Gene name: NQO2
Protein name: Ribosyldihydronicotinamide dehydrogenase [quinone]
List of molecules and drugs that interact with protein P16083
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P16083_0TX | 0TX | n/a | 639540 | CHEMBL250447 | (4S)-N~4~-(7-chloroquinolin-4-yl)-N~1~,N~1~-diethylpentane-1,4-diamine | n/a | |
| 2 | P16083_1PQ | 1PQ | n/a | 3044369 | CHEMBL249843 | (4S)-N~4~-(6-methoxyquinolin-8-yl)pentane-1,4-diamine | n/a | |
| 3 | P16083_372 | 372 | n/a | 71598535 | n/a | N-[(3R)-3-(cyanomethyl)-1-methyl-2-oxo-2,3-dihydro-1H-indol-5-yl]acetamide | n/a | |
| 4 | P16083_3ZU | 3ZU | n/a | n/a | CHEMBL576451 | (2S)-2-(4-aminophenyl)-1-hydroxy-5-methoxy-1,2-dihydro-3H-indol-3-one | n/a | |
| 5 | P16083_3ZV | 3ZV | n/a | 86288912 | CHEMBL3238540 | 5-methoxy-2-(4-methoxyphenyl)-3H-indol-3-one | n/a | |
| 6 | P16083_465 | 465 | n/a | 137348209 | n/a | 8-amino-7-chloro-1-methyl-6-(methylideneamino)-2-oxo-1,2-dihydropyrrolo[4,3,2-de]quinoline-4-carboxamide | n/a | |
| 7 | P16083_4X4 | 4X4 | n/a | 53317683 | n/a | N-[2-(2-methoxy-1H-dipyrido[2,3-a:3',2'-e]pyrrolizin-11-yl)ethyl]furan-2-carboxamide | n/a | |
| 8 | P16083_52X | 52X | n/a | 10092427 | CHEMBL511675 | methyl {3-[2-(acetylamino)ethyl]-2-iodo-1H-indol-5-yl}carbamate | n/a | |
| 9 | P16083_695 | 695 | n/a | 18175028 | CHEMBL1738752 | N-{2-[7-(methylsulfamoyl)naphthalen-1-yl]ethyl}acetamide | n/a | |
| 10 | P16083_6A1 | 6A1 | n/a | 137348439 | n/a | hydroxy(2-{[(5S)-6-hydroxy-8-methoxy-4,5-dihydro-3H-imidazo[4,5,1-de]acridin-5-yl]amino}ethyl)dimethylammonium | n/a | |
| 11 | P16083_6T0 | 6T0 | DB00724 | 57469 | CHEMBL1282 | 1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine | n/a | |
| 12 | P16083_6T2 | 6T2 | DB11832 | 10366136 | CHEMBL2105728 | 1-(2-{5-[(3-Methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine | n/a | |
| 13 | P16083_6T3 | 6T3 | DB11697 | 46216796 | CHEMBL2035187 | 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene | n/a | |
| 14 | P16083_79X | 79X | n/a | 9796175 | n/a | 2-hydroxy-8,9-dimethoxy-6H-isoindolo[2,1-a]indol-6-one | n/a | |
| 15 | P16083_A2Z | A2Z | n/a | 42618027 | CHEMBL492763 | 6,9-dimethyl[1,3]dioxolo[4,5-h]quinolin-8(9H)-one | n/a | |
| 16 | P16083_A7B | A7B | n/a | 782123 | CHEMBL453417 | 8-methoxy-4-methylquinolin-2(1H)-one | n/a | |
| 17 | P16083_AA | AA | n/a | 4601006;5124248; | n/a | 9-AMINOACRIDINE | n/a | |
| 18 | P16083_AD1 | AD1 | DB07339 | 23270857 | n/a | (3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione | n/a | |
| 19 | P16083_AO | AO | n/a | 5035218;5231310;44140562; | n/a | ACRIDINE ORANGE | n/a | |
| 20 | P16083_C09 | C09 | n/a | 11579618 | CHEMBL4081845 | 2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-4-amine | n/a | |
| 21 | P16083_CB1 | CB1 | DB04253 | 89105 | CHEMBL23330 | 5-(AZIRIDIN-1-YL)-2,4-DINITROBENZAMIDE | inhibitor | |
| 22 | P16083_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 23 | P16083_CLQ | CLQ | DB00608 | 444810 | CHEMBL252715 | N4-(7-CHLORO-QUINOLIN-4-YL)-N1,N1-DIETHYL-PENTANE-1,4-DIAMINE | n/a | IC50(nM) = 1500.0 |
| 24 | P16083_DM2 | DM2 | DB00997 | 31703 | CHEMBL53463 | DOXORUBICIN | n/a | |
| 25 | P16083_ET | ET | DB17031 | 3624;101633772; | CHEMBL48166 | ETHIDIUM | n/a | |
| 26 | P16083_EWQ | EWQ | n/a | 42618031 | CHEMBL493173 | 6,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one | n/a | |
| 27 | P16083_FAD | FAD | DB03147 | 643975 | CHEMBL1232653 | FLAVIN-ADENINE DINUCLEOTIDE | inhibitor | |
| 28 | P16083_FMN | FMN | DB03247 | 643976 | CHEMBL1201794 | FLAVIN MONONUCLEOTIDE | n/a | |
| 29 | P16083_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 30 | P16083_HGZ | HGZ | n/a | 42618032 | CHEMBL454226 | 6,7,8-trimethoxy-4-methylquinolin-2(1H)-one | n/a | |
| 31 | P16083_IMD | IMD | DB03366 | 444234;4434133;21983501; | n/a | IMIDAZOLE | n/a | |
| 32 | P16083_K17 | K17 | n/a | 5149739 | CHEMBL373937 | 4,5,6,7-TETRABROMO-BENZIMIDAZOLE | n/a | |
| 33 | P16083_K25 | K25 | DB04719 | 5326976 | CHEMBL376505 | 4,5,6,7-TETRABROMO-N,N-DIMETHYL-1H-BENZIMIDAZOL-2-AMINE | n/a | IC50(nM) = 484.0 Kd(nM) = 36.4 |
| 34 | P16083_LDP | LDP | DB00988 | 681 | CHEMBL59 | L-DOPAMINE | n/a | |
| 35 | P16083_M42 | M42 | n/a | 42618026 | CHEMBL482693 | 6-methyl[1,3]dioxolo[4,5-h]quinolin-8(9H)-one | n/a | |
| 36 | P16083_M49 | M49 | n/a | 71598534 | n/a | N-{(3R)-3-[2-(acetylamino)ethyl]-2-oxo-2,3-dihydro-1H-indol-5-yl}acetamide | n/a | |
| 37 | P16083_ML1 | ML1 | DB01065 | 896 | CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide | inhibitor | Ki(nM) = 28.0 IC50(nM) = 64.57 |
| 38 | P16083_ML2 | ML2 | DB08190 | 115348 | CHEMBL289233 | N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide | inhibitor | Ki(nM) = 6.5 IC50(nM) = 1100.0 |
| 39 | P16083_MRD | MRD | n/a | 5288845 | n/a | (4R)-2-METHYLPENTANE-2,4-DIOL | n/a | |
| 40 | P16083_MXX | MXX | DB08228 | 1504717 | CHEMBL490867 | 5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one | inhibitor | IC50(nM) = 4100.0 |
| 41 | P16083_MZC | MZC | n/a | 4284525 | CHEMBL504585 | methyl {3-[2-(acetylamino)ethyl]-1H-indol-5-yl}carbamate | n/a | |
| 42 | P16083_MZX | MZX | n/a | 269167 | CHEMBL493174 | 5,8-dimethoxy-4-methylquinolin-2(1H)-one | n/a | |
| 43 | P16083_O73 | O73 | n/a | 24771849 | n/a | 5-[(4-aminobutyl)amino]-1,2-dimethyl-3-[(4-nitrophenoxy)methyl]-1H-indole-4,7-dione | n/a | |
| 44 | P16083_RZW | RZW | n/a | 15306617 | CHEMBL449065 | 5,6,8-trimethoxy-1,4-dimethylquinolin-2(1H)-one | n/a | |
| 45 | P16083_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 46 | P16083_TE7 | TE7 | n/a | 11681568 | CHEMBL125750 | 5-{[2-(dimethylamino)ethyl]amino}-8-methoxy-6H-imidazo[4,5,1-de]acridin-6-one | n/a | |
| 47 | P16083_UXH | UXH | n/a | 25113669 | CHEMBL1945406 | 6,8-diamino-7-chloro-1-methyl-2-oxo-1,2-dihydropyrrolo[4,3,2-de]quinoline-4-carboxamide | n/a | |
| 48 | P16083_V0L | V0L | DB12048 | 68289010 | CHEMBL3334567 | volitinib | n/a | |
| 49 | P16083_V1Z | V1Z | n/a | 164885982 | n/a | 8-methyl-2-(4-methyl-3-piperazin-1-ylsulfonyl-phenyl)imidazo[1,2-a]pyridine | n/a | |
| 50 | P16083_VAP | VAP | n/a | 42618033 | CHEMBL492382 | 6,7,8-trimethoxy-1,4-dimethylquinolin-2(1H)-one | n/a | |
| 51 | P16083_VK3 | VK3 | DB00170 | 4055 | CHEMBL590 | MENADIONE | n/a | |
| 52 | P16083_VVV | VVV | n/a | 15306616 | CHEMBL493181 | 5,6,8-trimethoxy-4-methylquinolin-2(1H)-one | n/a | |
| 53 | P16083_XM5 | XM5 | DB08744 | 124075 | CHEMBL492762 | 6-methoxy-9-methyl[1,3]dioxolo[4,5-h]quinolin-8(9H)-one | n/a | IC50(nM) = 54100.0 |
| 54 | P16083_XRA | XRA | DB00457 | 4893 | CHEMBL2 | 2-[4-(furan-2-ylcarbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine | n/a | IC50(nM) = 7.8 |
| 55 | P16083_YTR | YTR | n/a | 42618029 | CHEMBL453233 | 7,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one | n/a | |
| 56 | P16083_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 57 | P16083_ZXZ | ZXZ | n/a | 97252 | CHEMBL60376 | 1,4-dimethylquinolin-2(1H)-one | n/a | |
| 58 | P16083_STI | STI | DB00619 | 5291 | CHEMBL941 | 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE | n/a | Ki(nM) = 39.0 IC50(nM) = 43.0 |
| 59 | P16083_STL | STL | DB02709 | 445154 | CHEMBL165 | RESVERATROL | n/a | Ki(nM) = 88.0 IC50(nM) = 450.0 Kd(nM) = 54.0 |
| 60 | P16083_NAI | NAI | DB00157 | 439153 | CHEMBL1234616 | NADH | n/a | |
| 61 | P16083_DB01087 | n/a | DB01087 | n/a | n/a | Primaquine | inhibitor | |
| 62 | P16083_CB3 | CB3 | DB03541 | 443388;5281971;135438608; | CHEMBL389051 | 10-Propargyl-5,8-Dideazafolic Acid | inhibitor | |
| 63 | P16083_QUE | QUE | DB04216 | 5280343 | CHEMBL50 | Quercetin | inhibitor |