P18825 ADA2C_HUMAN
Gene name: ADRA2C
Protein name: Alpha-2C adrenergic receptor

List of molecules and drugs that interact with protein P18825

#	DrugDomain Data	PBD ligand	DrugBank Accession	PubChem	ChEMBL	Name	Drug action	Affinity data
1	P18825_DB00246	n/a	DB00246	n/a	n/a	Ziprasidone	antagonist	Ki(nM) = 59.0
2	P18825_DB00248	n/a	DB00248	n/a	n/a	Cabergoline	antagonist
3	P18825_DB00363	n/a	DB00363	n/a	n/a	Clozapine	antagonist	Ki(nM) = 2.9
4	P18825_LNR	LNR	DB00368	439260	CHEMBL1437	Norepinephrine	agonist	Ki(nM) = 63.0 EC50(nM) = 794.0
5	P18825_DB00408	n/a	DB00408	n/a	n/a	Loxapine	binder	Ki(nM) = 79.9
6	P18825_J59	J59	DB00484	2435	CHEMBL844	Brimonidine	agonist	Ki(nM) = 44.0 EC50(nM) = 3.4
7	P18825_GMJ	GMJ	DB00502	3559	CHEMBL54	Haloperidol	n/a	Ki(nM) = 550.0
8	P18825_CLU	CLU	DB00575	2803	CHEMBL134	Clonidine	agonist
9	P18825_H8G	H8G	DB00589	28864	CHEMBL157138	Lisuride	other/unknown	Ki(nM) = 0.4
10	P18825_ERM	ERM	DB00696	8223	CHEMBL442	Ergotamine	n/a
11	P18825_OR9	OR9	DB00714	6005	CHEMBL53	Apomorphine	agonist	Ki(nM) = 36.31
12	P18825_DB00734	n/a	DB00734	n/a	n/a	Risperidone	antagonist	Ki(nM) = 1.3
13	P18825_DB00797	n/a	DB00797	n/a	n/a	Tolazoline	binder	Ki(nM) = 3715.35
14	P18825_DB00800	n/a	DB00800	n/a	n/a	Fenoldopam	antagonist
15	P18825_DB00925	n/a	DB00925	n/a	n/a	Phenoxybenzamine	antagonist
16	P18825_J5C	J5C	DB00935	4636	CHEMBL762	Oxymetazoline	agonist	Ki(nM) = 31.0
17	P18825_DB01136	n/a	DB01136	n/a	n/a	Carvedilol	antagonist
18	P18825_08Y	08Y	DB01200	31101	CHEMBL493	Bromocriptine	agonist	Ki(nM) = 28.18
19	P18825_DB01224	n/a	DB01224	n/a	n/a	Quetiapine	antagonist	Ki(nM) = 28.7
20	P18825_9SC	9SC	DB01238	60795	CHEMBL1112	Aripiprazole	antagonist	Ki(nM) = 37.0
21	P18825_DB01267	n/a	DB01267	n/a	n/a	Paliperidone	agonist	Ki(nM) = 11.0
22	P18825_DB01392	n/a	DB01392	n/a	n/a	Yohimbine	antagonist	Ki(nM) = 0.13 IC50(nM) = 27.1
23	P18825_DB01403	n/a	DB01403	n/a	n/a	Methotrimeprazine	antagonist
24	P18825_B40	B40	DB01577	10836	CHEMBL1201201	Metamfetamine	agonist
25	P18825_DB04846	n/a	DB04846	n/a	n/a	Celiprolol	antagonist
26	P18825_DB04855	n/a	DB04855	n/a	n/a	Dronedarone	antagonist
27	P18825_DB04946	n/a	DB04946	n/a	n/a	Iloperidone	antagonist	Ki(nM) = 16.2
28	P18825_DB05461	n/a	DB05461	n/a	n/a	OPC-28326	n/a
29	P18825_NP1	NP1	DB05492	5276854	CHEMBL609728	Epicept NP-1	n/a
30	P18825_DB06148	n/a	DB06148	n/a	n/a	Mianserin	antagonist
31	P18825_DB06153	n/a	DB06153	n/a	n/a	Pizotifen	antagonist
32	P18825_DB06216	n/a	DB06216	n/a	n/a	Asenapine	antagonist	Ki(nM) = 13.0
33	P18825_DB06229	n/a	DB06229	n/a	n/a	Ocaperidone	n/a
34	P18825_DB06262	n/a	DB06262	n/a	n/a	Droxidopa	agonist
35	P18825_DB06694	n/a	DB06694	n/a	n/a	Xylometazoline	agonist	Ki(nM) = 128.82
36	P18825_DB08815	n/a	DB08815	n/a	n/a	Lurasidone	antagonist
37	P18825_AG2	AG2	DB08838	199	CHEMBL58343	Agmatine	agonist
38	P18825_DB09128	n/a	DB09128	n/a	n/a	Brexpiprazole	antagonist
39	P18825_DB14185	n/a	DB14185	n/a	n/a	Aripiprazole lauroxil	n/a