Gene name: RXRA
Protein name: Retinoic acid receptor
List of molecules and drugs that interact with protein P19793
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P19793_1O8 | 1O8 | DB12316 | 9904203 | CHEMBL3098771 | (2E,4E,6Z,8E)-8-(3,4-dihydronaphthalen-1(2H)-ylidene)-3,7-dimethylocta-2,4,6-trienoic acid | n/a | |
| 2 | P19793_21P | 21P | n/a | 44141920 | n/a | 4-[2-(1,1,3,3-tetramethyl-2,3-dihydro-1H-1,3-benzodisilol-5-yl)-1,3-dioxolan-2-yl]benzoic acid | n/a | |
| 3 | P19793_29V | 29V | n/a | 137348039 | n/a | (3E,6Z,8E)-3,7-dimethyl-8-[(4S)-4-methyl-3,4-dihydronaphthalen-1(2H)-ylidene]octa-3,6-dienoic acid | n/a | |
| 4 | P19793_2E3 | 2E3 | n/a | 44566110 | CHEMBL491294 | (2E)-3-[4-hydroxy-3-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)phenyl]prop-2-enoic acid | n/a | |
| 5 | P19793_2QO | 2QO | n/a | 78350449 | n/a | (2E)-3-[6-hydroxy-3'-(prop-2-en-1-yl)biphenyl-3-yl]prop-2-enoic acid | n/a | |
| 6 | P19793_2VP | 2VP | n/a | 90644073 | CHEMBL3289659 | (2E,4E,6Z,8E)-3,7-dimethyl-8-(7-methyl-3,4-dihydronaphthalen-1(2H)-ylidene)octa-2,4,6-trienoic acid | n/a | |
| 7 | P19793_2VR | 2VR | n/a | 59444436 | CHEMBL3289660 | (2E,4E,6Z,8E)-3,7-dimethyl-8-(8-methyl-3,4-dihydronaphthalen-1(2H)-ylidene)octa-2,4,6-trienoic acid | n/a | |
| 8 | P19793_2VZ | 2VZ | n/a | 59444434 | CHEMBL3289658 | (2E,4E,6Z,8E)-3,7-dimethyl-8-(6-methyl-3,4-dihydronaphthalen-1(2H)-ylidene)octa-2,4,6-trienoic acid | n/a | |
| 9 | P19793_2W0 | 2W0 | n/a | 59444433 | CHEMBL3289657 | (2E,4E,6Z,8E)-3,7-dimethyl-8-(5-methyl-3,4-dihydronaphthalen-1(2H)-ylidene)octa-2,4,6-trienoic acid | n/a | |
| 10 | P19793_3RB | 3RB | n/a | 11461003 | CHEMBL3622719 | (2E,4E,6Z,8E)-3,7-dimethyl-8-(6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ylidene)octa-2,4,6-trienoic acid | n/a | |
| 11 | P19793_3SV | 3SV | n/a | n/a | n/a | (3S,7S,8E)-8-[3-ethyl-2-(3-methylbutyl)cyclohex-2-en-1-ylidene]-3,7-dimethyloctanoic acid | n/a | |
| 12 | P19793_3SW | 3SW | n/a | 11559459 | CHEMBL3622723 | (2E,4E,6Z,8E)-8-[3-cyclopropyl-2-(3-methylbutyl)cyclohex-2-en-1-ylidene]-3,7-dimethylocta-2,4,6-trienoic acid | n/a | |
| 13 | P19793_3T2 | 3T2 | n/a | 122192001 | CHEMBL3622724 | (2E,4E,6Z,8E)-3,7-dimethyl-8-[2-(3-methylbutyl)-3-(propan-2-yl)cyclohex-2-en-1-ylidene]octa-2,4,6-trienoic acid | n/a | |
| 14 | P19793_3TN | 3TN | n/a | 49866497 | n/a | (2E)-3-[4-HYDROXY-3-(3-METHOXY-5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)PHENYL]ACRYLIC ACID | n/a | |
| 15 | P19793_4CU | 4CU | n/a | 131800943 | n/a | (~{E})-3-[4-oxidanyl-3-(5-prop-2-enyl-2-propoxy-phenyl)phenyl]prop-2-enoic acid | n/a | |
| 16 | P19793_4TN | 4TN | n/a | 49866519 | n/a | (2E)-3-[3-(3-ETHOXY-5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)-4-HYDROXYPHENYL]ACRYLIC ACID | n/a | |
| 17 | P19793_4XW | 4XW | n/a | 137348297 | n/a | (5S,6S,9R,13R)-2,3-didehydro-5,6,7,8,9,10,11,12,13,14-decahydroretinoic acid | n/a | |
| 18 | P19793_5LO | 5LO | n/a | 118796352 | CHEMBL3781132 | 4-[(11S,15R)-4,4,7,7-Tetramethyl-16-oxatetracyclo[8.6.0.03,8.011,15]hexadeca-1(10),2,8-trien-11-yl]benzoic acid | n/a | |
| 19 | P19793_5TN | 5TN | n/a | 49866541 | n/a | (2E)-3-[4-HYDROXY-3-(5,5,8,8-TETRAMETHYL-3-PROPOXY-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)PHENYL]ACRYLIC ACID | n/a | |
| 20 | P19793_754 | 754 | n/a | 6442223 | CHEMBL109581 | (2E,4E,6Z)-3-methyl-7-(5,5,8,8-tetramethyl-3-propoxy-5,6,7,8-tetrahydronaphthalen-2-yl)octa-2,4,6-trienoic acid | n/a | |
| 21 | P19793_7A4 | 7A4 | n/a | 46224594 | CHEMBL2337793 | [(1Z)-5-fluoro-2-methyl-1-{[4-(propan-2-yl)phenyl]methylidene}-1H-inden-3-yl]acetic acid | n/a | |
| 22 | P19793_7BE | 7BE | n/a | 126842978 | n/a | (2~{R})-6,6,9,9-tetramethylspiro[3,4,7,8-tetrahydrobenzo[g]chromene-2,2'-3,4-dihydrochromene]-6'-carboxylic acid | n/a | |
| 23 | P19793_7O0 | 7O0 | n/a | 131800940 | n/a | (~{E})-3-[4-oxidanyl-3-[3-(phenylmethyl)phenyl]phenyl]prop-2-enoic acid | n/a | |
| 24 | P19793_9CR | 9CR | DB00523 | 449171 | CHEMBL705 | (9cis)-retinoic acid | agonist | Ki(nM) = 8.0 IC50(nM) = 29.0 Kd(nM) = 1.5 EC50(nM) = 1.5 |
| 25 | P19793_9HF | 9HF | n/a | 71461789 | CHEMBL2146901 | 1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)benzotriazole-5-carboxylic acid | n/a | |
| 26 | P19793_9RA | 9RA | DB00307 | 82146 | CHEMBL1023 | 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid | agonist | Ki(nM) = 14.0 IC50(nM) = 632.0 Kd(nM) = 7.0 EC50(nM) = 2.7 |
| 27 | P19793_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 28 | P19793_BGV | BGV | n/a | 3080597 | CHEMBL486997 | (3aR,4S,4aR,7aR,8R,9aS)-4a,8-dimethyl-3-methylidene-2,5-dioxo-2,3,3a,4,4a,5,7a,8,9,9a-decahydroazuleno[6,5-b]furan-4-yl acetate | n/a | |
| 29 | P19793_BM6 | BM6 | n/a | 3481673 | n/a | 4-[2-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-[1,3]DIOXOLAN-2-YL]-BENZOIC ACID | n/a | |
| 30 | P19793_BR | BR | n/a | 259 | n/a | BROMIDE ION | n/a | |
| 31 | P19793_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 32 | P19793_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 33 | P19793_CPS | CPS | n/a | 107670 | CHEMBL450950 | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE | n/a | |
| 34 | P19793_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 35 | P19793_E80 | E80 | n/a | 25006094 | CHEMBL1688383 | 6-[ethyl-[3-(2-methylpropoxy)-4-propan-2-yl-phenyl]amino]pyridine-3-carboxylic acid | n/a | |
| 36 | P19793_E8L | E8L | n/a | 46893393 | n/a | 6-[ethyl-[3-(2-methoxyethoxy)-4-propan-2-yl-phenyl]amino]pyridine-3-carboxylic acid | n/a | |
| 37 | P19793_E8O | E8O | n/a | 73775427 | CHEMBL3425765 | 6-[ethyl-[4-(2-methylpropoxy)-3-propan-2-yl-phenyl]amino]pyridine-3-carboxylic acid | n/a | |
| 38 | P19793_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 39 | P19793_F15 | F15 | n/a | 13849 | CHEMBL460025 | PENTADECANOIC ACID | n/a | |
| 40 | P19793_FMT | FMT | DB01942 | 284;18971002; | CHEMBL116736 | FORMIC ACID | n/a | |
| 41 | P19793_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 42 | P19793_HXA | HXA | DB03756 | 445580 | CHEMBL367149 | DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID | activator | |
| 43 | P19793_I5W | I5W | n/a | 131800942 | n/a | (~{E})-3-[3-(2-methyl-5-phenyl-phenyl)-4-oxidanyl-phenyl]prop-2-enoic acid | n/a | |
| 44 | P19793_J57 | J57 | n/a | 131800944 | CHEMBL5266566 | (~{E})-3-[4-oxidanyl-3-(3-propan-2-ylphenyl)phenyl]prop-2-enoic acid | n/a | |
| 45 | P19793_K08 | K08 | n/a | 73659166 | CHEMBL4531596 | 5-(2-{(1Z)-2-methyl-1-[4-(propan-2-yl)benzylidene]-1H-inden-3-yl}ethyl)-1H-tetrazole | n/a | |
| 46 | P19793_K09 | K09 | n/a | 54589362 | CHEMBL4520775 | 5-(2-{(1Z)-5-fluoro-2-methyl-1-[4-(propan-2-yl)benzylidene]-1H-inden-3-yl}ethyl)-1H-tetrazole | n/a | |
| 47 | P19793_L79 | L79 | n/a | n/a | n/a | (S)-(2E)-3[4-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-2-NAPHTHALENYL)TETRAHYDRO-1-BENZOFURAN-2-YL]-2-PROPENOIC ACID | n/a | |
| 48 | P19793_LFZ | LFZ | n/a | 23005221 | CHEMBL4451817 | 2-[4-[3,5-bis(trifluoromethyl)phenyl]phenyl]ethanoic acid | n/a | |
| 49 | P19793_LG2 | LG2 | DB01941 | 3922 | CHEMBL288436 | 6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)CYCLOPROPYL]PYRIDINE-3-CARBOXYLIC ACID | n/a | Ki(nM) = 3.0 IC50(nM) = 8.0 Kd(nM) = 3.0 EC50(nM) = 4.0 |
| 50 | P19793_LX8 | LX8 | n/a | 442148 | CHEMBL3577084 | 2-[(2S)-6-(2-methylbut-3-en-2-yl)-7-oxo-2,3-dihydro-7H-furo[3,2-g]chromen-2-yl]propan-2-yl acetate | n/a | |
| 51 | P19793_MES | MES | DB03814 | 78165;4478249; | CHEMBL1234276 | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | n/a | |
| 52 | P19793_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 53 | P19793_MLO | MLO | n/a | 72300 | CHEMBL180920 | 5,5'-di(prop-2-en-1-yl)biphenyl-2,2'-diol | n/a | |
| 54 | P19793_MPO | MPO | DB03434 | 70807;2723950; | CHEMBL1234443 | 3[N-MORPHOLINO]PROPANE SULFONIC ACID | n/a | |
| 55 | P19793_NO3 | NO3 | DB14049 | 943 | CHEMBL186200 | NITRATE ION | n/a | |
| 56 | P19793_OI2 | OI2 | n/a | 166642331 | n/a | (2E,4E,6Z,8E)-8-{3-[(2S)-butan-2-yl]-2-(3-methylbutyl)cyclohex-2-en-1-ylidene}-3,7-dimethylocta-2,4,6-trienoic acid | n/a | |
| 57 | P19793_OI5 | OI5 | n/a | 166642332 | CHEMBL5200645 | (2E,4E,6Z,8E)-3,7-dimethyl-8-[2-(3-methylbutyl)-3-propylcyclohex-2-en-1-ylidene]octa-2,4,6-trienoic acid | n/a | |
| 58 | P19793_P26 | P26 | n/a | 44141919 | n/a | 4-[2-(1,1,3,3-tetramethyl-2,3-dihydro-1H-inden-5-yl)-1,3-dioxolan-2-yl]benzoic acid | n/a | |
| 59 | P19793_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 60 | P19793_PGE | PGE | DB02327 | 8172 | CHEMBL1235259 | TRIETHYLENE GLYCOL | n/a | |
| 61 | P19793_PLM | PLM | DB03796 | 985;135369651; | CHEMBL82293 | PALMITIC ACID | n/a | |
| 62 | P19793_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 63 | P19793_R4M | R4M | n/a | 137349928 | n/a | (2E,6Z,8E)-3,7-dimethyl-8-[(4R)-4-methyl-3,4-dihydronaphthalen-1(2H)-ylidene]octa-2,6-dienoic acid | n/a | |
| 64 | P19793_REA | REA | DB00755 | 444795 | CHEMBL38 | RETINOIC ACID | agonist | |
| 65 | P19793_RHN | RHN | DB13174 | 10168 | CHEMBL418068 | 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid | n/a | |
| 66 | P19793_SJZ | SJZ | n/a | 131800946 | n/a | (~{E})-3-[3-(2-methyl-3-phenyl-phenyl)-4-oxidanyl-phenyl]prop-2-enoic acid | n/a | |
| 67 | P19793_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 68 | P19793_TBY | TBY | DB08601 | 5948 | n/a | tributylstannanyl | inhibitor | |
| 69 | P19793_UGW | UGW | n/a | 7311 | CHEMBL29873 | 2,4-di~{tert}-butylphenol | n/a | |
| 70 | P19793_WY5 | WY5 | n/a | 131750108 | CHEMBL4449685 | 7-oxidanyl-2-oxidanylidene-6-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)chromene-3-carboxylic acid | n/a | |
| 71 | P19793_WZ6 | WZ6 | n/a | 155294513 | CHEMBL4777069 | 1-[3-(2-ethoxyethoxy)-5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl]-2-(trifluoromethyl)benzimidazole-5-carboxylic acid | n/a | |
| 72 | P19793_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 73 | P19793_T2K | T2K | n/a | 155294511 | CHEMBL4874191 | 3-[5-[3,5-bis(chloranyl)phenyl]-4-phenyl-1,3-oxazol-2-yl]propanoic acid | n/a | |
| 74 | P19793_T72 | T72 | n/a | 155491000 | CHEMBL4855847 | 3-(5-(3,5-bis(trifluoromethyl)phenyl)-4-phenyloxazol-2-yl)propanoic acid | n/a | |
| 75 | P19793_T9T | T9T | n/a | 6460 | n/a | triphenylstannanyl | n/a | |
| 76 | P19793_LNL | LNL | DB00132 | 5280934 | CHEMBL8739 | alpha-Linolenic acid | n/a | |
| 77 | P19793_DB00210 | n/a | DB00210 | n/a | n/a | Adapalene | agonist | |
| 78 | P19793_DB00412 | n/a | DB00412 | n/a | n/a | Rosiglitazone | n/a | Kd(nM) = 15010.0 |
| 79 | P19793_DB00459 | n/a | DB00459 | n/a | n/a | Acitretin | agonist | |
| 80 | P19793_DB00749 | n/a | DB00749 | n/a | n/a | Etodolac | other | |
| 81 | P19793_DB00926 | n/a | DB00926 | n/a | n/a | Etretinate | agonist | |
| 82 | P19793_PEM | PEM | DB01393 | 39042 | CHEMBL264374 | Bezafibrate | agonist | |
| 83 | P19793_M9B | M9B | DB01436 | 5282181 | CHEMBL1601669 | Alfacalcidol | n/a | |
| 84 | P19793_PHT | PHT | DB02746 | 1017;18183610; | CHEMBL1045 | Phthalic Acid | n/a | |
| 85 | P19793_ELA | ELA | DB04224 | 637517 | CHEMBL460657 | Oleic Acid | n/a | |
| 86 | P19793_ACD | ACD | DB04557 | 444899 | CHEMBL15594 | Arachidonic Acid | n/a | |
| 87 | P19793_DB05956 | n/a | DB05956 | n/a | n/a | EVT-101 | n/a | |
| 88 | P19793_CI2 | CI2 | DB07557 | 92745 | CHEMBL486954 | 3,20-Pregnanedione | inhibitor | |
| 89 | P19793_GW9 | GW9 | DB07863 | 644213 | CHEMBL375270 | 2-chloro-5-nitro-N-phenylbenzamide | inhibitor | |
| 90 | P19793_L05 | L05 | DB08063 | 5288679 | CHEMBL189938 | 1-BENZYL-3-(4-METHOXYPHENYLAMINO)-4-PHENYLPYRROLE-2,5-DIONE | n/a | |
| 91 | P19793_PLB | PLB | DB08402 | 5289162 | CHEMBL1204498 | 2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID | n/a |