/a | 62072644 | CHEMBL4847829 | 4-bromanyl-2-(4~{H}-1,2,4-triazol-3-yl)aniline | n/a | |
| 57 | P14902_SLW | SLW | n/a | n/a | n/a | 4-chloranyl-N-[(1R)-1-[(1S,5R)-3-quinolin-4-yloxy-6-bicyclo[3.1.0]hexanyl]propyl]benzamide | n/a | |
| 58 | P14902_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 59 | P14902_THJ | THJ | n/a | 1084 | n/a | THIOSULFATE | n/a | |
| 60 | P14902_TRP | TRP | DB00150 | 6305;6923516; | CHEMBL54976 | TRYPTOPHAN | binder | IC50(nM) = 498700.0 |
| 61 | P14902_U41 | U41 | n/a | n/a | n/a | 3-chloro-N-(3-{(2S)-1-[(4-fluorophenyl)amino]-1-oxopropan-2-yl}bicyclo[1.1.1]pentan-1-yl)benzamide | n/a | |
| 62 | P14902_U6G | U6G | n/a | 142580447 | CHEMBL4791214 | 4-chloro-N-{[1-(3-chlorobenzene-1-carbonyl)-1,2,3,4-tetrahydroquinolin-6-yl]methyl}benzamide | n/a | |
| 63 | P14902_URJ | URJ | n/a | 142580242 | CHEMBL4859249 | 4-fluoro-N-{1-[5-(2-methylpyrimidin-4-yl)-5,6,7,8-tetrahydro-1,5-naphthyridin-2-yl]cyclopropyl}benzamide | n/a | |
| 64 | P14902_XNL | XNL | n/a | 117094731 | n/a | (1~{R})-1-cyclohexyl-2-pyrido[3,4-b]indol-9-yl-ethanol | n/a | |
| 65 | P14902_Y9X | Y9X | n/a | 117805608 | CHEMBL5270232 | N-(4-methylphenyl)-N'-[(1P,2'P)-4-propoxy-5-propyl-2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-3-yl]urea | n/a | |
| 66 | P14902_YRM | YRM | n/a | 134814487 | CHEMBL4853212 | (5S)-6,6-dimethyl-8-[(4S)-7-(trifluoromethyl)imidazo[1,5-a]pyridin-5-yl]-1,3,8-triazaspiro[4.5]decane-2,4-dione | n/a | |
| 67 | P14902_YRP | YRP | n/a | n/a | n/a | (2R)-N-(4-chlorophenyl)-2-[(1R,3S,5S,6r)-3-(5,6-difluoro-1H-benzimidazol-1-yl)bicyclo[3.1.0]hexan-6-yl]propanamide | n/a | |
| 68 | P14902_ZCW | ZCW | n/a | 10685 | CHEMBL226545 | 2-(1H-indol-3-yl)ethanol | n/a | |
| 69 | P14902_DB00435 | n/a | DB00435 | n/a | n/a | Nitric Oxide | n/a | |
| 70 | P14902_P0T | P0T | DB09061 | 644019 | CHEMBL190461 | Cannabidiol | inhibitor | |
| 71 | P14902_DB14011 | n/a | DB14011 | n/a | n/a | Nabiximols | inhibitor |