Gene name: CHRM3
Protein name: Muscarinic acetylcholine receptor
List of molecules and drugs that interact with protein P20309
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P20309_IXO | IXO | n/a | 10104167 | CHEMBL3121473 | 4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium | n/a | |
| 2 | P20309_WE9 | WE9 | n/a | 135445691 | CHEMBL1688 | 8-chloro-11-(4-methyl-4-oxo-4lambda~5~-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine | n/a | |
| 3 | P20309_WEC | WEC | n/a | 16103 | CHEMBL73538 | 11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine | n/a | |
| 4 | P20309_Y01 | Y01 | n/a | 65082 | n/a | CHOLESTEROL HEMISUCCINATE | n/a | |
| 5 | P20309_DB00185 | n/a | DB00185 | n/a | n/a | Cevimeline | agonist | |
| 6 | P20309_DB00193 | n/a | DB00193 | n/a | n/a | Tramadol | antagonist | |
| 7 | P20309_SCK | SCK | DB00202 | 5314 | CHEMBL703 | Succinylcholine | agonist | |
| 8 | P20309_DB00209 | n/a | DB00209 | n/a | n/a | Trospium | n/a | |
| 9 | P20309_DB00246 | n/a | DB00246 | n/a | n/a | Ziprasidone | antagonist | Ki(nM) = 1300.0 |
| 10 | P20309_DB00280 | n/a | DB00280 | n/a | n/a | Disopyramide | antagonist | |
| 11 | P20309_DB00332 | n/a | DB00332 | n/a | n/a | Ipratropium | antagonist | |
| 12 | P20309_DB00334 | n/a | DB00334 | n/a | n/a | Olanzapine | antagonist | Ki(nM) = 26.0 |
| 13 | P20309_DB00342 | n/a | DB00342 | n/a | n/a | Terfenadine | antagonist | |
| 14 | P20309_DB00363 | n/a | DB00363 | n/a | n/a | Clozapine | antagonist | Ki(nM) = 34.0 EC50(nM) = 10000.0 |
| 15 | P20309_DB00376 | n/a | DB00376 | n/a | n/a | Trihexyphenidyl | antagonist | Ki(nM) = 2.45 IC50(nM) = 26.0 |
| 16 | P20309_DB00383 | n/a | DB00383 | n/a | n/a | Oxyphencyclimine | antagonist | |
| 17 | P20309_DB00387 | n/a | DB00387 | n/a | n/a | Procyclidine | antagonist | Ki(nM) = 12.4 |
| 18 | P20309_DB00408 | n/a | DB00408 | n/a | n/a | Loxapine | binder | Ki(nM) = 122.0 |
| 19 | P20309_CCE | CCE | DB00411 | 2551 | CHEMBL965 | Carbamoylcholine | agonist | Ki(nM) = 10000.0 IC50(nM) = 880.0 Kd(nM) = 15400.0 EC50(nM) = 21.0 |
| 20 | P20309_HYO | HYO | DB00424 | n/a | CHEMBL1331216 | Hyoscyamine | antagonist | |
| 21 | P20309_C7H | C7H | DB00434 | 2913 | CHEMBL516 | Cyproheptadine | antagonist | Ki(nM) = 12.0 |
| 22 | P20309_IXX | IXX | DB00458 | 3696 | CHEMBL11 | Imipramine | antagonist | Ki(nM) = 60.0 |
| 23 | P20309_DB00462 | n/a | DB00462 | n/a | n/a | Methscopolamine bromide | antagonist | |
| 24 | P20309_Z80 | Z80 | DB00477 | 2726 | CHEMBL71 | Chlorpromazine | antagonist | Ki(nM) = 47.0 |
| 25 | P20309_DB00496 | n/a | DB00496 | n/a | n/a | Darifenacin | antagonist | Ki(nM) = 0.74 EC50(nM) = 11.0 |
| 26 | P20309_GMJ | GMJ | DB00502 | 3559 | CHEMBL54 | Haloperidol | n/a | Ki(nM) = 4670.0 |
| 27 | P20309_DB00505 | n/a | DB00505 | n/a | n/a | Tridihexethyl | antagonist | |
| 28 | P20309_DB00517 | n/a | DB00517 | n/a | n/a | Anisotropine methylbromide | antagonist | |
| 29 | P20309_DB00572 | n/a | DB00572 | n/a | n/a | Atropine | antagonist | Ki(nM) = 0.32 Kd(nM) = 0.9 |
| 30 | P20309_DB00599 | n/a | DB00599 | n/a | n/a | Thiopental | n/a | |
| 31 | P20309_DB00622 | n/a | DB00622 | n/a | n/a | Nicardipine | antagonist | |
| 32 | P20309_DB00725 | n/a | DB00725 | n/a | n/a | Homatropine methylbromide | antagonist | |
| 33 | P20309_DB00747 | n/a | DB00747 | n/a | n/a | Scopolamine | antagonist | |
| 34 | P20309_DB00767 | n/a | DB00767 | n/a | n/a | Benzquinamide | antagonist | |
| 35 | P20309_DB00804 | n/a | DB00804 | n/a | n/a | Dicyclomine | antagonist | |
| 36 | P20309_DB00809 | n/a | DB00809 | n/a | n/a | Tropicamide | antagonist | |
| 37 | P20309_DB00835 | n/a | DB00835 | n/a | n/a | Brompheniramine | antagonist | |
| 38 | P20309_DB00934 | n/a | DB00934 | n/a | n/a | Maprotiline | antagonist | |
| 39 | P20309_DB00940 | n/a | DB00940 | n/a | n/a | Methantheline | n/a | |
| 40 | P20309_DB00986 | n/a | DB00986 | n/a | n/a | Glycopyrronium | antagonist | Ki(nM) = 0.81 IC50(nM) = 0.251 |
| 41 | P20309_DB01019 | n/a | DB01019 | n/a | n/a | Bethanechol | agonist | |
| 42 | P20309_DB01036 | n/a | DB01036 | n/a | n/a | Tolterodine | antagonist | Ki(nM) = 3.2 |
| 43 | P20309_DB01062 | n/a | DB01062 | n/a | n/a | Oxybutynin | antagonist | Ki(nM) = 0.78 |
| 44 | P20309_DB01069 | n/a | DB01069 | n/a | n/a | Promethazine | antagonist | |
| 45 | P20309_9PL | 9PL | DB01085 | 5910 | CHEMBL550 | Pilocarpine | agonist | |
| 46 | P20309_DB01142 | no_lig_id | DB01142 | n/a | n/a | Doxepin | antagonist | |
| 47 | P20309_DSM | DSM | DB01151 | 2995 | CHEMBL72 | Desipramine | antagonist | Ki(nM) = 210.0 |
| 48 | P20309_DB01224 | n/a | DB01224 | n/a | n/a | Quetiapine | antagonist | Ki(nM) = 705.0 |
| 49 | P20309_DB01226 | n/a | DB01226 | n/a | n/a | Mivacurium | antagonist | |
| 50 | P20309_DB01231 | n/a | DB01231 | n/a | n/a | Diphenidol | antagonist | |
| 51 | P20309_9SC | 9SC | DB01238 | 60795 | CHEMBL1112 | Aripiprazole | ligand | Ki(nM) = 4677.0 IC50(nM) = 100000.0 |
| 52 | P20309_DB01239 | n/a | DB01239 | n/a | n/a | Chlorprothixene | antagonist | |
| 53 | P20309_DB01337 | n/a | DB01337 | n/a | n/a | Pancuronium | antagonist | |
| 54 | P20309_DB01338 | n/a | DB01338 | n/a | n/a | Pipecuronium | antagonist | |
| 55 | P20309_DB01403 | n/a | DB01403 | n/a | n/a | Methotrimeprazine | antagonist | |
| 56 | P20309_0HK | 0HK | DB01409 | n/a | CHEMBL1900528 | Tiotropium | antagonist | |
| 57 | P20309_DB01591 | n/a | DB01591 | n/a | n/a | Solifenacin | antagonist | Ki(nM) = 13.0 IC50(nM) = 24.0 EC50(nM) = 24.0 |
| 58 | P20309_DB01625 | n/a | DB01625 | n/a | n/a | Isopropamide | antagonist | |
| 59 | P20309_ACH | ACH | DB03128 | 187 | CHEMBL667 | Acetylcholine | n/a | Ki(nM) = 4200.0 EC50(nM) = 3.2 |
| 60 | P20309_DB04365 | n/a | DB04365 | n/a | n/a | Arecoline | n/a | Ki(nM) = 5700.0 IC50(nM) = 11000.0 EC50(nM) = 73.0 |
| 61 | P20309_DB04843 | n/a | DB04843 | n/a | n/a | Mepenzolate | antagonist | Ki(nM) = 2.6 |
| 62 | P20309_DB06153 | n/a | DB06153 | n/a | n/a | Pizotifen | antagonist | |
| 63 | P20309_DB06702 | n/a | DB06702 | n/a | n/a | Fesoterodine | antagonist | |
| 64 | P20309_DB06709 | n/a | DB06709 | n/a | n/a | Methacholine | agonist | |
| 65 | P20309_DB06787 | n/a | DB06787 | n/a | n/a | Hexocyclium | antagonist | |
| 66 | P20309_DB08897 | n/a | DB08897 | n/a | n/a | Aclidinium | antagonist | Ki(nM) = 0.07 IC50(nM) = 0.126 |
| 67 | P20309_DB09076 | n/a | DB09076 | n/a | n/a | Umeclidinium | antagonist | Ki(nM) = 0.06 IC50(nM) = 10000.0 |
| 68 | P20309_DB09089 | n/a | DB09089 | n/a | n/a | Trimebutine | antagonist | |
| 69 | P20309_DB09167 | n/a | DB09167 | n/a | n/a | Dosulepin | antagonist | |
| 70 | P20309_DB09185 | n/a | DB09185 | n/a | n/a | Viloxazine | antagonist | |
| 71 | P20309_DB09262 | n/a | DB09262 | n/a | n/a | Imidafenacin | antagonist | |
| 72 | P20309_DB09300 | n/a | DB09300 | n/a | n/a | Butylscopolamine | antagonist | |
| 73 | P20309_DB11181 | n/a | DB11181 | n/a | n/a | Homatropine | antagonist | |
| 74 | P20309_DB11235 | n/a | DB11235 | n/a | n/a | Thonzylamine | antagonist | |
| 75 | P20309_DB12278 | n/a | DB12278 | n/a | n/a | Propiverine | antagonist | |
| 76 | P20309_DB13581 | n/a | DB13581 | n/a | n/a | Rociverine | antagonist | |
| 77 | P20309_DB13720 | n/a | DB13720 | n/a | n/a | Diphemanil | antagonist | |
| 78 | P20309_DB14185 | n/a | DB14185 | n/a | n/a | Aripiprazole lauroxil | n/a |