P18089 ADA2B_HUMAN
Gene name: ADRA2B
Protein name: Alpha-2B adrenergic receptor

List of molecules and drugs that interact with protein P18089

#	DrugDomain Data	PBD ligand	DrugBank Accession	PubChem	ChEMBL	Name	Drug action	Affinity data
1	P18089_DB00246	n/a	DB00246	n/a	n/a	Ziprasidone	antagonist	Ki(nM) = 48.0
2	P18089_DB00248	n/a	DB00248	n/a	n/a	Cabergoline	antagonist
3	P18089_V8D	V8D	DB00292	667484	CHEMBL681	Etomidate	agonist
4	P18089_DB00363	n/a	DB00363	n/a	n/a	Clozapine	antagonist
5	P18089_LNR	LNR	DB00368	439260	CHEMBL1437	Norepinephrine	agonist	EC50(nM) = 62.0
6	P18089_DB00408	n/a	DB00408	n/a	n/a	Loxapine	binder	Ki(nM) = 107.6
7	P18089_XRA	XRA	DB00457	4893	CHEMBL2	Prazosin	binder	Ki(nM) = 13.0
8	P18089_J59	J59	DB00484	2435	CHEMBL844	Brimonidine	agonist	Ki(nM) = 954.99
9	P18089_GMJ	GMJ	DB00502	3559	CHEMBL54	Haloperidol	n/a	Ki(nM) = 480.0
10	P18089_CLU	CLU	DB00575	2803	CHEMBL134	Clonidine	agonist
11	P18089_H8G	H8G	DB00589	28864	CHEMBL157138	Lisuride	other/unknown	Ki(nM) = 0.5
12	P18089_DB00629	n/a	DB00629	n/a	n/a	Guanabenz	binder	Ki(nM) = 281.84
13	P18089_ALE	ALE	DB00668	5816;139148732;	CHEMBL679	Epinephrine	agonist
14	P18089_OR9	OR9	DB00714	6005	CHEMBL53	Apomorphine	agonist	Ki(nM) = 66.07
15	P18089_DB00726	n/a	DB00726	n/a	n/a	Trimipramine	other/unknown
16	P18089_DB00734	n/a	DB00734	n/a	n/a	Risperidone	antagonist	Ki(nM) = 8.5
17	P18089_DB00797	n/a	DB00797	n/a	n/a	Tolazoline	binder	Ki(nM) = 3162.28
18	P18089_DB00800	n/a	DB00800	n/a	n/a	Fenoldopam	antagonist
19	P18089_DB00925	n/a	DB00925	n/a	n/a	Phenoxybenzamine	antagonist	Ki(nM) = 3.5
20	P18089_J5C	J5C	DB00935	4636	CHEMBL762	Oxymetazoline	agonist	Ki(nM) = 213.0
21	P18089_DB00964	n/a	DB00964	n/a	n/a	Apraclonidine	agonist	Ki(nM) = 4.5
22	P18089_DB01018	n/a	DB01018	n/a	n/a	Guanfacine	binder	Ki(nM) = 1020.0
23	P18089_DB01136	n/a	DB01136	n/a	n/a	Carvedilol	antagonist
24	P18089_08Y	08Y	DB01200	31101	CHEMBL493	Bromocriptine	agonist	Ki(nM) = 34.67
25	P18089_DB01224	n/a	DB01224	n/a	n/a	Quetiapine	antagonist	Ki(nM) = 90.0
26	P18089_9SC	9SC	DB01238	60795	CHEMBL1112	Aripiprazole	antagonist	Ki(nM) = 102.0
27	P18089_DB01267	n/a	DB01267	n/a	n/a	Paliperidone	antagonist	Ki(nM) = 9.4
28	P18089_DB01392	n/a	DB01392	n/a	n/a	Yohimbine	antagonist	Ki(nM) = 0.32
29	P18089_DB01403	n/a	DB01403	n/a	n/a	Methotrimeprazine	antagonist
30	P18089_B40	B40	DB01577	10836	CHEMBL1201201	Metamfetamine	agonist
31	P18089_DB04846	n/a	DB04846	n/a	n/a	Celiprolol	antagonist
32	P18089_DB04855	n/a	DB04855	n/a	n/a	Dronedarone	antagonist
33	P18089_DB05271	n/a	DB05271	n/a	n/a	Rotigotine	antagonist
34	P18089_DB05461	n/a	DB05461	n/a	n/a	OPC-28326	n/a
35	P18089_NP1	NP1	DB05492	5276854	CHEMBL609728	Epicept NP-1	n/a
36	P18089_DB06148	n/a	DB06148	n/a	n/a	Mianserin	antagonist
37	P18089_DB06153	n/a	DB06153	n/a	n/a	Pizotifen	antagonist
38	P18089_DB06216	n/a	DB06216	n/a	n/a	Asenapine	antagonist	Ki(nM) = 0.49
39	P18089_DB06229	n/a	DB06229	n/a	n/a	Ocaperidone	n/a
40	P18089_DB06262	n/a	DB06262	n/a	n/a	Droxidopa	agonist
41	P18089_DB06694	n/a	DB06694	n/a	n/a	Xylometazoline	agonist	Ki(nM) = 1047.13
42	P18089_DB14185	n/a	DB14185	n/a	n/a	Aripiprazole lauroxil	n/a