Gene name: lef
Protein name: Lethal factor (LF)
List of molecules and drugs that interact with protein P15917
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P15917_0LX | 0LX | n/a | 54582019 | CHEMBL1760318 | (2S)-6-[(4-fluorobenzyl)amino]-2-[(2R)-2-(4-fluorophenyl)-2-methoxyethyl]-N-hydroxyhexanamide | n/a | |
| 2 | P15917_2ZL | 2ZL | n/a | 86277896 | n/a | N~2~-benzyl-N~2~-[(4-fluoro-3-methylphenyl)sulfonyl]-N-hydroxy-D-alaninamide | n/a | |
| 3 | P15917_30H | 30H | n/a | 86277897 | n/a | N~2~-[(4-fluoro-3-methylphenyl)sulfonyl]-N-hydroxy-N~2~-(pyridin-3-ylmethyl)-D-alaninamide | n/a | |
| 4 | P15917_30O | 30O | n/a | 86277898 | n/a | N~2~-[(4-fluoro-3-methylphenyl)sulfonyl]-N-hydroxy-N~2~-(4-nitrobenzyl)-D-alaninamide | n/a | |
| 5 | P15917_30P | 30P | n/a | 86277899 | n/a | N~2~-(3-aminobenzyl)-N~2~-[(4-fluoro-3-methylphenyl)sulfonyl]-N-hydroxy-D-alaninamide | n/a | |
| 6 | P15917_30R | 30R | n/a | 86277900 | CHEMBL3635080 | N~2~-[4-(aminomethyl)benzyl]-N~2~-[(4-fluoro-3-methylphenyl)sulfonyl]-N-hydroxy-D-alaninamide | n/a | |
| 7 | P15917_407 | 407 | n/a | 6539679 | CHEMBL201868 | N~2~-[(4-fluoro-3-methylphenyl)sulfonyl]-N-hydroxy-D-alaninamide | n/a | |
| 8 | P15917_41R | 41R | n/a | 92044061 | n/a | N~2~-[(4-fluoro-3-methylphenyl)sulfonyl]-N-hydroxy-N~2~-(2-methylpropyl)-D-valinamide | n/a | |
| 9 | P15917_41S | 41S | n/a | 92044062 | n/a | N~2~-[(4-fluoro-3-methoxyphenyl)sulfonyl]-N-hydroxy-N~2~-(2-methylpropyl)-D-valinamide | n/a | |
| 10 | P15917_41T | 41T | n/a | 92044063 | n/a | N-hydroxy-N~2~-{[3-(methoxymethyl)phenyl]sulfonyl}-N~2~-(2-methylpropyl)-D-valinamide | n/a | |
| 11 | P15917_56P | 56P | n/a | 122196493 | CHEMBL3635071 | N~2~-(6-aminohexyl)-N~2~-[(4-fluoro-3-methylphenyl)sulfonyl]-N-hydroxy-D-alaninamide | n/a | |
| 12 | P15917_56Q | 56Q | n/a | 92044070 | CHEMBL3634955 | N~2~-[(4-fluoro-3-methylphenyl)sulfonyl]-N-hydroxy-N~2~-methyl-D-alaninamide | n/a | |
| 13 | P15917_56R | 56R | n/a | 92044071 | CHEMBL3635061 | N~2~-[3-(aminomethyl)benzyl]-N~2~-[(4-fluoro-3-methylphenyl)sulfonyl]-N-hydroxy-D-alaninamide | n/a | |
| 14 | P15917_915 | 915 | DB07290 | 4369384 | CHEMBL204593 | (2R)-2-{[(4-FLUORO-3-METHYLPHENYL)SULFONYL]AMINO}-N-HYDROXY-2-TETRAHYDRO-2H-PYRAN-4-YLACETAMIDE | n/a | Ki(nM) = 24.0 IC50(nM) = 54.0 |
| 15 | P15917_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 16 | P15917_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 17 | P15917_GM6 | GM6 | DB02255 | 132519 | CHEMBL19611 | 3-(N-HYDROXYCARBOXAMIDO)-2-ISOBUTYLPROPANOYL-TRP-METHYLAMIDE | inhibitor | |
| 18 | P15917_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 19 | P15917_MLI | MLI | DB02201 | 9084 | n/a | MALONATE ION | n/a | |
| 20 | P15917_NSC | NSC | DB04452 | 71166 | CHEMBL87223 | N,N'-BIS(4-AMINO-2-METHYLQUINOLIN-6-YL)UREA | inhibitor | Ki(nM) = 500.0 IC50(nM) = 3200.0 |
| 21 | P15917_PGE | PGE | DB02327 | 8172 | CHEMBL1235259 | TRIETHYLENE GLYCOL | n/a | |
| 22 | P15917_SD2 | SD2 | DB01883 | 5289343 | n/a | N-(SULFANYLACETYL)TYROSYLPROLYLMETHIONINAMIDE | inhibitor | |
| 23 | P15917_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 24 | P15917_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a |