Gene name: FLT1
Protein name: Vascular endothelial growth
List of molecules and drugs that interact with protein P17948
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P17948_8ST | 8ST | DB07288 | 9797919 | CHEMBL101683 | N-(4-chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide | n/a | IC50(nM) = 180.0 |
| 2 | P17948_B3P | B3P | DB02676 | 125132 | CHEMBL63859 | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | n/a | |
| 3 | P17948_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 4 | P17948_CO | CO | n/a | 104729 | n/a | COBALT (II) ION | n/a | |
| 5 | P17948_CU | CU | n/a | 27099 | n/a | COPPER (II) ION | n/a | |
| 6 | P17948_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 7 | P17948_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 8 | P17948_NAG | NAG | DB00141 | 24139 | CHEMBL447878 | 2-acetamido-2-deoxy-beta-D-glucopyranose | n/a | |
| 9 | P17948_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 10 | P17948_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 11 | P17948_BAX | BAX | DB00398 | 216239 | CHEMBL1336 | Sorafenib | inhibitor | IC50(nM) = 10.0 Kd(nM) = 31.0 |
| 12 | P17948_B49 | B49 | DB01268 | 5329102 | CHEMBL535 | Sunitinib | inhibitor | Ki(nM) = 2.0 IC50(nM) = 1.0 Kd(nM) = 1.8 |
| 13 | P17948_DB04879 | n/a | DB04879 | n/a | n/a | Vatalanib | inhibitor | IC50(nM) = 54.0 Kd(nM) = 9.6 |
| 14 | P17948_DB05075 | n/a | DB05075 | n/a | n/a | TG-100801 | n/a | |
| 15 | P17948_DB05913 | n/a | DB05913 | n/a | n/a | OSI-930 | n/a | |
| 16 | P17948_DB05932 | n/a | DB05932 | n/a | n/a | Denibulin | n/a | |
| 17 | P17948_DB06080 | n/a | DB06080 | n/a | n/a | Linifanib | n/a | |
| 18 | P17948_DB06589 | n/a | DB06589 | n/a | n/a | Pazopanib | inhibitor | IC50(nM) = 10.0 Kd(nM) = 14.0 |
| 19 | P17948_AXI | AXI | DB06626 | 6450551 | CHEMBL1289926 | Axitinib | inhibitor | |
| 20 | P17948_DB08896 | n/a | DB08896 | n/a | n/a | Regorafenib | inhibitor | IC50(nM) = 1.5 |
| 21 | P17948_LEV | LEV | DB09078 | 9823820 | CHEMBL1289601 | Lenvatinib | inhibitor | |
| 22 | P17948_XIN | XIN | DB09079 | 9809715 | CHEMBL502835 | Nintedanib | inhibitor | |
| 23 | P17948_DB09221 | n/a | DB09221 | n/a | n/a | Polaprezinc | agonist | |
| 24 | P17948_AV9 | AV9 | DB11800 | 9911830 | CHEMBL1289494 | Tivozanib | inhibitor | |
| 25 | P17948_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor | |
| 26 | P17948_DB15685 | n/a | DB15685 | n/a | n/a | Selpercatinib | inhibitor |