P16234 PGFRA_HUMAN
Gene name: PDGFRA
Protein name: Platelet-derived growth factor

List of molecules and drugs that interact with protein P16234

#	DrugDomain Data	PBD ligand	DrugBank Accession	PubChem	ChEMBL	Name	Drug action	Affinity data
1	P16234_6T2	6T2	DB11832	10366136	CHEMBL2105728	1-(2-{5-[(3-Methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine	modulator
2	P16234_748	748	n/a	129318936	CHEMBL4247298	N-[2-(dimethylamino)ethyl]-N-[[4-[[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]carbamoyl]phenyl]methyl]pyridine-3-carboxamide	n/a
3	P16234_B49	B49	DB01268	5329102	CHEMBL535	N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide	inhibitor	IC50(nM) = 6.9 Kd(nM) = 0.79
4	P16234_CL	CL	n/a	312	n/a	CHLORIDE ION	n/a
5	P16234_NAG	NAG	DB00141	24139	CHEMBL447878	2-acetamido-2-deoxy-beta-D-glucopyranose	n/a
6	P16234_SO4	SO4	DB14546	1117	n/a	SULFATE ION	n/a
7	P16234_STI	STI	DB00619	5291	CHEMBL941	4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE	antagonist	Ki(nM) = 2.0 IC50(nM) = 2.0 Kd(nM) = 31.0 EC50(nM) = 90.0
8	P16234_DB06589	n/a	DB06589	n/a	n/a	Pazopanib	inhibitor	IC50(nM) = 71.0 Kd(nM) = 4.9
9	P16234_2K2	2K2	DB06595	9829523	CHEMBL608533	Midostaurin	antagonist
10	P16234_DB08896	n/a	DB08896	n/a	n/a	Regorafenib	inhibitor	IC50(nM) = 16.0
11	P16234_0LI	0LI	DB08901	24826799	CHEMBL1171837	Ponatinib	inhibitor	IC50(nM) = 1.1
12	P16234_LEV	LEV	DB09078	9823820	CHEMBL1289601	Lenvatinib	inhibitor
13	P16234_XIN	XIN	DB09079	9809715	CHEMBL502835	Nintedanib	inhibitor
14	P16234_AV9	AV9	DB11800	9911830	CHEMBL1289494	Tivozanib	inhibitor
15	P16234_2RC	2RC	DB12010	11671467	CHEMBL2103830	Fostamatinib	inhibitor
16	P16234_5SF	5SF	DB12147	67462786	CHEMBL3545376	Erdafitinib	substrate
17	P16234_DB12742	n/a	DB12742	n/a	n/a	Amuvatinib	modulator
18	P16234_DB14840	n/a	DB14840	n/a	n/a	Ripretinib	inhibitor